SK332387A3 - Tripeptide derivative, method of its prepartion and pharmaceutical agent containing this derivative - Google Patents

Tripeptide derivative, method of its prepartion and pharmaceutical agent containing this derivative Download PDF

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Publication number
SK332387A3
SK332387A3 SK3323-87A SK332387A SK332387A3 SK 332387 A3 SK332387 A3 SK 332387A3 SK 332387 A SK332387 A SK 332387A SK 332387 A3 SK332387 A3 SK 332387A3
Authority
SK
Slovakia
Prior art keywords
group
alkyl
formula
hydroxy
gamma
Prior art date
Application number
SK3323-87A
Other languages
English (en)
Slovak (sk)
Other versions
SK278137B6 (en
Inventor
Tadahiro Sawayama
Masatoshi Tsukamoto
Takashi Sasagawa
Kazuya Nishimura
Kanoo Hosoki
Kunihiko Takeyama
Original Assignee
Lt Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lt Dainippon Pharmaceutical Co filed Critical Lt Dainippon Pharmaceutical Co
Publication of SK332387A3 publication Critical patent/SK332387A3/sk
Publication of SK278137B6 publication Critical patent/SK278137B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
SK3323-87A 1986-05-09 1987-05-08 Tripeptide derivative, method of its preparation and pharmaceutical agent containing this derivative SK278137B6 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP10739486 1986-05-09
JP15669386 1986-07-03
JP1636187 1987-01-26

Publications (2)

Publication Number Publication Date
SK332387A3 true SK332387A3 (en) 1996-02-07
SK278137B6 SK278137B6 (en) 1996-02-07

Family

ID=27281373

Family Applications (1)

Application Number Title Priority Date Filing Date
SK3323-87A SK278137B6 (en) 1986-05-09 1987-05-08 Tripeptide derivative, method of its preparation and pharmaceutical agent containing this derivative

Country Status (16)

Country Link
US (1) US4826814A (da)
EP (1) EP0244836B1 (da)
JP (1) JPS63295597A (da)
KR (1) KR870011152A (da)
AU (1) AU595309B2 (da)
CA (1) CA1318461C (da)
CZ (1) CZ280776B6 (da)
DE (1) DE3787042T2 (da)
DK (1) DK171402B1 (da)
ES (1) ES2058074T3 (da)
FI (1) FI87794C (da)
HU (1) HU202884B (da)
MX (1) MX174530B (da)
NZ (1) NZ220173A (da)
SK (1) SK278137B6 (da)
SU (1) SU1743356A3 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0394311A1 (en) * 1987-11-16 1990-10-31 The Upjohn Company Renin inhibiting peptides that contain amino and hydroxy dicarboxylic acids
FR2649110B1 (fr) * 1989-06-29 1994-10-21 Adir Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US5391705A (en) * 1991-03-15 1995-02-21 Merrell Dow Pharmaceuticals Inc. Polyfluorinated tripeptide thrombin inhibitors
US6764693B1 (en) 1992-12-11 2004-07-20 Amaox, Ltd. Free radical quenching composition and a method to increase intracellular and/or extracellular antioxidants
EP0684148B1 (en) * 1994-05-27 2003-03-12 Cubic Co., Ltd. Decorated shaped product
WO1996034011A1 (fr) * 1995-04-27 1996-10-31 Dainippon Pharmaceutical Co., Ltd. Procedes de purification
US6069232A (en) * 1995-10-02 2000-05-30 Hoechst Marion Roussel, Inc. Polyfluoroalkyl tryptophan tripeptide thrombin inhibitors
US5739354A (en) * 1996-03-26 1998-04-14 Hoechst Marion Roussel, Inc. Process for the preparation of N-methyl-D-phenylalanyl-N- 1- 3- (aminoiminomethyl)amino!propyl!-3,3-difluoro-2-oxohexyl!-L-prolinamide
MXPA04005557A (es) * 2002-03-01 2005-05-17 Warner Lambert Co Metodo para tratar la osteoartritis.
CN114920676B (zh) * 2022-06-07 2024-04-05 四川国康药业有限公司 一种治疗呼吸系统疾病的化合物及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215110A (en) * 1978-09-22 1980-07-29 Merck & Co., Inc. Method of treating hypertension
DE3381378D1 (de) * 1982-01-23 1990-05-03 Ajinomoto Kk Derivate von aminosaeuren und antihypertensive arzneimittel diese enthaltend.
JPS59227851A (ja) * 1983-06-09 1984-12-21 Sankyo Co Ltd レニン阻害作用を有するペプチド類
US4678800A (en) * 1984-06-15 1987-07-07 Ciba-Geigy Corporation Gamma-r-glutamoyl derivatives
US4616002A (en) * 1984-11-09 1986-10-07 Ciba-Geigy Corporation Dihydro pyridine compounds, compositions and use
DE3619633A1 (de) * 1986-06-11 1987-12-17 Hoechst Ag Peptide mit einfluss auf die diurese und natriurese, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
DE3640535A1 (de) * 1986-11-27 1988-06-01 Merck Patent Gmbh Peptide
DK523288A (da) * 1987-10-06 1989-04-07 Hoffmann La Roche Aminosyrederivater

Also Published As

Publication number Publication date
AU7241687A (en) 1987-11-12
EP0244836A3 (en) 1989-11-23
DK235787D0 (da) 1987-05-08
CA1318461C (en) 1993-05-25
DE3787042T2 (de) 1994-01-27
AU595309B2 (en) 1990-03-29
EP0244836B1 (en) 1993-08-18
EP0244836A2 (en) 1987-11-11
FI87794C (fi) 1993-02-25
NZ220173A (en) 1990-01-29
FI872041A0 (fi) 1987-05-08
FI87794B (fi) 1992-11-13
JPS63295597A (ja) 1988-12-01
CZ280776B6 (cs) 1996-04-17
MX174530B (es) 1994-05-24
DK171402B1 (da) 1996-10-14
HUT45268A (en) 1988-06-28
SK278137B6 (en) 1996-02-07
DE3787042D1 (de) 1993-09-23
FI872041A (fi) 1987-11-10
SU1743356A3 (ru) 1992-06-23
CZ332387A3 (en) 1995-11-15
KR870011152A (ko) 1987-12-21
US4826814A (en) 1989-05-02
HU202884B (en) 1991-04-29
MX6424A (es) 1993-09-01
ES2058074T3 (es) 1994-11-01
DK235787A (da) 1987-11-10

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