SK386392A3 - Interferon alpha - Google Patents
Interferon alpha Download PDFInfo
- Publication number
- SK386392A3 SK386392A3 SK3863-92A SK386392A SK386392A3 SK 386392 A3 SK386392 A3 SK 386392A3 SK 386392 A SK386392 A SK 386392A SK 386392 A3 SK386392 A3 SK 386392A3
- Authority
- SK
- Slovakia
- Prior art keywords
- ifn
- plasmid
- alpha2
- alpha2c
- peak
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Plant Pathology (AREA)
- Communicable Diseases (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19904021917 DE4021917A1 (de) | 1990-07-10 | 1990-07-10 | Glykosyliertes ifnalpha |
DE19904035877 DE4035877A1 (de) | 1990-11-12 | 1990-11-12 | O-glycosyliertes ifn-alfa2 |
PCT/EP1991/001266 WO1992001055A1 (de) | 1990-07-10 | 1991-07-06 | O-glycosyliertes ifn-alpha |
Publications (1)
Publication Number | Publication Date |
---|---|
SK386392A3 true SK386392A3 (en) | 1994-08-10 |
Family
ID=25894855
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK3863-92A SK386392A3 (en) | 1990-07-10 | 1991-07-06 | Interferon alpha |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0538300B1 (da) |
JP (1) | JPH06502987A (da) |
KR (1) | KR930701601A (da) |
AT (1) | ATE104348T1 (da) |
AU (1) | AU650893B2 (da) |
CA (1) | CA2084514A1 (da) |
CZ (1) | CZ386392A3 (da) |
DE (1) | DE59101397D1 (da) |
DK (1) | DK0538300T3 (da) |
ES (1) | ES2063515T3 (da) |
FI (1) | FI930058A0 (da) |
HU (1) | HUT65846A (da) |
NO (1) | NO930059D0 (da) |
PL (1) | PL297610A1 (da) |
SK (1) | SK386392A3 (da) |
WO (1) | WO1992001055A1 (da) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ245771A (en) * | 1992-02-07 | 1994-08-26 | New England Medical Center Inc | Mammalian gastrin/cholecystokinin b (cck-b) receptor and antagonists |
US5541071A (en) * | 1992-02-07 | 1996-07-30 | New England Medical Center Hospitals, Inc. | Assay for identifying antagonists of gastrin and CCK-B receptors |
EP0626448A3 (de) * | 1993-05-26 | 1998-01-14 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Verfahren zur Herstellung und Reinigung von alpha-Interferon |
EP0788556A1 (en) * | 1994-10-28 | 1997-08-13 | Innogenetics N.V. | New polynucleic acid sequences for use in the detection and differentiation of prokaryotic organisms |
EP0920522B1 (en) * | 1996-08-14 | 2003-10-29 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | A vector for polynucleotide vaccines |
GB9904695D0 (en) * | 1999-03-01 | 1999-04-21 | Imp Cancer Res Tech | Peptide |
JP2003531590A (ja) | 2000-04-12 | 2003-10-28 | ヒューマン ゲノム サイエンシズ インコーポレイテッド | アルブミン融合タンパク質 |
DK2279753T3 (da) * | 2001-10-10 | 2015-11-23 | Novo Nordisk As | Omdannelse og glycokonjugering af peptider |
US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
US7214660B2 (en) | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
EP1997829A1 (en) | 2001-12-21 | 2008-12-03 | Human Genome Sciences, Inc. | Albumin fusion proteins |
MXPA05009726A (es) | 2003-03-14 | 2005-11-04 | Neose Technologies Inc | Polimeros ramificados, solubles en agua y sus conjugados. |
CA2522345A1 (en) | 2003-04-09 | 2004-11-18 | Neose Technologies, Inc. | Glycopegylation methods and proteins/peptides produced by the methods |
US8791070B2 (en) | 2003-04-09 | 2014-07-29 | Novo Nordisk A/S | Glycopegylated factor IX |
WO2005012484A2 (en) | 2003-07-25 | 2005-02-10 | Neose Technologies, Inc. | Antibody-toxin conjugates |
US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
US8633157B2 (en) | 2003-11-24 | 2014-01-21 | Novo Nordisk A/S | Glycopegylated erythropoietin |
US20060040856A1 (en) | 2003-12-03 | 2006-02-23 | Neose Technologies, Inc. | Glycopegylated factor IX |
US8361961B2 (en) | 2004-01-08 | 2013-01-29 | Biogenerix Ag | O-linked glycosylation of peptides |
WO2006010143A2 (en) | 2004-07-13 | 2006-01-26 | Neose Technologies, Inc. | Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1] |
EP1799249A2 (en) | 2004-09-10 | 2007-06-27 | Neose Technologies, Inc. | Glycopegylated interferon alpha |
EP3061461A1 (en) | 2004-10-29 | 2016-08-31 | ratiopharm GmbH | Remodeling and glycopegylation of fibroblast growth factor (fgf) |
NZ556436A (en) | 2005-01-10 | 2010-11-26 | Biogenerix Ag | Glycopegylated granulocyte colony stimulating factor |
EP2386571B1 (en) | 2005-04-08 | 2016-06-01 | ratiopharm GmbH | Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants |
JP5216580B2 (ja) | 2005-05-25 | 2013-06-19 | ノヴォ ノルディスク アー/エス | グリコペグ化第ix因子 |
US20070105755A1 (en) | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
US20090048440A1 (en) | 2005-11-03 | 2009-02-19 | Neose Technologies, Inc. | Nucleotide Sugar Purification Using Membranes |
AR078117A1 (es) | 2006-06-20 | 2011-10-19 | Protech Pharma S A | Una muteina recombinante del interferon alfa humano glicosilado, un gen que codifica para dicha muteina, un metodo de produccion de dicho gen, un metodo para obtener una celula eucariota productora de dicha muteina, un metodo para producir dicha muteina, un procedimiento para purificar dicha muteina |
US20080248959A1 (en) | 2006-07-21 | 2008-10-09 | Neose Technologies, Inc. | Glycosylation of peptides via o-linked glycosylation sequences |
JP2010505874A (ja) | 2006-10-03 | 2010-02-25 | ノヴォ ノルディスク アー/エス | ポリペプチドコンジュゲートの精製方法 |
NZ580030A (en) | 2007-04-03 | 2012-06-29 | Biogenerix Ag | Methods of treatment using glycopegylated g-csf |
EP2170919B8 (en) | 2007-06-12 | 2016-01-20 | ratiopharm GmbH | Improved process for the production of nucleotide sugars |
US8207112B2 (en) | 2007-08-29 | 2012-06-26 | Biogenerix Ag | Liquid formulation of G-CSF conjugate |
CA2715465C (en) | 2008-02-27 | 2017-03-21 | Novo Nordisk A/S | Conjugated factor viii molecules |
WO2014102103A2 (en) | 2012-12-31 | 2014-07-03 | Boehringer Ingelheim International Gmbh | Heterologous intron within a signal peptide |
WO2014102101A1 (en) | 2012-12-31 | 2014-07-03 | Boehringer Ingelheim International Gmbh | Novel intron sequences |
RU2610173C1 (ru) * | 2016-03-30 | 2017-02-08 | Илья Александрович Марков | Рекомбинантная плазмида pFM-IFN-17, обеспечивающая экспрессию интерферона альфа-2b человека, рекомбинантная плазмида pFM-АР, обеспечивающая экспрессию фермента метионинаминопептидазы E. coli, биплазмидный штамм Escherichia coli FM-IFN-АР (pFM-IFN-17, pFM-АР) - продуцент (Met-) рекомбинантного интерферона альфа-2b человека |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN150740B (da) * | 1978-11-24 | 1982-12-04 | Hoffmann La Roche | |
JPS58501543A (ja) * | 1981-08-14 | 1983-09-16 | エイ/エス アルフレツド ベンツオン | ヒトインタ−フエロン蛋白とヒトインタ−フエロン蛋白に対する抗体に関する改良 |
DE3306060A1 (de) * | 1983-02-22 | 1984-08-23 | Boehringer Ingelheim International GmbH, 6507 Ingelheim | Neue immunglobulin-produzierende hybridzellinien, deren verwendung und verfahren zu deren herstellung |
FR2560212B1 (fr) * | 1984-02-24 | 1989-12-29 | Unicet | Anticorps monoclonaux contre l'interferon a2 et hybridomes produisant de tels anticorps |
-
1991
- 1991-07-06 WO PCT/EP1991/001266 patent/WO1992001055A1/de not_active Application Discontinuation
- 1991-07-06 AU AU82082/91A patent/AU650893B2/en not_active Ceased
- 1991-07-06 DK DK91912306.7T patent/DK0538300T3/da active
- 1991-07-06 CA CA002084514A patent/CA2084514A1/en not_active Abandoned
- 1991-07-06 PL PL29761091A patent/PL297610A1/xx unknown
- 1991-07-06 SK SK3863-92A patent/SK386392A3/sk unknown
- 1991-07-06 ES ES91912306T patent/ES2063515T3/es not_active Expired - Lifetime
- 1991-07-06 JP JP3511638A patent/JPH06502987A/ja active Pending
- 1991-07-06 HU HU9300036A patent/HUT65846A/hu unknown
- 1991-07-06 AT AT91912306T patent/ATE104348T1/de not_active IP Right Cessation
- 1991-07-06 DE DE59101397T patent/DE59101397D1/de not_active Expired - Fee Related
- 1991-07-06 EP EP91912306A patent/EP0538300B1/de not_active Expired - Lifetime
- 1991-07-06 KR KR1019930700049A patent/KR930701601A/ko not_active Application Discontinuation
-
1992
- 1992-12-23 CZ CS923863A patent/CZ386392A3/cs unknown
-
1993
- 1993-01-08 FI FI930058A patent/FI930058A0/fi not_active Application Discontinuation
- 1993-01-08 NO NO930059A patent/NO930059D0/no unknown
Also Published As
Publication number | Publication date |
---|---|
AU650893B2 (en) | 1994-07-07 |
WO1992001055A1 (de) | 1992-01-23 |
ES2063515T3 (es) | 1995-01-01 |
KR930701601A (ko) | 1993-06-12 |
NO930059L (no) | 1993-01-08 |
CZ386392A3 (en) | 1993-08-11 |
PL297610A1 (da) | 1992-07-13 |
HU9300036D0 (en) | 1993-04-28 |
CA2084514A1 (en) | 1992-01-11 |
ATE104348T1 (de) | 1994-04-15 |
JPH06502987A (ja) | 1994-04-07 |
NO930059D0 (no) | 1993-01-08 |
EP0538300A1 (de) | 1993-04-28 |
FI930058A (fi) | 1993-01-08 |
EP0538300B1 (de) | 1994-04-13 |
AU8208291A (en) | 1992-02-04 |
HUT65846A (en) | 1994-07-28 |
DE59101397D1 (de) | 1994-05-19 |
FI930058A0 (fi) | 1993-01-08 |
DK0538300T3 (da) | 1994-10-10 |
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