HUP9802349A2 - Allergén - XCD32 fúziós fehérjék és eljárás allergiaellenes gyógyszerkészítmény előállítására - Google Patents

Allergén - XCD32 fúziós fehérjék és eljárás allergiaellenes gyógyszerkészítmény előállítására

Info

Publication number
HUP9802349A2
HUP9802349A2 HU9802349A HUP9802349A HUP9802349A2 HU P9802349 A2 HUP9802349 A2 HU P9802349A2 HU 9802349 A HU9802349 A HU 9802349A HU P9802349 A HUP9802349 A HU P9802349A HU P9802349 A2 HUP9802349 A2 HU P9802349A2
Authority
HU
Hungary
Prior art keywords
xcd32
allergenic
allergen
fusion proteins
pharmaceutical product
Prior art date
Application number
HU9802349A
Other languages
English (en)
Inventor
Geert C. Mudde
Original Assignee
Novartis Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag. filed Critical Novartis Ag.
Publication of HUP9802349A2 publication Critical patent/HUP9802349A2/hu
Publication of HUP9802349A3 publication Critical patent/HUP9802349A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43531—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Insects & Arthropods (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

A találmány tárgya fúziós prőtein, amely a) egy vagy több antigént és b) az emberi Fcg-receptőr-II-vel (Fcg- RII) (CD32) kölcsönhatásba lépőláncőt tartalmaz. ŕ
HU9802349A 1995-08-16 1996-08-16 Allergen-xcd32 fusion proteins and process of making anti-allergenic pharmaceutical product HUP9802349A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9516760.7A GB9516760D0 (en) 1995-08-16 1995-08-16 Organic compounds

Publications (2)

Publication Number Publication Date
HUP9802349A2 true HUP9802349A2 (hu) 1999-01-28
HUP9802349A3 HUP9802349A3 (en) 1999-04-28

Family

ID=10779307

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9802349A HUP9802349A3 (en) 1995-08-16 1996-08-16 Allergen-xcd32 fusion proteins and process of making anti-allergenic pharmaceutical product

Country Status (16)

Country Link
EP (1) EP0846178A1 (hu)
JP (1) JPH11513025A (hu)
KR (1) KR19990036440A (hu)
CN (1) CN1193353A (hu)
AU (1) AU6873596A (hu)
BR (1) BR9610239A (hu)
CA (1) CA2227795A1 (hu)
CZ (1) CZ43798A3 (hu)
GB (1) GB9516760D0 (hu)
HU (1) HUP9802349A3 (hu)
IL (1) IL122898A0 (hu)
NO (1) NO980566L (hu)
PL (1) PL324897A1 (hu)
SK (1) SK19398A3 (hu)
TR (1) TR199800214T1 (hu)
WO (1) WO1997007218A1 (hu)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9724531D0 (en) 1997-11-19 1998-01-21 Smithkline Biolog Novel compounds
AU750358B2 (en) 1997-12-02 2002-07-18 Medarex, Inc. Cells expressing anti-Fc receptor binding components
EP1221317A1 (en) * 2000-12-28 2002-07-10 SHAN-Beteiligungsgesellschaft m.b.H. Vaccines containing hybrid polypeptides consisting of at least two different allergenic proteins
US8029803B2 (en) 2002-06-20 2011-10-04 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
US8025873B2 (en) 2002-06-20 2011-09-27 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
US8007805B2 (en) 2003-08-08 2011-08-30 Paladin Labs, Inc. Chimeric antigens for breaking host tolerance to foreign antigens
BG65715B1 (bg) * 2003-09-04 2009-08-31 Чавдар ВАСИЛЕВ Средство за селективно подтискане на патологични днк - специфични в клетки
BG65954B1 (bg) * 2005-01-05 2010-07-30 Чавдар ВАСИЛЕВ Средство за селективно подтискане активността на патологични автореактивни в-клетки
US9636415B2 (en) 2006-03-03 2017-05-02 S-Target Therapeutics Gmbh Bispecific molecule binding TLR9 and CD32 and comprising a T cell epitope for treatment of allergies
EP1829895A1 (en) * 2006-03-03 2007-09-05 f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. Bispecific molecule binding TLR9 and CD32 and comprising a T cell epitope for treatment of allergies
BR112014031327B1 (pt) 2012-06-15 2022-02-01 Immunomic Therapeutics, Inc Moléculas de ácido nucleico para o tratamento de alergias
EP2872169B1 (en) 2012-07-13 2021-09-01 S-TARget therapeutics GmbH Immunoregulatory vaccine
US9005630B2 (en) 2012-11-01 2015-04-14 Veterinaerinstituttet Fusion proteins for the treatment of allergic diseases
DK2914285T3 (en) * 2012-11-01 2017-02-27 Veterinærinstituttet New fusion proteins for the treatment of allergic diseases
ES2665780T3 (es) 2013-05-21 2018-04-27 Tyg Oncology Ltd. Composición inmunogénica de péptido de gastrina
CN113186167B (zh) * 2021-04-28 2021-11-30 中国食品药品检定研究院 用于测定抗cd20单克隆抗体药物adcp生物学活性的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994024281A1 (en) * 1993-04-14 1994-10-27 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from dermatophagoides (house dust mite)
WO1995032734A1 (en) * 1994-05-26 1995-12-07 Innogenetics N.V. New methods and compounds for the selective modulation of antigen-specific t-cell responsiveness

Also Published As

Publication number Publication date
CN1193353A (zh) 1998-09-16
CZ43798A3 (cs) 1998-06-17
BR9610239A (pt) 1999-06-15
HUP9802349A3 (en) 1999-04-28
AU6873596A (en) 1997-03-12
KR19990036440A (ko) 1999-05-25
NO980566D0 (no) 1998-02-10
CA2227795A1 (en) 1997-02-27
NO980566L (no) 1998-02-10
TR199800214T1 (xx) 1998-06-22
SK19398A3 (en) 1998-09-09
IL122898A0 (en) 1998-08-16
PL324897A1 (en) 1998-06-22
GB9516760D0 (en) 1995-10-18
EP0846178A1 (en) 1998-06-10
WO1997007218A1 (en) 1997-02-27
JPH11513025A (ja) 1999-11-09
MX9801253A (es) 1998-05-31

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