SK284879B6 - Polypeptidy so schopnosťou tvorby väzbových štruktúr na antigén so špecificitou pre Rhesus D antigény, DNA kódujúce také polypeptidy, spôsob ich prípravy a použitie - Google Patents

Polypeptidy so schopnosťou tvorby väzbových štruktúr na antigén so špecificitou pre Rhesus D antigény, DNA kódujúce také polypeptidy, spôsob ich prípravy a použitie Download PDF

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Publication number
SK284879B6
SK284879B6 SK1761-98A SK176198A SK284879B6 SK 284879 B6 SK284879 B6 SK 284879B6 SK 176198 A SK176198 A SK 176198A SK 284879 B6 SK284879 B6 SK 284879B6
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SK
Slovakia
Prior art keywords
ser
gly
thr
leu
ala
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Application number
SK1761-98A
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English (en)
Slovak (sk)
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SK176198A3 (en
Inventor
Sylvia Miescher
Monique Vogel
Beda Stadler
Andreas Morell
Martin Imboden
Hanspeter Amstutz
Original Assignee
Zlb Behring Ag
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Application filed by Zlb Behring Ag filed Critical Zlb Behring Ag
Publication of SK176198A3 publication Critical patent/SK176198A3/sk
Publication of SK284879B6 publication Critical patent/SK284879B6/sk

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/80—Antibody or fragment thereof whose amino acid sequence is disclosed in whole or in part
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
SK1761-98A 1996-06-24 1997-06-20 Polypeptidy so schopnosťou tvorby väzbových štruktúr na antigén so špecificitou pre Rhesus D antigény, DNA kódujúce také polypeptidy, spôsob ich prípravy a použitie SK284879B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96810421 1996-06-24
PCT/EP1997/003253 WO1997049809A1 (en) 1996-06-24 1997-06-20 Polypeptides capable of forming antigen binding structures with specificity for the rhesus d antigens, the dna encoding them and the process for their preparation and use

Publications (2)

Publication Number Publication Date
SK176198A3 SK176198A3 (en) 1999-07-12
SK284879B6 true SK284879B6 (sk) 2006-01-05

Family

ID=8225636

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1761-98A SK284879B6 (sk) 1996-06-24 1997-06-20 Polypeptidy so schopnosťou tvorby väzbových štruktúr na antigén so špecificitou pre Rhesus D antigény, DNA kódujúce také polypeptidy, spôsob ich prípravy a použitie

Country Status (23)

Country Link
US (3) US7038020B1 (no)
EP (1) EP0920509B1 (no)
JP (1) JP3841360B2 (no)
KR (1) KR100361449B1 (no)
AT (1) ATE272116T1 (no)
AU (1) AU722127B2 (no)
BG (1) BG64534B1 (no)
BR (1) BR9709958A (no)
CA (1) CA2258494C (no)
CZ (1) CZ296807B6 (no)
DE (1) DE69730031T2 (no)
DK (1) DK0920509T3 (no)
ES (1) ES2224255T3 (no)
HU (1) HUP9902605A3 (no)
IL (1) IL127595A (no)
IS (1) IS2220B (no)
NO (1) NO327947B1 (no)
NZ (1) NZ333329A (no)
PL (1) PL186019B1 (no)
RU (1) RU2204602C2 (no)
SK (1) SK284879B6 (no)
TR (1) TR199802692T2 (no)
WO (1) WO1997049809A1 (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000029583A2 (en) * 1998-11-19 2000-05-25 Incyte Pharmaceuticals, Inc. Immunoglobulin superfamily proteins
EP1106625A1 (en) * 1999-11-17 2001-06-13 ZLB Bioplasma AG Rhesus D specific peptide sequences
FR2807767B1 (fr) 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
DK1276855T3 (da) * 2000-04-17 2012-11-26 Dyax Corp Fremgangsmåde til konstruktion af visningsbiblioteker over genetiske pakker for medlemmer af en diversificeret peptidfamilie
US8288322B2 (en) 2000-04-17 2012-10-16 Dyax Corp. Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
WO2002046435A2 (en) * 2000-12-05 2002-06-13 Alexion Pharmaceuticals, Inc. Engineered plasmids and their use for in situ production of genes
DE60144063D1 (de) 2000-12-18 2011-03-31 Dyax Corp Gerichtete bibliotheken die genetisch verpackt sind
AU2016225923B2 (en) * 2001-04-17 2018-07-05 Takeda Pharmaceutical Company Limited Novel Methods of Constructing Libraries Comprising Displayed and/or Expressed Members of a Diverse Family of Peptides, Polypeptides or Proteins and the Novel Libraries
US20040067532A1 (en) 2002-08-12 2004-04-08 Genetastix Corporation High throughput generation and affinity maturation of humanized antibody
WO2006007850A1 (en) 2004-07-20 2006-01-26 Symphogen A/S Anti-rhesus d recombinant polyclonal antibody and methods of manufacture
ATE443870T1 (de) 2004-07-20 2009-10-15 Symphogen As Verfahren zur charakterisierung einer polyklonalen zellinie
GB0706558D0 (en) * 2007-04-03 2007-05-09 Common Services Agency For The Diagnostic assay
EP3753947A1 (en) 2007-09-14 2020-12-23 Adimab, LLC Rationally designed, synthetic antibody libraries and uses therefor
US8877688B2 (en) 2007-09-14 2014-11-04 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
US20090093004A1 (en) 2007-10-04 2009-04-09 Symphogen A/S Potency assay
WO2009114815A1 (en) 2008-03-13 2009-09-17 Dyax Corp Libraries of genetic packages comprising novel hc cdr3 designs
CA2968164C (en) 2008-04-24 2019-08-20 Dyax Corp. Libraries of genetic packages comprising novel hc cdr1, cdr2, and cdr3 and novel lc cdr1, cdr2, and cdr3 designs
CN103282560B (zh) 2010-07-16 2016-08-03 阿迪马布有限责任公司 抗体文库
JP2015535005A (ja) * 2012-11-06 2015-12-07 メディミューン，エルエルシー 抗シュードモナス属（Ｐｓｅｕｄｏｍｏｎａｓ）ＰｓｌおよびＰｃｒＶ結合分子を用いた併用治療
AU2018350372A1 (en) * 2017-10-20 2020-04-30 Csl Limited Method

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2127434A (en) 1982-09-17 1984-04-11 Univ London A human monoclonal antibody against Rhesus D antigen
GB8925590D0 (en) * 1989-11-13 1990-01-04 Central Blood Lab Authority Monoclonal antibodies

Also Published As

Publication number Publication date
SK176198A3 (en) 1999-07-12
PL330794A1 (en) 1999-06-07
ATE272116T1 (de) 2004-08-15
NO986088D0 (no) 1998-12-23
CA2258494C (en) 2008-05-27
WO1997049809A1 (en) 1997-12-31
US7429647B2 (en) 2008-09-30
BR9709958A (pt) 1999-08-10
US20050266013A1 (en) 2005-12-01
JP2000515732A (ja) 2000-11-28
AU722127B2 (en) 2000-07-20
HUP9902605A2 (hu) 1999-11-29
US7399471B2 (en) 2008-07-15
NO327947B1 (no) 2009-10-26
IS2220B (is) 2007-03-15
JP3841360B2 (ja) 2006-11-01
NO986088L (no) 1999-02-24
IS4922A (is) 1998-12-11
ES2224255T3 (es) 2005-03-01
KR20000022530A (ko) 2000-04-25
CA2258494A1 (en) 1997-12-31
CZ296807B6 (cs) 2006-06-14
US20060165694A1 (en) 2006-07-27
DE69730031D1 (de) 2004-09-02
EP0920509A1 (en) 1999-06-09
BG103016A (en) 1999-08-31
US7038020B1 (en) 2006-05-02
BG64534B1 (bg) 2005-06-30
EP0920509B1 (en) 2004-07-28
KR100361449B1 (ko) 2003-01-24
HUP9902605A3 (en) 2001-11-28
DE69730031T2 (de) 2005-06-16
IL127595A (en) 2005-09-25
NZ333329A (en) 2000-07-28
IL127595A0 (en) 1999-10-28
AU3342397A (en) 1998-01-14
PL186019B1 (pl) 2003-09-30
TR199802692T2 (xx) 1999-03-22
DK0920509T3 (da) 2004-12-06
CZ395998A3 (cs) 1999-05-12
RU2204602C2 (ru) 2003-05-20

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MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20120620