GR3031467T3 - Ophthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a beta-adrenergic antagonist - Google Patents

Ophthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a beta-adrenergic antagonist

Info

Publication number
GR3031467T3
GR3031467T3 GR990402558T GR990402558T GR3031467T3 GR 3031467 T3 GR3031467 T3 GR 3031467T3 GR 990402558 T GR990402558 T GR 990402558T GR 990402558 T GR990402558 T GR 990402558T GR 3031467 T3 GR3031467 T3 GR 3031467T3
Authority
GR
Greece
Prior art keywords
beta
combinations
carbonic anhydrase
anhydrase inhibitor
adrenergic antagonist
Prior art date
Application number
GR990402558T
Other languages
Greek (el)
Inventor
John J Baldwin
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27103852&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR3031467(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of GR3031467T3 publication Critical patent/GR3031467T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

Combinations of a beta -adrenergic antagonist and a topical carbonic anhydrase inhibitor are particularly useful in the treatment of ocular hypertension, especially in patients insufficiently responsive to treatment with beta -adrenergic antagonists. <IMAGE>
GR990402558T 1991-04-17 1999-10-08 Ophthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a beta-adrenergic antagonist GR3031467T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68671891A 1991-04-17 1991-04-17
US83491392A 1992-02-13 1992-02-13

Publications (1)

Publication Number Publication Date
GR3031467T3 true GR3031467T3 (en) 2000-01-31

Family

ID=27103852

Family Applications (1)

Application Number Title Priority Date Filing Date
GR990402558T GR3031467T3 (en) 1991-04-17 1999-10-08 Ophthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a beta-adrenergic antagonist

Country Status (25)

Country Link
EP (1) EP0509752B1 (en)
JP (1) JP2527513B2 (en)
KR (1) KR920019348A (en)
CN (1) CN1073421C (en)
AT (1) ATE182787T1 (en)
AU (1) AU648659C (en)
CA (1) CA2065965C (en)
CH (1) CH0509752H1 (en)
CY (1) CY2146B1 (en)
CZ (1) CZ285129B6 (en)
DE (3) DE10075002I2 (en)
DK (1) DK0509752T3 (en)
ES (1) ES2133304T3 (en)
GR (1) GR3031467T3 (en)
HK (1) HK1009251A1 (en)
IE (1) IE921240A1 (en)
IL (1) IL101537A (en)
LU (1) LU90506I2 (en)
MX (1) MX9201785A (en)
NL (1) NL990041I2 (en)
NO (1) NO306196B1 (en)
RO (1) RO113612B1 (en)
SK (1) SK282039B6 (en)
WO (1) WO1992018124A1 (en)
YU (1) YU39392A (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU677577B2 (en) * 1992-02-21 1997-05-01 Alcon Laboratories, Inc. Topical antiglaucoma compositions comprising carbonic anhydrase inhibitors and beta-blockers
US5932572A (en) * 1992-02-21 1999-08-03 Alcon Laboratories, Inc. Topical anti-glaucoma compositions
US6071904A (en) * 1996-12-11 2000-06-06 Alcon Laboratories, Inc. Process for manufacturing ophthalmic suspensions
FI981473A (en) * 1998-06-25 1999-12-26 Orion Yhtymae Oyj A method of treating pulmonary hypertension
TWI298257B (en) 2001-05-31 2008-07-01 Allergan Inc Hypotensive lipid and timolol compositions and methods of using same
CN100345594C (en) * 2004-01-19 2007-10-31 无锡杰西医药科技有限公司 Acetazolamide eye droplet and its application method in treating glaucoma
US8211450B2 (en) * 2010-05-05 2012-07-03 Senju Usa, Inc. Ophthalmic composition
CA2807081C (en) 2010-07-29 2018-09-18 Allergan, Inc. Preservative free bimatoprost and timolol solutions
US9061034B2 (en) 2010-07-29 2015-06-23 Allergan, Inc. Preservative free bimatoprost and timolol solutions
JP5893204B1 (en) * 2015-02-23 2016-03-23 参天製薬株式会社 Combination of antiseptic drugs
TW201726127A (en) * 2016-01-29 2017-08-01 參天製藥股份有限公司 Pharmaceutical composition containing dorzolamide, polymer and boric acid by adding boric acid or a salt thereof to a pharmaceutical composition of pH 6.0 or lower that contains dorzolamide or a salt thereof and a polymer to inhibit decrease in viscosity over a period of time

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4863922A (en) * 1984-12-12 1989-09-05 Merck & Co., Inc. Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use

Also Published As

Publication number Publication date
DK0509752T3 (en) 1999-12-06
JPH05117167A (en) 1993-05-14
EP0509752B1 (en) 1999-08-04
CH0509752H1 (en) 2012-11-30
CZ209893A3 (en) 1994-06-15
LU90506I2 (en) 2000-03-28
AU648659C (en) 2008-02-14
WO1992018124A1 (en) 1992-10-29
CN1073421C (en) 2001-10-24
HK1009251A1 (en) 1999-05-28
AU1497992A (en) 1992-10-22
RO113612B1 (en) 1998-09-30
JP2527513B2 (en) 1996-08-28
ATE182787T1 (en) 1999-08-15
EP0509752A2 (en) 1992-10-21
MX9201785A (en) 1992-10-01
CA2065965A1 (en) 1992-10-18
AU648659B2 (en) 1994-04-28
ES2133304T3 (en) 1999-09-16
NO306196B1 (en) 1999-10-04
SK110393A3 (en) 1994-02-02
CN1066781A (en) 1992-12-09
DE69229688D1 (en) 1999-09-09
IL101537A0 (en) 1992-12-30
NO933714D0 (en) 1993-10-15
SK282039B6 (en) 2001-10-08
DE69229688T4 (en) 2010-08-19
CY2146B1 (en) 2002-06-21
YU39392A (en) 1995-12-04
IE921240A1 (en) 1992-10-21
DE69229688T2 (en) 2000-02-24
EP0509752A3 (en) 1993-03-03
DE10075002I1 (en) 2000-03-30
DE69229688C5 (en) 2010-10-21
DE10075002I2 (en) 2004-07-01
CZ285129B6 (en) 1999-05-12
NL990041I1 (en) 2000-02-01
NL990041I2 (en) 2000-04-03
KR920019348A (en) 1992-11-19
CA2065965C (en) 1998-06-16
IL101537A (en) 1997-11-20
NO933714L (en) 1993-10-15

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