SK287034B6 - Peptidy schopné väzby s oblasťou SH3 proteínu GAP, nukleotidové sekvencie kódujúce tieto peptidy a spôsob ich prípravy a použitie - Google Patents

Peptidy schopné väzby s oblasťou SH3 proteínu GAP, nukleotidové sekvencie kódujúce tieto peptidy a spôsob ich prípravy a použitie Download PDF

Info

Publication number
SK287034B6
SK287034B6 SK629-97A SK62997A SK287034B6 SK 287034 B6 SK287034 B6 SK 287034B6 SK 62997 A SK62997 A SK 62997A SK 287034 B6 SK287034 B6 SK 287034B6
Authority
SK
Slovakia
Prior art keywords
seq
protein
sequences
polypeptide
glu
Prior art date
Application number
SK629-97A
Other languages
English (en)
Slovak (sk)
Other versions
SK62997A3 (en
Inventor
Marc Duchesne
Didier Faucher
Fabienne Parker
Fabien Schweighoffer
Bruno Tocque
Original Assignee
Aventis Pharma S. A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9413955A external-priority patent/FR2727116B1/fr
Priority claimed from FR9505753A external-priority patent/FR2734266B1/fr
Application filed by Aventis Pharma S. A. filed Critical Aventis Pharma S. A.
Publication of SK62997A3 publication Critical patent/SK62997A3/sk
Publication of SK287034B6 publication Critical patent/SK287034B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • C07K14/4706—Guanosine triphosphatase activating protein, GAP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SK629-97A 1994-11-22 1995-11-22 Peptidy schopné väzby s oblasťou SH3 proteínu GAP, nukleotidové sekvencie kódujúce tieto peptidy a spôsob ich prípravy a použitie SK287034B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9413955A FR2727116B1 (fr) 1994-11-22 1994-11-22 Peptides capables de se lier au domaine sh3 de la proteine gap, sequences nucleotidiques codant pour ces peptides, leur preparation et utilisation
FR9505753A FR2734266B1 (fr) 1995-05-16 1995-05-16 Peptides capables de se lier au domaine sh3 de la proteine gap sequences nucleotidiques codant pour ces peptides, leur preparation et utilisation
PCT/FR1995/001539 WO1996016169A1 (fr) 1994-11-22 1995-11-22 Peptides capables de se lier au domaine sh3 de la proteine gap, sequences nucleotidiques codant pour ces peptides, leur preparation et utilisation

Publications (2)

Publication Number Publication Date
SK62997A3 SK62997A3 (en) 1998-02-04
SK287034B6 true SK287034B6 (sk) 2009-10-07

Family

ID=26231549

Family Applications (1)

Application Number Title Priority Date Filing Date
SK629-97A SK287034B6 (sk) 1994-11-22 1995-11-22 Peptidy schopné väzby s oblasťou SH3 proteínu GAP, nukleotidové sekvencie kódujúce tieto peptidy a spôsob ich prípravy a použitie

Country Status (18)

Country Link
US (1) US5886150A (de)
EP (1) EP0793721B1 (de)
JP (2) JPH10509044A (de)
AT (1) ATE305037T1 (de)
AU (1) AU713937B2 (de)
BR (1) BR9510067A (de)
CA (1) CA2204438A1 (de)
CZ (1) CZ292538B6 (de)
DE (1) DE69534471T2 (de)
DK (1) DK0793721T3 (de)
ES (1) ES2248800T3 (de)
FI (1) FI972170A0 (de)
HU (1) HU221410B1 (de)
IL (1) IL116026A (de)
MX (1) MX9703364A (de)
NO (1) NO972313D0 (de)
SK (1) SK287034B6 (de)
WO (1) WO1996016169A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2780062B1 (fr) * 1998-06-17 2000-07-28 Rhone Poulenc Rorer Sa Anticorps monoclonaux diriges contre la proteine g3bp, et leurs utilisations
PT2319928E (pt) 1998-10-23 2013-06-28 Kirin Amgen Inc Péptidos diméricos de trombopoietina que simulam a ligação ao receptor mpl e têm actividade trombopoiética
US6864355B1 (en) 2000-05-02 2005-03-08 Yale University Inhibition of NF-κB activation by blockade of IKKβ-NEMO interactions at the NEMO binding domain
EP1764616B1 (de) * 2000-06-16 2009-04-08 Thomas Dr. Rudel Verfahren zur Identifizierung während der Apoptose modifizierter Proteine
WO2002083846A2 (en) * 2001-04-10 2002-10-24 Children's Medical Center Corporation Methods of analysis and labeling of protein-protein interactions
US20050069999A1 (en) * 2001-07-09 2005-03-31 Sharma Sreenath V Sh3 domain binding inhibitors
WO2003006060A1 (fr) * 2001-07-09 2003-01-23 Kyowa Hakko Kogyo Co., Ltd. Inhibiteurs de la liaison au domaine sh3
AUPR721101A0 (en) * 2001-08-23 2001-09-13 University Of Queensland, The Nucleic acid and polypeptide linked to breast cancer
WO2006010057A2 (en) * 2004-07-08 2006-01-26 Amgen Inc. Therapeutic peptides
CN101103045B (zh) 2004-09-24 2015-11-25 安姆根有限公司 修饰的Fc分子
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
US9283260B2 (en) 2006-04-21 2016-03-15 Amgen Inc. Lyophilized therapeutic peptibody formulations
US11237168B2 (en) * 2019-06-26 2022-02-01 St. Jude Children's Research Hospital Method for identifying modulators of G3BP activity

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA894726B (en) * 1988-06-27 1990-03-28 Akzo Nv Coccidiosis vaccine
JPH05500506A (ja) * 1989-08-21 1993-02-04 カイロン　コーポレイション Ｇｔｐアーゼ活性化タンパク質（ｇａｐ）からのペプチドおよびその診断および治療学的使用
EP0496162A3 (en) * 1990-12-24 1993-09-01 Merck & Co. Inc. Peptide inhibitors of ras-gap interaction
FR2694296B1 (fr) * 1992-07-30 1994-09-02 Rhone Poulenc Rorer Sa Peptides inhibant l'activité des protéines ras, préparation et utilisation.
EP0679185A1 (de) * 1993-01-15 1995-11-02 Schering Corporation Mit ras assoziierte gap-proteine

Also Published As

Publication number Publication date
AU713937B2 (en) 1999-12-16
SK62997A3 (en) 1998-02-04
DE69534471D1 (de) 2006-02-02
EP0793721A1 (de) 1997-09-10
FI972170A (fi) 1997-05-21
WO1996016169A1 (fr) 1996-05-30
IL116026A (en) 2005-08-31
FI972170A0 (fi) 1997-05-21
IL116026A0 (en) 1996-01-31
EP0793721B1 (de) 2005-09-21
HU221410B1 (en) 2002-09-28
CA2204438A1 (fr) 1996-05-30
NO972313L (no) 1997-05-21
JP2006122049A (ja) 2006-05-18
CZ154597A3 (en) 1997-10-15
ATE305037T1 (de) 2005-10-15
HUT77029A (hu) 1998-03-02
US5886150A (en) 1999-03-23
MX9703364A (es) 1997-08-30
CZ292538B6 (cs) 2003-10-15
JPH10509044A (ja) 1998-09-08
NO972313D0 (no) 1997-05-21
DE69534471T2 (de) 2006-06-22
DK0793721T3 (da) 2006-01-30
AU4263696A (en) 1996-06-17
ES2248800T3 (es) 2006-03-16
BR9510067A (pt) 1997-12-30

Similar Documents

Publication Publication Date Title
US5607918A (en) Vascular endothelial growth factor-B and DNA coding therefor
JP3039802B2 (ja) 繊維芽細胞成長因子のための受容体
JP3462498B2 (ja) レセプターチロシンキナーゼ標的タンパク質のｃＤＮＡクローニング方法及びｈＧＲＢタンパク質
JP2006122049A (ja) Ｇａｐタンパク質ｓｈ３ドメインに結合可能なペプチド、それをコードするヌクレオチド配列ならびにその製造法および使用
US7297493B2 (en) Fibroblast growth factor receptor activating gene 1 and related compositions and methods
US5656595A (en) Peptides having GDP exchange factor activity, nucleic acid sequences coding for these peptides, preparation and use
JP2001503984A (ja) Ｒｈｏ―ＧＴＰａｓｅのグアニン交換因子、およびこれをコードする核酸
US7276587B2 (en) Antibodies to EGFH2 polypeptides
JP3907247B2 (ja) Ｔａｂ１蛋白質及びそれをコードするｄｎａ
US6124434A (en) Signal mediator protein that induces cellular morphological alterations
KR100467198B1 (ko) Gap단백질sh3영역에결합가능한펩타이드,이를암호화하는뉴클레오타이드서열,및이들을함유하는약학조성물
EP0948618A1 (de) Menschliches polyhomeotisch 2 (hph2) wirkt wie ein oncogen
US6673911B1 (en) Human polyhomeotic 2 (hph2) acts as an oncogene
AU2006200373B2 (en) Novel tumor supressor encoding nucleic acid, PTX1, and methods of use thereof
WO1999051742A2 (en) Dadd, death activator death domain protein
JPH11290083A (ja) 新規蛋白質
WO2001023423A1 (fr) Nouveau gene comprenant le domaine ww et codant le polypeptide humain interagissant avec l'huntingtine, methode de production dudit gene et application correspondante
WO1999009060A1 (fr) PROTEINE 1(3)mbt, POLYNUCLEOTIDE CODANT POUR LADITE PROTEINE, SON POLYNUCLEOTIDE ANTISENSE ET ANTICORPS RECONNAISSANT LADITE PROTEINE
JP2002500501A (ja) ヒトカルシウムセンサータンパク質、その断片及びそれをコードするｄｎａ

Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20090811