SMT201400065B - Liposomi idrolizzabili da spla2 con una miglioratastabilita'di conservazione - Google Patents

Liposomi idrolizzabili da spla2 con una miglioratastabilita'di conservazione

Info

Publication number
SMT201400065B
SMT201400065B SM201400065T SM201400065T SMT201400065B SM T201400065 B SMT201400065 B SM T201400065B SM 201400065 T SM201400065 T SM 201400065T SM 201400065 T SM201400065 T SM 201400065T SM T201400065 B SMT201400065 B SM T201400065B
Authority
SM
San Marino
Prior art keywords
spla2
storage stability
improved storage
hydrolysable liposomes
hydrolysable
Prior art date
Application number
SM201400065T
Other languages
English (en)
Italian (it)
Inventor
Mogens Winkel Madsen
Sune Allan Petersen
Anders Falk Vikbjerg
Original Assignee
Bio Bedst Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Bedst Aps filed Critical Bio Bedst Aps
Publication of SMT201400065B publication Critical patent/SMT201400065B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SM201400065T 2009-10-23 2014-06-05 Liposomi idrolizzabili da spla2 con una miglioratastabilita'di conservazione SMT201400065B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200901150A DK177529B1 (en) 2009-10-23 2009-10-23 Liposomes with improved storage stability
PCT/DK2010/050283 WO2011047689A2 (en) 2009-10-23 2010-10-25 Liposomes with improved storage stability

Publications (1)

Publication Number Publication Date
SMT201400065B true SMT201400065B (it) 2014-07-07

Family

ID=43533079

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201400065T SMT201400065B (it) 2009-10-23 2014-06-05 Liposomi idrolizzabili da spla2 con una miglioratastabilita'di conservazione

Country Status (16)

Country Link
US (1) US9820941B2 (enExample)
EP (1) EP2490671B1 (enExample)
JP (1) JP5778160B2 (enExample)
CN (1) CN102639114B (enExample)
AU (1) AU2010310240B2 (enExample)
CA (1) CA2772973C (enExample)
CY (1) CY1115139T1 (enExample)
DK (2) DK177529B1 (enExample)
ES (1) ES2465565T3 (enExample)
HR (1) HRP20140413T1 (enExample)
PL (1) PL2490671T3 (enExample)
PT (1) PT2490671E (enExample)
RS (1) RS53321B (enExample)
SI (1) SI2490671T1 (enExample)
SM (1) SMT201400065B (enExample)
WO (1) WO2011047689A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2123258A1 (en) 2008-05-23 2009-11-25 Liplasome Pharma A/S Liposomes for drug delivery
DK177532B1 (en) 2009-09-17 2013-09-08 Bio Bedst Aps Medical use of sPLA2 hydrolysable liposomes
EP2394640A1 (en) 2010-05-21 2011-12-14 MediGene AG Improved liposomal formulations of lipophilic compounds
WO2015166987A1 (ja) * 2014-04-30 2015-11-05 富士フイルム株式会社 リポソーム組成物及びその製造方法
JP6263609B2 (ja) * 2014-04-30 2018-01-17 富士フイルム株式会社 リポソーム組成物及びその製造方法
EP3138555B1 (en) 2014-04-30 2020-10-28 FUJIFILM Corporation Liposome composition and production method therefor
JP6715265B2 (ja) * 2015-05-04 2020-07-01 フェルザンティス アーゲーVersantis Ag 膜内外pH勾配ベシクルを調製する方法
US9725769B1 (en) 2016-10-07 2017-08-08 Oncology Venture ApS Methods for predicting drug responsiveness in cancer patients
AU2017258901A1 (en) 2016-12-30 2018-07-19 Allarity Therapeutics Europe ApS Methods for predicting drug responsiveness in cancer patients
AU2019200325A1 (en) * 2018-01-31 2019-08-15 Liplasome Pharma Aps Methods for treating cancer and predicting drug responsiveness in cancer patients
CN110496103B (zh) * 2018-05-18 2022-05-10 上海维洱生物医药科技有限公司 一种多西他赛棕榈酸酯脂质体及其制备方法
DK3811949T3 (da) 2018-06-20 2024-10-07 Fujifilm Corp Kombineret medicin omfattende gemcitabin-indkapslet liposomsammensætning og immun-checkpoint-blokade

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
CA1335348C (en) 1988-03-04 1995-04-25 Yasuaki Ogawa Liposome composition
JP2931981B2 (ja) * 1988-03-04 1999-08-09 武田薬品工業株式会社 リポソーム製剤およびその製造法
FI895340A7 (fi) * 1988-11-14 1990-05-15 Bristol Myers Squibb Co Hypertoninen cisplatin-liuos
JPH05194192A (ja) * 1991-08-21 1993-08-03 Shionogi & Co Ltd 分散性の改善された温度感受性mlv型リポソ−ム
JPH069374A (ja) * 1992-04-07 1994-01-18 Banyu Pharmaceut Co Ltd リポソ−ム製剤およびその製造法
US6027726A (en) 1994-09-30 2000-02-22 Inex Phamaceuticals Corp. Glycosylated protein-liposome conjugates and methods for their preparation
US5858397A (en) 1995-10-11 1999-01-12 University Of British Columbia Liposomal formulations of mitoxantrone
PT929293E (pt) * 1996-08-23 2004-03-31 Sequus Pharm Inc Lipossomas contendo um composto de cisplatina
FR2759293B1 (fr) * 1997-02-11 1999-04-30 Ethypharm Lab Prod Ethiques Microgranules contenant du cisplatine, procede de fabrication, preparation pharmaceutique et utilisation en polychimiotherapie ou en association avec une radiotherapie
AU778659B2 (en) 2000-02-10 2004-12-16 Liplasome Pharma A/S Lipid-based drug delivery systems
AU2001248302A1 (en) * 2000-04-12 2001-10-23 Liplasome Pharma A/S Lipid-based drug delivery systems against parasitic infections
US20030026831A1 (en) 2001-04-20 2003-02-06 Aparna Lakkaraju Anionic liposomes for delivery of bioactive agents
CA2383259A1 (en) 2002-04-23 2003-10-23 Celator Technologies Inc. Synergistic compositions
US20050118250A1 (en) 2001-11-13 2005-06-02 Paul Tardi Lipid carrier compositions with enhanced blood stability
US20040022842A1 (en) 2002-06-03 2004-02-05 Mebiopharm Co., Ltd. Liposome preparations containing oxaliplatin
EP1643971A2 (en) 2003-05-22 2006-04-12 Neopharm, Inc. Liposomal formulations comprising a combination of two or more active agents
GB0312309D0 (en) * 2003-05-29 2003-07-02 Gaslini Children S Hospital G Targeted liposome
WO2006025411A1 (ja) 2004-08-31 2006-03-09 Astellas Pharm. Inc. 細胞内薬物送達改善リポソーム
WO2006048017A1 (en) 2004-11-03 2006-05-11 Liplasome Pharma A/S Lipid-based drug delivery systems containing unnatural phospholipase a2 degradable lipid derivatives and the therapeutic uses thereof
US20070014845A1 (en) * 2005-07-01 2007-01-18 Yuanpeng Zhang Liposomal delivery vehicle for hydrophobic drugs
CN101040853B (zh) * 2006-03-22 2010-05-12 上海医药工业研究院 一种草乌甲素多泡脂质体及其制备方法
EP2004236A2 (en) 2006-03-23 2008-12-24 Liplasome Pharma A/S Lipid based drug delivery systems comprising phospholipase a2 degradable lipids that perform an intramolecular cyclization reaction upon hydrolysis
US20080085295A1 (en) 2006-07-14 2008-04-10 Fmc Biopolymer As Hydrogels containing low molecular weight alginates and biostructures made therefrom
CN100563646C (zh) * 2007-07-13 2009-12-02 陈祥峰 一种奥沙利铂脂质体葡萄糖制剂的制备方法
EP2123258A1 (en) * 2008-05-23 2009-11-25 Liplasome Pharma A/S Liposomes for drug delivery

Also Published As

Publication number Publication date
PT2490671E (pt) 2014-05-30
CA2772973C (en) 2017-08-15
CN102639114B (zh) 2015-04-01
CA2772973A1 (en) 2011-04-28
RS53321B (sr) 2014-10-31
AU2010310240B2 (en) 2015-11-26
JP2013508315A (ja) 2013-03-07
JP5778160B2 (ja) 2015-09-16
US9820941B2 (en) 2017-11-21
PL2490671T3 (pl) 2014-08-29
DK200901150A (en) 2011-04-24
DK2490671T3 (da) 2014-06-16
US20120219618A1 (en) 2012-08-30
WO2011047689A2 (en) 2011-04-28
WO2011047689A3 (en) 2011-11-17
AU2010310240A1 (en) 2012-03-22
ES2465565T3 (es) 2014-06-06
HRP20140413T1 (hr) 2014-07-04
CN102639114A (zh) 2012-08-15
CY1115139T1 (el) 2016-12-14
DK177529B1 (en) 2013-09-08
SI2490671T1 (sl) 2014-07-31
EP2490671A2 (en) 2012-08-29
EP2490671B1 (en) 2014-03-05

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