BE763609A - Nouveaux derives de la benzhydryl piperazine leur procede de preparation et leur application en therapeutique ( - Google Patents
Nouveaux derives de la benzhydryl piperazine leur procede de preparation et leur application en therapeutique (Info
- Publication number
- BE763609A BE763609A BE763609A BE763609A BE763609A BE 763609 A BE763609 A BE 763609A BE 763609 A BE763609 A BE 763609A BE 763609 A BE763609 A BE 763609A BE 763609 A BE763609 A BE 763609A
- Authority
- BE
- Belgium
- Prior art keywords
- preparation process
- therapeutic application
- new derivatives
- benzhydryl piperazine
- benzhydryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR707009595A FR2081579B1 (fr) | 1970-03-18 | 1970-03-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
BE763609A true BE763609A (fr) | 1971-09-01 |
Family
ID=9052424
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE763609A BE763609A (fr) | 1970-03-18 | 1971-03-01 | Nouveaux derives de la benzhydryl piperazine leur procede de preparation et leur application en therapeutique ( |
Country Status (13)
Country | Link |
---|---|
BE (1) | BE763609A (fr) |
CH (1) | CH518952A (fr) |
CS (1) | CS168555B2 (fr) |
DE (1) | DE2111776A1 (fr) |
ES (1) | ES389129A1 (fr) |
FR (1) | FR2081579B1 (fr) |
GB (1) | GB1280290A (fr) |
IL (1) | IL36345A (fr) |
LU (1) | LU62723A1 (fr) |
NL (1) | NL7103618A (fr) |
SE (1) | SE380022B (fr) |
SU (1) | SU433680A3 (fr) |
ZA (1) | ZA711334B (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0058146A1 (fr) * | 1981-02-06 | 1982-08-18 | U C B, S.A. | Nouveaux acides 2-(4-(diphénylméthyl)-1-pipérazinyl)-acétiques et leurs amides, leurs procédés de préparation et compositions thérapeutiques |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3318577A1 (de) * | 1982-05-25 | 1983-12-01 | Fordonal S.A., Madrid | Piperazinderivate |
JPS59101475A (ja) * | 1982-12-02 | 1984-06-12 | Nippon Chemiphar Co Ltd | 新規ピペラジン誘導体およびその製造法ならびにこれを含有する脳循環改善剤 |
JPS59118765A (ja) * | 1982-12-24 | 1984-07-09 | Fujisawa Pharmaceut Co Ltd | ピペラジン誘導体 |
JP2624372B2 (ja) * | 1990-11-15 | 1997-06-25 | 宇部興産株式会社 | ジアリールメトキシピペリジン誘導体 |
US7355042B2 (en) | 2001-10-16 | 2008-04-08 | Hypnion, Inc. | Treatment of CNS disorders using CNS target modulators |
PL2041088T3 (pl) | 2006-06-28 | 2014-07-31 | Amgen Inc | Inhibitory transportera-1 glicyny |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1049383B (de) * | 1959-01-29 | Forest Brüssel Henri Morren (Belgien) | Verfahren zur Herstellung von antihistaminaktiven Pipcrazinderivaten | |
BE649848A (fr) * | 1963-07-03 | 1964-12-29 |
-
1970
- 1970-03-18 FR FR707009595A patent/FR2081579B1/fr not_active Expired
-
1971
- 1971-03-01 BE BE763609A patent/BE763609A/fr unknown
- 1971-03-02 ZA ZA711334A patent/ZA711334B/xx unknown
- 1971-03-04 IL IL36345A patent/IL36345A/xx unknown
- 1971-03-04 LU LU62723D patent/LU62723A1/xx unknown
- 1971-03-10 CH CH351571A patent/CH518952A/fr not_active IP Right Cessation
- 1971-03-11 ES ES389129A patent/ES389129A1/es not_active Expired
- 1971-03-11 DE DE19712111776 patent/DE2111776A1/de active Pending
- 1971-03-16 CS CS1906A patent/CS168555B2/cs unknown
- 1971-03-16 SE SE7103377A patent/SE380022B/xx unknown
- 1971-03-18 NL NL7103618A patent/NL7103618A/xx unknown
- 1971-03-18 SU SU1631976A patent/SU433680A3/ru active
- 1971-04-19 GB GB23880/71A patent/GB1280290A/en not_active Expired
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0058146A1 (fr) * | 1981-02-06 | 1982-08-18 | U C B, S.A. | Nouveaux acides 2-(4-(diphénylméthyl)-1-pipérazinyl)-acétiques et leurs amides, leurs procédés de préparation et compositions thérapeutiques |
US4525358A (en) * | 1981-02-06 | 1985-06-25 | Ucb Pharmaceuticals, Inc. | 2-[4-(Diphenylmethyl)-1-piperazinyl]-acetic acids and their amides |
Also Published As
Publication number | Publication date |
---|---|
LU62723A1 (fr) | 1971-10-13 |
ES389129A1 (es) | 1973-06-01 |
FR2081579B1 (fr) | 1973-04-06 |
CH518952A (fr) | 1972-02-15 |
IL36345A (en) | 1974-01-14 |
NL7103618A (fr) | 1971-09-21 |
CS168555B2 (fr) | 1976-06-29 |
SU433680A3 (fr) | 1974-06-25 |
SE380022B (fr) | 1975-10-27 |
DE2111776A1 (de) | 1971-10-07 |
FR2081579A1 (fr) | 1971-12-10 |
ZA711334B (en) | 1971-11-24 |
GB1280290A (en) | 1972-07-05 |
IL36345A0 (en) | 1971-05-26 |
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