IL116026A - Peptides capable of linking to the sh3 domain of gap, nucleotide sequences encoding the same, their preparation and uses - Google Patents
Peptides capable of linking to the sh3 domain of gap, nucleotide sequences encoding the same, their preparation and usesInfo
- Publication number
- IL116026A IL116026A IL11602695A IL11602695A IL116026A IL 116026 A IL116026 A IL 116026A IL 11602695 A IL11602695 A IL 11602695A IL 11602695 A IL11602695 A IL 11602695A IL 116026 A IL116026 A IL 116026A
- Authority
- IL
- Israel
- Prior art keywords
- domain
- gap
- linking
- preparation
- pct
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
- C07K14/4706—Guanosine triphosphatase activating protein, GAP
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9413955A FR2727116B1 (fr) | 1994-11-22 | 1994-11-22 | Peptides capables de se lier au domaine sh3 de la proteine gap, sequences nucleotidiques codant pour ces peptides, leur preparation et utilisation |
FR9505753A FR2734266B1 (fr) | 1995-05-16 | 1995-05-16 | Peptides capables de se lier au domaine sh3 de la proteine gap sequences nucleotidiques codant pour ces peptides, leur preparation et utilisation |
Publications (2)
Publication Number | Publication Date |
---|---|
IL116026A0 IL116026A0 (en) | 1996-01-31 |
IL116026A true IL116026A (en) | 2005-08-31 |
Family
ID=26231549
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11602695A IL116026A (en) | 1994-11-22 | 1995-11-16 | Peptides capable of linking to the sh3 domain of gap, nucleotide sequences encoding the same, their preparation and uses |
Country Status (18)
Country | Link |
---|---|
US (1) | US5886150A (xx) |
EP (1) | EP0793721B1 (xx) |
JP (2) | JPH10509044A (xx) |
AT (1) | ATE305037T1 (xx) |
AU (1) | AU713937B2 (xx) |
BR (1) | BR9510067A (xx) |
CA (1) | CA2204438A1 (xx) |
CZ (1) | CZ292538B6 (xx) |
DE (1) | DE69534471T2 (xx) |
DK (1) | DK0793721T3 (xx) |
ES (1) | ES2248800T3 (xx) |
FI (1) | FI972170A0 (xx) |
HU (1) | HU221410B1 (xx) |
IL (1) | IL116026A (xx) |
MX (1) | MX9703364A (xx) |
NO (1) | NO972313D0 (xx) |
SK (1) | SK287034B6 (xx) |
WO (1) | WO1996016169A1 (xx) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2780062B1 (fr) * | 1998-06-17 | 2000-07-28 | Rhone Poulenc Rorer Sa | Anticorps monoclonaux diriges contre la proteine g3bp, et leurs utilisations |
PT2319928E (pt) | 1998-10-23 | 2013-06-28 | Kirin Amgen Inc | Péptidos diméricos de trombopoietina que simulam a ligação ao receptor mpl e têm actividade trombopoiética |
US6864355B1 (en) | 2000-05-02 | 2005-03-08 | Yale University | Inhibition of NF-κB activation by blockade of IKKβ-NEMO interactions at the NEMO binding domain |
EP1764616B1 (en) * | 2000-06-16 | 2009-04-08 | Thomas Dr. Rudel | Method for identifying apoptosis modified proteins |
WO2002083846A2 (en) * | 2001-04-10 | 2002-10-24 | Children's Medical Center Corporation | Methods of analysis and labeling of protein-protein interactions |
US20050069999A1 (en) * | 2001-07-09 | 2005-03-31 | Sharma Sreenath V | Sh3 domain binding inhibitors |
WO2003006060A1 (fr) * | 2001-07-09 | 2003-01-23 | Kyowa Hakko Kogyo Co., Ltd. | Inhibiteurs de la liaison au domaine sh3 |
AUPR721101A0 (en) * | 2001-08-23 | 2001-09-13 | University Of Queensland, The | Nucleic acid and polypeptide linked to breast cancer |
WO2006010057A2 (en) * | 2004-07-08 | 2006-01-26 | Amgen Inc. | Therapeutic peptides |
CN101103045B (zh) | 2004-09-24 | 2015-11-25 | 安姆根有限公司 | 修饰的Fc分子 |
US8008453B2 (en) | 2005-08-12 | 2011-08-30 | Amgen Inc. | Modified Fc molecules |
US9283260B2 (en) | 2006-04-21 | 2016-03-15 | Amgen Inc. | Lyophilized therapeutic peptibody formulations |
US11237168B2 (en) * | 2019-06-26 | 2022-02-01 | St. Jude Children's Research Hospital | Method for identifying modulators of G3BP activity |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA894726B (en) * | 1988-06-27 | 1990-03-28 | Akzo Nv | Coccidiosis vaccine |
JPH05500506A (ja) * | 1989-08-21 | 1993-02-04 | カイロン コーポレイション | Gtpアーゼ活性化タンパク質(gap)からのペプチドおよびその診断および治療学的使用 |
EP0496162A3 (en) * | 1990-12-24 | 1993-09-01 | Merck & Co. Inc. | Peptide inhibitors of ras-gap interaction |
FR2694296B1 (fr) * | 1992-07-30 | 1994-09-02 | Rhone Poulenc Rorer Sa | Peptides inhibant l'activité des protéines ras, préparation et utilisation. |
EP0679185A1 (en) * | 1993-01-15 | 1995-11-02 | Schering Corporation | Ras associated gap proteins |
-
1995
- 1995-11-16 IL IL11602695A patent/IL116026A/xx not_active IP Right Cessation
- 1995-11-22 AT AT95941126T patent/ATE305037T1/de not_active IP Right Cessation
- 1995-11-22 BR BR9510067A patent/BR9510067A/pt not_active Application Discontinuation
- 1995-11-22 US US08/836,791 patent/US5886150A/en not_active Expired - Fee Related
- 1995-11-22 CZ CZ19971545A patent/CZ292538B6/cs not_active IP Right Cessation
- 1995-11-22 ES ES95941126T patent/ES2248800T3/es not_active Expired - Lifetime
- 1995-11-22 AU AU42636/96A patent/AU713937B2/en not_active Ceased
- 1995-11-22 MX MX9703364A patent/MX9703364A/es not_active IP Right Cessation
- 1995-11-22 JP JP8516632A patent/JPH10509044A/ja not_active Ceased
- 1995-11-22 CA CA002204438A patent/CA2204438A1/fr not_active Abandoned
- 1995-11-22 DE DE69534471T patent/DE69534471T2/de not_active Expired - Lifetime
- 1995-11-22 DK DK95941126T patent/DK0793721T3/da active
- 1995-11-22 SK SK629-97A patent/SK287034B6/sk not_active IP Right Cessation
- 1995-11-22 HU HU9702079A patent/HU221410B1/hu not_active IP Right Cessation
- 1995-11-22 WO PCT/FR1995/001539 patent/WO1996016169A1/fr active IP Right Grant
- 1995-11-22 EP EP95941126A patent/EP0793721B1/fr not_active Expired - Lifetime
-
1997
- 1997-05-21 NO NO972313A patent/NO972313D0/no not_active Application Discontinuation
- 1997-05-21 FI FI972170A patent/FI972170A0/fi not_active Application Discontinuation
-
2005
- 2005-10-25 JP JP2005309422A patent/JP2006122049A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU713937B2 (en) | 1999-12-16 |
SK62997A3 (en) | 1998-02-04 |
DE69534471D1 (de) | 2006-02-02 |
EP0793721A1 (fr) | 1997-09-10 |
FI972170A (fi) | 1997-05-21 |
WO1996016169A1 (fr) | 1996-05-30 |
FI972170A0 (fi) | 1997-05-21 |
IL116026A0 (en) | 1996-01-31 |
EP0793721B1 (fr) | 2005-09-21 |
HU221410B1 (en) | 2002-09-28 |
CA2204438A1 (fr) | 1996-05-30 |
NO972313L (no) | 1997-05-21 |
JP2006122049A (ja) | 2006-05-18 |
CZ154597A3 (en) | 1997-10-15 |
ATE305037T1 (de) | 2005-10-15 |
HUT77029A (hu) | 1998-03-02 |
US5886150A (en) | 1999-03-23 |
MX9703364A (es) | 1997-08-30 |
CZ292538B6 (cs) | 2003-10-15 |
JPH10509044A (ja) | 1998-09-08 |
NO972313D0 (no) | 1997-05-21 |
DE69534471T2 (de) | 2006-06-22 |
DK0793721T3 (da) | 2006-01-30 |
AU4263696A (en) | 1996-06-17 |
ES2248800T3 (es) | 2006-03-16 |
BR9510067A (pt) | 1997-12-30 |
SK287034B6 (sk) | 2009-10-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |