SK281025B6 - (1-fenyl-1-heterocyklyl)alkánové deriváty, spôsoby ich prípravy, medziprodukty na ich prípravu, farmaceutické prostriedky s ich obsahom a ich použitie - Google Patents

(1-fenyl-1-heterocyklyl)alkánové deriváty, spôsoby ich prípravy, medziprodukty na ich prípravu, farmaceutické prostriedky s ich obsahom a ich použitie Download PDF

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Publication number
SK281025B6
SK281025B6 SK1599-95A SK159995A SK281025B6 SK 281025 B6 SK281025 B6 SK 281025B6 SK 159995 A SK159995 A SK 159995A SK 281025 B6 SK281025 B6 SK 281025B6
Authority
SK
Slovakia
Prior art keywords
group
alkyl
formula
compound
aryl
Prior art date
Application number
SK1599-95A
Other languages
English (en)
Slovak (sk)
Other versions
SK159995A3 (en
Inventor
Bernard Robin Boar
Alan John Cross
Duncan Alastair Gray
Alfred Richard Green
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of SK159995A3 publication Critical patent/SK159995A3/sk
Publication of SK281025B6 publication Critical patent/SK281025B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SK1599-95A 1993-07-06 1994-07-05 (1-fenyl-1-heterocyklyl)alkánové deriváty, spôsoby ich prípravy, medziprodukty na ich prípravu, farmaceutické prostriedky s ich obsahom a ich použitie SK281025B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE19939302333A SE9302333D0 (sv) 1993-07-06 1993-07-06 New compounds
PCT/SE1994/000664 WO1995001967A1 (en) 1993-07-06 1994-07-05 Novel (1-phenyl-1-heterocyclyl)alkane derivatives and their use as neuroprotective agents

Publications (2)

Publication Number Publication Date
SK159995A3 SK159995A3 (en) 1996-06-05
SK281025B6 true SK281025B6 (sk) 2000-11-07

Family

ID=20390540

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1599-95A SK281025B6 (sk) 1993-07-06 1994-07-05 (1-fenyl-1-heterocyklyl)alkánové deriváty, spôsoby ich prípravy, medziprodukty na ich prípravu, farmaceutické prostriedky s ich obsahom a ich použitie

Country Status (18)

Country Link
US (1) US5747515A (no)
EP (1) EP0707573A1 (no)
JP (1) JPH08512313A (no)
CN (1) CN1044705C (no)
AU (1) AU691191B2 (no)
BR (1) BR9406924A (no)
CA (1) CA2164876A1 (no)
CZ (1) CZ4196A3 (no)
FI (1) FI960077A (no)
HU (1) HUT74673A (no)
IS (1) IS1742B (no)
NO (1) NO305862B1 (no)
NZ (1) NZ268690A (no)
PL (1) PL179021B1 (no)
RU (1) RU2137763C1 (no)
SE (1) SE9302333D0 (no)
SK (1) SK281025B6 (no)
WO (1) WO1995001967A1 (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2774596B1 (fr) * 1998-02-11 2000-03-17 Rhone Poulenc Rorer Sa Utilisation de composes selenies dans la prevention et le traitement de la maladie d'alzheimer
CA2328973A1 (en) 1998-04-23 1999-10-28 Akio Ojida Naphthalene derivatives, their production and use
US6503935B1 (en) 1998-08-07 2003-01-07 Abbott Laboratories Imidazoles and related compounds as α1A agonists
US6156775A (en) * 1999-03-01 2000-12-05 Novartis Ag Use of fluorinated triazoles in treating affective and attention disorders
EP1193258A4 (en) * 1999-06-22 2002-11-13 Takeda Chemical Industries Ltd PROCESS FOR THE PREPARATION OF IMIDAZOLE DERIVATIVES
SE9904177D0 (sv) * 1999-11-18 1999-11-18 Astra Ab Novel compounds
WO2008064317A1 (en) * 2006-11-22 2008-05-29 University Of Medicine And Dentistry Of New Jersey Lipophilic opioid receptor active compounds
JP2014525442A (ja) * 2011-08-30 2014-09-29 ヴィアメット ファーマスーティカルズ,インコーポレイテッド 金属酵素阻害化合物
CN104932538B (zh) * 2015-07-03 2018-02-23 中国计量科学研究院 光机旋转装置

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE121520C (no) *
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
US4649146A (en) * 1983-01-31 1987-03-10 Fujisawa Pharmaceutical Co., Ltd. Thiazole derivatives and pharmaceutical composition comprising the same
FR2625199B1 (fr) * 1987-12-23 1991-03-22 Irceba Derives oxyimino du thiazole, procede de preparation et utilisation en therapeutique
JPH01249760A (ja) * 1988-03-29 1989-10-05 Yamaha Corp ホトクロミック化合物
JPH0291076A (ja) * 1988-09-28 1990-03-30 Tokuyama Soda Co Ltd フォトクロミック性化合物及びその製造方法
TW224461B (no) * 1990-09-18 1994-06-01 Ciba Geigy Ag
JPH06505239A (ja) * 1991-01-31 1994-06-16 ワーナー−ランバート・コンパニー 抗炎症剤として有用な4,6−ジ−第三ブチル−5−ヒドロキシ−1,3−ピリミジンの置換されたヘテロアリール類似体
US5177079A (en) * 1991-01-31 1993-01-05 Warner-Lambert Company 2-substituted-4,6-di-tertiarybutyl-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents
GB9125924D0 (en) * 1991-06-18 1992-02-05 Orion Yhtymae Oy Stereoisomers of an imidazole derivative

Also Published As

Publication number Publication date
CN1044705C (zh) 1999-08-18
HU9503742D0 (en) 1996-02-28
FI960077A0 (fi) 1996-01-08
CZ4196A3 (en) 1996-06-12
FI960077A (fi) 1996-01-08
CA2164876A1 (en) 1995-01-19
IS1742B (is) 2000-02-21
PL179021B1 (pl) 2000-07-31
RU2137763C1 (ru) 1999-09-20
SK159995A3 (en) 1996-06-05
PL312427A1 (en) 1996-04-29
AU7197894A (en) 1995-02-06
AU691191B2 (en) 1998-05-14
HUT74673A (en) 1997-01-28
NO960029D0 (no) 1996-01-04
JPH08512313A (ja) 1996-12-24
BR9406924A (pt) 1996-07-30
CN1126990A (zh) 1996-07-17
SE9302333D0 (sv) 1993-07-06
NZ268690A (en) 1997-11-24
NO305862B1 (no) 1999-08-09
EP0707573A1 (en) 1996-04-24
IS4183A (is) 1995-01-07
WO1995001967A1 (en) 1995-01-19
US5747515A (en) 1998-05-05
NO960029L (no) 1996-01-04

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