SMT201700145T1 - Composti anestetici e relativi procedimenti di utilizzo - Google Patents
Composti anestetici e relativi procedimenti di utilizzoInfo
- Publication number
- SMT201700145T1 SMT201700145T1 SM20170145T SMT201700145T SMT201700145T1 SM T201700145 T1 SMT201700145 T1 SM T201700145T1 SM 20170145 T SM20170145 T SM 20170145T SM T201700145 T SMT201700145 T SM T201700145T SM T201700145 T1 SMT201700145 T1 SM T201700145T1
- Authority
- SM
- San Marino
- Prior art keywords
- related methods
- anesthetic compounds
- anesthetic
- compounds
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261586450P | 2012-01-13 | 2012-01-13 | |
| US201261622627P | 2012-04-11 | 2012-04-11 | |
| EP13735638.2A EP2802325B1 (en) | 2012-01-13 | 2013-01-11 | Anesthetic compounds and related methods of use |
| PCT/US2013/021245 WO2013106717A1 (en) | 2012-01-13 | 2013-01-11 | Anesthetic compounds and related methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SMT201700145T1 true SMT201700145T1 (it) | 2017-05-08 |
Family
ID=48781947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM20170145T SMT201700145T1 (it) | 2012-01-13 | 2013-01-11 | Composti anestetici e relativi procedimenti di utilizzo |
Country Status (24)
| Country | Link |
|---|---|
| US (4) | US9156825B2 (OSRAM) |
| EP (2) | EP3184512B1 (OSRAM) |
| JP (1) | JP6196986B2 (OSRAM) |
| CN (2) | CN104168899B (OSRAM) |
| AU (1) | AU2013207811B2 (OSRAM) |
| BR (1) | BR112014017230A2 (OSRAM) |
| CA (1) | CA2861071C (OSRAM) |
| CY (1) | CY1118842T1 (OSRAM) |
| DK (1) | DK2802325T3 (OSRAM) |
| EA (1) | EA027976B1 (OSRAM) |
| ES (1) | ES2617536T3 (OSRAM) |
| HR (1) | HRP20170330T1 (OSRAM) |
| HU (1) | HUE030892T2 (OSRAM) |
| IN (1) | IN2014DN06132A (OSRAM) |
| LT (1) | LT2802325T (OSRAM) |
| NZ (1) | NZ627274A (OSRAM) |
| PL (1) | PL2802325T3 (OSRAM) |
| PT (1) | PT2802325T (OSRAM) |
| RS (1) | RS56025B1 (OSRAM) |
| SG (1) | SG11201403980VA (OSRAM) |
| SI (1) | SI2802325T1 (OSRAM) |
| SM (1) | SMT201700145T1 (OSRAM) |
| WO (1) | WO2013106717A1 (OSRAM) |
| ZA (1) | ZA201405248B (OSRAM) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3360863T3 (pl) * | 2015-10-10 | 2022-08-08 | Jiangsu Nhwaluokang Pharmaceutical Research And Development Co., Ltd. | Pochodna i związek pośredni etomidatu, sposób przygotowania i zastosowanie |
| CN105663042A (zh) * | 2016-02-03 | 2016-06-15 | 北京蓝丹医药科技有限公司 | 一种稳定的麻醉药物脂肪乳及其制备方法 |
| CN107382870A (zh) * | 2016-05-17 | 2017-11-24 | 四川海思科制药有限公司 | N‑取代咪唑羧酸酯类化合物及其制备方法和在医药上的用途 |
| CN107445898A (zh) * | 2016-05-30 | 2017-12-08 | 四川海思科制药有限公司 | N‑取代咪唑羧酸酯类化合物及其制备方法和在医药上的用途 |
| CN107522662A (zh) * | 2016-06-16 | 2017-12-29 | 四川海思科制药有限公司 | N‑取代咪唑羧酸酯类化合物及其制备方法和在医药上的用途 |
| CN107641105A (zh) * | 2016-07-22 | 2018-01-30 | 四川海思科制药有限公司 | N‑取代咪唑羧酸酯类化合物及其制备方法和在医药上的用途 |
| CN106432163A (zh) * | 2016-09-29 | 2017-02-22 | 山东东方农药科技实业有限公司 | 一种螺环内酯类化合物、其合成方法以及其用途 |
| CN107652239B (zh) * | 2017-02-24 | 2020-08-04 | 四川大学华西医院 | N-取代咪唑羧酸酯类化合物、制备方法及用途 |
| CN109776511B (zh) * | 2018-01-30 | 2023-10-27 | 成都麻沸散医药科技有限公司 | 一种n-取代咪唑甲酸酯类衍生物及其用途 |
| CN109053410A (zh) * | 2018-08-06 | 2018-12-21 | 兰博尔开封科技有限公司 | 一种合成1-羟基环己基甲酸的新工艺及应用 |
| CN118806924A (zh) | 2018-09-26 | 2024-10-22 | 江苏恒瑞医药股份有限公司 | 依喜替康类似物的配体-药物偶联物及其制备方法和应用 |
| CN112543771B (zh) | 2018-09-30 | 2023-04-11 | 江苏豪森药业集团有限公司 | 抗b7h3抗体-依喜替康类似物偶联物及其医药用途 |
| CN109761906B (zh) * | 2019-03-02 | 2023-08-11 | 成都麻沸散医药科技有限公司 | 一种取代咪唑甲酸酯类衍生物及其用途 |
| CN110003188B (zh) * | 2019-03-27 | 2022-08-26 | 成都麻沸散医药科技有限公司 | 取代吡咯甲酸酯类衍生物及其用途 |
| AU2020347715A1 (en) | 2019-09-18 | 2022-04-07 | Systimmune, Inc. | Camptothecin derivative and conjugate thereof |
| CN110669017B (zh) * | 2019-10-11 | 2023-08-04 | 成都麻沸散医药科技有限公司 | 多取代三唑甲酸酯类衍生物及其用途 |
| CN112174890B (zh) * | 2020-10-09 | 2022-05-27 | 成都麻沸散医药科技有限公司 | 酮取代杂环化合物及其麻醉作用 |
| WO2021068943A1 (zh) * | 2019-10-11 | 2021-04-15 | 成都麻沸散医药科技有限公司 | 一种取代氮杂环化合物及其麻醉作用 |
| CN114650845B (zh) | 2019-12-12 | 2024-04-16 | 江苏恒瑞医药股份有限公司 | 抗密蛋白抗体药物偶联物及其医药用途 |
| CN114729035B (zh) | 2019-12-16 | 2024-04-16 | 江苏恒瑞医药股份有限公司 | 抗cea抗体-依喜替康类似物偶联物及其医药用途 |
| EP4095148A4 (en) | 2020-01-22 | 2023-07-26 | Jiangsu Hengrui Medicine Co., Ltd. | EXATECAN ANTI-TOO-2-ANALOG ANTIBODY CONJUGATE AND ITS MEDICAL USE |
| AU2021210079A1 (en) | 2020-01-22 | 2022-08-25 | Jiangsu Hengrui Medicine Co., Ltd. | Drug conjugate of Eribulin derivative, preparation method therefor and application thereof in medicine |
| BR112022019073A2 (pt) | 2020-03-25 | 2022-11-08 | Jiangsu Hengrui Pharmaceuticals Co Ltd | Composição farmacêutica que compreende conjugado anticorpo-fármaco e uso da mesma |
| WO2021190583A1 (zh) | 2020-03-25 | 2021-09-30 | 江苏恒瑞医药股份有限公司 | 抗psma抗体-依喜替康类似物偶联物及其医药用途 |
| MX2022011769A (es) | 2020-03-25 | 2022-10-18 | Jiangsu Hengrui Pharmaceuticals Co Ltd | Metodo de preparacion de medicamento de conjugado de anticuerpo. |
| TW202310878A (zh) | 2021-07-22 | 2023-03-16 | 大陸商上海森輝醫藥有限公司 | 艾日布林衍生物的藥物偶聯物 |
| KR20240125958A (ko) | 2021-12-23 | 2024-08-20 | 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 | 항-dll3 항체, 이의 항체-약물 접합체 및 이의 의약적 용도 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3354173A (en) | 1964-04-16 | 1967-11-21 | Janssen Pharmaceutica Nv | Imidazole carboxylates |
| US3270960A (en) | 1964-09-11 | 1966-09-06 | Sperry Rand Corp | Fluid sensor |
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| CA1066709A (en) | 1975-03-10 | 1979-11-20 | Walter A.M. Helsen | Preparation of loweralkyl imidazole carboxylates |
| US4038286A (en) | 1975-03-10 | 1977-07-26 | Janssen Pharmaceutica N.V. | Racemates and optical isomers of 1-(1-phenylethyl)-1h-imidazole-5-carboylic acid derivatives |
| GR64915B (en) | 1978-09-14 | 1980-06-09 | Janssen Pharmaceutica Nv | Improved etomidate-containing compositions |
| EP0277384A3 (en) | 1986-12-24 | 1990-05-23 | Janssen Pharmaceutica N.V. | 1h-imidazole-5-carboxylic acid derivatives |
| US4878940A (en) | 1987-04-02 | 1989-11-07 | Janssen Pharmaceutica N.V. | Herbicidal 1,5-substituted 1H-imidazoles |
| US5041554A (en) | 1989-01-31 | 1991-08-20 | Merrell Dow Pharmaceuticals Inc. | Novel aryl-or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds useful in treating interleukin-1 mediated conditions |
| AR245694A1 (es) | 1989-01-31 | 1994-02-28 | Merrell Dow Pharma | Procedimiento para la preparacion de nuevos derivados de acidos aril- o heteroaril-1-alquilpirrol-2-carboxilicos utiles como inhibidores de interleuquina-1 |
| US5019583A (en) | 1989-02-15 | 1991-05-28 | Glaxo Inc. | N-phenyl-N-(4-piperidinyl)amides useful as analgesics |
| US5242939A (en) * | 1990-09-28 | 1993-09-07 | Warner-Lambert Company | Anilide derivatives with angiotensin ii antagonist properties |
| JP3374922B2 (ja) | 1991-05-09 | 2003-02-10 | 日産化学工業株式会社 | 複素環式第３級アミンの製造方法 |
| JPH06345728A (ja) | 1993-06-11 | 1994-12-20 | Nissan Chem Ind Ltd | Ｎ−置換アゾール誘導体の製造方法 |
| US5466700A (en) | 1993-08-30 | 1995-11-14 | Glaxo Wellcome Inc. | Anesthetic use of N-phenyl-N-(4-piperidinyl)amides |
| US5756528A (en) | 1995-06-06 | 1998-05-26 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| US5997898A (en) | 1995-06-06 | 1999-12-07 | Imarx Pharmaceutical Corp. | Stabilized compositions of fluorinated amphiphiles for methods of therapeutic delivery |
| JP4334229B2 (ja) | 2001-03-20 | 2009-09-30 | サイデックス・ファーマシューティカルズ・インコーポレイテッド | プロポフォール及びスルホアルキルエーテルシクロデキストリン含有製剤 |
| EP1458386B1 (en) | 2001-12-27 | 2007-04-18 | Ortho-McNeil Pharmaceutical, Inc. | Aroyl pyrrole heteroeryl and methanols useful for treating a central nervous system disorder |
| US7189859B2 (en) | 2003-08-06 | 2007-03-13 | Ilse Zolle | Radiolabelled phenylethyl imidazole carboxylic acid ester derivatives |
| US20080206138A1 (en) | 2003-08-06 | 2008-08-28 | Ilse Zolle | Radiolabelled Phenylethyl Imidazole Carboxylic Acid Ester Derivatives |
| JP2008510726A (ja) | 2004-08-20 | 2008-04-10 | エントレメッド インコーポレイテッド | プロテイナーゼ活性化受容体アンタゴニストを含む組成物および方法 |
| US7592362B2 (en) * | 2006-01-19 | 2009-09-22 | Pfizer Limited | Substituted imidazoles |
| CA2636787A1 (en) | 2006-01-24 | 2007-08-02 | Nippon Zoki Pharmaceutical Co., Ltd | Novel histidine derivatives |
| EP2035393A2 (en) * | 2006-06-09 | 2009-03-18 | GE Healthcare Limited | Synthesis and evaluation of 18f-labelled alkyl-1-[(r)-1-phenylethyl]-1h-imidazole-5-carboxylate as a tracer for the quantification of beta-11-hydroxylase enzyme in the adrenal glands |
| WO2009014097A1 (ja) | 2007-07-23 | 2009-01-29 | Nippon Zoki Pharmaceutical Co., Ltd. | 新規ヒスチジン誘導体 |
| EP2271627A4 (en) * | 2008-03-31 | 2012-04-11 | Gen Hospital Corp | ETOMIDATE ANALOGUE WITH IMPROVED PHARMACOKINETIC AND PHARMACODDYNAMIC PROPERTIES |
| WO2011005969A2 (en) * | 2009-07-10 | 2011-01-13 | The General Hospital Corporation | Etomidate analogues that do not inhibit adrenocortical steroid synthesis |
-
2013
- 2013-01-11 EP EP16198942.1A patent/EP3184512B1/en active Active
- 2013-01-11 NZ NZ627274A patent/NZ627274A/en not_active IP Right Cessation
- 2013-01-11 AU AU2013207811A patent/AU2013207811B2/en active Active
- 2013-01-11 DK DK13735638.2T patent/DK2802325T3/en active
- 2013-01-11 CA CA2861071A patent/CA2861071C/en active Active
- 2013-01-11 EA EA201491362A patent/EA027976B1/ru not_active IP Right Cessation
- 2013-01-11 SM SM20170145T patent/SMT201700145T1/it unknown
- 2013-01-11 HU HUE13735638A patent/HUE030892T2/hu unknown
- 2013-01-11 US US14/371,651 patent/US9156825B2/en active Active
- 2013-01-11 EP EP13735638.2A patent/EP2802325B1/en active Active
- 2013-01-11 BR BR112014017230-7A patent/BR112014017230A2/pt not_active IP Right Cessation
- 2013-01-11 CN CN201380014062.1A patent/CN104168899B/zh active Active
- 2013-01-11 JP JP2014552332A patent/JP6196986B2/ja active Active
- 2013-01-11 CN CN201710140475.4A patent/CN107382812A/zh active Pending
- 2013-01-11 PT PT137356382T patent/PT2802325T/pt unknown
- 2013-01-11 HR HRP20170330TT patent/HRP20170330T1/hr unknown
- 2013-01-11 ES ES13735638.2T patent/ES2617536T3/es active Active
- 2013-01-11 RS RS20170208A patent/RS56025B1/sr unknown
- 2013-01-11 SI SI201330552A patent/SI2802325T1/sl unknown
- 2013-01-11 PL PL13735638T patent/PL2802325T3/pl unknown
- 2013-01-11 WO PCT/US2013/021245 patent/WO2013106717A1/en active Application Filing
- 2013-01-11 LT LTEP13735638.2T patent/LT2802325T/lt unknown
- 2013-01-11 IN IN6132DEN2014 patent/IN2014DN06132A/en unknown
- 2013-01-11 SG SG11201403980VA patent/SG11201403980VA/en unknown
-
2014
- 2014-07-17 ZA ZA2014/05248A patent/ZA201405248B/en unknown
-
2015
- 2015-07-24 US US14/808,413 patent/US9522136B2/en active Active
-
2016
- 2016-11-10 US US15/348,790 patent/US9820971B2/en active Active
-
2017
- 2017-02-24 CY CY20171100255T patent/CY1118842T1/el unknown
- 2017-10-19 US US15/788,351 patent/US10154991B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA201405248B (en) | Anesthetic compounds and related methods of use | |
| IL276761A (en) | Methods of inducing coma | |
| SG11201504049VA (en) | Compounds and their methods of use | |
| ZA201502503B (en) | Hppd variants and methods of use | |
| SG11201502343RA (en) | Cyclic ether pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use | |
| ZA201401653B (en) | Pyrazol-4yl-heterocyclyl-carboxamide compounds and methods of use | |
| ZA201308859B (en) | Quinazolines as therapeutic compounds and related methods of use | |
| EP2717898A4 (en) | PRO-COAGULANT COMPOUNDS AND METHODS OF USE | |
| IL222227A0 (en) | Pyrazol - 4 - heterocyclyl-carboxamide compounds and methods of use | |
| EP2879676A4 (en) | SUBSTITUTED PYRAZOLONE COMPOUNDS AND METHODS OF USE | |
| PL2833884T3 (pl) | Zastosowanie inhibitorów ccr3 | |
| EP2709999A4 (en) | QUINAZOLINE-7-ETHER COMPOUNDS AND METHODS OF USE | |
| ZA201408128B (en) | Etract of greyia radlkoferi and use thereof | |
| GB201216381D0 (en) | New compounds and medical uses | |
| GB201208970D0 (en) | New compounds and medical uses |