SK11812000A3 - Soli paroxetínu, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie - Google Patents

Soli paroxetínu, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie Download PDF

Info

Publication number
SK11812000A3
SK11812000A3 SK1181-2000A SK11812000A SK11812000A3 SK 11812000 A3 SK11812000 A3 SK 11812000A3 SK 11812000 A SK11812000 A SK 11812000A SK 11812000 A3 SK11812000 A3 SK 11812000A3
Authority
SK
Slovakia
Prior art keywords
paroxetine
salt
acid
solution
toluene
Prior art date
Application number
SK1181-2000A
Other languages
English (en)
Slovak (sk)
Inventor
David Crowe
Deirdre O'keeffe
Michael Urquhart
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9802659.4A external-priority patent/GB9802659D0/en
Priority claimed from GBGB9802653.7A external-priority patent/GB9802653D0/en
Priority claimed from GBGB9802640.4A external-priority patent/GB9802640D0/en
Priority claimed from GBGB9802654.5A external-priority patent/GB9802654D0/en
Priority claimed from GBGB9802644.6A external-priority patent/GB9802644D0/en
Priority claimed from GBGB9802657.8A external-priority patent/GB9802657D0/en
Priority claimed from GBGB9802639.6A external-priority patent/GB9802639D0/en
Priority claimed from GBGB9802655.2A external-priority patent/GB9802655D0/en
Priority claimed from GBGB9802658.6A external-priority patent/GB9802658D0/en
Priority claimed from GBGB9802646.1A external-priority patent/GB9802646D0/en
Priority claimed from GBGB9802664.4A external-priority patent/GB9802664D0/en
Priority claimed from GBGB9802698.2A external-priority patent/GB9802698D0/en
Priority claimed from GBGB9802656.0A external-priority patent/GB9802656D0/en
Priority claimed from GBGB9802645.3A external-priority patent/GB9802645D0/en
Priority claimed from GBGB9802661.0A external-priority patent/GB9802661D0/en
Priority claimed from GBGB9802638.8A external-priority patent/GB9802638D0/en
Priority claimed from GBGB9802665.1A external-priority patent/GB9802665D0/en
Priority claimed from GBGB9817317.2A external-priority patent/GB9817317D0/en
Priority claimed from GBGB9817321.4A external-priority patent/GB9817321D0/en
Priority claimed from GBGB9817360.2A external-priority patent/GB9817360D0/en
Priority claimed from GBGB9817359.4A external-priority patent/GB9817359D0/en
Priority claimed from GBGB9817344.6A external-priority patent/GB9817344D0/en
Priority claimed from GBGB9817309.9A external-priority patent/GB9817309D0/en
Priority claimed from GBGB9817340.4A external-priority patent/GB9817340D0/en
Priority claimed from GBGB9817364.4A external-priority patent/GB9817364D0/en
Priority claimed from GBGB9817307.3A external-priority patent/GB9817307D0/en
Priority claimed from GBGB9817322.2A external-priority patent/GB9817322D0/en
Priority claimed from GBGB9817320.6A external-priority patent/GB9817320D0/en
Priority claimed from GBGB9826173.8A external-priority patent/GB9826173D0/en
Priority claimed from GBGB9826172.0A external-priority patent/GB9826172D0/en
Priority claimed from GBGB9827277.6A external-priority patent/GB9827277D0/en
Priority claimed from GBGB9827341.0A external-priority patent/GB9827341D0/en
Priority claimed from GBGB9828775.8A external-priority patent/GB9828775D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of SK11812000A3 publication Critical patent/SK11812000A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK1181-2000A 1998-02-06 1999-02-05 Soli paroxetínu, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie SK11812000A3 (sk)

Applications Claiming Priority (34)

Application Number Priority Date Filing Date Title
GBGB9802640.4A GB9802640D0 (en) 1998-02-06 1998-02-06 Novel compounds
GBGB9802653.7A GB9802653D0 (en) 1998-02-06 1998-02-06 Novel compounds
GBGB9802644.6A GB9802644D0 (en) 1998-02-06 1998-02-06 Novel compounds
GBGB9802665.1A GB9802665D0 (en) 1998-02-06 1998-02-06 Novel compounds
GBGB9802639.6A GB9802639D0 (en) 1998-02-06 1998-02-06 Novel compounds
GBGB9802655.2A GB9802655D0 (en) 1998-02-06 1998-02-06 Novel compounds
GBGB9802658.6A GB9802658D0 (en) 1998-02-06 1998-02-06 Novel compounds
GBGB9802646.1A GB9802646D0 (en) 1998-02-06 1998-02-06 Novel compounds
GBGB9802664.4A GB9802664D0 (en) 1998-02-06 1998-02-06 Novel compounds
GBGB9802698.2A GB9802698D0 (en) 1998-02-06 1998-02-06 Novel compounds
GBGB9802656.0A GB9802656D0 (en) 1998-02-06 1998-02-06 Novel compounds
GBGB9802645.3A GB9802645D0 (en) 1998-02-06 1998-02-06 Novel compounds
GBGB9802661.0A GB9802661D0 (en) 1998-02-06 1998-02-06 Novel compounds
GBGB9802638.8A GB9802638D0 (en) 1998-02-06 1998-02-06 Novel compounds
GBGB9802659.4A GB9802659D0 (en) 1998-02-06 1998-02-06 Novel compounds
GBGB9802654.5A GB9802654D0 (en) 1998-02-06 1998-02-06 Novel compounds
GBGB9802657.8A GB9802657D0 (en) 1998-02-06 1998-02-06 Novel compounds
GBGB9817360.2A GB9817360D0 (en) 1998-08-08 1998-08-08 Novel compounds
GBGB9817359.4A GB9817359D0 (en) 1998-08-08 1998-08-08 Novel compounds
GBGB9817344.6A GB9817344D0 (en) 1998-08-08 1998-08-08 Novel compounds
GBGB9817309.9A GB9817309D0 (en) 1998-08-08 1998-08-08 Novel compounds
GBGB9817340.4A GB9817340D0 (en) 1998-08-08 1998-08-08 Novel compounds
GBGB9817321.4A GB9817321D0 (en) 1998-08-08 1998-08-08 Novel compound
GBGB9817364.4A GB9817364D0 (en) 1998-08-08 1998-08-08 Novel compounds
GBGB9817307.3A GB9817307D0 (en) 1998-08-08 1998-08-08 Novel compound
GBGB9817317.2A GB9817317D0 (en) 1998-08-08 1998-08-08 Novel compounds
GBGB9817320.6A GB9817320D0 (en) 1998-08-10 1998-08-10 Novel compounds
GBGB9817322.2A GB9817322D0 (en) 1998-08-10 1998-08-10 Novel compounds
GBGB9826173.8A GB9826173D0 (en) 1998-11-30 1998-11-30 Novel compounds
GBGB9826172.0A GB9826172D0 (en) 1998-11-30 1998-11-30 Novel compound
GBGB9827277.6A GB9827277D0 (en) 1998-12-11 1998-12-11 Novel compound
GBGB9827341.0A GB9827341D0 (en) 1998-12-11 1998-12-11 Novel compounds
GBGB9828775.8A GB9828775D0 (en) 1998-12-29 1998-12-29 Novel compounds
PCT/GB1999/000380 WO1999040084A1 (fr) 1998-02-06 1999-02-05 Sels de paroxetine

Publications (1)

Publication Number Publication Date
SK11812000A3 true SK11812000A3 (sk) 2001-08-06

Family

ID=27586915

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1181-2000A SK11812000A3 (sk) 1998-02-06 1999-02-05 Soli paroxetínu, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie

Country Status (11)

Country Link
EP (1) EP1053234A1 (fr)
JP (1) JP2002505254A (fr)
KR (1) KR20010040711A (fr)
BG (1) BG104737A (fr)
CA (1) CA2319652A1 (fr)
EA (1) EA200000815A1 (fr)
IL (1) IL137684A0 (fr)
NO (1) NO20003960L (fr)
PL (1) PL342295A1 (fr)
SK (1) SK11812000A3 (fr)
WO (1) WO1999040084A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9814316D0 (en) * 1998-07-02 1998-09-02 Smithkline Beecham Plc Novel compounds
CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
EP1102764A1 (fr) * 1998-08-08 2001-05-30 Smithkline Beecham Plc Sels de paroxetine
GB9827431D0 (en) * 1998-12-11 1999-02-03 Smithkline Beecham Plc Novel compound
AU5078700A (en) * 1999-06-22 2001-01-09 Smithkline Beecham Plc Novel composition
HU226912B1 (en) * 2000-04-07 2010-03-01 Richter Gedeon Nyrt New paroxetin salt and medicament containing it
CN1484642A (zh) * 2001-01-05 2004-03-24 兴奋性氨基酸受体拮抗剂
WO2003020717A1 (fr) * 2001-08-02 2003-03-13 Spurcourt Limited Sel d'isethionate de paroxetine, procede de preparation et utilisation dans le traitement de la depression
KR100672184B1 (ko) 2004-09-21 2007-01-19 주식회사종근당 파록세틴의 콜린산 또는 콜린산 유도체 염
CN108218844B (zh) * 2018-03-08 2021-01-19 合肥科大生物技术有限公司 一种美金刚帕罗西汀共晶盐及其制备方法、药物组合物、应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8430581D0 (en) * 1984-12-04 1985-01-09 Ferrosan As Treatment
ES2058061T3 (es) * 1985-10-25 1994-11-01 Beecham Group Plc Derivado de piperidina, su preparacion y su uso como medicamento.
CA2206592A1 (fr) * 1996-05-30 1997-11-30 Shu-Zhong Wang Methode de preparation de chlorhydrate de paroxetine amorphe
HU221921B1 (hu) * 1996-07-08 2003-02-28 Richter Gedeon Vegyészeti Gyár Rt. N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására

Also Published As

Publication number Publication date
WO1999040084A1 (fr) 1999-08-12
JP2002505254A (ja) 2002-02-19
NO20003960D0 (no) 2000-08-04
NO20003960L (no) 2000-09-25
BG104737A (en) 2001-07-31
EA200000815A1 (ru) 2001-02-26
EP1053234A1 (fr) 2000-11-22
PL342295A1 (en) 2001-06-04
KR20010040711A (ko) 2001-05-15
IL137684A0 (en) 2001-10-31
CA2319652A1 (fr) 1999-08-12

Similar Documents

Publication Publication Date Title
JP2007532548A (ja) バゼドキシフェンアセテートの結晶質多形体
KR20060135866A (ko) 바제독시펜 아세테이트의 결정질 다형체
CZ429599A3 (cs) Sloučeniny 4-fenylpiperidinu
SK20262000A3 (sk) Metánsulfonát paroxetínu v kryštalickej forme, spôsob jeho výroby, farmaceutický prostriedok s jeho obsahom a jeho použitie
SK11812000A3 (sk) Soli paroxetínu, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie
KR100830002B1 (ko) 시부트라민의 무기산염
SK15032000A3 (sk) Maleínan paroxetínu, spôsob jeho výroby a jeho použitie
SK15912000A3 (sk) Askorbát paroxetínu, spôsob jeho výroby a jeho použitie
SK15902000A3 (sk) 10-gáforsulfonát paroxetínu, spôsob jeho výroby a jeho použitie
CZ20002845A3 (cs) Soli paroxetinu
US20040143120A1 (en) Paroxetine maleate
MXPA00007719A (en) Salts of paroxetine
AU2528899A (en) Salts of paroxetine
WO2000008016A1 (fr) Sels de paroxetine
JP2008509155A (ja) 塩酸ピピンドキシフェン一水和物の結晶多形
MXPA00009884A (en) Paroxetine maleate
MXPA00010435A (en) Paroxetine 10-camphorsulfonate for treatment of cns disorders
CZ20003722A3 (cs) Maleat paroxetinu
CZ20003942A3 (cs) Askorbat paroxetinu
CZ20003941A3 (cs) 10-KafrsuIfonat paroxetinu pro léčbu poruch centrálního nervového systému
MXPA00010439A (en) Paroxetine ascorbate
JP2008509148A (ja) 塩酸ピピンドキシフェン一水和物の結晶多形
CZ2012508A3 (cs) Nový oxalát TAPENTADOLU a zpusob jeho prípravy