SK287583B6 - (Pyrido/tieno)-[f]-oxazepin-5-ónové deriváty, farmaceutický prostriedok s ich obsahom a ich použitie - Google Patents

(Pyrido/tieno)-[f]-oxazepin-5-ónové deriváty, farmaceutický prostriedok s ich obsahom a ich použitie Download PDF

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Publication number
SK287583B6
SK287583B6 SK1526-2003A SK15262003A SK287583B6 SK 287583 B6 SK287583 B6 SK 287583B6 SK 15262003 A SK15262003 A SK 15262003A SK 287583 B6 SK287583 B6 SK 287583B6
Authority
SK
Slovakia
Prior art keywords
pyrido
alkyl
oxazepin
thieno
formula
Prior art date
Application number
SK1526-2003A
Other languages
English (en)
Slovak (sk)
Other versions
SK15262003A3 (sk
Inventor
Simon James Anthony Grove
- Worrall Julia Adam
Mingqiang Zhang
Robert Gilfillan
Original Assignee
N.V. Organon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by N.V. Organon filed Critical N.V. Organon
Publication of SK15262003A3 publication Critical patent/SK15262003A3/sk
Publication of SK287583B6 publication Critical patent/SK287583B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SK1526-2003A 2001-06-14 2002-06-10 (Pyrido/tieno)-[f]-oxazepin-5-ónové deriváty, farmaceutický prostriedok s ich obsahom a ich použitie SK287583B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01202284 2001-06-14
PCT/EP2002/006364 WO2002102808A2 (en) 2001-06-14 2002-06-10 (PYRIDO/THIENO)-[f]-OXAZEPIN-5-ONE DERIVATIVES AS POSITIVE MODULATORS OF THE AMPA RECEPTOR

Publications (2)

Publication Number Publication Date
SK15262003A3 SK15262003A3 (sk) 2004-05-04
SK287583B6 true SK287583B6 (sk) 2011-03-04

Family

ID=8180476

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1526-2003A SK287583B6 (sk) 2001-06-14 2002-06-10 (Pyrido/tieno)-[f]-oxazepin-5-ónové deriváty, farmaceutický prostriedok s ich obsahom a ich použitie

Country Status (25)

Country Link
US (3) US7345036B2 (es)
EP (1) EP1446407A2 (es)
JP (1) JP4435562B2 (es)
KR (1) KR100864267B1 (es)
CN (2) CN101029051B (es)
AR (1) AR034482A1 (es)
AU (1) AU2002320841B2 (es)
BR (1) BR0210307A (es)
CA (1) CA2449215C (es)
CO (1) CO5550448A2 (es)
CZ (1) CZ296217B6 (es)
EC (1) ECSP034890A (es)
HR (1) HRP20031013A2 (es)
HU (1) HUP0400196A3 (es)
IL (2) IL158928A0 (es)
IS (1) IS7042A (es)
MX (1) MXPA03011562A (es)
NO (1) NO328710B1 (es)
NZ (1) NZ529671A (es)
PE (1) PE20030271A1 (es)
PL (1) PL367185A1 (es)
RU (1) RU2286347C2 (es)
SK (1) SK287583B6 (es)
WO (1) WO2002102808A2 (es)
ZA (1) ZA200309096B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200817385A (en) * 2006-07-04 2008-04-16 Organon Nv Heterocyclic derivatives
FR2964969B1 (fr) * 2010-09-16 2012-08-24 Servier Lab Nouveaux derives dihydrobenzoxathiazepines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1238719A (es) 1968-11-01 1971-07-07
AU688271B2 (en) 1992-07-24 1998-03-12 Regents Of The University Of California, The Drugs that enhance synaptic responses mediated by ampa receptors
ATE203026T1 (de) * 1995-01-06 2001-07-15 Hoffmann La Roche Hydroxymethyl-imidazodiazepine und deren ester
US5650409A (en) * 1995-06-02 1997-07-22 Cortex Pharmaceuticals, Inc. Benzoyl piperidines/pyrrolidines for enhancing synaptic response
US5736543A (en) * 1996-04-03 1998-04-07 The Regents Of The University Of California Benzoxazines for enhancing synaptic response
ES2245015T3 (es) * 1997-06-09 2005-12-16 Pfizer Products Inc. Quinazolin-4-onas como antagonistas de ampa.
US5985871A (en) 1997-12-24 1999-11-16 Cortex Pharmaceuticals, Inc. Benzoxazine compounds for enhancing synaptic response
TR200002427T2 (tr) * 1998-02-18 2001-01-22 Neurosearch A/S Yeni bileşikler ve bunların pozitif ampa reseptör modülatörleri olarak kullanımı.
US6124278A (en) 1998-04-03 2000-09-26 The Regents Of The University Of California Acylbenzoxazines for enhancing synaptic response
EP1187837B1 (en) 1999-05-12 2007-07-18 THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Thiazepine inhibitors of hiv-1 integrase
TWI232863B (en) 2001-06-11 2005-05-21 Akzo Nobel Nv Benzoxazepine derivatives

Also Published As

Publication number Publication date
IS7042A (is) 2003-11-17
US20040220175A1 (en) 2004-11-04
WO2002102808A2 (en) 2002-12-27
CA2449215C (en) 2011-03-22
EP1446407A2 (en) 2004-08-18
RU2286347C2 (ru) 2006-10-27
SK15262003A3 (sk) 2004-05-04
US7566778B2 (en) 2009-07-28
CN101029051A (zh) 2007-09-05
KR20040007703A (ko) 2004-01-24
WO2002102808A3 (en) 2003-03-20
ECSP034890A (es) 2004-01-28
CZ296217B6 (cs) 2006-02-15
NO328710B1 (no) 2010-05-03
NO20035523D0 (no) 2003-12-11
US20080262221A1 (en) 2008-10-23
MXPA03011562A (es) 2004-03-18
KR100864267B1 (ko) 2008-10-20
HUP0400196A3 (en) 2007-05-02
IL158928A0 (en) 2004-05-12
CA2449215A1 (en) 2002-12-27
US7345036B2 (en) 2008-03-18
CN1255413C (zh) 2006-05-10
RU2004100702A (ru) 2005-06-10
ZA200309096B (en) 2005-02-21
JP2005500301A (ja) 2005-01-06
CN1516701A (zh) 2004-07-28
HRP20031013A2 (hr) 2005-10-31
IL158928A (en) 2008-11-26
CZ20033392A3 (en) 2004-05-12
PE20030271A1 (es) 2003-03-19
HUP0400196A2 (hu) 2004-07-28
US20090163473A1 (en) 2009-06-25
NZ529671A (en) 2005-10-28
PL367185A1 (en) 2005-02-21
CN101029051B (zh) 2010-06-09
BR0210307A (pt) 2004-07-13
JP4435562B2 (ja) 2010-03-17
AR034482A1 (es) 2004-02-25
US8034804B2 (en) 2011-10-11
AU2002320841B2 (en) 2008-02-28
CO5550448A2 (es) 2005-08-31

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SK287583B6 (sk) (Pyrido/tieno)-[f]-oxazepin-5-ónové deriváty, farmaceutický prostriedok s ich obsahom a ich použitie
AU2002314144A1 (en) Benzoxazepine derivatives and their use as AMPA receptor stimulators
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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20120610