SK141598A3 - 3-[(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl]-8- -azabicyclo[3.2.1]octane derivatives, their preparation and their application in therapeutics - Google Patents

3-[(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl]-8- -azabicyclo[3.2.1]octane derivatives, their preparation and their application in therapeutics Download PDF

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Publication number
SK141598A3
SK141598A3 SK1415-98A SK141598A SK141598A3 SK 141598 A3 SK141598 A3 SK 141598A3 SK 141598 A SK141598 A SK 141598A SK 141598 A3 SK141598 A3 SK 141598A3
Authority
SK
Slovakia
Prior art keywords
compound
group
general formula
azabicyclo
octane
Prior art date
Application number
SK1415-98A
Other languages
English (en)
Slovak (sk)
Inventor
Mireille Sevrin
Benoit Marabout
Pascal George
Jean-Pierre Merly
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of SK141598A3 publication Critical patent/SK141598A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SK1415-98A 1996-04-12 1997-04-10 3-[(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl]-8- -azabicyclo[3.2.1]octane derivatives, their preparation and their application in therapeutics SK141598A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9604565A FR2747386B1 (fr) 1996-04-12 1996-04-12 Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl] -8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique
PCT/FR1997/000634 WO1997038998A1 (fr) 1996-04-12 1997-04-10 Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl]-8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
SK141598A3 true SK141598A3 (en) 1999-03-12

Family

ID=9491132

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1415-98A SK141598A3 (en) 1996-04-12 1997-04-10 3-[(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl]-8- -azabicyclo[3.2.1]octane derivatives, their preparation and their application in therapeutics

Country Status (22)

Country Link
EP (1) EP0892800A1 (enExample)
JP (1) JP2000512620A (enExample)
KR (1) KR20000005392A (enExample)
CN (1) CN1216046A (enExample)
AR (1) AR008587A1 (enExample)
AU (1) AU2640997A (enExample)
BG (1) BG102779A (enExample)
BR (1) BR9708654A (enExample)
CA (1) CA2251335A1 (enExample)
CO (1) CO4900067A1 (enExample)
CZ (1) CZ326898A3 (enExample)
EE (1) EE9800396A (enExample)
FR (1) FR2747386B1 (enExample)
IL (1) IL126473A0 (enExample)
NO (1) NO984736L (enExample)
NZ (1) NZ332257A (enExample)
PL (1) PL329243A1 (enExample)
SK (1) SK141598A3 (enExample)
TR (1) TR199801839T2 (enExample)
TW (1) TW407158B (enExample)
WO (1) WO1997038998A1 (enExample)
ZA (1) ZA973124B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011525893A (ja) * 2008-06-27 2011-09-29 ハー・ルンドベック・アクチエゼルスカベット 新規のフェノールアミン類およびカテコールアミン類ならびにそのプロドラッグ
WO2018021447A1 (ja) 2016-07-28 2018-02-01 塩野義製薬株式会社 ドーパミンｄ３受容体拮抗作用を有する含窒素縮環化合物
AU2019211806A1 (en) 2018-01-26 2020-07-30 Shionogi & Co., Ltd. Condensed cyclic compound having dopamine D3 receptor antagonism

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU202108B (en) * 1986-07-30 1991-02-28 Sandoz Ag Process for producing pharmaceutical compositions containing serotonine antqgonistic derivatives of indol-carboxylic acid or imidazolyl-methyl-carbazol
EP0306375A1 (fr) * 1987-08-07 1989-03-08 Synthelabo Dérivés de[(pipéridinyl-4)méthyl]-2 tétrahydro-1,2,3,4 isoquinoléine, leur préparation et leur application en thérapeutique
IL89156A (en) * 1988-07-12 1993-05-13 Synthelabo Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics
FR2661178B1 (fr) * 1990-04-24 1993-03-12 Synthelabo Derives de [(tetrahydro-1,2,3,4 isoquinoleinyl-2)methyl]-4 piperidinecarboxylates-1 d'alkyle, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
TR199801839T2 (enExample) 1998-12-21
AU2640997A (en) 1997-11-07
JP2000512620A (ja) 2000-09-26
AR008587A1 (es) 2000-02-09
CA2251335A1 (en) 1997-10-23
CZ326898A3 (cs) 1999-01-13
CO4900067A1 (es) 2000-03-27
NO984736D0 (no) 1998-10-09
BR9708654A (pt) 1999-08-03
EP0892800A1 (fr) 1999-01-27
WO1997038998A1 (fr) 1997-10-23
NZ332257A (en) 1999-03-29
EE9800396A (et) 1999-06-15
IL126473A0 (en) 1999-08-17
KR20000005392A (ko) 2000-01-25
TW407158B (en) 2000-10-01
FR2747386B1 (fr) 1998-05-15
PL329243A1 (en) 1999-03-15
ZA973124B (en) 1997-11-05
FR2747386A1 (fr) 1997-10-17
NO984736L (no) 1998-11-23
BG102779A (en) 1999-09-30
CN1216046A (zh) 1999-05-05

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