SU433680A3 - - Google Patents

Info

Publication number
SU433680A3
SU433680A3 SU1631976A SU1631976A SU433680A3 SU 433680 A3 SU433680 A3 SU 433680A3 SU 1631976 A SU1631976 A SU 1631976A SU 1631976 A SU1631976 A SU 1631976A SU 433680 A3 SU433680 A3 SU 433680A3
Authority
SU
USSR - Soviet Union
Prior art keywords
mol
hydrochloric acid
solution
water
recrystallization
Prior art date
Application number
SU1631976A
Other languages
English (en)
Russian (ru)
Original Assignee
иностранцы Мишель Тюрен, Клод П.Форан, М.Рвйно , Жанин Томас
Франци Иностранна фириа С.А.Делаланд Фрашщ
Способ Получения Пройзводнух Бензгидрилпиперазина
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by иностранцы Мишель Тюрен, Клод П.Форан, М.Рвйно , Жанин Томас, Франци Иностранна фириа С.А.Делаланд Фрашщ, Способ Получения Пройзводнух Бензгидрилпиперазина filed Critical иностранцы Мишель Тюрен, Клод П.Форан, М.Рвйно , Жанин Томас
Application granted granted Critical
Publication of SU433680A3 publication Critical patent/SU433680A3/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SU1631976A 1970-03-18 1971-03-18 SU433680A3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR707009595A FR2081579B1 (es) 1970-03-18 1970-03-18

Publications (1)

Publication Number Publication Date
SU433680A3 true SU433680A3 (es) 1974-06-25

Family

ID=9052424

Family Applications (1)

Application Number Title Priority Date Filing Date
SU1631976A SU433680A3 (es) 1970-03-18 1971-03-18

Country Status (13)

Country Link
BE (1) BE763609A (es)
CH (1) CH518952A (es)
CS (1) CS168555B2 (es)
DE (1) DE2111776A1 (es)
ES (1) ES389129A1 (es)
FR (1) FR2081579B1 (es)
GB (1) GB1280290A (es)
IL (1) IL36345A (es)
LU (1) LU62723A1 (es)
NL (1) NL7103618A (es)
SE (1) SE380022B (es)
SU (1) SU433680A3 (es)
ZA (1) ZA711334B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154078C (da) * 1981-02-06 1989-05-22 Ucb Sa Analogifremgangsmaade til fremstilling af 2-(2-(4-(diphenyl-methyl)-1-piperazinyl)ethoxy)-acetamider eller syreadditionssalte heraf
FR2527605A1 (fr) * 1982-05-25 1983-12-02 Fordonal Sa Derives de piperazine, procede de fabrication et medicaments en resultant
JPS59101475A (ja) * 1982-12-02 1984-06-12 Nippon Chemiphar Co Ltd 新規ピペラジン誘導体およびその製造法ならびにこれを含有する脳循環改善剤
JPS59118765A (ja) * 1982-12-24 1984-07-09 Fujisawa Pharmaceut Co Ltd ピペラジン誘導体
JP2624372B2 (ja) * 1990-11-15 1997-06-25 宇部興産株式会社 ジアリールメトキシピペリジン誘導体
US7355042B2 (en) 2001-10-16 2008-04-08 Hypnion, Inc. Treatment of CNS disorders using CNS target modulators
EA014959B3 (ru) 2006-06-28 2014-10-30 Амген Инк. Ингибиторы глицинового переносчика-1

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1049383B (de) * 1959-01-29 Forest Brüssel Henri Morren (Belgien) Verfahren zur Herstellung von antihistaminaktiven Pipcrazinderivaten
BE649848A (es) * 1963-07-03 1964-12-29

Also Published As

Publication number Publication date
BE763609A (fr) 1971-09-01
ZA711334B (en) 1971-11-24
IL36345A (en) 1974-01-14
ES389129A1 (es) 1973-06-01
CS168555B2 (es) 1976-06-29
LU62723A1 (es) 1971-10-13
FR2081579B1 (es) 1973-04-06
CH518952A (fr) 1972-02-15
IL36345A0 (en) 1971-05-26
DE2111776A1 (de) 1971-10-07
SE380022B (es) 1975-10-27
GB1280290A (en) 1972-07-05
NL7103618A (es) 1971-09-21
FR2081579A1 (es) 1971-12-10

Similar Documents

Publication Publication Date Title
SU682134A3 (ru) Способ получени производных эритромицина или их солей
SU433680A3 (es)
US4298614A (en) 5'-Aminoalkyl-4',4-dialkylpsoralens
Wilson et al. Synthesis and properties of neopyrithiamine salts
Heymann et al. Derivatives of p, p'-Diaminodiphenyl Sulfone1a
Bonner et al. Amide derivatives of D-glucosamine
Hunter et al. The A New Sympatholytic Agent
US2468912A (en) Alkyl esters of alpha-acyl, alpha-acylamino, beta(3-indole)-propionic acid
SU607549A3 (ru) Способ получени производных карбалкокситиоуреидобензола
SU569287A3 (ru) Способ получени производных бензгидрилоксиалкиламина или их солей
US3988371A (en) Meta-[2-(benzylamino)-ethyl] benzoic acid amides
US2970159A (en) Hydrazine derivatives
SU423291A3 (es)
SU432718A3 (ru) Способ получения2-замещенных производных1-циннамилбензимидазола
Łukasiewicz Reactions of trihalogenoacetic acids—II: The reaction of trichloro-and tribromoacetic acids with methylenebisamine derivatives
Labriola et al. Studies in argentine plants. XI. The partial structure of erysovine, erysodine, and erysopine
US3414586A (en) Acetoamido derivatives
US4002633A (en) Novel compounds: N-disubstituted amino-ethyl esters of raubasine of the general formula
US2697095A (en) Penicillin salts of glycine-diphenylamides
SU436057A1 (ru) СПОСОБ ПОЛУЧЕНИЯ ИЗОПРОПИЛИДЕНОВЫХ ПРОИЗВОДНЫХ ПИРИДОКСИНАВ ПТ5ФОНЯ mmim
SU552031A3 (ru) Способ получени производных бензимидазола
US3808204A (en) 1-((5-nitrofurfurylidene)amino)hexahydrobenzimidazol-2(3h)-one
SU364611A1 (ru) Способ получения производных гидантоина
Bloch et al. Studies on Triazines. II. Lactim—Lactam Isomerism in Substituted Tetrahydrotriazines
Cook et al. Isolation of acetic acid from mammalian liver