SK286421B6 - Prostriedok kahalalid F, súprava, rekonštituovanýa zriedený roztok s obsahom tohto prostriedku a použitie - Google Patents

Prostriedok kahalalid F, súprava, rekonštituovanýa zriedený roztok s obsahom tohto prostriedku a použitie Download PDF

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Publication number
SK286421B6
SK286421B6 SK502-2003A SK5022003A SK286421B6 SK 286421 B6 SK286421 B6 SK 286421B6 SK 5022003 A SK5022003 A SK 5022003A SK 286421 B6 SK286421 B6 SK 286421B6
Authority
SK
Slovakia
Prior art keywords
kahalalide
formulation
cancer
reconstituted solution
infusion
Prior art date
Application number
SK502-2003A
Other languages
English (en)
Slovak (sk)
Other versions
SK5022003A3 (en
Inventor
Glynn Thomas Faircloth
Bastian Nuyen
Steve Weitman
Original Assignee
Pharma Mar, S. A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharma Mar, S. A. filed Critical Pharma Mar, S. A.
Publication of SK5022003A3 publication Critical patent/SK5022003A3/sk
Publication of SK286421B6 publication Critical patent/SK286421B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15—Depsipeptides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Liquid Crystal Substances (AREA)
SK502-2003A 2000-10-31 2001-10-31 Prostriedok kahalalid F, súprava, rekonštituovanýa zriedený roztok s obsahom tohto prostriedku a použitie SK286421B6 (sk)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24447100P 2000-10-31 2000-10-31
US24622900P 2000-11-06 2000-11-06
US34844901P 2001-10-19 2001-10-19
PCT/GB2001/004821 WO2002036145A2 (en) 2000-10-31 2001-10-31 Kahalalide f formulation

Publications (2)

Publication Number Publication Date
SK5022003A3 SK5022003A3 (en) 2003-12-02
SK286421B6 true SK286421B6 (sk) 2008-09-05

Family

ID=27399760

Family Applications (1)

Application Number Title Priority Date Filing Date
SK502-2003A SK286421B6 (sk) 2000-10-31 2001-10-31 Prostriedok kahalalid F, súprava, rekonštituovanýa zriedený roztok s obsahom tohto prostriedku a použitie

Country Status (22)

Country Link
US (1) US7473681B2 (cg-RX-API-DMAC7.html)
EP (1) EP1330258B1 (cg-RX-API-DMAC7.html)
JP (2) JP2004512370A (cg-RX-API-DMAC7.html)
KR (1) KR100834138B1 (cg-RX-API-DMAC7.html)
CN (1) CN1568192A (cg-RX-API-DMAC7.html)
AT (1) ATE314084T1 (cg-RX-API-DMAC7.html)
AU (2) AU2002210749B2 (cg-RX-API-DMAC7.html)
BR (1) BR0114912A (cg-RX-API-DMAC7.html)
CA (1) CA2425627A1 (cg-RX-API-DMAC7.html)
CY (1) CY1105009T1 (cg-RX-API-DMAC7.html)
CZ (1) CZ20031211A3 (cg-RX-API-DMAC7.html)
DE (1) DE60116359T2 (cg-RX-API-DMAC7.html)
DK (1) DK1330258T3 (cg-RX-API-DMAC7.html)
ES (1) ES2256305T3 (cg-RX-API-DMAC7.html)
HK (1) HK1054192B (cg-RX-API-DMAC7.html)
HU (1) HUP0600031A3 (cg-RX-API-DMAC7.html)
IL (2) IL155297A0 (cg-RX-API-DMAC7.html)
MX (1) MXPA03003704A (cg-RX-API-DMAC7.html)
NO (1) NO331082B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ525243A (cg-RX-API-DMAC7.html)
SK (1) SK286421B6 (cg-RX-API-DMAC7.html)
WO (1) WO2002036145A2 (cg-RX-API-DMAC7.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0002952D0 (en) * 2000-02-09 2000-03-29 Pharma Mar Sa Process for producing kahalalide F compounds
EP1435990A1 (en) * 2001-10-19 2004-07-14 Pharma Mar, S.A. Kahalalide compounds for use in cancer therapy
US20050054555A1 (en) * 2001-10-19 2005-03-10 Jose Jimeno Kahalalide compounds for use in cancer therapy
DE60335292D1 (de) * 2002-10-18 2011-01-20 Pharma Mar Sau 4-methylhexanoic kahalalide f verbindung
CN101077885A (zh) * 2002-10-18 2007-11-28 马尔药品公司 新型抗肿瘤化合物
GB0304367D0 (en) * 2003-02-26 2003-04-02 Pharma Mar Sau Methods for treating psoriasis
US7507708B2 (en) 2003-02-26 2009-03-24 Pharma Mar, S.A.U. Antitumoral compounds
DE10329847A1 (de) * 2003-07-02 2005-01-20 Toximed Gmbh Pharmazeutischer Wirkstoff gegen Prostatakarzinome
GB0321066D0 (en) * 2003-09-09 2003-10-08 Pharma Mar Sau New antitumoral compounds
GB0408958D0 (en) * 2004-04-22 2004-05-26 Pharma Mar Sa Convergent synthesis for kahalalide compounds
RS50822B (sr) * 2004-10-26 2010-08-31 Pharma Mar S.A., Sociedad Unipersonal Pegilovani lipozomalni doksorubicin u kombinaciji sa ekteinescidinom 743
KR101188691B1 (ko) * 2004-10-29 2012-10-09 파르마 마르 에스.에이. 엑티나시딘 및 디사카라이드를 포함하는 제제
GB0522082D0 (en) * 2005-10-31 2005-12-07 Pharma Mar Sa Formulations
CN101861159A (zh) * 2007-10-19 2010-10-13 马尔药品公司 改进的抗肿瘤治疗
EP2252315A1 (en) * 2008-01-30 2010-11-24 Pharma Mar, S.A. Improved antitumoral treatments
AU2009221120A1 (en) * 2008-03-07 2009-09-11 Pharma Mar, S.A. Improved antitumoral treatments
WO2009135939A2 (en) * 2008-05-09 2009-11-12 Pharma Mar, S.A. Depsipeptide for use in cancer therapy
LT3615544T (lt) 2017-04-27 2023-05-10 Pharma Mar S.A. Priešnavikiniai junginiai

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5037644A (en) * 1986-10-27 1991-08-06 Cetus Corporation Pharmaceutical compositions of recombinant interleukin-2 and formulation processes
JP2799483B2 (ja) 1988-03-09 1998-09-17 大塚製薬株式会社 インターロイキン−1β組成物の安定化方法
GB8819607D0 (en) * 1988-08-17 1988-09-21 Wellcome Found Novel combination
IE64738B1 (en) * 1990-03-20 1995-09-06 Akzo Nv Stabilized gonadotropin containing preparations
JP2971680B2 (ja) 1991-10-02 1999-11-08 山之内製薬株式会社 組織プラスミノーゲン活性化因子含有組成物
JPH0597703A (ja) 1991-10-04 1993-04-20 Yamanouchi Pharmaceut Co Ltd 改変型組織プラスミノーゲン活性化因子含有組成物
US5550124A (en) 1991-12-10 1996-08-27 University Of Southern California Use of peripheral-type benzodiazpine sites for treatment of CNS trauma or disease
US5849704A (en) * 1991-12-20 1998-12-15 Novo Nordisk A/S Pharmaceutical formulation
GB9302046D0 (en) 1993-02-03 1993-03-24 Pharma Mar Sa Antiumoral compound-v
US6274551B1 (en) * 1994-02-03 2001-08-14 Pharmamar, S.A. Cytotoxic and antiviral compound
JP3927248B2 (ja) * 1995-07-11 2007-06-06 第一製薬株式会社 Hgf凍結乾燥製剤
GB9601120D0 (en) 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
JPH1014581A (ja) 1996-07-08 1998-01-20 Morinaga Milk Ind Co Ltd ウサギ型マクロファージ・コロニー刺激因子及びこれをコードするdna断片
DE69719265T2 (de) 1996-09-06 2003-12-04 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute, Kumamoto Medizinische Zusammensetzung die Gewebeplasminogenaktivator und Nikotinamid enthält
JP4025394B2 (ja) * 1996-09-06 2007-12-19 財団法人化学及血清療法研究所 組織プラスミノーゲン活性化因子医薬組成物
GB9803448D0 (en) * 1998-02-18 1998-04-15 Pharma Mar Sa Pharmaceutical formulation
GB9807639D0 (en) 1998-04-14 1998-06-10 Kennedy Rheumatology Inst Anti-inflammatory agents
WO2000016794A1 (en) 1998-09-23 2000-03-30 Marcus Keep Neuroimmunophilins for selective neuronal radioprotection
GB0002952D0 (en) 2000-02-09 2000-03-29 Pharma Mar Sa Process for producing kahalalide F compounds
US20050054555A1 (en) * 2001-10-19 2005-03-10 Jose Jimeno Kahalalide compounds for use in cancer therapy

Also Published As

Publication number Publication date
HUP0600031A2 (en) 2006-05-29
SK5022003A3 (en) 2003-12-02
MXPA03003704A (es) 2004-05-04
CN1568192A (zh) 2005-01-19
ATE314084T1 (de) 2006-01-15
US7473681B2 (en) 2009-01-06
WO2002036145A3 (en) 2002-10-17
EP1330258B1 (en) 2005-12-28
NO20031860D0 (no) 2003-04-25
CY1105009T1 (el) 2010-03-03
US20040067895A1 (en) 2004-04-08
JP2010047601A (ja) 2010-03-04
NZ525243A (en) 2005-01-28
AU2002210749B2 (en) 2006-12-21
PL360848A1 (en) 2004-09-20
HK1054192A1 (en) 2003-11-21
EP1330258A2 (en) 2003-07-30
NO20031860L (no) 2003-06-30
KR20030044005A (ko) 2003-06-02
JP2004512370A (ja) 2004-04-22
DE60116359T2 (de) 2006-09-28
WO2002036145A8 (en) 2003-10-23
IL155297A0 (en) 2003-11-23
HUP0600031A3 (en) 2012-02-28
WO2002036145A2 (en) 2002-05-10
DK1330258T3 (da) 2006-05-22
BR0114912A (pt) 2003-10-14
IL155297A (en) 2010-05-31
NO331082B1 (no) 2011-10-03
ES2256305T3 (es) 2006-07-16
DE60116359D1 (de) 2006-02-02
CA2425627A1 (en) 2002-05-10
KR100834138B1 (ko) 2008-06-02
CZ20031211A3 (cs) 2003-09-17
AU1074902A (en) 2002-05-15
HK1054192B (en) 2006-09-08

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20111031