SK19398A3 - Allergen-xcd32 fusion proteins - Google Patents

Allergen-xcd32 fusion proteins Download PDF

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Publication number
SK19398A3
SK19398A3 SK193-98A SK19398A SK19398A3 SK 19398 A3 SK19398 A3 SK 19398A3 SK 19398 A SK19398 A SK 19398A SK 19398 A3 SK19398 A3 SK 19398A3
Authority
SK
Slovakia
Prior art keywords
fusion protein
cells
der
antigen
human
Prior art date
Application number
SK193-98A
Other languages
English (en)
Slovak (sk)
Inventor
Geert C Mudde
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SK19398A3 publication Critical patent/SK19398A3/sk

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43531Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Insects & Arthropods (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Pulmonology (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SK193-98A 1995-08-16 1996-08-16 Allergen-xcd32 fusion proteins SK19398A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9516760.7A GB9516760D0 (en) 1995-08-16 1995-08-16 Organic compounds
PCT/EP1996/003616 WO1997007218A1 (en) 1995-08-16 1996-08-16 Allergen-xcd32 fusion proteins

Publications (1)

Publication Number Publication Date
SK19398A3 true SK19398A3 (en) 1998-09-09

Family

ID=10779307

Family Applications (1)

Application Number Title Priority Date Filing Date
SK193-98A SK19398A3 (en) 1995-08-16 1996-08-16 Allergen-xcd32 fusion proteins

Country Status (16)

Country Link
EP (1) EP0846178A1 (no)
JP (1) JPH11513025A (no)
KR (1) KR19990036440A (no)
CN (1) CN1193353A (no)
AU (1) AU6873596A (no)
BR (1) BR9610239A (no)
CA (1) CA2227795A1 (no)
CZ (1) CZ43798A3 (no)
GB (1) GB9516760D0 (no)
HU (1) HUP9802349A3 (no)
IL (1) IL122898A0 (no)
NO (1) NO980566D0 (no)
PL (1) PL324897A1 (no)
SK (1) SK19398A3 (no)
TR (1) TR199800214T1 (no)
WO (1) WO1997007218A1 (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9724531D0 (en) 1997-11-19 1998-01-21 Smithkline Biolog Novel compounds
AU750358B2 (en) 1997-12-02 2002-07-18 Medarex, Inc. Cells expressing anti-Fc receptor binding components
EP1221317A1 (en) * 2000-12-28 2002-07-10 SHAN-Beteiligungsgesellschaft m.b.H. Vaccines containing hybrid polypeptides consisting of at least two different allergenic proteins
US8029803B2 (en) 2002-06-20 2011-10-04 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
US8025873B2 (en) 2002-06-20 2011-09-27 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
US8007805B2 (en) 2003-08-08 2011-08-30 Paladin Labs, Inc. Chimeric antigens for breaking host tolerance to foreign antigens
BG65715B1 (bg) * 2003-09-04 2009-08-31 Чавдар ВАСИЛЕВ Средство за селективно подтискане на патологични днк - специфични в клетки
BG65954B1 (bg) * 2005-01-05 2010-07-30 Чавдар ВАСИЛЕВ Средство за селективно подтискане активността на патологични автореактивни в-клетки
US9636415B2 (en) 2006-03-03 2017-05-02 S-Target Therapeutics Gmbh Bispecific molecule binding TLR9 and CD32 and comprising a T cell epitope for treatment of allergies
EP1829895A1 (en) * 2006-03-03 2007-09-05 f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. Bispecific molecule binding TLR9 and CD32 and comprising a T cell epitope for treatment of allergies
LT2861240T (lt) 2012-06-15 2021-01-25 Immunomic Therapeutics, Inc. Nukleorūgštys skirtos alergijoms gydyti
RU2650709C2 (ru) 2012-07-13 2018-04-17 С-Таргет Терапевтикс Гмбх Иммунорегуляторная вакцина
DK2914285T3 (en) * 2012-11-01 2017-02-27 Veterinærinstituttet New fusion proteins for the treatment of allergic diseases
US9005630B2 (en) 2012-11-01 2015-04-14 Veterinaerinstituttet Fusion proteins for the treatment of allergic diseases
CN105407919B (zh) 2013-05-21 2019-08-06 Tyg肿瘤学有限公司 胃泌素肽免疫原性组合物
CN113186167B (zh) * 2021-04-28 2021-11-30 中国食品药品检定研究院 用于测定抗cd20单克隆抗体药物adcp生物学活性的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994024281A1 (en) * 1993-04-14 1994-10-27 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from dermatophagoides (house dust mite)
EP0759782A1 (en) * 1994-05-26 1997-03-05 Innogenetics N.V. New methods and compounds for the selective modulation of antigen-specific t-cell responsiveness

Also Published As

Publication number Publication date
PL324897A1 (en) 1998-06-22
CZ43798A3 (cs) 1998-06-17
IL122898A0 (en) 1998-08-16
GB9516760D0 (en) 1995-10-18
CN1193353A (zh) 1998-09-16
JPH11513025A (ja) 1999-11-09
AU6873596A (en) 1997-03-12
TR199800214T1 (xx) 1998-06-22
KR19990036440A (ko) 1999-05-25
HUP9802349A3 (en) 1999-04-28
MX9801253A (es) 1998-05-31
NO980566L (no) 1998-02-10
WO1997007218A1 (en) 1997-02-27
BR9610239A (pt) 1999-06-15
HUP9802349A2 (hu) 1999-01-28
NO980566D0 (no) 1998-02-10
CA2227795A1 (en) 1997-02-27
EP0846178A1 (en) 1998-06-10

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