NO305862B1 - Nye (1-fenyl-1-heterocyklyl)alkanderivater, farmas°ytisk preparat og anvendelse av derivatene til fremstilling av neurobeskyttende midler - Google Patents

Nye (1-fenyl-1-heterocyklyl)alkanderivater, farmas°ytisk preparat og anvendelse av derivatene til fremstilling av neurobeskyttende midler

Info

Publication number
NO305862B1
NO305862B1 NO960029A NO960029A NO305862B1 NO 305862 B1 NO305862 B1 NO 305862B1 NO 960029 A NO960029 A NO 960029A NO 960029 A NO960029 A NO 960029A NO 305862 B1 NO305862 B1 NO 305862B1
Authority
NO
Norway
Prior art keywords
derivatives
heterocyclyl
phenyl
preparation
new
Prior art date
Application number
NO960029A
Other languages
English (en)
Other versions
NO960029L (no
NO960029D0 (no
Inventor
Bernard Robin Boar
Alan John Cross
Duncan Alastair Gray
Alfred Richard Green
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of NO960029L publication Critical patent/NO960029L/no
Publication of NO960029D0 publication Critical patent/NO960029D0/no
Publication of NO305862B1 publication Critical patent/NO305862B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO960029A 1993-07-06 1996-01-04 Nye (1-fenyl-1-heterocyklyl)alkanderivater, farmas°ytisk preparat og anvendelse av derivatene til fremstilling av neurobeskyttende midler NO305862B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE19939302333A SE9302333D0 (sv) 1993-07-06 1993-07-06 New compounds
PCT/SE1994/000664 WO1995001967A1 (en) 1993-07-06 1994-07-05 Novel (1-phenyl-1-heterocyclyl)alkane derivatives and their use as neuroprotective agents

Publications (3)

Publication Number Publication Date
NO960029L NO960029L (no) 1996-01-04
NO960029D0 NO960029D0 (no) 1996-01-04
NO305862B1 true NO305862B1 (no) 1999-08-09

Family

ID=20390540

Family Applications (1)

Application Number Title Priority Date Filing Date
NO960029A NO305862B1 (no) 1993-07-06 1996-01-04 Nye (1-fenyl-1-heterocyklyl)alkanderivater, farmas°ytisk preparat og anvendelse av derivatene til fremstilling av neurobeskyttende midler

Country Status (18)

Country Link
US (1) US5747515A (no)
EP (1) EP0707573A1 (no)
JP (1) JPH08512313A (no)
CN (1) CN1044705C (no)
AU (1) AU691191B2 (no)
BR (1) BR9406924A (no)
CA (1) CA2164876A1 (no)
CZ (1) CZ4196A3 (no)
FI (1) FI960077A (no)
HU (1) HUT74673A (no)
IS (1) IS1742B (no)
NO (1) NO305862B1 (no)
NZ (1) NZ268690A (no)
PL (1) PL179021B1 (no)
RU (1) RU2137763C1 (no)
SE (1) SE9302333D0 (no)
SK (1) SK281025B6 (no)
WO (1) WO1995001967A1 (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2774596B1 (fr) * 1998-02-11 2000-03-17 Rhone Poulenc Rorer Sa Utilisation de composes selenies dans la prevention et le traitement de la maladie d'alzheimer
US6573289B1 (en) 1998-04-23 2003-06-03 Takeda Chemical Industries, Ltd. Naphthalene derivatives, their production and use
US6503935B1 (en) 1998-08-07 2003-01-07 Abbott Laboratories Imidazoles and related compounds as α1A agonists
US6156775A (en) * 1999-03-01 2000-12-05 Novartis Ag Use of fluorinated triazoles in treating affective and attention disorders
AU5566400A (en) 1999-06-22 2001-01-09 Takeda Chemical Industries Ltd. Process for the preparation of imidazole derivatives
SE9904177D0 (sv) * 1999-11-18 1999-11-18 Astra Ab Novel compounds
WO2008064317A1 (en) * 2006-11-22 2008-05-29 University Of Medicine And Dentistry Of New Jersey Lipophilic opioid receptor active compounds
AU2012300275A1 (en) * 2011-08-30 2014-03-06 Innocrin Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
CN104932538B (zh) * 2015-07-03 2018-02-23 中国计量科学研究院 光机旋转装置

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE121520C (no) *
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
US4649146A (en) * 1983-01-31 1987-03-10 Fujisawa Pharmaceutical Co., Ltd. Thiazole derivatives and pharmaceutical composition comprising the same
FR2625199B1 (fr) * 1987-12-23 1991-03-22 Irceba Derives oxyimino du thiazole, procede de preparation et utilisation en therapeutique
JPH01249760A (ja) * 1988-03-29 1989-10-05 Yamaha Corp ホトクロミック化合物
JPH0291076A (ja) * 1988-09-28 1990-03-30 Tokuyama Soda Co Ltd フォトクロミック性化合物及びその製造方法
TW224461B (no) * 1990-09-18 1994-06-01 Ciba Geigy Ag
US5177079A (en) * 1991-01-31 1993-01-05 Warner-Lambert Company 2-substituted-4,6-di-tertiarybutyl-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents
EP0569493A4 (en) * 1991-01-31 1993-11-24 Warner-Lambert Company Substituted 4,6-di-tertiary-butyl-5-hydroxy-pyrimidines
GB9125924D0 (en) * 1991-06-18 1992-02-05 Orion Yhtymae Oy Stereoisomers of an imidazole derivative

Also Published As

Publication number Publication date
CN1126990A (zh) 1996-07-17
WO1995001967A1 (en) 1995-01-19
NZ268690A (en) 1997-11-24
FI960077A0 (fi) 1996-01-08
CA2164876A1 (en) 1995-01-19
PL312427A1 (en) 1996-04-29
SE9302333D0 (sv) 1993-07-06
JPH08512313A (ja) 1996-12-24
PL179021B1 (pl) 2000-07-31
EP0707573A1 (en) 1996-04-24
CN1044705C (zh) 1999-08-18
RU2137763C1 (ru) 1999-09-20
FI960077A (fi) 1996-01-08
AU7197894A (en) 1995-02-06
IS1742B (is) 2000-02-21
BR9406924A (pt) 1996-07-30
HUT74673A (en) 1997-01-28
CZ4196A3 (en) 1996-06-12
AU691191B2 (en) 1998-05-14
SK281025B6 (sk) 2000-11-07
US5747515A (en) 1998-05-05
SK159995A3 (en) 1996-06-05
NO960029L (no) 1996-01-04
IS4183A (is) 1995-01-07
NO960029D0 (no) 1996-01-04
HU9503742D0 (en) 1996-02-28

Similar Documents

Publication Publication Date Title
NO306401B1 (no) Oksazolidindionderivater, farmasöytisk preparat inneholdende slike derivater, og deres anvendelse
NO934146D0 (no) Nye derivater av tiopyranopyrrol, deres fremstilling og farmas!ytiske preparater inneholdende forbindelsene
NO307707B1 (no) Spiroazabicykliske forbindelser, farmasøytisk preparat inneholdende slike forbindelser og anvendelse derav
NO304074B1 (no) Nye steroidestere, farmasöytisk preparat inneholdende disse forbindelsene og deres anvendelse
NO307827B1 (no) Benzoksazol- og pyridinderivater, anvendelse av dem og farmasøytisk preparat inneholdende dem
NO304073B1 (no) Nye steroider, farmasöytisk preparat inneholdende disse forbindelsene og deres anvendelse
NO942316D0 (no) Isatinderivater, fremgangsmåter for deres fremstilling og farmasöytisk preparat omfattende slike derivater
NO2009028I1 (no) Kinazolin-derivater, anvendelse og fremstilling derav, samt farmasøytisk preparat
NO996433D0 (no) Nye formuleringer av legemidler, fremgangsmåter for fremstilling derav og fremgangsmåter for anvendelse derav
NO961274D0 (no) Azolderivat og farmasöytiske preparat derav
NO308660B1 (no) Nye 2,3-diketopiperazin-derivater eller deres salter, anvendelse derav og farmasøytisk preparat inneholdende slike
NO924768L (no) Farmasoeytisk preparat og fremgangsmaate for dets fremstilling
NO934723L (no) Nye derivater av taksolanaloger, deres fremstilling og preparater inneholdende derivatene
NO954942L (no) Nye erytromycinderivater, fremgangsmåte for deres fremstilling og anvendelse av derivatene som legemidler
NO944700D0 (no) Nye tienotiazinderivater, fremgangsmåte for fremstilling derav samt farmasöytiske preparater inneholdende forbindelsene
NO952677D0 (no) Nye dihydropyrrolopyridinon- og oksazolopyridinonforbindelser, deres fremstilling og farmasöytiske preparater
NO303388B1 (no) Indolderivater, farmas°ytisk preparat inneholdende dem og mellomprodukter ved fremstilling av dem
NO985368L (no) Substituerte imidazolidinderivater, deres fremstilling, deres anvendelse og farmas°ytiske preparater inneholdende forbindelsene
NO934372D0 (no) Nye forbindelser og farmas!ytisk preparat derav
NO960722D0 (no) Benzazepinderivat, farmasöytisk preparat inneholdende dette, og mellomprodukter for dette
NO305955B1 (no) Nye (1-heteroazolyl-1-heterocyklyl)alkanderivater, mellomprodukter for deres fremstilling, farmasoeytisk preparat inneholdende slike derivater, og deres anvendelse til fremstilling av neurobeskyttende midler
NO307510B1 (no) Bicykliske aromatiske forbindelser, deres anvendelse og farmasøytiske og kosmetiske preparater derav
DK162491D0 (da) Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne
DK132790A (da) Antiinflammatoriske og analgetiske forbindelser, praeparater deraf og metoder til fremstilling og anvendelse deraf
NO305862B1 (no) Nye (1-fenyl-1-heterocyklyl)alkanderivater, farmas°ytisk preparat og anvendelse av derivatene til fremstilling av neurobeskyttende midler

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN JANUARY 2002