SK284263B6 - Perorálny prípravok s oneskoreným pulzným uvoľňovaním a spôsob jeho prípravy - Google Patents

Perorálny prípravok s oneskoreným pulzným uvoľňovaním a spôsob jeho prípravy Download PDF

Info

Publication number
SK284263B6
SK284263B6 SK376-99A SK37699A SK284263B6 SK 284263 B6 SK284263 B6 SK 284263B6 SK 37699 A SK37699 A SK 37699A SK 284263 B6 SK284263 B6 SK 284263B6
Authority
SK
Slovakia
Prior art keywords
release
oral
delayed
core
formulation
Prior art date
Application number
SK376-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK37699A3 (en
Inventor
Balken Paulus Maria Van
Jules Alex Cornelis Elbers
Henderik Willem Frijlink
Wienman Emerald Philips
Original Assignee
Duphar International Research B. V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar International Research B. V. filed Critical Duphar International Research B. V.
Publication of SK37699A3 publication Critical patent/SK37699A3/sk
Publication of SK284263B6 publication Critical patent/SK284263B6/sk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/282Organic compounds, e.g. fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Mycology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
SK376-99A 1996-09-23 1997-09-18 Perorálny prípravok s oneskoreným pulzným uvoľňovaním a spôsob jeho prípravy SK284263B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96202651 1996-09-23
PCT/EP1997/005234 WO1998013029A1 (en) 1996-09-23 1997-09-18 Oral delayed immediate release formulation and method of preparation therefor

Publications (2)

Publication Number Publication Date
SK37699A3 SK37699A3 (en) 1999-08-06
SK284263B6 true SK284263B6 (sk) 2004-12-01

Family

ID=8224414

Family Applications (1)

Application Number Title Priority Date Filing Date
SK376-99A SK284263B6 (sk) 1996-09-23 1997-09-18 Perorálny prípravok s oneskoreným pulzným uvoľňovaním a spôsob jeho prípravy

Country Status (30)

Country Link
US (1) US6183780B1 (es)
EP (1) EP0939623B1 (es)
JP (1) JP4947824B2 (es)
KR (1) KR100501966B1 (es)
CN (1) CN1161110C (es)
AT (1) ATE213627T1 (es)
AU (1) AU717711B2 (es)
BR (1) BR9711303A (es)
CA (1) CA2263921C (es)
CZ (1) CZ294641B6 (es)
DE (1) DE69710756T2 (es)
DK (1) DK0939623T3 (es)
DZ (1) DZ2314A1 (es)
ES (1) ES2172003T3 (es)
HK (1) HK1019852A1 (es)
HR (1) HRP970493A2 (es)
HU (1) HU226693B1 (es)
ID (1) ID22039A (es)
IL (1) IL128565A (es)
JO (1) JO2066B1 (es)
NO (1) NO325763B1 (es)
NZ (1) NZ334463A (es)
PL (1) PL189016B1 (es)
PT (1) PT939623E (es)
RU (1) RU2193395C2 (es)
SK (1) SK284263B6 (es)
TR (1) TR199900641T2 (es)
UA (1) UA72182C2 (es)
WO (1) WO1998013029A1 (es)
ZA (1) ZA978431B (es)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030109503A1 (en) * 1995-06-06 2003-06-12 Smithkline Beecham P.L.C. Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics
IL139541A0 (en) * 1998-05-20 2004-02-08 Liposome Co Inc Novel particulate formulations
SE9802973D0 (sv) 1998-09-03 1998-09-03 Astra Ab Immediate release tablet
US20010055613A1 (en) * 1998-10-21 2001-12-27 Beth A. Burnside Oral pulsed dose drug delivery system
IL142896A0 (en) * 1998-11-02 2002-04-21 Elan Corp Plc Multiparticulate modified release composition
US6294199B1 (en) * 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
US7250176B1 (en) * 1999-04-13 2007-07-31 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
IE990406A1 (en) * 1999-05-20 2000-12-27 Elan Corp Plc Multiparticulate controlled release selective serotonin reuptake inhibitor formulations.
EP1064937A1 (en) * 1999-06-28 2001-01-03 Sanofi-Synthelabo Timed dual release dosage forms comprising a short acting hypnotic or a salt thereof
EP1074249A1 (en) * 1999-07-27 2001-02-07 Jagotec Ag A pharmaceutical tablet system for releasing at least one active substance during a release period subsequent to a no-release period
US6592869B2 (en) 1999-08-24 2003-07-15 Teva Pharmaceutical Industries, Ltd. Vaccine composition and method of using the same
TR200200477T2 (tr) 1999-08-24 2002-06-21 Teva Pharmaceutical Industries Limited Bir aşı kompozisyonu ve kullanım yöntemi.
US6485746B1 (en) 2000-08-25 2002-11-26 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
ES2199857T3 (es) * 1999-08-26 2004-03-01 Neurocrine Biosciences, Inc. Composiciones sedantes-hipnoticas de liberacion controlada y metodos relacionados con ellas.
DE10012555A1 (de) * 2000-03-15 2001-09-20 Merck Patent Gmbh Glucocorticoide in einer Modified Release-Formulierung
US6720005B1 (en) * 2000-07-07 2004-04-13 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Coated, platform-generating tablet
US6756057B2 (en) 2000-10-12 2004-06-29 Beecham Pharmaceuticals (Pte) Limited Amoxicillin and potassium clavulanate dosage form
WO2002030392A2 (en) 2000-10-12 2002-04-18 Beecham Pharmaceuticals (Pte) Limited Formulation containing amoxicillin
US6913768B2 (en) * 2002-09-24 2005-07-05 Shire Laboratories, Inc. Sustained release delivery of amphetamine salts
US20080220074A1 (en) * 2002-10-04 2008-09-11 Elan Corporation Plc Gamma radiation sterilized nanoparticulate docetaxel compositions and methods of making same
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
AU2004231362B2 (en) 2003-04-24 2009-11-12 Jagotec Ag Delayed release tablet with defined core geometry
ES2335008T3 (es) * 2003-04-24 2010-03-18 Jagotec Ag Comprimido con nucleo coloreado.
AP1899A (en) * 2003-08-08 2008-10-10 Biovail Lab Int Srl Modified-release tablet of bupropion hydrochloride
ES2383525T3 (es) 2003-11-05 2012-06-21 Sarcode Bioscience Inc. Moduladores de la adhesión celular
EP1750862B1 (en) * 2004-06-04 2011-01-05 Teva Pharmaceutical Industries Ltd. Pharmaceutical composition containing irbesartan
DE102004043863A1 (de) 2004-09-10 2006-03-16 Nitec Pharma Ag Tabletten mit orts- und zeitgesteuerter Wirkstofffreisetzung im Gastrointestinum
GB0423964D0 (en) * 2004-10-28 2004-12-01 Jagotec Ag Dosage form
WO2006063078A2 (en) * 2004-12-08 2006-06-15 Elan Corporation, Plc Topiramate pharmaceuticals composition
MX2007012763A (es) * 2005-04-12 2008-01-14 Elan Pharma Int Ltd Composiciones de liberacion controlada que comprenden una cefalosporina para el tratamiento de infeccion bacteriana.
CA2609053C (en) 2005-05-17 2017-04-25 Sarcode Corporation Compositions and methods for treatment of eye disorders
WO2007037790A2 (en) * 2005-06-08 2007-04-05 Elan Corporation, Plc Modified release famciclovir compositions
PL1916995T5 (pl) 2005-07-29 2022-10-31 Stichting Groningen Centre For Drug Research Kontrolowany wartością ph impulsowy układ podawczy, sposoby przygotowania i zastosowanie
US20070036859A1 (en) * 2005-08-11 2007-02-15 Perry Ronald L Sustained release antihistamine and decongestant composition
TWI274889B (en) * 2005-10-06 2007-03-01 Elan Microelectronics Corp Resistive touch screen measurement system
US8187633B2 (en) * 2005-11-03 2012-05-29 Sun Pharma Advanced Research Company Limited Controlled release coated tablets having prolonged gastric retention
ES2400446T5 (es) 2006-08-03 2017-03-13 Horizon Pharma Ag Tratamiento con glucocorticoides de liberación retardada de una enfermedad reumática
US20080081067A1 (en) * 2006-10-03 2008-04-03 Gupta Manishkumar Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof
ES2393885T7 (es) 2007-06-04 2014-01-30 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2009021127A2 (en) * 2007-08-07 2009-02-12 Neurogen Corporation Controlled released compositions
EP3797775A1 (en) 2007-10-19 2021-03-31 Novartis AG Compositions and methods for treatment of diabetic retinopathy
WO2009139817A2 (en) 2008-04-15 2009-11-19 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
ES2522968T3 (es) 2008-06-04 2014-11-19 Synergy Pharmaceuticals Inc. Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
EP2391369A1 (en) * 2009-01-26 2011-12-07 Nitec Pharma AG Delayed-release glucocorticoid treatment of asthma
NZ582836A (en) * 2009-01-30 2011-06-30 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid arthritis by improving signs and symptoms, showing major or complete clinical response and by preventing from joint damage
US8378105B2 (en) 2009-10-21 2013-02-19 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
EP2314296A1 (en) * 2009-10-22 2011-04-27 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Orally Disintegrating Tablets of Betahistine
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2012071220A1 (en) * 2010-11-23 2012-05-31 Transcept Pharmaceuticals, Inc. Compositions and methods for once-daily administration of a trilayer osmotic tablet
RU2453308C1 (ru) * 2010-12-20 2012-06-20 Государственное образовательное учреждение высшего профессионального образования "БАШКИРСКИЙ ГОСУДАРСТВЕННЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ФЕДЕРАЛЬНОГО АГЕНТСТВА ПО ЗДРАВООХРАНЕНИЮ И СОЦИАЛЬНОМУ РАЗВИТИЮ" Драже с оксиметилурацилом и мебеверина гидрохлоридом для лечения функциональных заболеваний желудочно-кишечного тракта
KR102258769B1 (ko) * 2011-10-14 2021-06-01 지엘팜텍주식회사 장용소화효소제 및 그 제조방법
DE102012105528A1 (de) 2012-06-25 2014-01-02 Hennig Arzneimittel Gmbh & Co. Kg Arzneiform zur Freisetzung von Wirkstoffen
MX2015001098A (es) 2012-07-25 2015-09-25 Sarcode Bioscience Inc Inhibidor del antigeno-1 asociado a la funcion del linfocito (lfa-1) y polimorfo del mismo.
AU2014218599C1 (en) 2013-02-25 2018-09-06 Bausch Health Ireland Limited Guanylate cyclase receptor agonists for use in colonic cleansing
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
EP3054969B1 (en) 2013-10-10 2021-03-10 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of opioid induced dysfunctions
CN107708701A (zh) * 2015-06-30 2018-02-16 纽拉德有限公司 新颖呼吸控制调节化合物以及其制备和使用方法
CA3009814A1 (en) 2016-01-11 2017-07-20 Synergy Pharmaceuticals, Inc. Formulations and methods for treating ulcerative colitis
CN108836948B (zh) * 2018-06-11 2024-04-12 宁波西敦医药包衣科技有限公司 一种利用包衣技术实现营养素可控制释放的产品
RU2695135C1 (ru) * 2018-07-11 2019-07-22 Федеральное государственное унитарное предприятие "Научно-исследовательский институт гигиены, профпатологии и экологии человека" Федерального медико-биологического агентства Двухуровневая микрогранулированная форма терапевтического пептида для перорального применения и способ ее получения
CN110403912A (zh) * 2019-09-04 2019-11-05 西安科力康医药科技有限公司 缓控释包衣粉

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH666405A5 (de) * 1985-06-24 1988-07-29 Ciba Geigy Ag Feste, haltbare darreichungsformen mit elastischem filmueberzug.
GB8524001D0 (en) * 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
US5122384A (en) * 1989-05-05 1992-06-16 Kv Pharmaceutical Company Oral once-per-day organic nitrate formulation which does not induce tolerance
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US5032405A (en) * 1989-09-27 1991-07-16 Warner-Lambert Company Oral pharmaceutical composition for acid sensitive proteinaceous agents
FR2655266B1 (fr) * 1989-12-05 1992-04-03 Smith Kline French Lab Compositions pharmaceutiques a base de cimetidine.
US5229131A (en) * 1990-02-05 1993-07-20 University Of Michigan Pulsatile drug delivery system
US5158777A (en) * 1990-02-16 1992-10-27 E. R. Squibb & Sons, Inc. Captopril formulation providing increased duration of activity
GB9104854D0 (en) * 1991-03-07 1991-04-17 Reckitt & Colmann Prod Ltd Sustained release compositions
US5286497A (en) 1991-05-20 1994-02-15 Carderm Capital L.P. Diltiazem formulation
WO1993019741A1 (en) * 1992-03-31 1993-10-14 Benzon Pharma A/S A pharmaceutical formulation
US5500227A (en) * 1993-11-23 1996-03-19 Euro-Celtique, S.A. Immediate release tablet cores of insoluble drugs having sustained-release coating
CN1096862C (zh) * 1994-05-06 2002-12-25 辉瑞大药厂 阿齐霉素的控释剂型

Also Published As

Publication number Publication date
AU717711B2 (en) 2000-03-30
CN1161110C (zh) 2004-08-11
NO991385L (no) 1999-05-25
NO991385D0 (no) 1999-03-22
HU226693B1 (en) 2009-06-29
CZ99599A3 (cs) 1999-06-16
CZ294641B6 (cs) 2005-02-16
HUP9904121A2 (hu) 2000-04-28
TR199900641T2 (xx) 1999-07-21
EP0939623B1 (en) 2002-02-27
AU4557097A (en) 1998-04-17
UA72182C2 (en) 2005-02-15
KR20010029536A (ko) 2001-04-06
CA2263921A1 (en) 1998-04-02
CA2263921C (en) 2006-05-23
HRP970493A2 (en) 1998-08-31
EP0939623A1 (en) 1999-09-08
BR9711303A (pt) 1999-08-17
PT939623E (pt) 2002-08-30
US6183780B1 (en) 2001-02-06
PL189016B1 (pl) 2005-06-30
DE69710756T2 (de) 2002-10-24
SK37699A3 (en) 1999-08-06
IL128565A (en) 2003-02-12
KR100501966B1 (ko) 2005-07-20
WO1998013029A1 (en) 1998-04-02
DE69710756D1 (de) 2002-04-04
CN1231601A (zh) 1999-10-13
ZA978431B (en) 1998-03-26
NZ334463A (en) 2000-12-22
HUP9904121A3 (en) 2004-10-28
DK0939623T3 (da) 2002-06-10
ATE213627T1 (de) 2002-03-15
RU2193395C2 (ru) 2002-11-27
HK1019852A1 (en) 2000-03-03
DZ2314A1 (fr) 2002-12-28
PL332245A1 (en) 1999-08-30
IL128565A0 (en) 2000-01-31
JO2066B1 (en) 2000-05-21
JP4947824B2 (ja) 2012-06-06
ES2172003T3 (es) 2002-09-16
NO325763B1 (no) 2008-07-14
ID22039A (id) 1999-08-26
JP2001500885A (ja) 2001-01-23

Similar Documents

Publication Publication Date Title
SK284263B6 (sk) Perorálny prípravok s oneskoreným pulzným uvoľňovaním a spôsob jeho prípravy
Santus et al. An in vitro-in vivo investigation of oral bioadhesive controlled release furosemide formulations
JP2916978B2 (ja) 放出開始制御型製剤
US4218433A (en) Constant-rate eluting tablet and method of producing same
JP4012689B2 (ja) 新規徐放性経口製剤
CA1148084A (en) Dipyridamol sustained release forms and processes for the preparation thereof
US5133974A (en) Extended release pharmaceutical formulations
AU671830B2 (en) A Pharmaceutical Preparation of Dichloromethylene Bisphosphonic Acid with Enteric Coating for Oral Use
EP0255404B1 (en) Sustained release ibuprofen formulation
IL147212A (en) Process to create coated kernels with camouflaged flavor
GB1567727A (en) Constant rate release tablets
CN104812378B (zh) 固体剂型
IL106477A (en) Morphine salt preparations with controlled release
JP2000515871A (ja) トラマドール複式ユニット製剤
SK89599A3 (en) Rapidly releasing and taste-masking pharmaceutical dosage form
WO2000009133A1 (en) Sustained release oral preparations of fasudil hydrochloride
JPH0733682A (ja) 新規複合体、それを担体として利用する徐放性製剤
DK2679216T3 (en) Pharmaceutical form for modified release of betahistine
US4863741A (en) Tablet composition for drug combinations
NO331480B1 (no) Farmasoytiske sammensetninger med kontrollert frigivelse
RU2411035C2 (ru) Лекарственная форма с модифицированным высвобождением 6-метил-2-этил-3-гидроксипиридина сукцината
CN111346066A (zh) 含吡拉西坦的缓释制剂
EP0196002B1 (en) Tablet composition for drug combinations
Ostwal et al. Development and evaluation for tablet-in capsule of nefedipine and atenolol

Legal Events

Date Code Title Description
PC4A Assignment and transfer of rights

Owner name: ABBOTT PRODUCTS OPERATIONS A.G., ALLSCHWIL, CH

Free format text: FORMER OWNER: ABBOTT HEALTHCARE PRODUCTS B.V., CP WEESP, NL

Effective date: 20120622

Owner name: ABBOTT HEALTHCARE PRODUCTS B.V., CP WEESP, NL

Free format text: FORMER OWNER: DUPHAR INTERNATIONAL RESEARCH B. V., WEESP, NL

Effective date: 20120622

MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20130918