NO331082B1 - Formulering av kahalalid F, sett omfattende en slik formulering, samt rekonstituert losning derav og anvendelse av en fortynnet rekonstituert losning til fremstilling av et medikament for behandling av kreft - Google Patents
Formulering av kahalalid F, sett omfattende en slik formulering, samt rekonstituert losning derav og anvendelse av en fortynnet rekonstituert losning til fremstilling av et medikament for behandling av kreftInfo
- Publication number
- NO331082B1 NO331082B1 NO20031860A NO20031860A NO331082B1 NO 331082 B1 NO331082 B1 NO 331082B1 NO 20031860 A NO20031860 A NO 20031860A NO 20031860 A NO20031860 A NO 20031860A NO 331082 B1 NO331082 B1 NO 331082B1
- Authority
- NO
- Norway
- Prior art keywords
- formulation
- reconstituted solution
- kahalalide
- medicament
- cancer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/15—Depsipeptides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Liquid Crystal Substances (AREA)
- Superconductors And Manufacturing Methods Therefor (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Carbon And Carbon Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24447100P | 2000-10-31 | 2000-10-31 | |
US24622900P | 2000-11-06 | 2000-11-06 | |
US34844901P | 2001-10-19 | 2001-10-19 | |
PCT/GB2001/004821 WO2002036145A2 (en) | 2000-10-31 | 2001-10-31 | Kahalalide f formulation |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20031860D0 NO20031860D0 (no) | 2003-04-25 |
NO20031860L NO20031860L (no) | 2003-06-30 |
NO331082B1 true NO331082B1 (no) | 2011-10-03 |
Family
ID=27399760
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20031860A NO331082B1 (no) | 2000-10-31 | 2003-04-25 | Formulering av kahalalid F, sett omfattende en slik formulering, samt rekonstituert losning derav og anvendelse av en fortynnet rekonstituert losning til fremstilling av et medikament for behandling av kreft |
Country Status (22)
Country | Link |
---|---|
US (1) | US7473681B2 (no) |
EP (1) | EP1330258B1 (no) |
JP (2) | JP2004512370A (no) |
KR (1) | KR100834138B1 (no) |
CN (1) | CN1568192A (no) |
AT (1) | ATE314084T1 (no) |
AU (2) | AU1074902A (no) |
BR (1) | BR0114912A (no) |
CA (1) | CA2425627A1 (no) |
CY (1) | CY1105009T1 (no) |
CZ (1) | CZ20031211A3 (no) |
DE (1) | DE60116359T2 (no) |
DK (1) | DK1330258T3 (no) |
ES (1) | ES2256305T3 (no) |
HK (1) | HK1054192B (no) |
HU (1) | HUP0600031A3 (no) |
IL (2) | IL155297A0 (no) |
MX (1) | MXPA03003704A (no) |
NO (1) | NO331082B1 (no) |
NZ (1) | NZ525243A (no) |
SK (1) | SK286421B6 (no) |
WO (1) | WO2002036145A2 (no) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0002952D0 (en) | 2000-02-09 | 2000-03-29 | Pharma Mar Sa | Process for producing kahalalide F compounds |
US20050054555A1 (en) * | 2001-10-19 | 2005-03-10 | Jose Jimeno | Kahalalide compounds for use in cancer therapy |
CA2462639A1 (en) * | 2001-10-19 | 2003-04-24 | Pharma Mar, S.A. | Kahalalide compounds for use in cancer therapy |
GB0304367D0 (en) * | 2003-02-26 | 2003-04-02 | Pharma Mar Sau | Methods for treating psoriasis |
DK1572726T3 (da) * | 2002-10-18 | 2011-03-28 | Pharma Mar Sau | 4-methylhexansyre-kahalalid F-forbindelse |
EP1572726B1 (en) * | 2002-10-18 | 2010-12-08 | Pharma Mar, S.A.U. | 4-methylhexanoic kahalalide f compound |
US7507708B2 (en) | 2003-02-26 | 2009-03-24 | Pharma Mar, S.A.U. | Antitumoral compounds |
DE10329847A1 (de) * | 2003-07-02 | 2005-01-20 | Toximed Gmbh | Pharmazeutischer Wirkstoff gegen Prostatakarzinome |
GB0321066D0 (en) | 2003-09-09 | 2003-10-08 | Pharma Mar Sau | New antitumoral compounds |
GB0408958D0 (en) * | 2004-04-22 | 2004-05-26 | Pharma Mar Sa | Convergent synthesis for kahalalide compounds |
ATE430586T1 (de) * | 2004-10-26 | 2009-05-15 | Pharma Mar Sa | Pegyliertes liposomales doxorubicin in kombination mit ecteinescidin 743 |
DK1658848T3 (da) * | 2004-10-29 | 2007-11-26 | Pharma Mar Sa | Formuleringer omfattende ecteinascidin og et disaccharid |
GB0522082D0 (en) * | 2005-10-31 | 2005-12-07 | Pharma Mar Sa | Formulations |
EP2207561A2 (en) * | 2007-10-19 | 2010-07-21 | Pharma Mar, S.A. | Improved antitumoral treatments |
EP2252315A1 (en) * | 2008-01-30 | 2010-11-24 | Pharma Mar, S.A. | Improved antitumoral treatments |
WO2009109649A1 (en) * | 2008-03-07 | 2009-09-11 | Pharma Mar, S.A. | Improved antitumoral treatments |
WO2009135939A2 (en) * | 2008-05-09 | 2009-11-12 | Pharma Mar, S.A. | Depsipeptide for use in cancer therapy |
JOP20190254A1 (ar) | 2017-04-27 | 2019-10-27 | Pharma Mar Sa | مركبات مضادة للأورام |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5037644A (en) * | 1986-10-27 | 1991-08-06 | Cetus Corporation | Pharmaceutical compositions of recombinant interleukin-2 and formulation processes |
JP2799483B2 (ja) | 1988-03-09 | 1998-09-17 | 大塚製薬株式会社 | インターロイキン−1β組成物の安定化方法 |
GB8819607D0 (en) | 1988-08-17 | 1988-09-21 | Wellcome Found | Novel combination |
IE64738B1 (en) * | 1990-03-20 | 1995-09-06 | Akzo Nv | Stabilized gonadotropin containing preparations |
JP2971680B2 (ja) | 1991-10-02 | 1999-11-08 | 山之内製薬株式会社 | 組織プラスミノーゲン活性化因子含有組成物 |
JPH0597703A (ja) | 1991-10-04 | 1993-04-20 | Yamanouchi Pharmaceut Co Ltd | 改変型組織プラスミノーゲン活性化因子含有組成物 |
US5550124A (en) | 1991-12-10 | 1996-08-27 | University Of Southern California | Use of peripheral-type benzodiazpine sites for treatment of CNS trauma or disease |
US5849704A (en) * | 1991-12-20 | 1998-12-15 | Novo Nordisk A/S | Pharmaceutical formulation |
US6274551B1 (en) * | 1994-02-03 | 2001-08-14 | Pharmamar, S.A. | Cytotoxic and antiviral compound |
GB9302046D0 (en) * | 1993-02-03 | 1993-03-24 | Pharma Mar Sa | Antiumoral compound-v |
JP3927248B2 (ja) * | 1995-07-11 | 2007-06-06 | 第一製薬株式会社 | Hgf凍結乾燥製剤 |
GB9601120D0 (en) | 1996-01-19 | 1996-03-20 | Sandoz Ltd | Organic compounds |
JPH1014581A (ja) | 1996-07-08 | 1998-01-20 | Morinaga Milk Ind Co Ltd | ウサギ型マクロファージ・コロニー刺激因子及びこれをコードするdna断片 |
DK0827751T3 (da) | 1996-09-06 | 2003-03-31 | Chemo Sero Therapeut Res Inst | Medicinsk præparat indeholdende vævsplasminogenaktivator og nicotinamid |
JP4025394B2 (ja) * | 1996-09-06 | 2007-12-19 | 財団法人化学及血清療法研究所 | 組織プラスミノーゲン活性化因子医薬組成物 |
GB9803448D0 (en) * | 1998-02-18 | 1998-04-15 | Pharma Mar Sa | Pharmaceutical formulation |
GB9807639D0 (en) | 1998-04-14 | 1998-06-10 | Kennedy Rheumatology Inst | Anti-inflammatory agents |
WO2000016794A1 (en) | 1998-09-23 | 2000-03-30 | Marcus Keep | Neuroimmunophilins for selective neuronal radioprotection |
GB0002952D0 (en) | 2000-02-09 | 2000-03-29 | Pharma Mar Sa | Process for producing kahalalide F compounds |
US20050054555A1 (en) * | 2001-10-19 | 2005-03-10 | Jose Jimeno | Kahalalide compounds for use in cancer therapy |
-
2001
- 2001-10-31 WO PCT/GB2001/004821 patent/WO2002036145A2/en active IP Right Grant
- 2001-10-31 IL IL15529701A patent/IL155297A0/xx unknown
- 2001-10-31 KR KR1020037005347A patent/KR100834138B1/ko not_active IP Right Cessation
- 2001-10-31 JP JP2002538956A patent/JP2004512370A/ja active Pending
- 2001-10-31 AU AU1074902A patent/AU1074902A/xx active Pending
- 2001-10-31 SK SK502-2003A patent/SK286421B6/sk not_active IP Right Cessation
- 2001-10-31 BR BR0114912-1A patent/BR0114912A/pt active Search and Examination
- 2001-10-31 MX MXPA03003704A patent/MXPA03003704A/es active IP Right Grant
- 2001-10-31 ES ES01978654T patent/ES2256305T3/es not_active Expired - Lifetime
- 2001-10-31 DE DE60116359T patent/DE60116359T2/de not_active Expired - Lifetime
- 2001-10-31 CZ CZ20031211A patent/CZ20031211A3/cs unknown
- 2001-10-31 CA CA002425627A patent/CA2425627A1/en not_active Abandoned
- 2001-10-31 DK DK01978654T patent/DK1330258T3/da active
- 2001-10-31 HU HU0600031A patent/HUP0600031A3/hu unknown
- 2001-10-31 CN CNA018182712A patent/CN1568192A/zh active Pending
- 2001-10-31 NZ NZ525243A patent/NZ525243A/en unknown
- 2001-10-31 AU AU2002210749A patent/AU2002210749B2/en not_active Ceased
- 2001-10-31 EP EP01978654A patent/EP1330258B1/en not_active Expired - Lifetime
- 2001-10-31 US US10/399,571 patent/US7473681B2/en not_active Expired - Fee Related
- 2001-10-31 AT AT01978654T patent/ATE314084T1/de active
-
2003
- 2003-04-08 IL IL155297A patent/IL155297A/en not_active IP Right Cessation
- 2003-04-25 NO NO20031860A patent/NO331082B1/no not_active IP Right Cessation
- 2003-09-10 HK HK03106441.9A patent/HK1054192B/zh not_active IP Right Cessation
-
2006
- 2006-03-24 CY CY20061100415T patent/CY1105009T1/el unknown
-
2009
- 2009-10-23 JP JP2009244772A patent/JP2010047601A/ja active Pending
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |