SK162498A3 - Substituted amidinobenzene derivatives and medicinal compositions thereof - Google Patents

Substituted amidinobenzene derivatives and medicinal compositions thereof Download PDF

Info

Publication number
SK162498A3
SK162498A3 SK1624-98A SK162498A SK162498A3 SK 162498 A3 SK162498 A3 SK 162498A3 SK 162498 A SK162498 A SK 162498A SK 162498 A3 SK162498 A3 SK 162498A3
Authority
SK
Slovakia
Prior art keywords
group
alkoxycarbonyl
vivo
compound
oxo
Prior art date
Application number
SK1624-98A
Other languages
English (en)
Slovak (sk)
Inventor
Yuzo Matsumoto
Seijiro Akamatsu
Masato Ichihara
Tomihisa Kawasaki
Seiji Kaku
Isao Yanagisawa
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SK162498A3 publication Critical patent/SK162498A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK1624-98A 1996-05-30 1997-05-28 Substituted amidinobenzene derivatives and medicinal compositions thereof SK162498A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP13727396 1996-05-30
PCT/JP1997/001804 WO1997045413A1 (fr) 1996-05-30 1997-05-28 Derives amidinobenzene substitue et compositions les comportant

Publications (1)

Publication Number Publication Date
SK162498A3 true SK162498A3 (en) 1999-06-11

Family

ID=15194827

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1624-98A SK162498A3 (en) 1996-05-30 1997-05-28 Substituted amidinobenzene derivatives and medicinal compositions thereof

Country Status (18)

Country Link
US (1) US6057324A (xx)
EP (1) EP0905129A4 (xx)
KR (1) KR20000016164A (xx)
CN (1) CN1221405A (xx)
AR (1) AR008374A1 (xx)
AU (1) AU720233B2 (xx)
BR (1) BR9709277A (xx)
CA (1) CA2250038A1 (xx)
CZ (1) CZ389698A3 (xx)
HU (1) HUP9903539A3 (xx)
ID (1) ID16991A (xx)
NO (1) NO312097B1 (xx)
PL (1) PL330204A1 (xx)
RU (1) RU2158263C2 (xx)
SK (1) SK162498A3 (xx)
TW (1) TW403745B (xx)
WO (1) WO1997045413A1 (xx)
ZA (1) ZA974422B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7635698B2 (en) 2004-12-29 2009-12-22 Millennium Pharmaceuticals, Inc. Compounds useful as chemokine receptor antagonists
WO2006071875A1 (en) * 2004-12-29 2006-07-06 Millennium Pharmaceuticals, Inc. Compounds useful as chemokine receptor antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2915892A (en) * 1991-11-14 1993-06-15 Glaxo Group Limited Piperidine acetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation
WO1996024583A1 (fr) * 1995-02-10 1996-08-15 Yamanouchi Pharmaceutical Co., Ltd. Nouveaux derives de benzamidine et leur composition medicinale
JPH0987280A (ja) * 1995-09-28 1997-03-31 Yamanouchi Pharmaceut Co Ltd オキソピペラジン誘導体又はその塩

Also Published As

Publication number Publication date
AU2975997A (en) 1998-01-05
CZ389698A3 (cs) 1999-02-17
BR9709277A (pt) 1999-08-10
KR20000016164A (ko) 2000-03-25
RU2158263C2 (ru) 2000-10-27
TW403745B (en) 2000-09-01
CN1221405A (zh) 1999-06-30
ID16991A (id) 1997-11-27
PL330204A1 (en) 1999-04-26
NO985572D0 (no) 1998-11-27
ZA974422B (en) 1997-12-22
EP0905129A4 (en) 2000-03-15
HUP9903539A3 (en) 2002-01-28
EP0905129A1 (en) 1999-03-31
HUP9903539A2 (hu) 2000-05-28
NO312097B1 (no) 2002-03-18
WO1997045413A1 (fr) 1997-12-04
AU720233B2 (en) 2000-05-25
US6057324A (en) 2000-05-02
CA2250038A1 (en) 1997-12-04
NO985572L (no) 1999-01-26
AR008374A1 (es) 2000-01-19

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