SU426361A3 - СПОСОБ ПОЛУЧЕНИЯ ( + )-р-АМИНО- р- - Google Patents
СПОСОБ ПОЛУЧЕНИЯ ( + )-р-АМИНО- р-Info
- Publication number
- SU426361A3 SU426361A3 SU1643458A SU1643458A SU426361A3 SU 426361 A3 SU426361 A3 SU 426361A3 SU 1643458 A SU1643458 A SU 1643458A SU 1643458 A SU1643458 A SU 1643458A SU 426361 A3 SU426361 A3 SU 426361A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- amino
- acid
- general formula
- carboxyl group
- compound
- Prior art date
Links
- 238000000034 method Methods 0.000 title description 4
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 8
- 239000002253 acid Substances 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 6
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 3
- 230000007062 hydrolysis Effects 0.000 description 3
- 238000006460 hydrolysis reaction Methods 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000007800 oxidant agent Substances 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 125000003762 3,4-dimethoxyphenyl group Chemical group [H]C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1* 0.000 description 1
- 235000008733 Citrus aurantifolia Nutrition 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 1
- 235000011941 Tilia x europaea Nutrition 0.000 description 1
- 150000008065 acid anhydrides Chemical class 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 125000002252 acyl group Chemical group 0.000 description 1
- 150000001540 azides Chemical class 0.000 description 1
- 150000001735 carboxylic acids Chemical class 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 125000004093 cyano group Chemical group *C#N 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000032050 esterification Effects 0.000 description 1
- 238000005886 esterification reaction Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- AEOCXXJPGCBFJA-UHFFFAOYSA-N ethionamide Chemical compound CCC1=CC(C(N)=S)=CC=N1 AEOCXXJPGCBFJA-UHFFFAOYSA-N 0.000 description 1
- -1 formic Chemical class 0.000 description 1
- 150000004820 halides Chemical class 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- 150000007529 inorganic bases Chemical class 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 239000004571 lime Substances 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 150000007530 organic bases Chemical class 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 150000003460 sulfonic acids Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH527370A CH554832A (de) | 1970-04-09 | 1970-04-09 | Verfahren zur herstellung von neuen (beta)-amino-(beta)-phenylpropionsaeuren, -estern und -amiden. |
| CH1081970A CH551944A (de) | 1970-07-16 | 1970-07-16 | Verfahren zur herstellung der (+)-(beta)-amino-(beta)-(3,4-dimethoxy-phenyl)-propionsaeure. |
| CH341571 | 1971-03-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU426361A3 true SU426361A3 (ru) | 1974-04-30 |
Family
ID=27174323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1643458A SU426361A3 (ru) | 1970-04-09 | 1971-04-08 | СПОСОБ ПОЛУЧЕНИЯ ( + )-р-АМИНО- р- |
Country Status (13)
| Country | Link |
|---|---|
| AR (3) | AR195161A1 (enExample) |
| BE (1) | BE765473A (enExample) |
| CA (1) | CA964672A (enExample) |
| DE (1) | DE2115801A1 (enExample) |
| ES (1) | ES390009A1 (enExample) |
| FR (1) | FR2092024A1 (enExample) |
| IE (1) | IE35040B1 (enExample) |
| IL (1) | IL36519A (enExample) |
| NL (1) | NL7104793A (enExample) |
| NO (1) | NO133755C (enExample) |
| PL (1) | PL84491B1 (enExample) |
| SE (1) | SE377458B (enExample) |
| SU (1) | SU426361A3 (enExample) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3740439A (en) * | 1968-06-24 | 1973-06-19 | Ciba Geigy Corp | Treating hypertension with beta-aminoalkane carboxylic acids |
-
1971
- 1971-03-29 CA CA108,916A patent/CA964672A/en not_active Expired
- 1971-03-30 IE IE408/71A patent/IE35040B1/xx unknown
- 1971-03-31 IL IL36519A patent/IL36519A/en unknown
- 1971-04-01 DE DE19712115801 patent/DE2115801A1/de active Pending
- 1971-04-06 NO NO1332/71A patent/NO133755C/no unknown
- 1971-04-07 PL PL1971147407A patent/PL84491B1/pl unknown
- 1971-04-07 SE SE7104543A patent/SE377458B/xx unknown
- 1971-04-07 ES ES390009A patent/ES390009A1/es not_active Expired
- 1971-04-08 NL NL7104793A patent/NL7104793A/xx unknown
- 1971-04-08 SU SU1643458A patent/SU426361A3/ru active
- 1971-04-08 BE BE765473A patent/BE765473A/xx unknown
- 1971-04-08 FR FR7112481A patent/FR2092024A1/fr active Granted
-
1972
- 1972-01-27 AR AR240258A patent/AR195161A1/es active
- 1972-01-27 AR AR240259A patent/AR196985A1/es active
-
1973
- 1973-05-21 AR AR248144A patent/AR194555A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| BE765473A (fr) | 1971-10-08 |
| NL7104793A (enExample) | 1971-10-12 |
| FR2092024A1 (en) | 1972-01-21 |
| NO133755B (enExample) | 1976-03-15 |
| IL36519A0 (en) | 1971-05-26 |
| IL36519A (en) | 1974-12-31 |
| DE2115801A1 (de) | 1971-10-21 |
| FR2092024B1 (enExample) | 1974-04-12 |
| CA964672A (en) | 1975-03-18 |
| NO133755C (enExample) | 1976-06-23 |
| AR195161A1 (es) | 1973-09-19 |
| IE35040L (en) | 1971-10-09 |
| AR196985A1 (es) | 1974-03-08 |
| IE35040B1 (en) | 1975-10-29 |
| SE377458B (enExample) | 1975-07-07 |
| ES390009A1 (es) | 1974-04-16 |
| PL84491B1 (en) | 1976-04-30 |
| AR194555A1 (es) | 1973-07-23 |
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