PL193428B1 - Arylopiperazyna mająca aktywność na receptorze 1Aserotoniny, związek pośredni, kompozycja farmaceutyczna oraz ich zastosowanie - Google Patents

Arylopiperazyna mająca aktywność na receptorze 1Aserotoniny, związek pośredni, kompozycja farmaceutyczna oraz ich zastosowanie

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Publication number
PL193428B1
PL193428B1 PL98342170A PL34217098A PL193428B1 PL 193428 B1 PL193428 B1 PL 193428B1 PL 98342170 A PL98342170 A PL 98342170A PL 34217098 A PL34217098 A PL 34217098A PL 193428 B1 PL193428 B1 PL 193428B1
Authority
PL
Poland
Prior art keywords
phenyl
piperazine
pharmaceutically acceptable
arylpiperazine
alkyl
Prior art date
Application number
PL98342170A
Other languages
English (en)
Polish (pl)
Other versions
PL342170A1 (en
Inventor
Alexander Glenn Godfrey
Daniel Timothy Kohlman
John Cunningham O'toole
Yao-Chang Xu
Tony Yantao Zhang
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PL342170A1 publication Critical patent/PL342170A1/xx
Publication of PL193428B1 publication Critical patent/PL193428B1/pl

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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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PL98342170A 1997-12-16 1998-12-08 Arylopiperazyna mająca aktywność na receptorze 1Aserotoniny, związek pośredni, kompozycja farmaceutyczna oraz ich zastosowanie PL193428B1 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US6972297P 1997-12-16 1997-12-16
US6979197P 1997-12-16 1997-12-16
US8958998P 1998-06-17 1998-06-17
PCT/US1998/026008 WO1999031077A1 (en) 1997-12-16 1998-12-08 Arylpiperazines having activity at the serotonin 1a receptor

Publications (2)

Publication Number Publication Date
PL342170A1 PL342170A1 (en) 2001-05-21
PL193428B1 true PL193428B1 (pl) 2007-02-28

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PL98342170A PL193428B1 (pl) 1997-12-16 1998-12-08 Arylopiperazyna mająca aktywność na receptorze 1Aserotoniny, związek pośredni, kompozycja farmaceutyczna oraz ich zastosowanie

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US (9) US6239135B1 (es)
EP (2) EP0924205B1 (es)
JP (2) JP2002508364A (es)
KR (1) KR100539651B1 (es)
CN (2) CN1227241C (es)
AR (1) AR017864A1 (es)
AT (1) ATE296296T1 (es)
AU (1) AU747040B2 (es)
BR (1) BR9814280A (es)
CA (2) CA2506802A1 (es)
CO (1) CO4980859A1 (es)
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DK (1) DK0924205T3 (es)
EA (1) EA003703B1 (es)
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HU (1) HU226409B1 (es)
ID (1) ID26930A (es)
IL (3) IL136723A0 (es)
MY (1) MY125868A (es)
NO (1) NO317098B1 (es)
NZ (1) NZ505220A (es)
PE (1) PE20000134A1 (es)
PL (1) PL193428B1 (es)
PT (1) PT924205E (es)
SV (1) SV1998000148A (es)
TR (1) TR200001727T2 (es)
TW (1) TW520366B (es)
UA (1) UA66370C2 (es)
WO (1) WO1999031077A1 (es)
ZA (1) ZA9811473B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA66370C2 (en) * 1997-12-16 2004-05-17 Lilly Co Eli Arylpiperazines having activity to setotonin 1 receptors
ES2393582T3 (es) 1999-09-03 2012-12-26 Apbi Holdings, Llc Procedimiento de utilización de inhibidores de la recaptación de serotonina selectivos de inicio rápido de acción para el tratamiento de las disfunciones sexuales
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