SU1393309A3 - Способ герметизации твердооболочной желатиновой капсулы,состо щей из телескопически соединенных,коаксиально расположенных крышки и корпуса - Google Patents
Способ герметизации твердооболочной желатиновой капсулы,состо щей из телескопически соединенных,коаксиально расположенных крышки и корпуса Download PDFInfo
- Publication number
- SU1393309A3 SU1393309A3 SU833655358A SU3655358A SU1393309A3 SU 1393309 A3 SU1393309 A3 SU 1393309A3 SU 833655358 A SU833655358 A SU 833655358A SU 3655358 A SU3655358 A SU 3655358A SU 1393309 A3 SU1393309 A3 SU 1393309A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- sealing
- capsules
- capsule
- heating
- sealing liquid
- Prior art date
Links
- 238000007789 sealing Methods 0.000 title claims abstract description 24
- 238000000034 method Methods 0.000 title claims abstract description 13
- 239000007903 gelatin capsule Substances 0.000 title claims abstract description 4
- 239000002775 capsule Substances 0.000 claims abstract description 25
- 238000009736 wetting Methods 0.000 claims abstract description 5
- 238000001035 drying Methods 0.000 claims abstract description 3
- 239000007788 liquid Substances 0.000 claims description 15
- 150000003839 salts Chemical class 0.000 claims description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 10
- 108010010803 Gelatin Proteins 0.000 claims description 9
- 229920000159 gelatin Polymers 0.000 claims description 9
- 239000008273 gelatin Substances 0.000 claims description 9
- 235000019322 gelatine Nutrition 0.000 claims description 9
- 235000011852 gelatine desserts Nutrition 0.000 claims description 9
- 238000010438 heat treatment Methods 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 239000007864 aqueous solution Substances 0.000 claims description 7
- 238000002844 melting Methods 0.000 claims description 6
- 230000008018 melting Effects 0.000 claims description 6
- 239000003960 organic solvent Substances 0.000 claims description 6
- 239000000243 solution Substances 0.000 claims description 6
- 239000002253 acid Substances 0.000 claims description 4
- 150000007513 acids Chemical class 0.000 claims description 4
- 150000001450 anions Chemical class 0.000 claims description 4
- 150000001768 cations Chemical class 0.000 claims description 4
- 229910052751 metal Inorganic materials 0.000 claims description 4
- 239000002184 metal Substances 0.000 claims description 4
- 239000000839 emulsion Substances 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 229920000642 polymer Polymers 0.000 claims description 2
- -1 polytetrafluoroethylene Polymers 0.000 claims description 2
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims description 2
- 239000004810 polytetrafluoroethylene Substances 0.000 claims description 2
- 238000005507 spraying Methods 0.000 claims description 2
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 230000001464 adherent effect Effects 0.000 claims 1
- JZZIHCLFHIXETF-UHFFFAOYSA-N dimethylsilicon Chemical compound C[Si]C JZZIHCLFHIXETF-UHFFFAOYSA-N 0.000 claims 1
- 239000012460 protein solution Substances 0.000 claims 1
- 239000012530 fluid Substances 0.000 abstract description 6
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 4
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 4
- 102000035195 Peptidases Human genes 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000001935 peptisation Methods 0.000 description 1
- 230000010287 polarization Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
- A61J3/072—Sealing capsules, e.g. rendering them tamper-proof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4883—Capsule finishing, e.g. dyeing, aromatising, polishing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
- B29C65/48—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding
- B29C65/4895—Solvent bonding, i.e. the surfaces of the parts to be joined being treated with solvents, swelling or softening agents, without adhesives
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/01—General aspects dealing with the joint area or with the area to be joined
- B29C66/05—Particular design of joint configurations
- B29C66/10—Particular design of joint configurations particular design of the joint cross-sections
- B29C66/11—Joint cross-sections comprising a single joint-segment, i.e. one of the parts to be joined comprising a single joint-segment in the joint cross-section
- B29C66/112—Single lapped joints
- B29C66/1122—Single lap to lap joints, i.e. overlap joints
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/50—General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
- B29C66/51—Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
- B29C66/54—Joining several hollow-preforms, e.g. half-shells, to form hollow articles, e.g. for making balls, containers; Joining several hollow-preforms, e.g. half-cylinders, to form tubular articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/50—General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
- B29C66/51—Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
- B29C66/54—Joining several hollow-preforms, e.g. half-shells, to form hollow articles, e.g. for making balls, containers; Joining several hollow-preforms, e.g. half-cylinders, to form tubular articles
- B29C66/542—Joining several hollow-preforms, e.g. half-shells, to form hollow articles, e.g. for making balls, containers; Joining several hollow-preforms, e.g. half-cylinders, to form tubular articles joining hollow covers or hollow bottoms to open ends of container bodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
- A61G2203/00—General characteristics of devices
- A61G2203/30—General characteristics of devices characterised by sensor means
- A61G2203/46—General characteristics of devices characterised by sensor means for temperature
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
- B29C65/48—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding
- B29C65/52—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding characterised by the way of applying the adhesive
- B29C65/54—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding characterised by the way of applying the adhesive between pre-assembled parts
- B29C65/548—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding characterised by the way of applying the adhesive between pre-assembled parts by capillarity
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
- B29C66/71—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the composition of the plastics material of the parts to be joined
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/712—Containers; Packaging elements or accessories, Packages
- B29L2031/7174—Capsules
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S220/00—Receptacles
- Y10S220/34—Anti-tamper pharmaceutical capsules, e.g. tamper indicating or resistant
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
- Y10T156/17—Surface bonding means and/or assemblymeans with work feeding or handling means
- Y10T156/1798—Surface bonding means and/or assemblymeans with work feeding or handling means with liquid adhesive or adhesive activator applying means
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
- Closing Of Containers (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Formation And Processing Of Food Products (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/468,022 US4539060A (en) | 1983-02-18 | 1983-02-18 | Apparatus and method of sealing capsules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU1393309A3 true SU1393309A3 (ru) | 1988-04-30 |
Family
ID=23858126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU833655358A SU1393309A3 (ru) | 1983-02-18 | 1983-10-17 | Способ герметизации твердооболочной желатиновой капсулы,состо щей из телескопически соединенных,коаксиально расположенных крышки и корпуса |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4539060A (enExample) |
| EP (1) | EP0116743B1 (enExample) |
| JP (1) | JPS59156349A (enExample) |
| KR (1) | KR890000206B1 (enExample) |
| AT (1) | ATE33346T1 (enExample) |
| AU (1) | AU559678B2 (enExample) |
| BR (1) | BR8306208A (enExample) |
| CA (1) | CA1255271A (enExample) |
| DE (1) | DE3376197D1 (enExample) |
| ES (1) | ES8501976A1 (enExample) |
| IE (1) | IE56363B1 (enExample) |
| IN (1) | IN160442B (enExample) |
| PH (1) | PH20191A (enExample) |
| SU (1) | SU1393309A3 (enExample) |
| YU (1) | YU44447B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2404735C2 (ru) * | 2006-08-04 | 2010-11-27 | Пфайзер Продактс Инк. | Способ и устройство для герметизации капсул |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59105455A (ja) * | 1982-11-23 | 1984-06-18 | ワ−ナ−・ランバ−ト・カンパニ− | カプセルを封止するための装置及び方法 |
| US4656066A (en) * | 1982-12-20 | 1987-04-07 | Warner-Lambert Company | Apparatus and method for sealing capsules |
| US4820364A (en) * | 1983-05-23 | 1989-04-11 | Capsulbond Incorporated | Method for sealing capsules |
| ATE32560T1 (de) * | 1983-06-13 | 1988-03-15 | Capsulbond Inc | Vorrichtung zum schliessen von kapseln. |
| IE58468B1 (en) * | 1984-10-25 | 1993-09-22 | Warner Lambert Co | Method for sealing capsules and capsule |
| GB2172570B (en) * | 1985-03-21 | 1989-06-21 | Warner Lambert Co | Hard gelatin capsules. |
| CN1003578B (zh) * | 1984-10-25 | 1989-03-15 | 沃纳·兰伯特公司 | 改进的胶囊形状 |
| CH674800A5 (enExample) * | 1986-03-12 | 1990-07-31 | Warner Lambert Co | |
| CA1308357C (en) * | 1987-01-28 | 1992-10-06 | Tohru Chiba | Method for the preparation of a coated solid medicament |
| US4724019A (en) * | 1987-03-20 | 1988-02-09 | Warner-Lambert Company | Method and apparatus for sealing capsules |
| US4734149A (en) * | 1987-03-20 | 1988-03-29 | Warner-Lambert Company | Apparatus for heatsealing gelatin capsules containing a medicament |
| US4940499A (en) * | 1989-05-23 | 1990-07-10 | Warner-Lambert Company | Method and apparatus for sealing capsules containing medicaments |
| US5188688A (en) * | 1990-07-20 | 1993-02-23 | Minnesota Mining And Manufacturing Company | Method of sealing a gelatin capsule |
| GB9416902D0 (en) * | 1994-08-20 | 1994-10-12 | Scherer Corp R P | Hydrophilic controlled release device |
| EP1072245A1 (en) | 1999-07-30 | 2001-01-31 | Warner-Lambert Company | Method and apparatus for sealing capsules and capsules suitable for use in said method and apparatus |
| US6887916B2 (en) * | 2000-12-28 | 2005-05-03 | Kimberly-Clark Worldwide, Inc. | Materials having controlled shrinkage and patterns and methods of making same |
| EP1262174A1 (en) | 2001-06-01 | 2002-12-04 | Celanese Ventures GmbH | Two part hard shell capsule made of poly(1,4-alpha-D-glucane) and starch |
| WO2003016165A1 (en) | 2001-08-16 | 2003-02-27 | Warner-Lambert Company Llc | Water soluble packaging |
| CA2503510C (en) * | 2002-09-26 | 2014-12-02 | Probiohealth, Llc | Prebiotic and preservative uses of oil-emulsified probiotic encapsulations |
| US8895060B2 (en) | 2002-09-26 | 2014-11-25 | Vita-Herb Nutriceuticals, Inc. | Methods and apparatus for sealing capsules |
| EP1459725B1 (en) | 2003-03-21 | 2007-10-17 | Warner-Lambert Company LLC | Apparatus for and method of sealing capsules |
| GB2401345A (en) * | 2003-05-03 | 2004-11-10 | Reckitt Benckiser | Atomised aqueous composition sealing of water soluble members |
| US8377471B2 (en) * | 2005-08-09 | 2013-02-19 | Capsugel Belgium Nv | Container |
| US20070036830A1 (en) * | 2005-08-09 | 2007-02-15 | Stef Vanquickenborne | Container |
| US20070053972A1 (en) * | 2005-09-08 | 2007-03-08 | Cadbury Adams Usa Llc. | Gelatin capsules containing actives |
| US20080038334A1 (en) * | 2006-08-08 | 2008-02-14 | John Zazula | Method for producing and a system for cooling a hot-filled softgel capsule |
| RU2415068C2 (ru) * | 2006-10-24 | 2011-03-27 | Пфайзер Продактс Инк. | Транспортировочная линия |
| KR101170283B1 (ko) | 2006-10-27 | 2012-07-31 | 화이자 프로덕츠 인코포레이티드 | 하이드록시프로필 메틸 셀룰로스 경질 캡슐 및 이의 제조 방법 |
| ES2602571T3 (es) | 2007-02-15 | 2017-02-21 | Qualicaps Co., Ltd. | Elemento de sellado en banda para cápsulas duras que presentan PEG encapsulado en las mismas |
| PT103765A (pt) * | 2007-06-20 | 2008-12-22 | Inst Superior Tecnico | Síntese e aplicação de uma família de novos materiais resultantes do cruzamento entre gelatina e sais orgânicos |
| US8810259B2 (en) | 2009-11-13 | 2014-08-19 | Capsugel Belgium Nv | Method of inspection of sealed capsules with a process of determination of the quality of the seal and related equipment for in-line inspection |
| WO2012028702A1 (de) | 2010-09-02 | 2012-03-08 | Innogel Ag | Hartkapsel auf stärkebasis sowie tauchbeschichtungszusammensetzung, tauchbad und verfahren zur herstellung derselben |
| CN101953816B (zh) * | 2010-09-08 | 2015-01-07 | 浙江昂利康胶囊有限公司 | 药用空心胶囊、制备方法及其制造设备 |
| EP2720686A4 (en) * | 2011-06-15 | 2014-12-17 | Orient Pharma Co Ltd | MULTILAYER CAPSULE AND MANUFACTURING METHOD THEREFOR |
| MX363958B (es) * | 2011-10-06 | 2019-04-09 | Combocap Inc | Un metodo y aparato para fabricar una capsula. |
| CA2870033C (en) | 2012-05-02 | 2017-04-18 | Capsugel France SAS | Aqueous dispersions of controlled release polymers and shells and capsules thereof |
| WO2014197415A1 (en) | 2013-06-04 | 2014-12-11 | Monosol Llc | Water-soluble film sealing solutions, related methods, and related articles |
| US20160256399A1 (en) | 2013-11-04 | 2016-09-08 | Capsugel Belgium Nv | Methods and systems for improved bioavailability of active pharmaceutical ingredients including esomeprazole |
| KR101706725B1 (ko) * | 2015-06-12 | 2017-02-16 | 주식회사 세종파마텍 | 정제 코팅 스프레이건 어셈블리 |
| CN106619128B (zh) * | 2015-11-04 | 2019-12-06 | 曹荣华 | 胶囊的封存组合物及其封存方法 |
| EP3167867A1 (en) * | 2015-11-16 | 2017-05-17 | Capsugel Belgium NV | Tamperproof dosage form |
| EP3167870B1 (en) * | 2015-11-16 | 2024-01-03 | Capsugel Belgium NV | Tamperproof oral dosage form |
| EP3167868A1 (en) * | 2015-11-16 | 2017-05-17 | Capsugel Belgium NV | Tamperproof dosage form |
| EP3167869B1 (en) * | 2015-11-16 | 2025-02-12 | Capsugel Belgium NV | Tamperproof oral dosage form |
| EP3199148B1 (en) | 2016-01-28 | 2020-12-02 | Capsugel Belgium NV | Compositions and resulting hard capsules comprising hydrophilic coloring foodstuff concentrates |
| EP3219300B1 (en) | 2016-03-15 | 2019-06-19 | Capsugel Belgium NV | Aseptic hard capsule sealing apparatus and methods |
| EP3272340A1 (en) | 2016-07-22 | 2018-01-24 | Capsugel Belgium NV | Acid resistant capsules |
| IL266695B (en) * | 2016-12-08 | 2022-09-01 | Scherer Technologies Llc R P | A method of damping stress in capsule shells to reduce the tendency to break |
| CA3059527A1 (en) | 2017-04-14 | 2018-10-18 | Capsugel Belgium Nv | Pullulan capsules |
| CN107157949B (zh) * | 2017-06-09 | 2021-01-15 | 厦门普罗康客科技有限公司 | 硬胶囊内部封口的方法及其应用 |
| EP3607931B1 (de) * | 2018-08-07 | 2023-03-29 | Harro Höfliger Verpackungsmaschinen GmbH | Kapselverschliesseinrichtung zum verschliessen zweiteiliger kapseln |
| WO2020230151A1 (en) * | 2019-05-15 | 2020-11-19 | Scitech Centre | Capsule sealing system and method therefor |
| EP4196073B1 (en) | 2020-10-02 | 2023-11-29 | Capsugel Belgium NV | Device for dispensing single droplets into a cap or body of a capsule |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB617723A (en) * | 1945-10-31 | 1949-02-10 | Alfonso Mario Donofrio | Capsules and methods of manufacturing them |
| US2738827A (en) * | 1953-06-23 | 1956-03-20 | Edward R Dayton | Capsule sealing and marking apparatus |
| US3071513A (en) * | 1959-11-23 | 1963-01-01 | Upjohn Co | Process for sealing capsules |
| NL256671A (enExample) * | 1960-10-08 | 1965-02-15 | ||
| US3164508A (en) * | 1961-10-19 | 1965-01-05 | Ncr Co | Method for bonding plastic materials of the thermoplastic type |
| US3073087A (en) * | 1962-01-25 | 1963-01-15 | American Cyanamid Co | Method of sealing hard shell capsules |
| US3159546A (en) * | 1962-10-12 | 1964-12-01 | F G Okie Inc | Capsule sealing composition |
| US3394983A (en) * | 1963-06-14 | 1968-07-30 | American Cyanamid Co | Dip-dyeing capsules |
| US3466842A (en) * | 1967-05-10 | 1969-09-16 | Smithkline Corp | Machine for treating capsules |
| BE792903A (nl) * | 1971-12-30 | 1973-06-18 | American Can Co | Laserstraal-lassen van kunststoffen buizen |
| US3727022A (en) * | 1972-07-17 | 1973-04-10 | Procter & Gamble | Electromagnetic heating and sealing |
| GB1478759A (en) * | 1974-11-18 | 1977-07-06 | Alza Corp | Process for forming outlet passageways in pills using a laser |
| JPS5459312A (en) * | 1977-10-13 | 1979-05-12 | Chukyo Electric Co | Closing of hard capsule |
| US4281763A (en) * | 1979-10-31 | 1981-08-04 | Pace Joseph A | Two-piece hardshell, soluble and digestible liquid containing gelatin capsule |
-
1983
- 1983-02-18 US US06/468,022 patent/US4539060A/en not_active Ceased
- 1983-09-13 EP EP83305330A patent/EP0116743B1/en not_active Expired
- 1983-09-13 AT AT83305330T patent/ATE33346T1/de not_active IP Right Cessation
- 1983-09-13 DE DE8383305330T patent/DE3376197D1/de not_active Expired
- 1983-09-15 IN IN639/DEL/83A patent/IN160442B/en unknown
- 1983-09-29 AU AU19773/83A patent/AU559678B2/en not_active Ceased
- 1983-10-04 ES ES526230A patent/ES8501976A1/es not_active Expired
- 1983-10-11 CA CA000438716A patent/CA1255271A/en not_active Expired
- 1983-10-14 KR KR1019830004869A patent/KR890000206B1/ko not_active Expired
- 1983-10-17 SU SU833655358A patent/SU1393309A3/ru active
- 1983-10-27 JP JP58200103A patent/JPS59156349A/ja active Granted
- 1983-11-04 YU YU2195/83A patent/YU44447B/xx unknown
- 1983-11-11 BR BR8306208A patent/BR8306208A/pt not_active IP Right Cessation
- 1983-11-28 PH PH29897A patent/PH20191A/en unknown
- 1983-11-30 IE IE2820/83A patent/IE56363B1/en not_active IP Right Cessation
Non-Patent Citations (1)
| Title |
|---|
| Патент US № 3071513,кл.421-14, опублик. 1959. * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2404735C2 (ru) * | 2006-08-04 | 2010-11-27 | Пфайзер Продактс Инк. | Способ и устройство для герметизации капсул |
| US8181425B2 (en) | 2006-08-04 | 2012-05-22 | Capsugel Belgium | Apparatus for sealing capsules |
Also Published As
| Publication number | Publication date |
|---|---|
| YU44447B (en) | 1990-08-31 |
| PH20191A (en) | 1986-10-16 |
| CA1255271A (en) | 1989-06-06 |
| YU219583A (en) | 1986-02-28 |
| DE3376197D1 (en) | 1988-05-11 |
| EP0116743B1 (en) | 1988-04-06 |
| AU1977383A (en) | 1984-08-23 |
| IE56363B1 (en) | 1991-07-03 |
| BR8306208A (pt) | 1984-11-13 |
| KR840007664A (ko) | 1984-12-20 |
| JPH0140627B2 (enExample) | 1989-08-30 |
| US4539060A (en) | 1985-09-03 |
| IE832820L (en) | 1984-08-18 |
| ES526230A0 (es) | 1984-12-16 |
| ES8501976A1 (es) | 1984-12-16 |
| ATE33346T1 (de) | 1988-04-15 |
| AU559678B2 (en) | 1987-03-19 |
| JPS59156349A (ja) | 1984-09-05 |
| EP0116743A1 (en) | 1984-08-29 |
| IN160442B (enExample) | 1987-07-11 |
| KR890000206B1 (ko) | 1989-03-10 |
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