SK282039B6 - Oftalmický prípravok na liečenie očnej hypertenzie obsahujúci kombináciu inhibítora karboanhydrázy a beta-adrenergného antagonistu - Google Patents

Oftalmický prípravok na liečenie očnej hypertenzie obsahujúci kombináciu inhibítora karboanhydrázy a beta-adrenergného antagonistu Download PDF

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Publication number
SK282039B6
SK282039B6 SK1103-93A SK110393A SK282039B6 SK 282039 B6 SK282039 B6 SK 282039B6 SK 110393 A SK110393 A SK 110393A SK 282039 B6 SK282039 B6 SK 282039B6
Authority
SK
Slovakia
Prior art keywords
carbonic anhydrase
water
solution
sodium
formulation
Prior art date
Application number
SK1103-93A
Other languages
English (en)
Slovak (sk)
Other versions
SK110393A3 (en
Inventor
John J. Baldwin
Original Assignee
Merck & Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27103852&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK282039(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co., Inc. filed Critical Merck & Co., Inc.
Publication of SK110393A3 publication Critical patent/SK110393A3/sk
Publication of SK282039B6 publication Critical patent/SK282039B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SK1103-93A 1991-04-17 1992-04-09 Oftalmický prípravok na liečenie očnej hypertenzie obsahujúci kombináciu inhibítora karboanhydrázy a beta-adrenergného antagonistu SK282039B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68671891A 1991-04-17 1991-04-17
US83491392A 1992-02-13 1992-02-13
PCT/US1992/002903 WO1992018124A1 (en) 1991-04-17 1992-04-09 OPHTHALMIC COMPOSITIONS COMPRISING COMBINATIONS OF A CARBONIC ANHYDRASE INHIBITOR AND A β-ADRENERGIC ANTAGONIST

Publications (2)

Publication Number Publication Date
SK110393A3 SK110393A3 (en) 1994-02-02
SK282039B6 true SK282039B6 (sk) 2001-10-08

Family

ID=27103852

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1103-93A SK282039B6 (sk) 1991-04-17 1992-04-09 Oftalmický prípravok na liečenie očnej hypertenzie obsahujúci kombináciu inhibítora karboanhydrázy a beta-adrenergného antagonistu

Country Status (25)

Country Link
EP (1) EP0509752B1 (nl)
JP (1) JP2527513B2 (nl)
KR (1) KR920019348A (nl)
CN (1) CN1073421C (nl)
AT (1) ATE182787T1 (nl)
AU (1) AU648659C (nl)
CA (1) CA2065965C (nl)
CH (1) CH0509752H1 (nl)
CY (1) CY2146B1 (nl)
CZ (1) CZ285129B6 (nl)
DE (3) DE69229688C5 (nl)
DK (1) DK0509752T3 (nl)
ES (1) ES2133304T3 (nl)
GR (1) GR3031467T3 (nl)
HK (1) HK1009251A1 (nl)
IE (1) IE921240A1 (nl)
IL (1) IL101537A (nl)
LU (1) LU90506I2 (nl)
MX (1) MX9201785A (nl)
NL (1) NL990041I2 (nl)
NO (1) NO306196B1 (nl)
RO (1) RO113612B1 (nl)
SK (1) SK282039B6 (nl)
WO (1) WO1992018124A1 (nl)
YU (1) YU39392A (nl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5932572A (en) * 1992-02-21 1999-08-03 Alcon Laboratories, Inc. Topical anti-glaucoma compositions
DE69320329T2 (de) * 1992-02-21 1998-12-24 Alcon Laboratories, Inc., Fort Worth, Tex. Topische Antiglaukoma Zusammensetzungen, enthaltend Karbonhydrasehemmer und Beta-Blocker
US6071904A (en) * 1996-12-11 2000-06-06 Alcon Laboratories, Inc. Process for manufacturing ophthalmic suspensions
FI981473A (fi) * 1998-06-25 1999-12-26 Orion Yhtymae Oyj Menetelmä pulmonaalihypertension hoitamiseksi
TWI298257B (en) 2001-05-31 2008-07-01 Allergan Inc Hypotensive lipid and timolol compositions and methods of using same
CN100345594C (zh) * 2004-01-19 2007-10-31 无锡杰西医药科技有限公司 乙酰唑胺滴眼液
US8211450B2 (en) * 2010-05-05 2012-07-03 Senju Usa, Inc. Ophthalmic composition
KR101820184B1 (ko) 2010-07-29 2018-01-18 알러간, 인코포레이티드 방부제가 없는 비마토프로스트 및 티몰롤 용액
US9061034B2 (en) 2010-07-29 2015-06-23 Allergan, Inc. Preservative free bimatoprost and timolol solutions
JP5893204B1 (ja) * 2015-02-23 2016-03-23 参天製薬株式会社 防腐効果のある医薬の組合せ
JP6132968B1 (ja) * 2016-01-29 2017-05-24 参天製薬株式会社 ドルゾラミド、高分子およびホウ酸を含有する医薬組成物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4863922A (en) * 1984-12-12 1989-09-05 Merck & Co., Inc. Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use

Also Published As

Publication number Publication date
DE10075002I2 (de) 2004-07-01
NL990041I2 (nl) 2000-04-03
LU90506I2 (fr) 2000-03-28
JPH05117167A (ja) 1993-05-14
NO933714L (no) 1993-10-15
KR920019348A (ko) 1992-11-19
DE10075002I1 (de) 2000-03-30
NL990041I1 (nl) 2000-02-01
NO933714D0 (no) 1993-10-15
HK1009251A1 (en) 1999-05-28
SK110393A3 (en) 1994-02-02
NO306196B1 (no) 1999-10-04
MX9201785A (es) 1992-10-01
YU39392A (sh) 1995-12-04
EP0509752A2 (en) 1992-10-21
WO1992018124A1 (en) 1992-10-29
EP0509752B1 (en) 1999-08-04
AU648659C (en) 2008-02-14
ATE182787T1 (de) 1999-08-15
IL101537A0 (en) 1992-12-30
ES2133304T3 (es) 1999-09-16
DE69229688T4 (de) 2010-08-19
CY2146B1 (en) 2002-06-21
IL101537A (en) 1997-11-20
CN1073421C (zh) 2001-10-24
AU648659B2 (en) 1994-04-28
AU1497992A (en) 1992-10-22
GR3031467T3 (en) 2000-01-31
CA2065965C (en) 1998-06-16
DE69229688C5 (de) 2010-10-21
RO113612B1 (ro) 1998-09-30
DE69229688T2 (de) 2000-02-24
CZ209893A3 (en) 1994-06-15
DE69229688D1 (de) 1999-09-09
JP2527513B2 (ja) 1996-08-28
CH0509752H1 (nl) 2012-11-30
CA2065965A1 (en) 1992-10-18
DK0509752T3 (da) 1999-12-06
IE921240A1 (en) 1992-10-21
CN1066781A (zh) 1992-12-09
EP0509752A3 (en) 1993-03-03
CZ285129B6 (cs) 1999-05-12

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Legal Events

Date Code Title Description
TC4A Change of owner's name

Owner name: MERCK SHARP & DOHME CORP., RAHWAY, NJ, US

Effective date: 20100510

MG4A Partial revocation of patent

Effective date: 20111212

MK4A Patent expired

Expiry date: 20120409

SPCT Transfer of rights of an spc

Owner name: SCHERING CORPORATION; US

Free format text: PRODUCT NAME: MONOHYDROCHLORID (4S,6S)-4-(ETYLAMINO)-5,6-DIHYDRO-6-METYL-4H-TIENO¬2,3- -B|TIOPYRAN-2-SULFONAMID-7,7-DIOXIDU A MALEAT S-(-)-3-(3-TERC-BUTYLAMINO-2-HYDROXYPROPOXY)-4-MORFOLINO- -1,2,5-TIADIAZOL (HYDROCHLORID DORZOLAMIDU A MALEAT TIMOLOLU); REGISTRATION NO/DATE: 64/0218/00-S 20000710

Spc suppl protection certif: DO 8; 5-2002

Filing date: 20021025

Extension date: 20150710

Effective date: 20130128

MC4A Annulment of patent

Effective date: 20140609