SK279048B6 - Spôsob génovotechnologickej výroby s-(+)-2,2--dime - Google Patents

Spôsob génovotechnologickej výroby s-(+)-2,2--dime Download PDF

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Publication number
SK279048B6
SK279048B6 SK2323-92A SK232392A SK279048B6 SK 279048 B6 SK279048 B6 SK 279048B6 SK 232392 A SK232392 A SK 232392A SK 279048 B6 SK279048 B6 SK 279048B6
Authority
SK
Slovakia
Prior art keywords
dna
microorganisms
hybrid plasmid
dna fragment
transformed
Prior art date
Application number
SK2323-92A
Other languages
English (en)
Slovak (sk)
Other versions
SK232392A3 (en
Inventor
Thomas Zimmermann
Karen Robins
Olwen M. Birch
Elisabeth B�Hlen
Original Assignee
Lonza A.G.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza A.G. filed Critical Lonza A.G.
Publication of SK232392A3 publication Critical patent/SK232392A3/sk
Publication of SK279048B6 publication Critical patent/SK279048B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/06Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
SK2323-92A 1991-07-26 1992-07-24 Spôsob génovotechnologickej výroby s-(+)-2,2--dime SK279048B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH224791 1991-07-26

Publications (2)

Publication Number Publication Date
SK232392A3 SK232392A3 (en) 1995-11-08
SK279048B6 true SK279048B6 (sk) 1998-06-03

Family

ID=4229309

Family Applications (1)

Application Number Title Priority Date Filing Date
SK2323-92A SK279048B6 (sk) 1991-07-26 1992-07-24 Spôsob génovotechnologickej výroby s-(+)-2,2--dime

Country Status (17)

Country Link
US (1) US5427934A (ru)
EP (1) EP0524604B1 (ru)
JP (1) JP3217859B2 (ru)
AT (1) ATE172248T1 (ru)
CA (1) CA2074681C (ru)
CZ (1) CZ279498B6 (ru)
DE (1) DE59209523D1 (ru)
DK (1) DK0524604T3 (ru)
ES (1) ES2124714T3 (ru)
HU (1) HU215231B (ru)
IE (1) IE922406A1 (ru)
IL (1) IL102643A0 (ru)
MX (1) MX9204350A (ru)
PL (1) PL170598B1 (ru)
RO (1) RO114152B1 (ru)
RU (1) RU2126450C1 (ru)
SK (1) SK279048B6 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG72731A1 (en) * 1996-03-15 2000-05-23 Nabe Seiyaku Co Ltd Process for preparing optically active trans-3-phenylglycidamide compounds
CA2447788A1 (en) * 2001-05-18 2002-11-28 Ranbaxy Laboratories Limited Process for the preparation of amorphous cilastatin sodium
KR100511534B1 (ko) * 2002-07-05 2005-08-31 임광민 아미드 화합물의 새로운 제조방법
KR100650797B1 (ko) 2005-12-12 2006-11-27 (주)케미코월드 광학활성 사이클로프로판 카복사미드의 제조방법
CN102250934A (zh) * 2010-05-17 2011-11-23 浙江海正药业股份有限公司 一种酰胺水解酶的高效表达及应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2511867A (en) * 1949-12-19 1950-06-20 Method fob separating enantiomers
US3897308A (en) * 1971-05-07 1975-07-29 Exxon Research Engineering Co Immobilized enzymes and method for preparation
JPS5685298A (en) * 1979-12-14 1981-07-11 Asahi Chem Ind Co Ltd Preparation of 7-aminocephem compound
EP0048301A1 (en) * 1980-09-24 1982-03-31 Merck & Co. Inc. 2-(Cyclopropane-carboxamido)-2-alkenoic acids, their esters and salts, and antibacterial compositions comprising the same and a thienamycin-type compound
JPS6056936A (ja) * 1983-09-06 1985-04-02 Sumitomo Chem Co Ltd 光学活性2,2−ジメチルシクロプロパンカルボン酸及びその誘導体の製法
EP0488999B1 (en) * 1986-04-16 1997-07-09 Sumitomo Chemical Company Limited A method for producing optically active cyclopropane carboxylic acid
DE3929570A1 (de) * 1989-09-06 1991-03-07 Degussa Mikrobiologisch hergestellte n-acyl-l-prolin-acylase, verfahren zu ihrer gewinnung und ihre verwendung
FR2655660B1 (fr) * 1989-12-11 1992-03-20 Rhone Poulenc Sante Nouveaux polypeptides, sequences d'adn permettant leur expression, procede de preparation et leur utilisation.
CA2056840A1 (en) * 1990-12-17 1992-06-18 Thomas Meul Process for the production of dimethylcyclopropanecarboxylic acid
RU2096460C1 (ru) * 1991-03-06 1997-11-20 Лонца Аг Способ получения s-(+)-2,2-диметилциклопропанкарбоксамида, штаммы бактерий comamonas acidovorans, pseudomonas sp., bacterium sp., предназначенные для получения s-(+)-2,2-диметилциклопропанкарбоксамида (варианты)

Also Published As

Publication number Publication date
HUT67687A (en) 1995-04-28
DE59209523D1 (de) 1998-11-19
HU215231B (hu) 1999-01-28
HU9202439D0 (en) 1992-10-28
EP0524604B1 (de) 1998-10-14
EP0524604A2 (de) 1993-01-27
RU2126450C1 (ru) 1999-02-20
ATE172248T1 (de) 1998-10-15
RO114152B1 (ro) 1999-01-29
CA2074681A1 (en) 1993-01-27
IE922406A1 (en) 1993-01-27
JP3217859B2 (ja) 2001-10-15
ES2124714T3 (es) 1999-02-16
JPH05236993A (ja) 1993-09-17
SK232392A3 (en) 1995-11-08
PL170598B1 (pl) 1997-01-31
MX9204350A (es) 1993-02-01
US5427934A (en) 1995-06-27
EP0524604A3 (ru) 1994-05-04
CA2074681C (en) 2000-11-28
DK0524604T3 (da) 1999-06-23
CZ232392A3 (en) 1993-02-17
PL295408A1 (en) 1993-03-22
IL102643A0 (en) 1993-01-14
CZ279498B6 (cs) 1995-05-17

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MK4A Patent expired

Expiry date: 20120724