SK280030B6 - Spôsob výroby opticky aktívnych derivátov cyklobut - Google Patents

Spôsob výroby opticky aktívnych derivátov cyklobut Download PDF

Info

Publication number
SK280030B6
SK280030B6 SK1547-91A SK154791A SK280030B6 SK 280030 B6 SK280030 B6 SK 280030B6 SK 154791 A SK154791 A SK 154791A SK 280030 B6 SK280030 B6 SK 280030B6
Authority
SK
Slovakia
Prior art keywords
formula
group
carbon atoms
compound
groups
Prior art date
Application number
SK1547-91A
Other languages
English (en)
Slovak (sk)
Inventor
Ahmad Saleem
Original Assignee
E. R.Squibb & Sons
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E. R.Squibb & Sons filed Critical E. R.Squibb & Sons
Publication of SK280030B6 publication Critical patent/SK280030B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/42—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C67/347—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/78—Benzoic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Furan Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SK1547-91A 1990-05-24 1991-05-23 Spôsob výroby opticky aktívnych derivátov cyklobut SK280030B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52862690A 1990-05-24 1990-05-24

Publications (1)

Publication Number Publication Date
SK280030B6 true SK280030B6 (sk) 1999-07-12

Family

ID=24106474

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1547-91A SK280030B6 (sk) 1990-05-24 1991-05-23 Spôsob výroby opticky aktívnych derivátov cyklobut

Country Status (16)

Country Link
EP (1) EP0458643B1 (de)
JP (1) JPH05339192A (de)
KR (1) KR100189598B1 (de)
AT (1) ATE130840T1 (de)
CA (1) CA2041950A1 (de)
CZ (1) CZ281339B6 (de)
DE (1) DE69114911T2 (de)
DK (1) DK0458643T3 (de)
ES (1) ES2080898T3 (de)
FI (1) FI102274B (de)
GR (1) GR3018840T3 (de)
HU (1) HU213234B (de)
IE (1) IE72143B1 (de)
NO (1) NO175589C (de)
RU (1) RU2012555C1 (de)
SK (1) SK280030B6 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5412134A (en) * 1992-05-26 1995-05-02 E. R. Squibb & Sons, Inc. Process for preparing diprotected 2,3-hydroxymethyl cyclobutanol
US5580973A (en) * 1994-01-07 1996-12-03 Lee-Ruff; Edward Process for preparing optically active nucleosides from chiral cyclobutanones
AU4890096A (en) * 1995-03-10 1996-10-02 Nissan Chemical Industries Ltd. Titanium catalyst, organotitanium reaction reagent, processes for producing these, and method of reaction using these
CA2242218C (en) * 1997-07-22 2007-09-04 Lonza Ag Process for preparing cyclobutane-1,2-dicarboxylic esters
GB0526279D0 (en) * 2005-12-23 2006-02-01 Givaudan Sa Improvements in or related to organic compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3317586A (en) * 1964-08-17 1967-05-02 Eastman Kodak Co Dialkoxycyclobutane carboxylic acid esters and their preparation
US5723609A (en) * 1988-03-30 1998-03-03 E. R. Squibb & Sons, Inc. Bis (hydroxymethyl) cyclobutyl purines
AU622926B2 (en) * 1988-09-09 1992-04-30 Nippon Kayaku Kabushiki Kaisha Pyrimidine or purine cyclobutane derivatives

Also Published As

Publication number Publication date
NO911994L (no) 1991-11-25
EP0458643B1 (de) 1995-11-29
NO175589B (no) 1994-07-25
NO175589C (no) 1994-11-02
FI102274B1 (fi) 1998-11-13
KR100189598B1 (ko) 1999-06-01
ATE130840T1 (de) 1995-12-15
FI102274B (fi) 1998-11-13
KR910019944A (ko) 1991-12-19
IE911518A1 (en) 1991-12-04
EP0458643A2 (de) 1991-11-27
RU2012555C1 (ru) 1994-05-15
CA2041950A1 (en) 1991-11-25
EP0458643A3 (en) 1993-06-16
DK0458643T3 (da) 1995-12-27
HUT57695A (en) 1991-12-30
CZ281339B6 (cs) 1996-08-14
GR3018840T3 (en) 1996-04-30
HU213234B (en) 1997-03-28
ES2080898T3 (es) 1996-02-16
FI912501A0 (fi) 1991-05-23
JPH05339192A (ja) 1993-12-21
FI912501A (fi) 1991-11-25
CS154791A3 (en) 1992-01-15
IE72143B1 (en) 1997-03-26
DE69114911D1 (de) 1996-01-11
NO911994D0 (no) 1991-05-23
DE69114911T2 (de) 1996-04-18

Similar Documents

Publication Publication Date Title
US5457227A (en) Process for the preparation of 1,3-dioxane derivatives useful in the preparation of HMG-CoA reductase inhibitors
Alibés et al. Highly efficient and diastereoselective approaches to (+)-and (−)-grandisol
BE1003843A4 (fr) Procede stereospecifique pour la preparation des enantiomeres de la furo (3,4-c) pyridine et composes ainsi obtenus.
SK280030B6 (sk) Spôsob výroby opticky aktívnych derivátov cyklobut
US4851427A (en) Pyrrole analogs of mevalonolactone, derivatives thereof and pharmaceutical use
Shimizu et al. Synthesis and absolute configuration of optically active selenoxides. X-Ray molecular structure of (–) se-4-menthyloxycarbonylphenyl 2, 4, 6-tri-isopropylphenyl selenoxide
FR2473516A1 (fr) Nouveaux derives 4,5-insatures d'acide prostanoique, utiles notamment comme antisecretoires gastriques et leur procede de preparation
Chong et al. Facile preparation of (2R, 3S)-and (2S, 3R)-3-[[(4-bromobenzyl) oxy] methyl] oxirane-2-methanol via asymmetric epoxidation
US5504107A (en) Optically pure 4-alkenyl- or 4-alkanyl-2-hydroxytetronic acids and pharmaceutical use thereof
US5233076A (en) Process for preparing an optically active cyclobutanone, an intermediate in the synthesis of an optically active cyclobutane nucleoside
JPS63192767A (ja) テトラヒドロフラン誘導体化合物、その製造法及びそれを含有する製薬組成物
CA1282425C (en) Process for preparing hmg-coa reductase inhibitors with a 3,5-dihydroxypentanoate subunit
US5344962A (en) Intermediates in the synthesis of an optically active cyclobutane nucleoside
US5049578A (en) 1-aroyl or 1-acyl-2-2pyrrolidinyl-3,5-dihydroxy alkanoic and alkenoic acids, salts, esters and lactones
US4473709A (en) Pyrethroid intermediates and process
US5208258A (en) Antihypercholesterolemic compounds and synthesis thereof
Montgomery et al. De novo synthesis of carbohydrates by stereoselective aldol reaction: l-cladinose
US5169959A (en) Free radical-catalyzed synthesis of benzoprostacyclins
US4739082A (en) Enantiomerically pure mono acetal-protected diols, their preparation and use
US4603213A (en) Total synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
Gypser et al. d‐Erythronolactone and 2, 3‐O‐Isopropylidene‐l‐erythrose as C4 Building Units: An Efficient Synthesis of both Enantiomers of endo‐Brevicomin and its 7‐Vinyl Analogues
Matsuo et al. Concise formal synthesis of (S)-gregatin B
US5149835A (en) Substituted mevalonolactones, and methods for stereoselective preparation thereof and desmethyl homologues thereof
US4861910A (en) Process for the production of substituted 2-oxocyclohexaneacetic acid esters
US4362872A (en) 6,6-Difluoro-5-hydroxy-4-(3-oxoalk-1-enyl)hexahydro cyclopenta[b] furan-2-ols