SK284234B6 - Acridine derivatives, method of production thereof and the use of said as agents in pharmaceutical compositions - Google Patents

Acridine derivatives, method of production thereof and the use of said as agents in pharmaceutical compositions Download PDF

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Publication number
SK284234B6
SK284234B6 SK908-99A SK90899A SK284234B6 SK 284234 B6 SK284234 B6 SK 284234B6 SK 90899 A SK90899 A SK 90899A SK 284234 B6 SK284234 B6 SK 284234B6
Authority
SK
Slovakia
Prior art keywords
carbon atoms
hydrochloride
dimethylaminomethyl
methoxyphenyl
hydrogen atom
Prior art date
Application number
SK908-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK90899A3 (en
Inventor
Claudia Katharina Putz
Wolfgang Werner A Strassburger
Osvald Zimmer
Werner Gunter Englberger
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of SK90899A3 publication Critical patent/SK90899A3/sk
Publication of SK284234B6 publication Critical patent/SK284234B6/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/06Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/02Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with only hydrogen, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Press Drives And Press Lines (AREA)
SK908-99A 1998-07-06 1999-07-02 Acridine derivatives, method of production thereof and the use of said as agents in pharmaceutical compositions SK284234B6 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19830105A DE19830105C1 (de) 1998-07-06 1998-07-06 Acridinderivate

Publications (2)

Publication Number Publication Date
SK90899A3 SK90899A3 (en) 2000-03-13
SK284234B6 true SK284234B6 (en) 2004-11-03

Family

ID=7873106

Family Applications (1)

Application Number Title Priority Date Filing Date
SK908-99A SK284234B6 (en) 1998-07-06 1999-07-02 Acridine derivatives, method of production thereof and the use of said as agents in pharmaceutical compositions

Country Status (29)

Country Link
US (2) US6077845A (fr)
EP (2) EP0970949B1 (fr)
JP (1) JP2000026426A (fr)
KR (1) KR100601742B1 (fr)
CN (1) CN1206221C (fr)
AR (1) AR019219A1 (fr)
AT (1) ATE247643T1 (fr)
AU (1) AU749935B2 (fr)
BR (1) BR9903115A (fr)
CA (1) CA2276764C (fr)
CO (1) CO5080790A1 (fr)
CZ (1) CZ296559B6 (fr)
DE (2) DE19830105C1 (fr)
DK (1) DK0970949T3 (fr)
ES (1) ES2205642T3 (fr)
HK (1) HK1024699A1 (fr)
HU (1) HU226039B1 (fr)
IL (1) IL130801A (fr)
MY (1) MY124404A (fr)
NO (1) NO312958B1 (fr)
NZ (1) NZ336122A (fr)
PE (1) PE20000733A1 (fr)
PL (1) PL193386B1 (fr)
PT (1) PT970949E (fr)
RU (1) RU2225399C2 (fr)
SI (1) SI0970949T1 (fr)
SK (1) SK284234B6 (fr)
UY (1) UY25592A1 (fr)
ZA (1) ZA994369B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10000311A1 (de) * 2000-01-05 2001-07-12 Gruenenthal Gmbh Aminomethyl-Phonyl-Cyclohexanonderivate
KR100381716B1 (ko) * 2000-10-09 2003-04-26 한국화학연구원 항암활성을 가지는 아크리딘 유도체
HUE026184T2 (en) * 2008-03-27 2016-05-30 Gruenenthal Gmbh (Hetero-) aryl-cyclohexane derivatives
CN105315205B (zh) * 2015-01-19 2018-03-23 威海惠安康生物科技有限公司 一种以邻硝基苯甲醛和环己醇为原料制备吖啶的方法
RU2616247C1 (ru) * 2016-03-28 2017-04-13 Федеральное государственное бюджетное образовательное учреждение высшего образования "Северо-Осетинский государственный университет имени Коста Левановича Хетагурова" (СОГУ) Твердая лекарственная форма, обладающая холинопозитивным действием, на основе 9-бутиламино-3,3-диметил-1,2,4-тригидроакридина

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3652589A (en) * 1967-07-27 1972-03-28 Gruenenthal Chemie 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
US4851536A (en) * 1987-05-07 1989-07-25 American Home Products Corporation Cyclohexylquinolines as inhibitors of interleukin 1
DE19525137C2 (de) * 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe
DE19547766A1 (de) * 1995-12-20 1997-06-26 Gruenenthal Gmbh 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol-verbindungen als pharmazeutische Wirkstoffe
DE19609847A1 (de) * 1996-03-13 1997-09-18 Gruenenthal Gmbh Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe
DE19805370A1 (de) * 1997-03-14 1998-09-17 Gruenenthal Gmbh Substituierte Aminoverbindungen und ihre Verwendung als analgetisch wirksame Substanzen
DE19755480A1 (de) * 1997-12-13 1999-06-24 Gruenenthal Gmbh Substituierte heterocyclische Benzocycloalkene und ihre Verwendung als analgetisch wirksame Substanzen

Also Published As

Publication number Publication date
AU749935B2 (en) 2002-07-04
EP0970949B1 (fr) 2003-08-20
CZ296559B6 (cs) 2006-04-12
CZ240799A3 (cs) 2000-01-12
HK1024699A1 (en) 2000-10-20
BR9903115A (pt) 2000-06-20
CO5080790A1 (es) 2001-09-25
DE59906645D1 (de) 2003-09-25
IL130801A0 (en) 2001-01-28
EP1369417A1 (fr) 2003-12-10
KR100601742B1 (ko) 2006-07-19
SK90899A3 (en) 2000-03-13
DK0970949T3 (da) 2003-11-24
EP0970949A1 (fr) 2000-01-12
NZ336122A (en) 2001-02-23
RU2225399C2 (ru) 2004-03-10
CA2276764A1 (fr) 2000-01-06
CN1206221C (zh) 2005-06-15
KR20000011483A (ko) 2000-02-25
CA2276764C (fr) 2009-08-18
AR019219A1 (es) 2001-12-26
NO993320D0 (no) 1999-07-05
UY25592A1 (es) 2001-05-31
JP2000026426A (ja) 2000-01-25
SI0970949T1 (en) 2003-12-31
DE19830105C1 (de) 2000-02-17
HU9902270D0 (en) 1999-09-28
HU226039B1 (en) 2008-03-28
NO993320L (no) 2000-01-07
ES2205642T3 (es) 2004-05-01
AU3798399A (en) 2000-01-20
PE20000733A1 (es) 2000-08-12
PT970949E (pt) 2003-12-31
NO312958B1 (no) 2002-07-22
PL193386B1 (pl) 2007-02-28
ATE247643T1 (de) 2003-09-15
IL130801A (en) 2006-06-11
US6077845A (en) 2000-06-20
CN1240788A (zh) 2000-01-12
MY124404A (en) 2006-06-30
HUP9902270A1 (hu) 2000-06-28
US6274768B1 (en) 2001-08-14
ZA994369B (en) 2000-01-11

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20100702