SK286302B6 - Device for emptying cavities containing powder by means of suction - Google Patents
Device for emptying cavities containing powder by means of suction Download PDFInfo
- Publication number
- SK286302B6 SK286302B6 SK1972-2000A SK19722000A SK286302B6 SK 286302 B6 SK286302 B6 SK 286302B6 SK 19722000 A SK19722000 A SK 19722000A SK 286302 B6 SK286302 B6 SK 286302B6
- Authority
- SK
- Slovakia
- Prior art keywords
- suction tube
- blister pack
- carrier
- lid
- cavities
- Prior art date
Links
- 239000000843 powder Substances 0.000 title claims abstract description 14
- 238000005520 cutting process Methods 0.000 claims abstract description 25
- 239000011888 foil Substances 0.000 claims abstract description 23
- 238000003780 insertion Methods 0.000 claims description 32
- 230000037431 insertion Effects 0.000 claims description 32
- 230000033001 locomotion Effects 0.000 claims description 30
- 241000446313 Lamella Species 0.000 claims description 7
- 239000013039 cover film Substances 0.000 claims description 6
- 230000000295 complement effect Effects 0.000 claims description 3
- 238000012546 transfer Methods 0.000 claims description 2
- 230000000903 blocking effect Effects 0.000 description 8
- 230000008901 benefit Effects 0.000 description 7
- 238000006073 displacement reaction Methods 0.000 description 5
- 230000002093 peripheral effect Effects 0.000 description 5
- 239000003814 drug Substances 0.000 description 4
- 230000002349 favourable effect Effects 0.000 description 4
- 239000010408 film Substances 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 239000011324 bead Substances 0.000 description 3
- 238000010276 construction Methods 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 230000001681 protective effect Effects 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 230000004323 axial length Effects 0.000 description 2
- 239000000919 ceramic Substances 0.000 description 2
- 230000001276 controlling effect Effects 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 101100165575 Danio rerio boka gene Proteins 0.000 description 1
- 102000004315 Forkhead Transcription Factors Human genes 0.000 description 1
- 108090000852 Forkhead Transcription Factors Proteins 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 235000019504 cigarettes Nutrition 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 229920001887 crystalline plastic Polymers 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
- A61M15/0023—Mouthpieces therefor retractable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Packages (AREA)
- Catching Or Destruction (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
- Crushing And Pulverization Processes (AREA)
- Basic Packing Technique (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Cosmetics (AREA)
- Dental Preparations (AREA)
- Control And Other Processes For Unpacking Of Materials (AREA)
- Cleaning In General (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19827731 | 1998-06-22 | ||
| DE19830713 | 1998-07-09 | ||
| DE19839516 | 1998-08-29 | ||
| DE19855851A DE19855851A1 (de) | 1998-06-22 | 1998-12-04 | Vorrichtung zum Leersaugen pulverenthaltender Kavitäten |
| PCT/EP1999/004304 WO1999066974A2 (de) | 1998-06-22 | 1999-06-22 | Vorrichtung zum leersaugen pulverenthaltender kavitäten |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK19722000A3 SK19722000A3 (sk) | 2001-07-10 |
| SK286302B6 true SK286302B6 (en) | 2008-07-07 |
Family
ID=27438821
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1972-2000A SK286302B6 (en) | 1998-06-22 | 1999-06-22 | Device for emptying cavities containing powder by means of suction |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6722363B1 (cs) |
| EP (1) | EP1089783B1 (cs) |
| JP (1) | JP4225692B2 (cs) |
| CN (1) | CN100371037C (cs) |
| AT (1) | ATE277658T1 (cs) |
| AU (1) | AU753094B2 (cs) |
| BR (1) | BR9911429A (cs) |
| CA (1) | CA2334950C (cs) |
| CZ (1) | CZ300314B6 (cs) |
| EE (1) | EE04455B1 (cs) |
| ES (1) | ES2228070T3 (cs) |
| HU (1) | HU224243B1 (cs) |
| ID (1) | ID28161A (cs) |
| IL (1) | IL140312A0 (cs) |
| IS (1) | IS2660B (cs) |
| NO (1) | NO20006557D0 (cs) |
| NZ (1) | NZ508618A (cs) |
| PL (1) | PL345363A1 (cs) |
| PT (1) | PT1089783E (cs) |
| SK (1) | SK286302B6 (cs) |
| TR (1) | TR200003856T2 (cs) |
| WO (1) | WO1999066974A2 (cs) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| EP1220698B1 (en) * | 1999-10-12 | 2004-07-21 | SHL Medical AB | Inhaler |
| US6923175B2 (en) | 2002-03-20 | 2005-08-02 | Mannkind Corporation | Inhalation apparatus |
| GR1004350B (el) * | 2002-03-29 | 2003-09-26 | Συσκευη εισπνοων ξηρης σκονης | |
| DE10300032B3 (de) * | 2003-01-03 | 2004-05-27 | E. Braun Gmbh | Pulverinhalator |
| GB2407042B (en) * | 2003-10-17 | 2007-10-24 | Vectura Ltd | Inhaler |
| SE528190C2 (sv) * | 2004-06-07 | 2006-09-19 | Mederio Ag | Inhalator |
| EP1765440A1 (en) * | 2004-06-07 | 2007-03-28 | Mederio AG | Securing dose quality of inhalable drug |
| FR2872798B1 (fr) * | 2004-07-09 | 2007-10-05 | Valois Sas | Ensemble de blisters pour dispositif d'inhalation |
| MX2007001903A (es) | 2004-08-20 | 2007-08-02 | Mannkind Corp | Catalisis de sintesis de dicetopiperazina. |
| KR20150039211A (ko) | 2004-08-23 | 2015-04-09 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
| GB0427028D0 (en) * | 2004-12-09 | 2005-01-12 | Cambridge Consultants | Dry powder inhalers |
| CN101171182A (zh) * | 2005-05-02 | 2008-04-30 | 阿斯利康(瑞典)有限公司 | 用于开启凹部的装置和方法、医用密封包及分配设备 |
| EP1901793A1 (en) * | 2005-07-13 | 2008-03-26 | Cipla Ltd. | Inhaler device |
| EP1928423B1 (en) | 2005-09-14 | 2015-12-09 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces |
| JP5599975B2 (ja) | 2006-02-22 | 2014-10-01 | マンカインド コーポレイション | ジケトピペラジン及び活性薬剤を含有する微粒子の製剤特性の改善方法 |
| GB0621957D0 (en) * | 2006-11-03 | 2006-12-13 | Vectura Group Plc | Inhaler devices and bespoke pharmaceutical compositions |
| EP1992374A1 (en) * | 2007-05-16 | 2008-11-19 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device |
| GB0713876D0 (en) * | 2007-07-18 | 2007-08-29 | 3M Innovative Properties Co | Manufacture of components for medicinal dispensers |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| ES2929343T3 (es) | 2008-06-13 | 2022-11-28 | Mannkind Corp | Inhalador de polvo seco accionado por aspiración para la administración de fármacos |
| CN102065942B (zh) | 2008-06-20 | 2013-12-11 | 曼金德公司 | 用于对吸入工作进行实时描绘的交互式设备和方法 |
| TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| WO2010036788A2 (en) | 2008-09-24 | 2010-04-01 | The General Hospital Corporation | Method and apparatus for grafting of skin tissue |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| EP2210638B1 (en) * | 2009-01-26 | 2013-03-27 | Boehringer Ingelheim International GmbH | Inhaler |
| WO2010105094A1 (en) | 2009-03-11 | 2010-09-16 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| US8551528B2 (en) | 2009-06-12 | 2013-10-08 | Mannkind Corporation | Diketopiperazine microparticles with defined specific surface areas |
| EP2496295A1 (en) | 2009-11-03 | 2012-09-12 | MannKind Corporation | An apparatus and method for simulating inhalation efforts |
| BR112012033060A2 (pt) | 2010-06-21 | 2018-02-27 | Mannkind Corp | métodos de sistema de liberação de fármaco em pó seco |
| CA3078334C (en) | 2011-04-01 | 2022-08-09 | Mannkind Corporation | Blister package for pharmaceutical cartridges |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| CA2852536A1 (en) | 2011-10-24 | 2013-05-02 | Mannkind Corporation | Methods and compositions for treating pain |
| DE102012104850A1 (de) * | 2012-04-05 | 2013-10-10 | Alfred Von Schuckmann | Vorrichtung zur portionierten Ausgabe von Medikamenten |
| CN108057154B (zh) | 2012-07-12 | 2021-04-16 | 曼金德公司 | 干粉药物输送系统和方法 |
| WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
| JP6523247B2 (ja) | 2013-03-15 | 2019-05-29 | マンカインド コーポレイション | 微結晶性ジケトピペラジン粒子の製造方法および乾燥粉末組成物の製造方法 |
| KR102321339B1 (ko) | 2013-07-18 | 2021-11-02 | 맨카인드 코포레이션 | 열-안정성 건조 분말 약제학적 조성물 및 방법 |
| WO2015021064A1 (en) | 2013-08-05 | 2015-02-12 | Mannkind Corporation | Insufflation apparatus and methods |
| WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
| EP3166866B1 (en) | 2014-07-08 | 2019-04-03 | Medipense Inc. | Mechanism for dispensing pills from an array-type package |
| US10065788B2 (en) | 2014-07-08 | 2018-09-04 | Medipense Inc. | Pill dispenser with cylindrical package holder for array-type packages |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| EP3223891B1 (en) * | 2014-11-26 | 2018-09-05 | Vectura Delivery Devices Limited | Blister opening device for dry powder inhaler |
| DE102016119789A1 (de) * | 2016-07-04 | 2018-01-04 | Alfred Von Schuckmann | Vorrichtung zur Ausgabe einer durch Luft austragbaren Substanz |
| JP7126506B2 (ja) | 2017-01-10 | 2022-08-26 | ボストン サイエンティフィック サイムド，インコーポレイテッド | 粉末薬剤を送達するための装置および方法 |
| JP7477719B2 (ja) * | 2020-08-25 | 2024-05-01 | ヴェクトュラ・デリヴァリー・ディヴァイスィズ・リミテッド | 単位用量乾燥粉末吸入器 |
| TWI796680B (zh) * | 2021-04-29 | 2023-03-21 | 宏洋精密工業股份有限公司 | 塑膠部品封包方法及其裝置 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2549303A (en) | 1949-04-20 | 1951-04-17 | Bristol Lab Inc | Inhaler for crystalline pencilllin or the like |
| GB8314308D0 (en) | 1983-05-24 | 1983-06-29 | Matburn Holdings Ltd | Medical administration devices |
| IT1243344B (it) * | 1990-07-16 | 1994-06-10 | Promo Pack Sa | Inalatore plurimonodose per medicamenti in polvere |
| DE4027391A1 (de) | 1990-08-30 | 1992-03-12 | Boehringer Ingelheim Kg | Treibgasfreies inhalationsgeraet |
| US5785049A (en) * | 1994-09-21 | 1998-07-28 | Inhale Therapeutic Systems | Method and apparatus for dispersion of dry powder medicaments |
| DE4239402A1 (de) | 1992-11-24 | 1994-05-26 | Bayer Ag | Pulverinhalator |
| US5343672A (en) | 1992-12-01 | 1994-09-06 | Scherer Ltd R P | Method for manufacturing freeze dried dosages in a multilaminate blister pack |
| US5415162A (en) | 1994-01-18 | 1995-05-16 | Glaxo Inc. | Multi-dose dry powder inhalation device |
| JP3320261B2 (ja) * | 1995-06-01 | 2002-09-03 | 株式会社ユニシアジェックス | 吸入式投薬器 |
| DE19523516C1 (de) * | 1995-06-30 | 1996-10-31 | Asta Medica Ag | Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen |
| PT921830E (pt) * | 1996-04-25 | 2002-12-31 | Astrazeneca Ab | Inalador |
| DE19619536A1 (de) | 1996-04-25 | 1997-10-30 | Alfred Von Schuckmann | Inhalier-Vorrichtung |
| CA2250031C (en) * | 1996-04-25 | 2006-03-28 | Alfred Von Schuckmann | Inhaler |
-
1999
- 1999-06-22 JP JP2000555659A patent/JP4225692B2/ja not_active Expired - Fee Related
- 1999-06-22 BR BR9911429-1A patent/BR9911429A/pt not_active IP Right Cessation
- 1999-06-22 ES ES99932708T patent/ES2228070T3/es not_active Expired - Lifetime
- 1999-06-22 EP EP99932708A patent/EP1089783B1/de not_active Expired - Lifetime
- 1999-06-22 AU AU48999/99A patent/AU753094B2/en not_active Ceased
- 1999-06-22 SK SK1972-2000A patent/SK286302B6/sk not_active IP Right Cessation
- 1999-06-22 CZ CZ20004768A patent/CZ300314B6/cs not_active IP Right Cessation
- 1999-06-22 US US09/719,786 patent/US6722363B1/en not_active Expired - Fee Related
- 1999-06-22 IL IL14031299A patent/IL140312A0/xx active IP Right Grant
- 1999-06-22 PT PT99932708T patent/PT1089783E/pt unknown
- 1999-06-22 HU HU0102534A patent/HU224243B1/hu not_active IP Right Cessation
- 1999-06-22 NZ NZ508618A patent/NZ508618A/en not_active IP Right Cessation
- 1999-06-22 CA CA002334950A patent/CA2334950C/en not_active Expired - Fee Related
- 1999-06-22 PL PL99345363A patent/PL345363A1/xx unknown
- 1999-06-22 TR TR2000/03856T patent/TR200003856T2/xx unknown
- 1999-06-22 EE EEP200000769A patent/EE04455B1/xx not_active IP Right Cessation
- 1999-06-22 AT AT99932708T patent/ATE277658T1/de active
- 1999-06-22 ID IDW20002607A patent/ID28161A/id unknown
- 1999-06-22 CN CNB998077763A patent/CN100371037C/zh not_active Expired - Fee Related
- 1999-06-22 WO PCT/EP1999/004304 patent/WO1999066974A2/de active IP Right Grant
-
2000
- 2000-12-20 IS IS5780A patent/IS2660B/is unknown
- 2000-12-21 NO NO20006557A patent/NO20006557D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PT1089783E (pt) | 2005-01-31 |
| CZ300314B6 (cs) | 2009-04-15 |
| PL345363A1 (en) | 2001-12-17 |
| EP1089783A2 (de) | 2001-04-11 |
| WO1999066974A2 (de) | 1999-12-29 |
| CA2334950A1 (en) | 1999-12-29 |
| NO20006557L (no) | 2000-12-21 |
| EE04455B1 (et) | 2005-04-15 |
| BR9911429A (pt) | 2001-03-20 |
| EE200000769A (et) | 2002-06-17 |
| US6722363B1 (en) | 2004-04-20 |
| HUP0102534A3 (en) | 2001-12-28 |
| ATE277658T1 (de) | 2004-10-15 |
| JP2002518139A (ja) | 2002-06-25 |
| TR200003856T2 (tr) | 2001-06-21 |
| IL140312A0 (en) | 2002-02-10 |
| SK19722000A3 (sk) | 2001-07-10 |
| NZ508618A (en) | 2002-05-31 |
| IS2660B (is) | 2010-08-15 |
| IS5780A (is) | 2000-12-20 |
| EP1089783B1 (de) | 2004-09-29 |
| CA2334950C (en) | 2007-12-04 |
| HUP0102534A2 (hu) | 2001-11-28 |
| ES2228070T3 (es) | 2005-04-01 |
| CN1306447A (zh) | 2001-08-01 |
| AU753094B2 (en) | 2002-10-10 |
| ID28161A (id) | 2001-05-10 |
| CZ20004768A3 (en) | 2001-06-13 |
| HU224243B1 (hu) | 2005-06-28 |
| NO20006557D0 (no) | 2000-12-21 |
| CN100371037C (zh) | 2008-02-27 |
| JP4225692B2 (ja) | 2009-02-18 |
| AU4899999A (en) | 2000-01-10 |
| WO1999066974A3 (de) | 2000-05-04 |
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| MM4A | Patent lapsed due to non-payment of maintenance fees |
Effective date: 20120622 |