SK281876B6 - Substituované benzénsulfonylmočoviny a benzénsulfonyltiomočoviny, spôsob ich výroby, ich použitie na výrobu farmaceutických prostriedkov a liečivá, ktoré ich obsahujú - Google Patents

Substituované benzénsulfonylmočoviny a benzénsulfonyltiomočoviny, spôsob ich výroby, ich použitie na výrobu farmaceutických prostriedkov a liečivá, ktoré ich obsahujú Download PDF

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Publication number
SK281876B6
SK281876B6 SK222-96A SK22296A SK281876B6 SK 281876 B6 SK281876 B6 SK 281876B6 SK 22296 A SK22296 A SK 22296A SK 281876 B6 SK281876 B6 SK 281876B6
Authority
SK
Slovakia
Prior art keywords
carbon atoms
atom
group containing
group
formula
Prior art date
Application number
SK222-96A
Other languages
English (en)
Slovak (sk)
Other versions
SK22296A3 (en
Inventor
Heinrich Englert
Uwe Gerlach
Dieter Mania
Heinz G�Gelein
Joachim Kaiser
Original Assignee
Hoechst Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Aktiengesellschaft filed Critical Hoechst Aktiengesellschaft
Publication of SK22296A3 publication Critical patent/SK22296A3/sk
Publication of SK281876B6 publication Critical patent/SK281876B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52—Y being a hetero atom
    • C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
    • C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/58—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/40—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
    • C07C335/42—Sulfonylthioureas; Sulfonylisothioureas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
SK222-96A 1995-02-21 1996-02-19 Substituované benzénsulfonylmočoviny a benzénsulfonyltiomočoviny, spôsob ich výroby, ich použitie na výrobu farmaceutických prostriedkov a liečivá, ktoré ich obsahujú SK281876B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19505910A DE19505910A1 (de) 1995-02-21 1995-02-21 Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung zur Herstellung pharmazeutischer Präparate und sie enthaltende Medikamente

Publications (2)

Publication Number Publication Date
SK22296A3 SK22296A3 (en) 1996-10-02
SK281876B6 true SK281876B6 (sk) 2001-08-06

Family

ID=7754593

Family Applications (1)

Application Number Title Priority Date Filing Date
SK222-96A SK281876B6 (sk) 1995-02-21 1996-02-19 Substituované benzénsulfonylmočoviny a benzénsulfonyltiomočoviny, spôsob ich výroby, ich použitie na výrobu farmaceutických prostriedkov a liečivá, ktoré ich obsahujú

Country Status (30)

Country Link
US (1) US5633239A (el)
EP (1) EP0728741B1 (el)
JP (1) JP3905570B2 (el)
KR (1) KR100446566B1 (el)
CN (1) CN1060767C (el)
AR (1) AR001352A1 (el)
AT (1) ATE196467T1 (el)
AU (1) AU701278B2 (el)
BR (1) BR9600773A (el)
CA (1) CA2169695C (el)
CZ (1) CZ291219B6 (el)
DE (2) DE19505910A1 (el)
DK (1) DK0728741T3 (el)
ES (1) ES2151614T3 (el)
FI (1) FI120392B (el)
GR (1) GR3034646T3 (el)
HR (1) HRP960081B1 (el)
HU (1) HU227308B1 (el)
IL (1) IL117179A (el)
MY (1) MY113432A (el)
NO (1) NO305792B1 (el)
NZ (1) NZ286013A (el)
PL (1) PL181628B1 (el)
PT (1) PT728741E (el)
RU (1) RU2159763C2 (el)
SI (1) SI9600053B (el)
SK (1) SK281876B6 (el)
TR (1) TR199600129A2 (el)
TW (1) TW357140B (el)
ZA (1) ZA961314B (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19832009A1 (de) 1998-07-16 2000-01-20 Hoechst Marion Roussel De Gmbh 2,5-Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharamazeutische Präparate
US6436864B1 (en) 1999-10-06 2002-08-20 Sri International Unsaturated nitrogenous compounds as electron donors for use with ziegler-natta catalysts
DE10129704A1 (de) * 2001-06-22 2003-01-02 Aventis Pharma Gmbh Verwendung von Benzolsulfonyl(thio)harnstoffen in der Behandlung des septischen Schocks
CN101160285A (zh) * 2005-03-17 2008-04-09 辉瑞大药厂 适用于治疗疼痛的n-(n-磺酰氨基甲基)环丙烷甲酰胺衍生物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL141381B (nl) * 1963-09-25 1974-03-15 Hoechst Ag Werkwijze voor het bereiden van geneesmiddelen met bloedsuikerspiegel verlagende werkzaamheid.
DE1198354B (de) * 1963-09-25 1965-08-12 Hoechst Ag Verfahren zur Herstellung von Benzol-sulfonylharnstoffen
BE754454A (fr) * 1969-08-06 1971-02-05 Bayer Ag Nouveaux composes hypoglycemiques du type d'arylsulfonylurees et d'arylsulfonylsemicarbazides contenant des groupes carbonamide
ES2098069T3 (es) * 1993-02-23 1997-04-16 Hoechst Ag Bencenosulfonil-ureas y -tioureas sustituidas, procedimiento para su preparacion y su utilizacion como agentes farmaceuticos.
DE4341655A1 (de) * 1993-12-07 1995-06-08 Hoechst Ag Aminosubstituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung als Pharmazeutika

Also Published As

Publication number Publication date
CN1134932A (zh) 1996-11-06
HUT73974A (en) 1996-10-28
ATE196467T1 (de) 2000-10-15
JPH08245555A (ja) 1996-09-24
TW357140B (en) 1999-05-01
PT728741E (pt) 2001-03-30
EP0728741A1 (de) 1996-08-28
NO960664D0 (no) 1996-02-20
GR3034646T3 (en) 2001-01-31
FI960740A0 (fi) 1996-02-19
NZ286013A (en) 1996-10-28
NO960664L (no) 1996-08-22
SI9600053B (en) 2001-12-31
FI120392B (fi) 2009-10-15
MY113432A (en) 2002-02-28
HRP960081B1 (en) 2001-08-31
AU4560096A (en) 1996-08-29
IL117179A (en) 2000-02-17
BR9600773A (pt) 1997-12-23
PL312529A1 (en) 1996-09-02
HRP960081A2 (en) 1997-10-31
AU701278B2 (en) 1999-01-21
CA2169695A1 (en) 1996-08-22
IL117179A0 (en) 1996-06-18
ZA961314B (en) 1996-08-27
US5633239A (en) 1997-05-27
CZ48696A3 (en) 1996-09-11
CZ291219B6 (cs) 2003-01-15
DE59605898D1 (de) 2000-10-26
AR001352A1 (es) 1997-10-22
KR100446566B1 (ko) 2004-12-03
CA2169695C (en) 2008-05-20
HU9503931D0 (en) 1996-03-28
EP0728741B1 (de) 2000-09-20
ES2151614T3 (es) 2001-01-01
SI9600053A (en) 1996-12-31
KR960031429A (ko) 1996-09-17
FI960740A (fi) 1996-08-22
DE19505910A1 (de) 1996-08-22
TR199600129A2 (tr) 1996-10-21
PL181628B1 (pl) 2001-08-31
SK22296A3 (en) 1996-10-02
DK0728741T3 (da) 2000-12-18
HU227308B1 (en) 2011-03-28
RU2159763C2 (ru) 2000-11-27
CN1060767C (zh) 2001-01-17
JP3905570B2 (ja) 2007-04-18
NO305792B1 (no) 1999-07-26

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Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20120219