SMT201600071B - Derivato di acido pirrolidina-3-ilacetico - Google Patents
Derivato di acido pirrolidina-3-ilaceticoInfo
- Publication number
- SMT201600071B SMT201600071B SM201600071T SM201600071T SMT201600071B SM T201600071 B SMT201600071 B SM T201600071B SM 201600071 T SM201600071 T SM 201600071T SM 201600071 T SM201600071 T SM 201600071T SM T201600071 B SMT201600071 B SM T201600071B
- Authority
- SM
- San Marino
- Prior art keywords
- pyrrolidine
- acid derivative
- ilacetic
- ilacetic acid
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011199482 | 2011-09-13 | ||
| PCT/JP2012/073171 WO2013039057A1 (ja) | 2011-09-13 | 2012-09-11 | ピロリジン－３－イル酢酸誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SMT201600071B true SMT201600071B (it) | 2016-04-29 |
Family
ID=47883287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM201600071T SMT201600071B (it) | 2011-09-13 | 2016-03-10 | Derivato di acido pirrolidina-3-ilacetico |
Country Status (32)
| Country | Link |
|---|---|
| EP (1) | EP2757103B1 (ar) |
| JP (1) | JP5829689B2 (ar) |
| KR (1) | KR101963922B1 (ar) |
| CN (1) | CN103764648B (ar) |
| AR (1) | AR087788A1 (ar) |
| AU (1) | AU2012309556B2 (ar) |
| BR (1) | BR112014004267B1 (ar) |
| CA (1) | CA2844617C (ar) |
| CL (1) | CL2014000484A1 (ar) |
| CY (1) | CY1117460T1 (ar) |
| DK (1) | DK2757103T3 (ar) |
| ES (1) | ES2564732T3 (ar) |
| HK (1) | HK1193407A1 (ar) |
| HR (1) | HRP20160166T1 (ar) |
| HU (1) | HUE026824T2 (ar) |
| IL (1) | IL230804A (ar) |
| JO (1) | JO3082B1 (ar) |
| ME (1) | ME02383B (ar) |
| MX (1) | MX358494B (ar) |
| MY (1) | MY169869A (ar) |
| PE (1) | PE20141353A1 (ar) |
| PL (1) | PL2757103T3 (ar) |
| PT (1) | PT2757103E (ar) |
| RS (1) | RS54582B1 (ar) |
| RU (1) | RU2615135C2 (ar) |
| SG (1) | SG11201400163WA (ar) |
| SI (1) | SI2757103T1 (ar) |
| SM (1) | SMT201600071B (ar) |
| TW (1) | TWI543975B (ar) |
| UA (1) | UA112873C2 (ar) |
| WO (1) | WO2013039057A1 (ar) |
| ZA (1) | ZA201400918B (ar) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2642805T3 (es) * | 2013-03-12 | 2017-11-20 | Eisai R&D Management Co., Ltd. | Sal de un derivado del ácido pirrolidín-3-ilacético y cristales de esta |
| WO2014142086A1 (ja) * | 2013-03-13 | 2014-09-18 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ピロリジン－３－イル酢酸誘導体およびピペリジン－３－イル酢酸誘導体 |
| WO2024083933A1 (en) | 2022-10-19 | 2024-04-25 | Astrazeneca Ab | 2,4,6-trisubstituted 1,3,5-triazines as modulators of cx 3cr1 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4263391B2 (ja) | 2001-03-19 | 2009-05-13 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 抗ｃｘ３ｃｒ１抗体、抗フラクタルカイン抗体及びフラクタルカインの利用 |
| US20050143372A1 (en) * | 2001-10-30 | 2005-06-30 | Shomir Ghosh | Compounds, pharmaceutical compositions and methods of use therefor |
| KR20060120014A (ko) * | 2003-10-07 | 2006-11-24 | 아스트라제네카 아베 | 케모킨, 특히 ｃｘ3ｃｒ1 수용체 길항제로서 유용한 신규한2-치환된 4-아미노-티아졸로[4,5-ｄ]피리미딘 |
| AR053347A1 (es) * | 2005-04-06 | 2007-05-02 | Astrazeneca Ab | Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos |
| UA90707C2 (en) | 2005-04-06 | 2010-05-25 | Астразенека Аб | Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives |
| CN101522693B (zh) | 2006-09-29 | 2012-01-04 | 阿斯利康(瑞典)有限公司 | 5，7-二取代的[1，3]噻唑并[4，5-d]嘧啶-2(3h)-胺衍生物和它们在治疗中的用途 |
| TW200820973A (en) | 2006-09-29 | 2008-05-16 | Astrazeneca Ab | Novel compounds 480 |
| CL2007002958A1 (es) * | 2006-10-12 | 2008-05-09 | Epix Delaware Inc | Compuestos derivados de heteroaril-carboxamida, antagonistas del receptor de quimioquina; composicion farmaceutica; y uso para el tratamiento o prevencion de enfermedades tales como rechazo de transplante de organos, artritis reumatoidea, lupus, entr |
| SI2262777T1 (sl) * | 2008-03-07 | 2016-05-31 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | 1-benzil-3-hidroksimetilindazolni derivati in njihova uporaba pri zdravljenju bolezni, ki temeljijo na ekspresiji MCP-1 in CX3CR1 |
| AR071036A1 (es) | 2008-03-26 | 2010-05-19 | Astrazeneca Ab | Derivados 5, 7-disustituidos de [1, 3]tiazolo[4, 5-d]pirimidin-2 (3h)-ona, una composicion farmaceutica que los comprende y su uso en el tratamiento de enfermedades mediadas por el receptor cx3cr1. |
-
2012
- 2012-09-05 TW TW101132401A patent/TWI543975B/zh not_active IP Right Cessation
- 2012-09-05 JO JOP/2012/0251A patent/JO3082B1/ar active
- 2012-09-06 AR ARP120103280A patent/AR087788A1/es active IP Right Grant
- 2012-09-11 SG SG11201400163WA patent/SG11201400163WA/en unknown
- 2012-09-11 CN CN201280041634.0A patent/CN103764648B/zh not_active Expired - Fee Related
- 2012-09-11 AU AU2012309556A patent/AU2012309556B2/en not_active Ceased
- 2012-09-11 PE PE2014000266A patent/PE20141353A1/es active IP Right Grant
- 2012-09-11 MX MX2014002210A patent/MX358494B/es active IP Right Grant
- 2012-09-11 MY MYPI2014700213A patent/MY169869A/en unknown
- 2012-09-11 ES ES12831085.1T patent/ES2564732T3/es active Active
- 2012-09-11 SI SI201230463T patent/SI2757103T1/sl unknown
- 2012-09-11 DK DK12831085.1T patent/DK2757103T3/en active
- 2012-09-11 CA CA2844617A patent/CA2844617C/en active Active
- 2012-09-11 JP JP2013533669A patent/JP5829689B2/ja not_active Expired - Fee Related
- 2012-09-11 BR BR112014004267-5A patent/BR112014004267B1/pt not_active IP Right Cessation
- 2012-09-11 PL PL12831085T patent/PL2757103T3/pl unknown
- 2012-09-11 HU HUE12831085A patent/HUE026824T2/en unknown
- 2012-09-11 KR KR1020147003630A patent/KR101963922B1/ko active IP Right Grant
- 2012-09-11 ME MEP-2016-37A patent/ME02383B/me unknown
- 2012-09-11 RU RU2014107536A patent/RU2615135C2/ru active
- 2012-09-11 RS RS20160106A patent/RS54582B1/en unknown
- 2012-09-11 PT PT128310851T patent/PT2757103E/pt unknown
- 2012-09-11 WO PCT/JP2012/073171 patent/WO2013039057A1/ja active Application Filing
- 2012-09-11 EP EP12831085.1A patent/EP2757103B1/en active Active
- 2012-11-09 UA UAA201401661A patent/UA112873C2/uk unknown
-
2014
- 2014-02-03 IL IL230804A patent/IL230804A/en active IP Right Grant
- 2014-02-06 ZA ZA2014/00918A patent/ZA201400918B/en unknown
- 2014-02-27 CL CL2014000484A patent/CL2014000484A1/es unknown
- 2014-07-04 HK HK14106800.1A patent/HK1193407A1/xx not_active IP Right Cessation
-
2016
- 2016-02-16 HR HRP20160166TT patent/HRP20160166T1/hr unknown
- 2016-03-10 SM SM201600071T patent/SMT201600071B/xx unknown
- 2016-03-16 CY CY20161100224T patent/CY1117460T1/el unknown
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