SK287190B6 - Spôsob prípravy 9-aminosubstituovaných 9,10-dihydropyrol [2,1-B][1,3] benzodiazepínov - Google Patents

Spôsob prípravy 9-aminosubstituovaných 9,10-dihydropyrol [2,1-B][1,3] benzodiazepínov Download PDF

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Publication number
SK287190B6
SK287190B6 SK126-2003A SK1262003A SK287190B6 SK 287190 B6 SK287190 B6 SK 287190B6 SK 1262003 A SK1262003 A SK 1262003A SK 287190 B6 SK287190 B6 SK 287190B6
Authority
SK
Slovakia
Prior art keywords
compound
acid
amine
formula
reaction
Prior art date
Application number
SK126-2003A
Other languages
English (en)
Slovak (sk)
Other versions
SK1262003A3 (en
Inventor
Patrizia Minetti
Domenico Mastroianni
Original Assignee
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. filed Critical Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Publication of SK1262003A3 publication Critical patent/SK1262003A3/sk
Publication of SK287190B6 publication Critical patent/SK287190B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SK126-2003A 2000-08-01 2001-07-20 Spôsob prípravy 9-aminosubstituovaných 9,10-dihydropyrol [2,1-B][1,3] benzodiazepínov SK287190B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000RM000434A IT1317886B1 (it) 2000-08-01 2000-08-01 Procedimento per la preparazione di 9,10-diidro-pirrolo (2,1-b)(1,3)benzotiazepine 9-ammino sostituite.
PCT/IT2001/000391 WO2002010174A1 (en) 2000-08-01 2001-07-20 Process for the preparation of 9-amino substituted 9,10-dihydropyrrolo [2,1-b][1,3]benzotiazepines

Publications (2)

Publication Number Publication Date
SK1262003A3 SK1262003A3 (en) 2004-03-02
SK287190B6 true SK287190B6 (sk) 2010-02-08

Family

ID=11454867

Family Applications (1)

Application Number Title Priority Date Filing Date
SK126-2003A SK287190B6 (sk) 2000-08-01 2001-07-20 Spôsob prípravy 9-aminosubstituovaných 9,10-dihydropyrol [2,1-B][1,3] benzodiazepínov

Country Status (23)

Country Link
US (1) US7078521B2 (xx)
EP (1) EP1305318B1 (xx)
JP (1) JP2004505089A (xx)
KR (1) KR100801269B1 (xx)
CN (1) CN100354281C (xx)
AT (1) ATE261977T1 (xx)
AU (2) AU2001277687B2 (xx)
BR (1) BR0112974A (xx)
CA (1) CA2415050C (xx)
CZ (1) CZ294502B6 (xx)
DE (1) DE60102385T2 (xx)
DK (1) DK1305318T3 (xx)
ES (1) ES2215922T3 (xx)
HK (1) HK1059775A1 (xx)
HU (2) HUP0301647A3 (xx)
IT (1) IT1317886B1 (xx)
MX (1) MXPA03000917A (xx)
PL (1) PL202400B1 (xx)
PT (1) PT1305318E (xx)
SI (1) SI1305318T1 (xx)
SK (1) SK287190B6 (xx)
TR (1) TR200400821T4 (xx)
WO (1) WO2002010174A1 (xx)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1301965B1 (it) * 1998-07-28 2000-07-20 Sigma Tau Ind Farmaceuti Pirrolo (2,1-b)(1,3) benzotiazepine con attivita' antipsicoticaatipica.

Also Published As

Publication number Publication date
EP1305318B1 (en) 2004-03-17
CN100354281C (zh) 2007-12-12
DK1305318T3 (da) 2004-07-26
CN1443188A (zh) 2003-09-17
US20030181437A1 (en) 2003-09-25
US7078521B2 (en) 2006-07-18
KR20030013525A (ko) 2003-02-14
ES2215922T3 (es) 2004-10-16
EP1305318A1 (en) 2003-05-02
HK1059775A1 (en) 2004-07-16
CA2415050C (en) 2009-10-27
DE60102385D1 (de) 2004-04-22
ITRM20000434A0 (it) 2000-08-01
CA2415050A1 (en) 2002-02-07
CZ294502B6 (cs) 2005-01-12
CZ200311A3 (cs) 2003-05-14
SI1305318T1 (en) 2004-08-31
WO2002010174A1 (en) 2002-02-07
BR0112974A (pt) 2003-07-08
DE60102385T2 (de) 2005-02-17
HUP0301647A2 (hu) 2003-11-28
AU7768701A (en) 2002-02-13
PL365009A1 (en) 2004-12-27
PL202400B1 (pl) 2009-06-30
PT1305318E (pt) 2004-08-31
ITRM20000434A1 (it) 2002-02-01
AU2001277687B2 (en) 2006-10-05
IT1317886B1 (it) 2003-07-15
TR200400821T4 (tr) 2004-07-21
SK1262003A3 (en) 2004-03-02
HUP0301647A3 (en) 2009-08-28
HUP0301648A3 (en) 2004-06-28
JP2004505089A (ja) 2004-02-19
ATE261977T1 (de) 2004-04-15
MXPA03000917A (es) 2003-09-05
KR100801269B1 (ko) 2008-02-04
HUP0301648A2 (hu) 2003-08-28

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20110720