SK50932007A3 - Spôsob prípravy vysokočistého meloxikamu a draselnej soli meloxikamu - Google Patents

Spôsob prípravy vysokočistého meloxikamu a draselnej soli meloxikamu Download PDF

Info

Publication number
SK50932007A3
SK50932007A3 SK5093-2007A SK50932007A SK50932007A3 SK 50932007 A3 SK50932007 A3 SK 50932007A3 SK 50932007 A SK50932007 A SK 50932007A SK 50932007 A3 SK50932007 A3 SK 50932007A3
Authority
SK
Slovakia
Prior art keywords
meloxicam
formula
methyl
potassium salt
water
Prior art date
Application number
SK5093-2007A
Other languages
English (en)
Slovak (sk)
Inventor
Tibor Mezei
Gyula Simig
Enik MOLNR
Gyula LUKCS
Marta Porcs-Makkay
Bal�Zs Volk
Fekete Val�Ria Hofmann�
Klmn Nagy
Norbert Mesterh�Zy
Gyrgy KRASZNAI
Don�Th Gy�Rgy Vereczkeyn�
Gyul�N� K�Rtv�Lyessy
�Va P�Csi
Original Assignee
Egis Gy�Gyszergy�R, Nyilv�Nosan M�K�D� R�Szv�Nyt�Rsas�G
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egis Gy�Gyszergy�R, Nyilv�Nosan M�K�D� R�Szv�Nyt�Rsas�G filed Critical Egis Gy�Gyszergy�R, Nyilv�Nosan M�K�D� R�Szv�Nyt�Rsas�G
Publication of SK50932007A3 publication Critical patent/SK50932007A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
SK5093-2007A 2004-12-18 2005-12-16 Spôsob prípravy vysokočistého meloxikamu a draselnej soli meloxikamu SK50932007A3 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU0402634A HU227359B1 (en) 2004-12-18 2004-12-18 Process for producing meloxicam and meloxicam potassium salt of high purity
PCT/HU2005/000136 WO2006064298A1 (en) 2004-12-18 2005-12-16 Process for preparation of high-purity meloxicam and meloxicam potassium salt

Publications (1)

Publication Number Publication Date
SK50932007A3 true SK50932007A3 (sk) 2008-03-05

Family

ID=89985699

Family Applications (1)

Application Number Title Priority Date Filing Date
SK5093-2007A SK50932007A3 (sk) 2004-12-18 2005-12-16 Spôsob prípravy vysokočistého meloxikamu a draselnej soli meloxikamu

Country Status (22)

Country Link
US (2) US8097616B2 (enExample)
EP (1) EP1828178B1 (enExample)
JP (1) JP5329812B2 (enExample)
CN (1) CN101090900B (enExample)
AT (1) ATE486867T1 (enExample)
BG (1) BG66118B1 (enExample)
CY (1) CY1112714T1 (enExample)
CZ (1) CZ2007465A3 (enExample)
DE (1) DE602005024612D1 (enExample)
DK (1) DK1828178T3 (enExample)
EA (1) EA013791B1 (enExample)
ES (1) ES2356840T3 (enExample)
HU (1) HU227359B1 (enExample)
IL (1) IL183739A (enExample)
NO (1) NO20073602L (enExample)
PL (2) PL1828178T3 (enExample)
PT (1) PT1828178E (enExample)
RU (1) RU2394032C2 (enExample)
SI (1) SI1828178T1 (enExample)
SK (1) SK50932007A3 (enExample)
UA (1) UA89657C2 (enExample)
WO (1) WO2006064298A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2443891B (en) * 2006-11-20 2009-04-08 Norbrook Lab Ltd Process for the purification of meloxicam
AU2010286681A1 (en) * 2009-08-27 2012-02-09 Merck Sharp & Dohme Corp. Processes for preparing protease inhibitors of hepatitis C virus
RU2465892C1 (ru) * 2011-09-21 2012-11-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Новосибирский национальный исследовательский государственный университет (НГУ)" Способ получения высокодисперсного мелоксикама
CN103772378B (zh) * 2014-01-26 2016-02-24 悦康药业集团有限公司 一种美洛昔康化合物及其片剂
CN106896162B (zh) * 2015-12-17 2019-10-18 瑞普（天津）生物药业有限公司 一种检测美洛昔康片中杂质的hplc方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2756113A1 (de) * 1977-12-16 1979-06-21 Thomae Gmbh Dr K Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
EP0945134A1 (de) * 1998-03-27 1999-09-29 Boehringer Ingelheim Pharma KG Neue galenische Zubereitungsformen von Meloxicam zur oralen Applikation
ES2223209B1 (es) * 2001-12-11 2005-10-01 Esteve Quimica, S.A. Nuevas formas cristalinas del meloxicam y procedimientos para su preparacion e interconversion.
US8992980B2 (en) * 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
ITMI20041918A1 (it) * 2004-10-11 2005-01-11 A M S A Anonima Materie Sintetiche Affini Spa Processo di purificazione di meloxicam

Also Published As

Publication number Publication date
EP1828178A1 (en) 2007-09-05
EA013791B1 (ru) 2010-06-30
WO2006064298A1 (en) 2006-06-22
HUP0402634A3 (en) 2008-10-28
RU2394032C2 (ru) 2010-07-10
CY1112714T1 (el) 2016-02-10
HUP0402634A2 (en) 2006-11-28
CN101090900B (zh) 2013-11-20
DE602005024612D1 (de) 2010-12-16
PL1828178T3 (pl) 2011-07-29
US8097616B2 (en) 2012-01-17
RU2007126723A (ru) 2009-01-27
JP2008524197A (ja) 2008-07-10
IL183739A0 (en) 2007-09-20
CN101090900A (zh) 2007-12-19
PT1828178E (pt) 2011-02-07
PL382907A1 (pl) 2008-02-04
BG66118B1 (bg) 2011-05-31
US20090215757A1 (en) 2009-08-27
ATE486867T1 (de) 2010-11-15
IL183739A (en) 2011-12-29
US20120035162A1 (en) 2012-02-09
NO20073602L (no) 2007-09-14
HK1114848A1 (en) 2008-11-14
EP1828178B1 (en) 2010-11-03
DK1828178T3 (da) 2011-02-14
HU227359B1 (en) 2011-04-28
JP5329812B2 (ja) 2013-10-30
HU0402634D0 (en) 2005-02-28
UA89657C2 (ru) 2010-02-25
ES2356840T3 (es) 2011-04-13
SI1828178T1 (sl) 2011-03-31
BG109916A (bg) 2008-02-29
CZ2007465A3 (cs) 2007-12-05
EA200701256A1 (ru) 2007-12-28

Similar Documents

Publication Publication Date Title
US7329747B2 (en) Synthesis of olanzapine and intermediates thereof
EP2168969A2 (en) Racemization and Enantiomer Separation of Clopidogrel
US20120035162A1 (en) Process for preparation of high-purity meloxicam and meloxicam potassium salt
FR2468370A1 (fr) Nouvelles pyridothienotriazines et leur procede de preparation
US8143409B2 (en) Crystalline form of rabeprazole sodium
US20080161557A1 (en) Synthesis of 2-Methyl-4-(4-Methyl-1-Piperazinly)-10H-Thieno(2,3-B) (1,5) Benzodiazepine and Salts Thereof
AU2013349260B2 (en) Pyridone derivatives as acid secretion inhibitors and process for preparation thereof
CA2530964A1 (en) Crystalline form of rabeprazole sodium
WO2004072061A1 (en) Method of stabilizing lansoprazole
JP2008524197A5 (enExample)
HK1114848B (en) Process for preparation of high-purity meloxicam and meloxicam potassium salt
EP1711503A1 (en) Synthesis of olanzapine and intermediates thereof
KR100241089B1 (ko) 2-메르캅토-4-메틸-1,3-티아졸-5-아세트산의 신규한제조방법
EP2765131B1 (en) Process for the production of Moxonidine
CA2670464C (en) Process for the purification of meloxicam
WO2007131759A1 (en) A process for the preparation of amlodipine benzenesulfonate
SI21746A (sl) Kristalne oblike olanzapina in postopki za njihovo pripravo

Legal Events

Date Code Title Description
FC9A Refused patent application