NO20073602L - Fremgangsmate for fremstilling av hoyrent meloksikam og meloksikamkaliumsalt - Google Patents
Fremgangsmate for fremstilling av hoyrent meloksikam og meloksikamkaliumsaltInfo
- Publication number
- NO20073602L NO20073602L NO20073602A NO20073602A NO20073602L NO 20073602 L NO20073602 L NO 20073602L NO 20073602 A NO20073602 A NO 20073602A NO 20073602 A NO20073602 A NO 20073602A NO 20073602 L NO20073602 L NO 20073602L
- Authority
- NO
- Norway
- Prior art keywords
- meloxicam
- preparation
- potassium salt
- high pure
- high purity
- Prior art date
Links
- ZRVUJXDFFKFLMG-UHFFFAOYSA-N Meloxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=NC=C(C)S1 ZRVUJXDFFKFLMG-UHFFFAOYSA-N 0.000 title abstract 6
- 229960001929 meloxicam Drugs 0.000 title abstract 6
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 title 1
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 3
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Substances [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000012043 crude product Substances 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 229910000027 potassium carbonate Inorganic materials 0.000 abstract 1
- LTUDISCZKZHRMJ-UHFFFAOYSA-N potassium;hydrate Chemical compound O.[K] LTUDISCZKZHRMJ-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cosmetics (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Oppfinnelsen tilveiebringer en fremgangsmåte for fremstilling av høyrent meloksikam med formel (II). Meloksikam råproduktet reageres med løsningen av kaliumhydroksid eller kaliumkarbonat, hvorved høyrent meloksikam kaliumsaltmonohydrat fremstilles. Det nevnte saltet behandles deretter med mineralsyre eller organisk syre for å gi høyrent meloksikam.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0402634A HU227359B1 (en) | 2004-12-18 | 2004-12-18 | Process for producing meloxicam and meloxicam potassium salt of high purity |
PCT/HU2005/000136 WO2006064298A1 (en) | 2004-12-18 | 2005-12-16 | Process for preparation of high-purity meloxicam and meloxicam potassium salt |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20073602L true NO20073602L (no) | 2007-09-14 |
Family
ID=89985699
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20073602A NO20073602L (no) | 2004-12-18 | 2007-07-12 | Fremgangsmate for fremstilling av hoyrent meloksikam og meloksikamkaliumsalt |
Country Status (23)
Country | Link |
---|---|
US (2) | US8097616B2 (no) |
EP (1) | EP1828178B1 (no) |
JP (1) | JP5329812B2 (no) |
CN (1) | CN101090900B (no) |
AT (1) | ATE486867T1 (no) |
BG (1) | BG66118B1 (no) |
CY (1) | CY1112714T1 (no) |
CZ (1) | CZ2007465A3 (no) |
DE (1) | DE602005024612D1 (no) |
DK (1) | DK1828178T3 (no) |
EA (1) | EA013791B1 (no) |
ES (1) | ES2356840T3 (no) |
HK (1) | HK1114848A1 (no) |
HU (1) | HU227359B1 (no) |
IL (1) | IL183739A (no) |
NO (1) | NO20073602L (no) |
PL (2) | PL382907A1 (no) |
PT (1) | PT1828178E (no) |
RU (1) | RU2394032C2 (no) |
SI (1) | SI1828178T1 (no) |
SK (1) | SK50932007A3 (no) |
UA (1) | UA89657C2 (no) |
WO (1) | WO2006064298A1 (no) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2443891B (en) * | 2006-11-20 | 2009-04-08 | Norbrook Lab Ltd | Process for the purification of meloxicam |
CA2770338A1 (en) * | 2009-08-27 | 2011-03-03 | Merck Sharp & Dohme Corp. | Processes for preparing protease inhibitors of hepatitis c virus |
RU2465892C1 (ru) * | 2011-09-21 | 2012-11-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Новосибирский национальный исследовательский государственный университет (НГУ)" | Способ получения высокодисперсного мелоксикама |
CN103772378B (zh) * | 2014-01-26 | 2016-02-24 | 悦康药业集团有限公司 | 一种美洛昔康化合物及其片剂 |
CN106896162B (zh) * | 2015-12-17 | 2019-10-18 | 瑞普(天津)生物药业有限公司 | 一种检测美洛昔康片中杂质的hplc方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2756113A1 (de) * | 1977-12-16 | 1979-06-21 | Thomae Gmbh Dr K | Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
EP0945134A1 (de) * | 1998-03-27 | 1999-09-29 | Boehringer Ingelheim Pharma KG | Neue galenische Zubereitungsformen von Meloxicam zur oralen Applikation |
ES2223209B1 (es) * | 2001-12-11 | 2005-10-01 | Esteve Quimica, S.A. | Nuevas formas cristalinas del meloxicam y procedimientos para su preparacion e interconversion. |
US8992980B2 (en) * | 2002-10-25 | 2015-03-31 | Boehringer Ingelheim Vetmedica Gmbh | Water-soluble meloxicam granules |
ITMI20041918A1 (it) * | 2004-10-11 | 2005-01-11 | A M S A Anonima Materie Sintetiche Affini Spa | Processo di purificazione di meloxicam |
-
2004
- 2004-12-18 HU HU0402634A patent/HU227359B1/hu not_active IP Right Cessation
-
2005
- 2005-12-16 EP EP05823064A patent/EP1828178B1/en active Active
- 2005-12-16 PT PT05823064T patent/PT1828178E/pt unknown
- 2005-12-16 DK DK05823064.0T patent/DK1828178T3/da active
- 2005-12-16 CN CN2005800434052A patent/CN101090900B/zh not_active Expired - Fee Related
- 2005-12-16 DE DE602005024612T patent/DE602005024612D1/de active Active
- 2005-12-16 ES ES05823064T patent/ES2356840T3/es active Active
- 2005-12-16 PL PL382907A patent/PL382907A1/pl not_active Application Discontinuation
- 2005-12-16 US US11/793,548 patent/US8097616B2/en not_active Expired - Fee Related
- 2005-12-16 EA EA200701256A patent/EA013791B1/ru not_active IP Right Cessation
- 2005-12-16 WO PCT/HU2005/000136 patent/WO2006064298A1/en active Application Filing
- 2005-12-16 RU RU2007126723/04A patent/RU2394032C2/ru not_active IP Right Cessation
- 2005-12-16 SK SK5093-2007A patent/SK50932007A3/sk not_active Application Discontinuation
- 2005-12-16 SI SI200531217T patent/SI1828178T1/sl unknown
- 2005-12-16 CZ CZ20070465A patent/CZ2007465A3/cs unknown
- 2005-12-16 PL PL05823064T patent/PL1828178T3/pl unknown
- 2005-12-16 AT AT05823064T patent/ATE486867T1/de active
- 2005-12-16 JP JP2007546204A patent/JP5329812B2/ja not_active Expired - Fee Related
- 2005-12-16 UA UAA200708233A patent/UA89657C2/ru unknown
-
2007
- 2007-06-07 IL IL183739A patent/IL183739A/en not_active IP Right Cessation
- 2007-07-12 NO NO20073602A patent/NO20073602L/no unknown
- 2007-07-18 BG BG109916A patent/BG66118B1/bg unknown
-
2008
- 2008-05-02 HK HK08104873.6A patent/HK1114848A1/xx not_active IP Right Cessation
-
2011
- 2011-01-28 CY CY20111100084T patent/CY1112714T1/el unknown
- 2011-10-12 US US13/271,445 patent/US20120035162A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2006027705A3 (en) | Synthesis of triethylenetetramines | |
SI1751093T1 (sl) | Substituirani derivati cikloheksilocetne kisline | |
NO20073602L (no) | Fremgangsmate for fremstilling av hoyrent meloksikam og meloksikamkaliumsalt | |
AR078916A1 (es) | Procedimiento para la purificacion de paliperidona | |
TNSN07465A1 (en) | Organic compounds | |
SI1902036T1 (sl) | Postopek za pripravo rosuvastatina in intermediatov | |
DE502005010080D1 (de) | Ingem chlorid-gehalt | |
HK1114101A1 (no) | ||
WO2009072501A1 (ja) | カーボネート化合物の製造方法 | |
WO2007003200A3 (en) | High yield synthesis methods for producing organic salts of strontium | |
NO20082005L (no) | Syntese av renininhibitorer omfattende en cyklotilfoyelsesreaksjon | |
IL200323A0 (en) | Synthesis of glyt-1 inhibitors | |
IL198965A0 (en) | Process for preparation of abacavir | |
MXPA05008088A (es) | Proceso mejorado para preparar benzhidril tioacetamida. | |
WO2009006066A3 (en) | Process for the preparation of benzimidazol thienylamine compounds and intermediates thereof | |
BR112013006471A2 (pt) | produção de isopreno a partir de isobutanol | |
AU2016102231A4 (en) | Carbenicillin drug intermediates phenyl malonic acid benzyl ester synthesis method | |
WO2010004580A3 (en) | Process for preparing indole derivatives | |
ATE487712T1 (de) | Verwendung der monoxidinssalze zur reinigung von monoxidin | |
CN104119296A (zh) | 一种2-三氟甲基-5-哌嗪基-噻二唑的合成方法 | |
TH73543B (th) | กรรมวิธีการผลิตกรดซัคซินิกและสารละลายแอมโมเนียมซัคซิเนต | |
BR0303440A (pt) | Processo para a produção de um carboxilato de cálcio |