SK285128B6 - Liečivý prípravok s riadeným uvoľňovaním obsahujúci tramadol hydrochlorid a spôsob jeho prípravy - Google Patents

Liečivý prípravok s riadeným uvoľňovaním obsahujúci tramadol hydrochlorid a spôsob jeho prípravy Download PDF

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Publication number
SK285128B6
SK285128B6 SK1868-99A SK186899A SK285128B6 SK 285128 B6 SK285128 B6 SK 285128B6 SK 186899 A SK186899 A SK 186899A SK 285128 B6 SK285128 B6 SK 285128B6
Authority
SK
Slovakia
Prior art keywords
weight
amount
controlled release
tramadol hydrochloride
preparation
Prior art date
Application number
SK1868-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK186899A3 (en
Inventor
�Uboslav R�Zus
Helena Sedl�Rov�
Ivan Varga
Ond�Ej Gattnar
Mari�N Zem�Nek
Original Assignee
Zentiva, A. S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentiva, A. S. filed Critical Zentiva, A. S.
Priority to SK1868-99A priority Critical patent/SK285128B6/sk
Priority to TW089125229A priority patent/TWI221419B/zh
Priority to HU0203842A priority patent/HUP0203842A3/hu
Priority to AT00987947T priority patent/ATE324103T1/de
Priority to JP2001548092A priority patent/JP2003518486A/ja
Priority to AU24216/01A priority patent/AU2421601A/en
Priority to CZ20022371A priority patent/CZ297394B6/cs
Priority to DK00987947T priority patent/DK1255535T3/da
Priority to SI200030873T priority patent/SI1255535T1/sl
Priority to PCT/SK2000/000027 priority patent/WO2001047497A2/en
Priority to CA002397942A priority patent/CA2397942C/en
Priority to US10/168,967 priority patent/US20030175343A1/en
Priority to ES00987947T priority patent/ES2266018T3/es
Priority to EA200200720A priority patent/EA006438B1/ru
Priority to DE60027601T priority patent/DE60027601T2/de
Priority to GE4852A priority patent/GEP20053532B/en
Priority to EEP200200368A priority patent/EE05231B1/xx
Priority to EP00987947A priority patent/EP1255535B1/en
Priority to UA2002076286A priority patent/UA76411C2/uk
Priority to PT00987947T priority patent/PT1255535E/pt
Priority to PL357680A priority patent/PL208096B1/pl
Publication of SK186899A3 publication Critical patent/SK186899A3/sk
Priority to LT2002078A priority patent/LT5033B/lt
Priority to BG106952A priority patent/BG65713B1/bg
Priority to LVP-02-137A priority patent/LV12917B/en
Publication of SK285128B6 publication Critical patent/SK285128B6/sk
Priority to CY20061101035T priority patent/CY1106127T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SK1868-99A 1999-12-28 1999-12-28 Liečivý prípravok s riadeným uvoľňovaním obsahujúci tramadol hydrochlorid a spôsob jeho prípravy SK285128B6 (sk)

Priority Applications (25)

Application Number Priority Date Filing Date Title
SK1868-99A SK285128B6 (sk) 1999-12-28 1999-12-28 Liečivý prípravok s riadeným uvoľňovaním obsahujúci tramadol hydrochlorid a spôsob jeho prípravy
TW089125229A TWI221419B (en) 1999-12-28 2000-11-28 Controlled release-pharmaceutical composition containing tramadol hydrochloride and method for its preparation
EA200200720A EA006438B1 (ru) 1999-12-28 2000-12-20 Фармацевтическая композиция с контролируемым высвобождением, содержащая гидрохлорид трамадола, и способ ее получения
GE4852A GEP20053532B (en) 1999-12-28 2000-12-20 Controlled Release Pharmaceutical Composition Containing Tramadol Hydrochloride
JP2001548092A JP2003518486A (ja) 1999-12-28 2000-12-20 トラマドール・ハイドロクロライドを含む放出の調整された医薬組成物およびその調製方法
AU24216/01A AU2421601A (en) 1999-12-28 2000-12-20 Controlled release pharmaceutical composition containing tramadol hydrochloride and method for its preparation
CZ20022371A CZ297394B6 (cs) 1999-12-28 2000-12-20 Lécivý prípravek s rízeným uvolnováním obsahujícítramadol hydrochlorid a zpusob jeho prípravy
DK00987947T DK1255535T3 (da) 1999-12-28 2000-12-20 Lægemiddelsammensætning med kontrolleret frisætning indeholdende tramadol-hydrochlorid
SI200030873T SI1255535T1 (sl) 1999-12-28 2000-12-20 Farmacevtski sestavek s kontroliranim sproscanjem, ki vsebuje tramadol hidroklorid
PCT/SK2000/000027 WO2001047497A2 (en) 1999-12-28 2000-12-20 Controlled release pharmaceutical composition containing tramadol hydrochloride
CA002397942A CA2397942C (en) 1999-12-28 2000-12-20 Controlled release pharmaceutical composition containing tramadol hydrochloride and method for its preparation
US10/168,967 US20030175343A1 (en) 1999-12-28 2000-12-20 Controlled release pharmaceutical composition containing tramadol hydrochloride
ES00987947T ES2266018T3 (es) 1999-12-28 2000-12-20 Composicion farmaceutica de liberacion controlada, que contiene hidrocloruro de tramadol.
HU0203842A HUP0203842A3 (en) 1999-12-28 2000-12-20 Controlled release pharmaceutical composition containing tramadol hydrochloride and method for its preparation
DE60027601T DE60027601T2 (de) 1999-12-28 2000-12-20 Arzneizubereitung mit kontrollierter freisetzung enthaltend tramadol hydrochlorid
AT00987947T ATE324103T1 (de) 1999-12-28 2000-12-20 Arzneizubereitung mit kontrollierter freisetzung enthaltend tramadol hydrochlorid
EEP200200368A EE05231B1 (et) 1999-12-28 2000-12-20 Tramadoolvesinikkloriidi sisaldav toimeainet reguleeritult vabastav ravimkoostis ja meetod selle valmistamiseks
EP00987947A EP1255535B1 (en) 1999-12-28 2000-12-20 Controlled release pharmaceutical composition containing tramadol hydrochloride
UA2002076286A UA76411C2 (en) 1999-12-28 2000-12-20 Controlled release pharmaceutical composition containing tramadol hydrochloride and method for its preparation
PT00987947T PT1255535E (pt) 1999-12-28 2000-12-20 Composicao farmaceutica de libertacao controlada contendo cloridrato de tramadol
PL357680A PL208096B1 (pl) 1999-12-28 2000-12-20 Kompozycja farmaceutyczna o kontrolowanym uwalnianiu zawierająca chlorowodorek tramadolu i sposób jej wytwarzania
LT2002078A LT5033B (lt) 1999-12-28 2002-07-02 Kontroliuojamo išsiskyrimo farmacinė kompozicija, turinti tramadolo hidrochlorido, ir jos paruošimo būdas
BG106952A BG65713B1 (bg) 1999-12-28 2002-07-25 Фармацевтичен състав с контролирано освобождаване, съдържащ трамадол хидрохлорид, и метод за неговото получаване
LVP-02-137A LV12917B (en) 1999-12-28 2002-07-26 Controlled release pharmaceutical composition containing tramadol hydrochloride and method for its preparation
CY20061101035T CY1106127T1 (el) 1999-12-28 2006-07-26 Φαρμακευτικη συσταση ελεγχομενης αποδεσμευσης που πepιεχει υδροχλωρικη τραμαδολη

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SK1868-99A SK285128B6 (sk) 1999-12-28 1999-12-28 Liečivý prípravok s riadeným uvoľňovaním obsahujúci tramadol hydrochlorid a spôsob jeho prípravy

Publications (2)

Publication Number Publication Date
SK186899A3 SK186899A3 (en) 2001-07-10
SK285128B6 true SK285128B6 (sk) 2006-07-07

Family

ID=20434830

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1868-99A SK285128B6 (sk) 1999-12-28 1999-12-28 Liečivý prípravok s riadeným uvoľňovaním obsahujúci tramadol hydrochlorid a spôsob jeho prípravy

Country Status (25)

Country Link
US (1) US20030175343A1 (pt)
EP (1) EP1255535B1 (pt)
JP (1) JP2003518486A (pt)
AT (1) ATE324103T1 (pt)
AU (1) AU2421601A (pt)
BG (1) BG65713B1 (pt)
CA (1) CA2397942C (pt)
CY (1) CY1106127T1 (pt)
CZ (1) CZ297394B6 (pt)
DE (1) DE60027601T2 (pt)
DK (1) DK1255535T3 (pt)
EA (1) EA006438B1 (pt)
EE (1) EE05231B1 (pt)
ES (1) ES2266018T3 (pt)
GE (1) GEP20053532B (pt)
HU (1) HUP0203842A3 (pt)
LT (1) LT5033B (pt)
LV (1) LV12917B (pt)
PL (1) PL208096B1 (pt)
PT (1) PT1255535E (pt)
SI (1) SI1255535T1 (pt)
SK (1) SK285128B6 (pt)
TW (1) TWI221419B (pt)
UA (1) UA76411C2 (pt)
WO (1) WO2001047497A2 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050182056A9 (en) * 2002-02-21 2005-08-18 Seth Pawan Modified release formulations of at least one form of tramadol
US8128957B1 (en) 2002-02-21 2012-03-06 Valeant International (Barbados) Srl Modified release compositions of at least one form of tramadol
SK286107B6 (sk) * 2002-04-12 2008-03-05 Zentiva, A. S. Analgeticky účinný perorálny liečivý prípravok s kontrolovaným uvoľňovaním opioidnej účinnej látky a spôsob jeho prípravy
DE10245623A1 (de) * 2002-09-30 2004-04-08 Clariant Gmbh Ester und Partialester aus mehrwertigen Alkoholen
EP1651248B1 (en) * 2003-07-11 2009-09-09 Novartis AG Orally dosed pharmaceutical compositions comprising a delivery agent in micronized form
US20100143573A1 (en) * 2006-06-09 2010-06-10 John Godber Mineral fortification substance for clear beverages
BRPI0712181A2 (pt) * 2006-06-09 2012-01-17 Innophos Inc substáncia de fortificação com cálcio para bebidas claras
DE102006044694A1 (de) * 2006-09-22 2008-03-27 Krewel Meuselbach Gmbh Perorale feste Schmerzmittelzubereitung
US20100003322A1 (en) * 2008-07-03 2010-01-07 Lai Felix S Enteric coated hydrophobic matrix formulation
EP2919903B1 (en) 2012-11-14 2020-07-22 W.R. Grace & CO. - CONN. Compositions containing a biologically active material and a non-ordered inorganic oxide

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ260408A (en) 1993-05-10 1996-05-28 Euro Celtique Sa Controlled release preparation comprising tramadol
DE4329794C2 (de) * 1993-09-03 1997-09-18 Gruenenthal Gmbh Tramadolsalz enthaltende Arzneimittel mit verzögerter Wirkstofffreisetzung
EP0654263B1 (en) 1993-11-23 2002-01-23 Euro-Celtique S.A. Method for preparing a sustained release composition
DE4343993A1 (de) * 1993-12-22 1995-06-29 Stockhausen Chem Fab Gmbh Pfropf-Copolymerisate von ungesättigten Monomeren und Polyhydroxyverbindungen, Verfahren zu ihrer Herstellung und ihre Verwendung
FR2753904B1 (fr) * 1996-10-01 1998-10-30 Gattefosse Ets Sa Composition pharmaceutique a liberation modifiee de principe actif, comportant une matrice, et procede de fabrication
US5980941A (en) * 1997-08-20 1999-11-09 Fuisz Technologies Ltd. Self-binding shearform compositions
DE19901683B4 (de) * 1999-01-18 2005-07-21 Grünenthal GmbH Analgetikum mit kontrollierter Wirkstofffreisetzung
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions

Also Published As

Publication number Publication date
HUP0203842A3 (en) 2004-06-28
EA006438B1 (ru) 2005-12-29
UA76411C2 (en) 2006-08-15
SI1255535T1 (sl) 2006-10-31
SK186899A3 (en) 2001-07-10
DE60027601T2 (de) 2007-04-26
EE05231B1 (et) 2009-12-15
CY1106127T1 (el) 2011-06-08
US20030175343A1 (en) 2003-09-18
CZ20022371A3 (cs) 2002-10-16
CA2397942C (en) 2008-07-15
DK1255535T3 (da) 2006-08-28
GEP20053532B (en) 2005-05-25
BG65713B1 (bg) 2009-08-31
EP1255535A2 (en) 2002-11-13
LV12917B (en) 2003-02-20
EP1255535B1 (en) 2006-04-26
AU2421601A (en) 2001-07-09
LT5033B (lt) 2003-07-25
ATE324103T1 (de) 2006-05-15
DE60027601D1 (de) 2006-06-01
CA2397942A1 (en) 2001-07-05
EA200200720A1 (ru) 2003-02-27
JP2003518486A (ja) 2003-06-10
CZ297394B6 (cs) 2006-12-13
WO2001047497A2 (en) 2001-07-05
LT2002078A (en) 2003-03-25
TWI221419B (en) 2004-10-01
PL208096B1 (pl) 2011-03-31
WO2001047497A3 (en) 2002-09-12
EE200200368A (et) 2003-10-15
HUP0203842A2 (hu) 2003-05-28
ES2266018T3 (es) 2007-03-01
BG106952A (en) 2003-03-31
PL357680A1 (en) 2004-07-26
PT1255535E (pt) 2006-09-29

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Legal Events

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MK4A Expiry of patent

Expiry date: 20191228