IL127595A - Polypeptides capable of forming antigen binding structures with specificity for the rhesus d antigens, the dna encoding them and the process for their preparation and use - Google Patents

Polypeptides capable of forming antigen binding structures with specificity for the rhesus d antigens, the dna encoding them and the process for their preparation and use

Info

Publication number
IL127595A
IL127595A IL12759597A IL12759597A IL127595A IL 127595 A IL127595 A IL 127595A IL 12759597 A IL12759597 A IL 12759597A IL 12759597 A IL12759597 A IL 12759597A IL 127595 A IL127595 A IL 127595A
Authority
IL
Israel
Prior art keywords
rhesus
preparation
antigen binding
antigens
specificity
Prior art date
Application number
IL12759597A
Other languages
English (en)
Other versions
IL127595A0 (en
Original Assignee
Zlb Behring Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zlb Behring Ag filed Critical Zlb Behring Ag
Publication of IL127595A0 publication Critical patent/IL127595A0/xx
Publication of IL127595A publication Critical patent/IL127595A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/80—Antibody or fragment thereof whose amino acid sequence is disclosed in whole or in part
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
IL12759597A 1996-06-24 1997-06-20 Polypeptides capable of forming antigen binding structures with specificity for the rhesus d antigens, the dna encoding them and the process for their preparation and use IL127595A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96810421 1996-06-24
PCT/EP1997/003253 WO1997049809A1 (en) 1996-06-24 1997-06-20 Polypeptides capable of forming antigen binding structures with specificity for the rhesus d antigens, the dna encoding them and the process for their preparation and use

Publications (2)

Publication Number Publication Date
IL127595A0 IL127595A0 (en) 1999-10-28
IL127595A true IL127595A (en) 2005-09-25

Family

ID=8225636

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12759597A IL127595A (en) 1996-06-24 1997-06-20 Polypeptides capable of forming antigen binding structures with specificity for the rhesus d antigens, the dna encoding them and the process for their preparation and use

Country Status (23)

Country Link
US (3) US7038020B1 (no)
EP (1) EP0920509B1 (no)
JP (1) JP3841360B2 (no)
KR (1) KR100361449B1 (no)
AT (1) ATE272116T1 (no)
AU (1) AU722127B2 (no)
BG (1) BG64534B1 (no)
BR (1) BR9709958A (no)
CA (1) CA2258494C (no)
CZ (1) CZ296807B6 (no)
DE (1) DE69730031T2 (no)
DK (1) DK0920509T3 (no)
ES (1) ES2224255T3 (no)
HU (1) HUP9902605A3 (no)
IL (1) IL127595A (no)
IS (1) IS2220B (no)
NO (1) NO327947B1 (no)
NZ (1) NZ333329A (no)
PL (1) PL186019B1 (no)
RU (1) RU2204602C2 (no)
SK (1) SK284879B6 (no)
TR (1) TR199802692T2 (no)
WO (1) WO1997049809A1 (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1131428A2 (en) * 1998-11-19 2001-09-12 Incyte Pharmaceuticals, Inc. Immunoglobulin superfamily proteins
EP1106625A1 (en) * 1999-11-17 2001-06-13 ZLB Bioplasma AG Rhesus D specific peptide sequences
FR2807767B1 (fr) * 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
US8288322B2 (en) 2000-04-17 2012-10-16 Dyax Corp. Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
AU2001253589B2 (en) * 2000-04-17 2007-08-16 Dyax Corp Methods of constructing display libraries of genetic packages for members of a diverse family of peptides
AU2002226049A1 (en) * 2000-12-05 2002-06-18 Alexion Pharmaceuticals, Inc. Engineered plasmids and their use for in situ production of genes
US20030119056A1 (en) 2000-12-18 2003-06-26 Ladner Robert Charles Focused libraries of genetic packages
AU2016225923B2 (en) * 2001-04-17 2018-07-05 Takeda Pharmaceutical Company Limited Novel Methods of Constructing Libraries Comprising Displayed and/or Expressed Members of a Diverse Family of Peptides, Polypeptides or Proteins and the Novel Libraries
US20040067532A1 (en) 2002-08-12 2004-04-08 Genetastix Corporation High throughput generation and affinity maturation of humanized antibody
RU2426795C2 (ru) 2004-07-20 2011-08-20 Симфоген А/С Способ структурной характеристики рекомбинантного поликлонального белка или поликлональной клеточной линии
CA2574062A1 (en) * 2004-07-20 2006-01-26 Symphogen A/S Anti-rhesus d recombinant polyclonal antibody and methods of manufacture
GB0706558D0 (en) * 2007-04-03 2007-05-09 Common Services Agency For The Diagnostic assay
BRPI0816785A2 (pt) 2007-09-14 2017-05-02 Adimab Inc bibliotecas de anticorpos sintéticos racionalmente desenhadas, e, usos para as mesmas
US8877688B2 (en) 2007-09-14 2014-11-04 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
US20090093004A1 (en) 2007-10-04 2009-04-09 Symphogen A/S Potency assay
US9873957B2 (en) 2008-03-13 2018-01-23 Dyax Corp. Libraries of genetic packages comprising novel HC CDR3 designs
CA2968164C (en) 2008-04-24 2019-08-20 Dyax Corp. Libraries of genetic packages comprising novel hc cdr1, cdr2, and cdr3 and novel lc cdr1, cdr2, and cdr3 designs
KR102024922B1 (ko) 2010-07-16 2019-09-25 아디맵 엘엘씨 항체 라이브러리
EP2917236A2 (en) * 2012-11-06 2015-09-16 MedImmune, LLC Combination therapies using anti-pseudomonas psl and pcrv binding molecules
WO2019075523A1 (en) * 2017-10-20 2019-04-25 Csl Ltd. PROCESS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2127434A (en) 1982-09-17 1984-04-11 Univ London A human monoclonal antibody against Rhesus D antigen
GB8925590D0 (en) 1989-11-13 1990-01-04 Central Blood Lab Authority Monoclonal antibodies

Also Published As

Publication number Publication date
ATE272116T1 (de) 2004-08-15
BG103016A (en) 1999-08-31
AU3342397A (en) 1998-01-14
DK0920509T3 (da) 2004-12-06
NO327947B1 (no) 2009-10-26
BR9709958A (pt) 1999-08-10
IS4922A (is) 1998-12-11
IL127595A0 (en) 1999-10-28
HUP9902605A2 (hu) 1999-11-29
EP0920509A1 (en) 1999-06-09
CZ296807B6 (cs) 2006-06-14
KR100361449B1 (ko) 2003-01-24
JP2000515732A (ja) 2000-11-28
PL186019B1 (pl) 2003-09-30
US20060165694A1 (en) 2006-07-27
NO986088D0 (no) 1998-12-23
PL330794A1 (en) 1999-06-07
EP0920509B1 (en) 2004-07-28
HUP9902605A3 (en) 2001-11-28
RU2204602C2 (ru) 2003-05-20
ES2224255T3 (es) 2005-03-01
CA2258494C (en) 2008-05-27
IS2220B (is) 2007-03-15
US7038020B1 (en) 2006-05-02
NZ333329A (en) 2000-07-28
KR20000022530A (ko) 2000-04-25
WO1997049809A1 (en) 1997-12-31
TR199802692T2 (xx) 1999-03-22
DE69730031T2 (de) 2005-06-16
AU722127B2 (en) 2000-07-20
BG64534B1 (bg) 2005-06-30
US7429647B2 (en) 2008-09-30
SK284879B6 (sk) 2006-01-05
US20050266013A1 (en) 2005-12-01
US7399471B2 (en) 2008-07-15
CZ395998A3 (cs) 1999-05-12
JP3841360B2 (ja) 2006-11-01
CA2258494A1 (en) 1997-12-31
DE69730031D1 (de) 2004-09-02
NO986088L (no) 1999-02-24
SK176198A3 (en) 1999-07-12

Similar Documents

Publication Publication Date Title
IL127595A0 (en) Polypeptides capable of forming antigen binding structures with specificity for the rhesus D antigens the DNA encoding them and the process for their preparation and use
WO1998050547A3 (en) Human toll-like receptor proteins, related reagents and methods
EP0651818A4 (en) IMMUNOGENIC PEPTIDES, ANTIBODIES AND USES THEREOF IN CONNECTION WITH THE BINDING OF THE CD4 MOLECULE RECEPTOR.
UA29494C2 (uk) Гуманізовані антитіла, способи їх продукування, спосіб лікування хвороби крона, спосіб лікування розсіяного склерозу, фармацевтична композиція
HK1012841A1 (en) Pharmaceutical composition for the treatment or prevention of amalignant tumor
AU4230493A (en) Diphtheria toxin receptor-binding region
BG104149A (en) Interleukin-18-binding proteins, methods for their preparation and administration
HK166495A (en) HIV-1 envelope muteins lacking hypervariable domains
IL138424A (en) Covalently reactive antigen analogs and pharmaceutical compositions containing the same
WO1997008318A3 (en) Compounds and methods for treatment and diagnosis of prostate cancer
IE890853L (en) Monoclonal Antibodies
AU6832398A (en) Multiple antigen glycopeptide carbohydrate, vaccine comprising the same and use thereof
CA2068222A1 (en) Monoclonal antibodies
WO1996021734A3 (en) P15 and tyrosinase melanoma antigens and their use in diagnostic and therapeutic methods
EP1433792A8 (en) Human receptor proteins, related reagents and methods
WO2003003986A3 (en) Parathyroid hormone antibodies and related methods
WO2001057219A3 (en) Mammalian interleukin-1-delta and -epsilon. their use in therapeutic and diagnostic methods
EP0177814A3 (en) Peptide antibodies and their use in detecting oncogene products
AU641736B2 (en) Delivery of agents
WO2002051237A3 (en) Helicobacter proteins, nucleic acids and uses thereof
WO1999019480A3 (en) Human receptor proteins; related reagents and methods
WO2000017363A3 (en) Interleukin-1 like molecule: interleukin-1-zeta; nucleic acids, polypeptides, antibodies, their uses
ES2092960A1 (es) Gen de la proteina 1 de union a transferrina (tbp1) de actinobacillus pleuropneumoniae, utilizacion de esta en la preparacion de productos para la vacunacion contra la pleuroneumonia y en reactivos de diagnostico.

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees