SK287192B6 - Mezoprogestíny (modulátory receptora pre progesterón) na liečenie a prevenciu benígnych gynekologických ochorení závislých od hormónov - Google Patents

Mezoprogestíny (modulátory receptora pre progesterón) na liečenie a prevenciu benígnych gynekologických ochorení závislých od hormónov Download PDF

Info

Publication number
SK287192B6
SK287192B6 SK299-2002A SK2992002A SK287192B6 SK 287192 B6 SK287192 B6 SK 287192B6 SK 2992002 A SK2992002 A SK 2992002A SK 287192 B6 SK287192 B6 SK 287192B6
Authority
SK
Slovakia
Prior art keywords
treatment
mesoprogestins
prevention
mesoprogestin
endometriosis
Prior art date
Application number
SK299-2002A
Other languages
English (en)
Slovak (sk)
Other versions
SK2992002A3 (en
Inventor
Kristof Chwalisz
Walter Elger
Gerd Schubert
Original Assignee
Bayer Schering Pharma Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Aktiengesellschaft filed Critical Bayer Schering Pharma Aktiengesellschaft
Publication of SK2992002A3 publication Critical patent/SK2992002A3/sk
Publication of SK287192B6 publication Critical patent/SK287192B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Pyridine Compounds (AREA)
SK299-2002A 1999-08-31 2000-08-31 Mezoprogestíny (modulátory receptora pre progesterón) na liečenie a prevenciu benígnych gynekologických ochorení závislých od hormónov SK287192B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38614199A 1999-08-31 1999-08-31
PCT/US2000/023770 WO2001015679A2 (en) 1999-08-31 2000-08-31 Mesoprogestins for the treatment and prevention of benign hormone dependent gynecological disorders

Publications (2)

Publication Number Publication Date
SK2992002A3 SK2992002A3 (en) 2002-07-02
SK287192B6 true SK287192B6 (sk) 2010-02-08

Family

ID=23524338

Family Applications (1)

Application Number Title Priority Date Filing Date
SK299-2002A SK287192B6 (sk) 1999-08-31 2000-08-31 Mezoprogestíny (modulátory receptora pre progesterón) na liečenie a prevenciu benígnych gynekologických ochorení závislých od hormónov

Country Status (34)

Country Link
EP (1) EP1229906B1 (pl)
JP (1) JP2003535029A (pl)
KR (3) KR100755109B1 (pl)
AR (1) AR025457A1 (pl)
AT (1) ATE375160T1 (pl)
AU (1) AU781840B2 (pl)
BG (1) BG65817B1 (pl)
BR (1) BR0014161A (pl)
CA (1) CA2382580C (pl)
CO (1) CO5200772A1 (pl)
CZ (1) CZ2002704A3 (pl)
DE (1) DE60036723T2 (pl)
DK (1) DK1229906T3 (pl)
EA (1) EA007854B1 (pl)
EE (1) EE05172B1 (pl)
ES (1) ES2295050T3 (pl)
HR (1) HRP20020267A2 (pl)
HU (1) HUP0202429A3 (pl)
IL (1) IL148416A0 (pl)
LT (1) LT5034B (pl)
LV (1) LV12941B (pl)
ME (1) MEP13808A (pl)
MX (1) MXPA02002191A (pl)
NO (1) NO20020999L (pl)
NZ (1) NZ517471A (pl)
PE (1) PE20010578A1 (pl)
PL (1) PL198790B1 (pl)
PT (1) PT1229906E (pl)
RO (1) RO122179B1 (pl)
RS (1) RS50283B (pl)
SI (1) SI20852B (pl)
SK (1) SK287192B6 (pl)
UA (1) UA78184C2 (pl)
WO (1) WO2001015679A2 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004014935A1 (de) * 2002-08-02 2004-02-19 Schering Aktiengesellschaft Progesteronrezeptormodulatoren mit erhöhter antigonadotroper aktivität für die weibliche fertilitätskontrolle und hormonersatztherapie
DE10236405A1 (de) 2002-08-02 2004-02-19 Schering Ag Progesteronrezeptormodulatoren mit erhöhter antigonadotroper Aktivität für die weibliche Fertilitätskontrolle und Hormonersatztherapie
US20040097591A1 (en) * 2002-11-18 2004-05-20 Kristof Chwalisz Use of selective progesterone receptor modulators for the treatment of androgen deficiency
DE102007011105A1 (de) 2007-03-02 2008-09-04 Bayer Schering Pharma Aktiengesellschaft Mineralcorticoid-Rezeptor-Antagonisten zur Behandlung von Endometriose
WO2010147184A1 (ja) * 2009-06-17 2010-12-23 国立大学法人熊本大学 月経困難症の予防及び／又は治療薬
US8399432B2 (en) * 2009-10-27 2013-03-19 Lipogen Ltd. Compositions and methods of treatment for alleviating premenstrual syndrome symptoms
JP2022548314A (ja) * 2019-09-23 2022-11-17 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 妊娠を遷延させるためおよび月経または妊娠の合併症の処置の方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3633244A1 (de) 1986-09-26 1988-03-31 Schering Ag Antigestagene zur hemmung der uterinen prostaglandinsynthese
DE4332284C2 (de) 1993-09-20 1997-05-28 Jenapharm Gmbh 11-Benzaldoxim-17beta-methoxy-17alpha-methoxymethyl-estradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE4332283A1 (de) * 1993-09-20 1995-04-13 Jenapharm Gmbh Neue 11-Benzaldoximestradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US5681817A (en) * 1994-02-04 1997-10-28 The Medical College Of Hampton Roads Treatment of ovarian estrogen dependent conditions
US5576310A (en) * 1994-09-20 1996-11-19 Jenapharm Gmbh 11-benzaldoxime-17β-methoxy-17α-methoxymethyl-estrasdiene derivatives, methods for their production and pharmaceuticals containing such compounds
ATE252560T1 (de) * 1994-12-22 2003-11-15 Ligand Pharm Inc Steroidrezeptor-modulator verbindungen und methoden
US5693647A (en) * 1994-12-22 1997-12-02 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
PT806952E (pt) 1995-02-02 2003-08-29 Schering Ag Antagonistas da progesterona para a preparacao de medicamentos para o tratamento de hemorragias uterinas disfuncionais
DE19604231A1 (de) * 1996-01-29 1997-07-31 Schering Ag Pharmazeutisches Kombinationspräparat und seine Verwendung zur Behandlung von gynäkologischen Störungen
EP0900234B1 (en) * 1996-05-01 2000-07-05 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES 21-substituted progesterone derivatives as new antiprogestational agents
WO1998005679A2 (en) * 1996-08-05 1998-02-12 Duke University Mixed agonists of the progesterone receptor and assays therefor
DE19809845A1 (de) * 1998-03-03 1999-09-09 Jenapharm Gmbh S-substituierte 11beta-Benzaldoxim-estra-4,9-dien-kohlensäurethiolester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
KR20010089831A (ko) * 1999-01-14 2001-10-08 조지 제이. 리코스 프로게스테론 수용체 결합제로 사용되는 치환된2-아릴이미노 헤테로싸이클 및 이를 포함하는 조성물
CA2371273A1 (en) * 1999-05-04 2000-11-09 Andrew Fensome Tetracyclic progesterone receptor modulator compounds and methods

Also Published As

Publication number Publication date
BR0014161A (pt) 2002-05-21
WO2001015679A3 (en) 2001-11-22
LT2002031A (en) 2003-02-25
MXPA02002191A (es) 2002-09-30
DE60036723T2 (de) 2008-07-17
EA007854B1 (ru) 2007-02-27
HUP0202429A3 (en) 2004-04-28
AU6946600A (en) 2001-03-26
ATE375160T1 (de) 2007-10-15
PL198790B1 (pl) 2008-07-31
CA2382580A1 (en) 2001-03-08
PE20010578A1 (es) 2001-06-04
EE05172B1 (et) 2009-06-15
DK1229906T3 (da) 2008-02-11
ES2295050T3 (es) 2008-04-16
KR20020027616A (ko) 2002-04-13
CA2382580C (en) 2009-05-19
RO122179B1 (ro) 2009-02-27
PT1229906E (pt) 2008-01-18
AU781840B2 (en) 2005-06-16
EP1229906B1 (en) 2007-10-10
DE60036723D1 (de) 2007-11-22
LV12941B (en) 2003-06-20
WO2001015679A2 (en) 2001-03-08
AR025457A1 (es) 2002-11-27
CZ2002704A3 (cs) 2003-02-12
MEP13808A (en) 2010-06-10
IL148416A0 (en) 2002-09-12
NO20020999D0 (no) 2002-02-28
UA78184C2 (en) 2007-03-15
HUP0202429A2 (en) 2002-10-28
LT5034B (lt) 2003-07-25
CO5200772A1 (es) 2002-09-27
SI20852B (sl) 2009-06-30
NZ517471A (en) 2004-02-27
EP1229906A2 (en) 2002-08-14
EA200200282A1 (ru) 2002-10-31
KR20070058023A (ko) 2007-06-07
BG65817B1 (bg) 2010-01-29
RS50283B (sr) 2009-09-08
EE200200104A (et) 2003-04-15
PL353930A1 (pl) 2003-12-15
KR20080066095A (ko) 2008-07-15
KR100755109B1 (ko) 2007-09-04
BG106442A (bg) 2002-09-30
SK2992002A3 (en) 2002-07-02
YU14002A (sh) 2006-01-16
NO20020999L (no) 2002-03-14
JP2003535029A (ja) 2003-11-25
KR100864547B1 (ko) 2008-10-20
HRP20020267A2 (en) 2004-04-30
SI20852A (sl) 2002-10-31

Similar Documents

Publication Publication Date Title
SK78997A3 (en) Compounds with progesterone-antagonistic and anti-oestrogen properties intended for combined use in female contraception
CA2382580C (en) Mesoprogestins (progesterone receptor modulators) for the treatment and prevention of benign hormone dependent gynecological disorders
AU781835B2 (en) Mesoprogestins (progesterone receptor modulators) as a component of female contraceptives
US8193252B1 (en) Mesoprogestins (progesterone receptor modulators) for the treatment and prevention of benign hormone dependent gynecological disorders
Ashok et al. The antiprogestogen mifepristone: a review
SK287121B6 (sk) Použitie mezoprogestínov ako farmaceutických komponentov na výrobu liečiva na hormonálnu substitučnú liečbu
US7629334B1 (en) Mesoprogrestins (progesterone receptor modulations) as a component of compositions for hormone replacement therapy (HRT)
ZA200201614B (en) Mesoprogestins (progesterone receptor modulators) as a component of female contraceptives.
CN1450892A (zh) 中孕酮(孕酮受体调节剂)用于治疗和预防激素依赖性良性妇科疾病

Legal Events

Date Code Title Description
TC4A Change of owner's name

Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT, BERL, DE

Effective date: 20091204