SK281363B6 - Derivát alkyl-5-metylsulfonylbenzoguanidínu, spôsob jeho prípravy a farmaceutický prostriedok, ktorý ho obsahuje - Google Patents

Derivát alkyl-5-metylsulfonylbenzoguanidínu, spôsob jeho prípravy a farmaceutický prostriedok, ktorý ho obsahuje Download PDF

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Publication number
SK281363B6
SK281363B6 SK1288-95A SK128895A SK281363B6 SK 281363 B6 SK281363 B6 SK 281363B6 SK 128895 A SK128895 A SK 128895A SK 281363 B6 SK281363 B6 SK 281363B6
Authority
SK
Slovakia
Prior art keywords
methyl
diaminomethylene
formula
ethyl
alkyl
Prior art date
Application number
SK1288-95A
Other languages
English (en)
Slovak (sk)
Other versions
SK128895A3 (en
Inventor
Rolf Gericke
Dieter Dorsch
Manfred Baumgarth
Klaus-Otto Minck
Norbert Beier
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SK128895A3 publication Critical patent/SK128895A3/sk
Publication of SK281363B6 publication Critical patent/SK281363B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/44Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C317/50Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/44Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Phenolic Resins Or Amino Resins (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
SK1288-95A 1994-10-22 1995-10-18 Derivát alkyl-5-metylsulfonylbenzoguanidínu, spôsob jeho prípravy a farmaceutický prostriedok, ktorý ho obsahuje SK281363B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4437874A DE4437874A1 (de) 1994-10-22 1994-10-22 Alkyl-5-methylsulfonyl-benzoylguanidin-Derivate

Publications (2)

Publication Number Publication Date
SK128895A3 SK128895A3 (en) 1996-05-08
SK281363B6 true SK281363B6 (sk) 2001-02-12

Family

ID=6531500

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1288-95A SK281363B6 (sk) 1994-10-22 1995-10-18 Derivát alkyl-5-metylsulfonylbenzoguanidínu, spôsob jeho prípravy a farmaceutický prostriedok, ktorý ho obsahuje

Country Status (26)

Country Link
US (1) US5700839A (ja)
EP (1) EP0708088B1 (ja)
JP (1) JPH08283232A (ja)
KR (1) KR960014100A (ja)
CN (1) CN1057759C (ja)
AT (1) ATE178052T1 (ja)
AU (1) AU698225B2 (ja)
BR (1) BR9504489A (ja)
CA (1) CA2161072A1 (ja)
CO (1) CO4650180A1 (ja)
CZ (1) CZ290615B6 (ja)
DE (2) DE4437874A1 (ja)
DK (1) DK0708088T3 (ja)
ES (1) ES2130491T3 (ja)
FI (1) FI955026A (ja)
GR (1) GR3030513T3 (ja)
HU (1) HU224011B1 (ja)
MX (1) MX9504454A (ja)
NO (1) NO305243B1 (ja)
PL (1) PL180174B1 (ja)
RU (1) RU2158255C2 (ja)
SK (1) SK281363B6 (ja)
TR (1) TR199501278A2 (ja)
TW (1) TW434211B (ja)
UA (1) UA39118C2 (ja)
ZA (1) ZA958909B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4328352A1 (de) 1993-08-24 1995-03-02 Hoechst Ag Substituierte N,N'-Di-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
EP0825187A1 (en) * 1996-08-22 1998-02-25 Takeda Chemical Industries, Ltd. Condensed pyridazinyl guanidines, their production and use
WO2000030624A2 (en) * 1998-11-26 2000-06-02 Merck Patent Gmbh Use of benzoylguanidines for the treatment of non-insulin-dependent diabetes mellitus
US6706732B1 (en) 1999-06-03 2004-03-16 Takeda Chemical Industries, Ltd. Nasal preparation of guanidinoimino quinoline derivatives
DE10023405A1 (de) * 2000-05-12 2001-11-15 Merck Patent Gmbh Verfahren zur Herstellung von Sulfonyl-benzoylguanidinum-Salzen
TW200614995A (en) * 2004-11-10 2006-05-16 Nicholas Piramal India Ltd Tricyclic guanidine derivatives as sodium-proton exchange inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3929582A1 (de) * 1989-09-06 1991-03-07 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament
ATE158278T1 (de) * 1992-02-15 1997-10-15 Hoechst Ag Ortho-substituierte benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament oder diagnostikum sowie sie enthaltendes medikament
EP0589336B1 (de) * 1992-09-22 1997-01-08 Hoechst Aktiengesellschaft Benzoylguanidine, Verfahren zu ihrer Herstellung, sowie ihre Verwendung als Antiarrhythmika
TW250479B (ja) * 1992-12-15 1995-07-01 Hoechst Ag

Also Published As

Publication number Publication date
GR3030513T3 (en) 1999-10-29
FI955026A (fi) 1996-04-23
EP0708088B1 (de) 1999-03-24
TW434211B (en) 2001-05-16
HUT76480A (en) 1997-09-29
ZA958909B (en) 1996-05-29
RU2158255C2 (ru) 2000-10-27
CN1130178A (zh) 1996-09-04
HU9503025D0 (en) 1995-12-28
PL311051A1 (en) 1996-04-29
FI955026A0 (fi) 1995-10-20
NO954198L (no) 1996-04-23
UA39118C2 (uk) 2001-06-15
CZ274495A3 (en) 1996-05-15
DE59505429D1 (de) 1999-04-29
ATE178052T1 (de) 1999-04-15
DK0708088T3 (da) 1999-10-11
MX9504454A (es) 1997-01-31
EP0708088A1 (de) 1996-04-24
US5700839A (en) 1997-12-23
AU698225B2 (en) 1998-10-29
NO305243B1 (no) 1999-04-26
ES2130491T3 (es) 1999-07-01
HU224011B1 (hu) 2005-04-28
TR199501278A2 (tr) 1996-06-21
JPH08283232A (ja) 1996-10-29
NO954198D0 (no) 1995-10-20
CZ290615B6 (cs) 2002-09-11
CO4650180A1 (es) 1998-09-03
DE4437874A1 (de) 1996-04-25
PL180174B1 (pl) 2000-12-29
KR960014100A (ko) 1996-05-22
AU3424295A (en) 1996-05-02
SK128895A3 (en) 1996-05-08
BR9504489A (pt) 1997-05-20
CA2161072A1 (en) 1996-04-23
CN1057759C (zh) 2000-10-25

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