SI2490671T1 - Liposomi, ki jih je mogoče hidrolizirati sPLA2 in imajo izboljšano stabilnost pri shranjevanju - Google Patents

Liposomi, ki jih je mogoče hidrolizirati sPLA2 in imajo izboljšano stabilnost pri shranjevanju

Info

Publication number
SI2490671T1
SI2490671T1 SI201030638T SI201030638T SI2490671T1 SI 2490671 T1 SI2490671 T1 SI 2490671T1 SI 201030638 T SI201030638 T SI 201030638T SI 201030638 T SI201030638 T SI 201030638T SI 2490671 T1 SI2490671 T1 SI 2490671T1
Authority
SI
Slovenia
Prior art keywords
storag
stability
improved
spla2 hydrolysable
hydrolysable liposomes
Prior art date
Application number
SI201030638T
Other languages
English (en)
Slovenian (sl)
Inventor
Mogens Winkel Madsen
Sune Allan Petersen
Anders Falk Vikbjerg
Original Assignee
Bio-Bedst Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio-Bedst Aps filed Critical Bio-Bedst Aps
Publication of SI2490671T1 publication Critical patent/SI2490671T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI201030638T 2009-10-23 2010-10-25 Liposomi, ki jih je mogoče hidrolizirati sPLA2 in imajo izboljšano stabilnost pri shranjevanju SI2490671T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200901150A DK177529B1 (en) 2009-10-23 2009-10-23 Liposomes with improved storage stability
PCT/DK2010/050283 WO2011047689A2 (en) 2009-10-23 2010-10-25 Liposomes with improved storage stability
EP10772956.8A EP2490671B1 (en) 2009-10-23 2010-10-25 Spla2 hydrolysable liposomes with improved storag stability

Publications (1)

Publication Number Publication Date
SI2490671T1 true SI2490671T1 (sl) 2014-07-31

Family

ID=43533079

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201030638T SI2490671T1 (sl) 2009-10-23 2010-10-25 Liposomi, ki jih je mogoče hidrolizirati sPLA2 in imajo izboljšano stabilnost pri shranjevanju

Country Status (16)

Country Link
US (1) US9820941B2 (enExample)
EP (1) EP2490671B1 (enExample)
JP (1) JP5778160B2 (enExample)
CN (1) CN102639114B (enExample)
AU (1) AU2010310240B2 (enExample)
CA (1) CA2772973C (enExample)
CY (1) CY1115139T1 (enExample)
DK (2) DK177529B1 (enExample)
ES (1) ES2465565T3 (enExample)
HR (1) HRP20140413T1 (enExample)
PL (1) PL2490671T3 (enExample)
PT (1) PT2490671E (enExample)
RS (1) RS53321B (enExample)
SI (1) SI2490671T1 (enExample)
SM (1) SMT201400065B (enExample)
WO (1) WO2011047689A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2123258A1 (en) 2008-05-23 2009-11-25 Liplasome Pharma A/S Liposomes for drug delivery
DK177532B1 (en) 2009-09-17 2013-09-08 Bio Bedst Aps Medical use of sPLA2 hydrolysable liposomes
EP2394640A1 (en) 2010-05-21 2011-12-14 MediGene AG Improved liposomal formulations of lipophilic compounds
JP6251385B2 (ja) * 2014-04-30 2017-12-20 富士フイルム株式会社 リポソーム組成物及びその製造方法
WO2015166985A1 (ja) * 2014-04-30 2015-11-05 富士フイルム株式会社 リポソーム組成物及びその製造方法
JP6276847B2 (ja) * 2014-04-30 2018-02-07 富士フイルム株式会社 リポソーム組成物及びその製造方法
WO2016177741A1 (en) 2015-05-04 2016-11-10 Eth Zurich Method for preparing transmembrane ph-gradient vesicles
US9725769B1 (en) 2016-10-07 2017-08-08 Oncology Venture ApS Methods for predicting drug responsiveness in cancer patients
AU2017258901A1 (en) 2016-12-30 2018-07-19 Allarity Therapeutics Europe ApS Methods for predicting drug responsiveness in cancer patients
AU2019200325A1 (en) * 2018-01-31 2019-08-15 Liplasome Pharma Aps Methods for treating cancer and predicting drug responsiveness in cancer patients
CN110496103B (zh) * 2018-05-18 2022-05-10 上海维洱生物医药科技有限公司 一种多西他赛棕榈酸酯脂质体及其制备方法
TWI892261B (zh) 2018-06-20 2025-08-01 日商富士軟片股份有限公司 包含內含吉西他濱之脂質體組成物及免疫檢查點抑制劑之組合醫藥

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US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
DE68901733T2 (de) 1988-03-04 1993-03-25 Takeda Chemical Industries Ltd Liposom-zusammensetzung.
JP2931981B2 (ja) * 1988-03-04 1999-08-09 武田薬品工業株式会社 リポソーム製剤およびその製造法
FI895340A7 (fi) * 1988-11-14 1990-05-15 Bristol Myers Squibb Co Hypertoninen cisplatin-liuos
JPH05194192A (ja) * 1991-08-21 1993-08-03 Shionogi & Co Ltd 分散性の改善された温度感受性ｍｌｖ型リポソ−ム
JPH069374A (ja) * 1992-04-07 1994-01-18 Banyu Pharmaceut Co Ltd リポソ−ム製剤およびその製造法
WO1996010585A1 (en) 1994-09-30 1996-04-11 Inex Pharmaceuticals Corp. Glycosylated protein-liposome conjugates and methods for their preparation
US5858397A (en) 1995-10-11 1999-01-12 University Of British Columbia Liposomal formulations of mitoxantrone
ATE252372T1 (de) * 1996-08-23 2003-11-15 Sequus Pharm Inc Liposome enthaltend cisplatin
FR2759293B1 (fr) * 1997-02-11 1999-04-30 Ethypharm Lab Prod Ethiques Microgranules contenant du cisplatine, procede de fabrication, preparation pharmaceutique et utilisation en polychimiotherapie ou en association avec une radiotherapie
CA2399821A1 (en) 2000-02-10 2001-08-16 Liplasome Pharma A/S Lipid-based drug delivery systems containing phospholipase a2 degradable lipid derivatives and the therapeutic uses thereof
WO2001076555A2 (en) 2000-04-12 2001-10-18 Liplasome Pharma A/S Lipid-based drug delivery systems for topical application
US20030026831A1 (en) 2001-04-20 2003-02-06 Aparna Lakkaraju Anionic liposomes for delivery of bioactive agents
CA2383259A1 (en) 2002-04-23 2003-10-23 Celator Technologies Inc. Synergistic compositions
PT1443900E (pt) 2001-11-13 2012-08-01 Celator Pharmaceuticals Inc Composições de veículo lipídico com estabilidade melhorada no sangue
US20040022842A1 (en) 2002-06-03 2004-02-05 Mebiopharm Co., Ltd. Liposome preparations containing oxaliplatin
US20060165744A1 (en) 2003-05-22 2006-07-27 Neopharm, Inc Combination liposomal formulations
GB0312309D0 (en) * 2003-05-29 2003-07-02 Gaslini Children S Hospital G Targeted liposome
JPWO2006025411A1 (ja) 2004-08-31 2008-05-08 アステラス製薬株式会社 細胞内薬物送達改善リポソーム
EP1838283B1 (en) 2004-11-03 2008-12-31 Liplasome Pharma A/S Lipid-based drug delivery systems containing unnatural phospholipase a2 degradable lipid derivatives and the therapeutic uses thereof
WO2007005754A2 (en) * 2005-07-01 2007-01-11 Alza Corporation Liposomal delivery vehicle for hydrophobic drugs
CN101040853B (zh) * 2006-03-22 2010-05-12 上海医药工业研究院 一种草乌甲素多泡脂质体及其制备方法
AU2007229160A1 (en) 2006-03-23 2007-09-27 Liplasome Pharma A/S Lipid based drug delivery systems comprising phospholipase A2 degradable lipids that perform an intramolecular cyclization reaction upon hydrolysis
WO2008006658A1 (en) 2006-07-14 2008-01-17 Fmc Biopolymer As Hydrogels containing low molecular weight alginates and biostructures made therefrom
CN100563646C (zh) 2007-07-13 2009-12-02 陈祥峰 一种奥沙利铂脂质体葡萄糖制剂的制备方法
EP2123258A1 (en) * 2008-05-23 2009-11-25 Liplasome Pharma A/S Liposomes for drug delivery

Also Published As

Publication number Publication date
HRP20140413T1 (hr) 2014-07-04
US9820941B2 (en) 2017-11-21
WO2011047689A3 (en) 2011-11-17
AU2010310240A1 (en) 2012-03-22
JP5778160B2 (ja) 2015-09-16
PT2490671E (pt) 2014-05-30
CA2772973A1 (en) 2011-04-28
AU2010310240B2 (en) 2015-11-26
DK177529B1 (en) 2013-09-08
CN102639114B (zh) 2015-04-01
JP2013508315A (ja) 2013-03-07
RS53321B (sr) 2014-10-31
ES2465565T3 (es) 2014-06-06
EP2490671A2 (en) 2012-08-29
CN102639114A (zh) 2012-08-15
DK200901150A (en) 2011-04-24
SMT201400065B (it) 2014-07-07
DK2490671T3 (da) 2014-06-16
WO2011047689A2 (en) 2011-04-28
EP2490671B1 (en) 2014-03-05
CY1115139T1 (el) 2016-12-14
US20120219618A1 (en) 2012-08-30
CA2772973C (en) 2017-08-15
PL2490671T3 (pl) 2014-08-29

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