SK109993A3 - Thiazolidinedione derivatives producing and use thereof - Google Patents

Thiazolidinedione derivatives producing and use thereof Download PDF

Info

Publication number
SK109993A3
SK109993A3 SK1099-93A SK109993A SK109993A3 SK 109993 A3 SK109993 A3 SK 109993A3 SK 109993 A SK109993 A SK 109993A SK 109993 A3 SK109993 A3 SK 109993A3
Authority
SK
Slovakia
Prior art keywords
thiazolidinedione
derivative according
pyridyl
compound
salt
Prior art date
Application number
SK1099-93A
Other languages
English (en)
Slovak (sk)
Inventor
Takashi Sohda
Hitoshi Ikeda
John C Greenfield
Jerry R Colca
Edgar N Petzold
Original Assignee
Upjohn Co
Takeda Chemikal Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=13672917&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK109993(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Upjohn Co, Takeda Chemikal Ind Ltd filed Critical Upjohn Co
Publication of SK109993A3 publication Critical patent/SK109993A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Graft Or Block Polymers (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Lubricants (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SK1099-93A 1991-04-11 1992-04-06 Thiazolidinedione derivatives producing and use thereof SK109993A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7883691 1991-04-11
PCT/US1992/002566 WO1992018501A1 (en) 1991-04-11 1992-04-06 Thiazolidinedione derivatives, production and use thereof

Publications (1)

Publication Number Publication Date
SK109993A3 true SK109993A3 (en) 1994-12-07

Family

ID=13672917

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1099-93A SK109993A3 (en) 1991-04-11 1992-04-06 Thiazolidinedione derivatives producing and use thereof

Country Status (19)

Country Link
EP (1) EP0579733B1 (no)
JP (1) JP3176694B2 (no)
KR (1) KR100249988B1 (no)
AT (1) ATE202352T1 (no)
AU (1) AU1743292A (no)
CA (1) CA2106967C (no)
CZ (1) CZ196693A3 (no)
DE (1) DE69231886T2 (no)
DK (1) DK0579733T3 (no)
ES (1) ES2161692T3 (no)
FI (1) FI934426A (no)
GR (1) GR3036623T3 (no)
HU (1) HUT68370A (no)
MX (1) MX9201637A (no)
NO (1) NO933615D0 (no)
PT (1) PT100366A (no)
SK (1) SK109993A3 (no)
TW (1) TW209864B (no)
WO (1) WO1992018501A1 (no)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4104593A (en) * 1992-05-05 1993-11-29 Upjohn Company, The A process for producing pioglitazone metabolite
TW268952B (no) * 1993-02-26 1996-01-21 Takeda Pharm Industry Co Ltd
IL113313A (en) * 1994-04-11 1999-09-22 Sankyo Co Heterocyclic compounds and pharmaceutical compositions containing the same
US5952509A (en) * 1996-06-27 1999-09-14 Takeda Chemical Industries, Ltd. Production of benzaldehyde compounds
UA67743C2 (uk) 1997-06-18 2004-07-15 Смітклайн Бічам П.Л.С. Фармацевтична композиція, що містить тіазолідиндіон і сульфонілсечовину, для лікування діабету
DZ2937A1 (fr) 1998-11-12 2004-03-15 Smithkline Beecham Plc Compositions nouvelles de sensibilidants à l'insuline.
AU768994B2 (en) 1998-11-12 2004-01-15 Smithkline Beecham Plc Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
GB0014969D0 (en) 2000-06-19 2000-08-09 Smithkline Beecham Plc Novel method of treatment
DE20119200U1 (de) 2001-11-27 2003-04-10 Joh. Winklhofer & Söhne GmbH und Co KG, 81369 München Kettenspanner mit mechanischer Verriegelung
US8268352B2 (en) 2002-08-05 2012-09-18 Torrent Pharmaceuticals Limited Modified release composition for highly soluble drugs
US8216609B2 (en) 2002-08-05 2012-07-10 Torrent Pharmaceuticals Limited Modified release composition of highly soluble drugs
KR100646128B1 (ko) 2005-04-21 2006-11-14 전라옥 ＰＰＡＲγ에 선택적으로 작용하는 테트라하이드로퀴놀린계열 티아졸리딘디온 유도체 및 그 합성방법
AU2013200104B2 (en) * 2006-03-16 2014-05-15 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic inflammation mediated disease
JP2009530293A (ja) * 2006-03-16 2009-08-27 メタボリック ソリューションズ ディベロップメント カンパニー チアゾリジンジオン類似体およびグルココルチコイドアゴニストの併用療法
CA2646207C (en) * 2006-03-16 2016-01-19 Metabolic Solutions Development Company Thiazolidinedione analogues for the treatment of metabolic inflammation mediated disease
CN101454006B (zh) * 2006-03-16 2012-12-26 新陈代谢解决方案开发公司 用于治疗高血压以及用于降低血脂的噻唑烷二酮类似物
US7435741B2 (en) 2006-05-09 2008-10-14 Teva Pharmaceutical Industries, Ltd. 2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate
WO2008038359A1 (fr) * 2006-09-28 2008-04-03 Daido Kogyo Co., Ltd. Tensionneur de chaîne
US8304441B2 (en) 2007-09-14 2012-11-06 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic diseases
CA2699289C (en) 2007-09-14 2016-01-19 Metabolic Solutions Development Company Thiazolidinedione analogues for the treatment of hypertension
US8722710B2 (en) 2007-09-26 2014-05-13 Deuterx, Llc Deuterium-enriched pioglitazone
US8912335B2 (en) 2009-12-15 2014-12-16 Metabolic Solutions Development Company, Llc PPAR-sparing thiazolidinedione salts for the treatment of metabolic diseases
WO2011133442A1 (en) * 2010-04-19 2011-10-27 Metabolic Solutions Development Company Novel synthesis for thiazolidinedione compounds
CA2796872A1 (en) * 2010-04-19 2011-10-27 Metabolic Solutions Development Company, Llc Novel synthesis for thiazolidinedione compounds
JP5851506B2 (ja) * 2010-08-10 2016-02-03 メタボリック ソリューションズ ディベロップメント カンパニー， エルエルシー チアゾリジンジオン化合物のための合成
EP2603498B1 (en) 2010-08-10 2016-11-09 Octeta Therapeutics, LLC Novel synthesis for thiazolidinedione compounds
US20120094959A1 (en) 2010-10-19 2012-04-19 Bonnie Blazer-Yost Treatment of cystic diseases
AU2014236510A1 (en) * 2013-03-14 2015-09-24 Deuterx, Llc Deuterium-enriched 2,4-thiazolidinediones and methods of treatment
ES2831326T3 (es) 2014-01-15 2021-06-08 Poxel Sa Métodos para tratar trastornos neurológicos, metabólicos y otros mediante el uso de pioglitazona enantiopura enriquecida con deuterio
MX2016012687A (es) 2014-04-02 2017-04-27 Minoryx Therapeutics S L Derivados de 2,4-tiazolidindiona en el tratamiento de trastornos del sistema nervioso central.
US10034868B2 (en) 2014-11-04 2018-07-31 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for the prevention and the treatment of rapidly progressive glomerulonephritis
MX2019006066A (es) 2016-12-01 2019-09-10 Minoryx Therapeutics S L 5-[[4-[2-[5-(1-hidroxietil)piridin-2-il]etoxi]fenil]metil]]-1,3-t iazolidin-2,4-diona para el tratamiento de enfermedad de higado graso no alcoholico.
DK3559010T3 (da) * 2016-12-23 2022-08-15 Minoryx Therapeutics S L Fremgangsmåde til fremstilling af 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedion og salte deraf
US11319313B2 (en) 2020-06-30 2022-05-03 Poxel Sa Crystalline forms of deuterium-enriched pioglitazone
US11767317B1 (en) 2020-06-30 2023-09-26 Poxel Sa Methods of synthesizing enantiopure deuterium-enriched pioglitazone

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
AR240698A1 (es) * 1985-01-19 1990-09-28 Takeda Chemical Industries Ltd Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales

Also Published As

Publication number Publication date
CZ196693A3 (en) 1994-05-18
DE69231886T2 (de) 2002-03-28
FI934426A0 (fi) 1993-10-08
EP0579733A1 (en) 1994-01-26
ES2161692T3 (es) 2001-12-16
NO933615L (no) 1993-10-08
GR3036623T3 (en) 2001-12-31
CA2106967C (en) 2003-12-09
CA2106967A1 (en) 1992-10-12
JP3176694B2 (ja) 2001-06-18
JPH0586057A (ja) 1993-04-06
TW209864B (no) 1993-07-21
MX9201637A (es) 1993-08-01
DK0579733T3 (da) 2001-10-15
AU1743292A (en) 1992-11-17
ATE202352T1 (de) 2001-07-15
KR100249988B1 (ko) 2000-04-01
NO933615D0 (no) 1993-10-08
EP0579733B1 (en) 2001-06-20
HUT68370A (en) 1995-06-28
FI934426A (fi) 1993-10-08
PT100366A (pt) 1993-06-30
DE69231886D1 (de) 2001-07-26
WO1992018501A1 (en) 1992-10-29

Similar Documents

Publication Publication Date Title
SK109993A3 (en) Thiazolidinedione derivatives producing and use thereof
US5441971A (en) Thiazolidinedione derivatives, production and use thereof
US4725610A (en) Thiazolidinedione derivatives, their production and use
US4775687A (en) Thiazolidine derivatives, their production and use
US5965589A (en) Thiazolidinedione derivatives, their production and use
JP2006516137A (ja) Ｃｂ−１リガンドとしての４，５−ジアリールチアゾール誘導体
HU195210B (en) Process for producing pyridine derivatives and pharmaceutical preparations comprising these compounds as active substance
HU196795B (en) Process for producing new thiazolidindione derivatives
PT605228E (pt) Derivados tiazolidinadionas sua preparacao e sua utilizacao
EP0508740B1 (en) Thiazolidinedione derivatives, their production and their use
DE69432542T2 (de) Tetraderivate, ihre Herstellung und Verwendung
EP0748317A1 (en) Novel thiazolidin-4-one derivatives
FR2519986A1 (fr) Nouveaux derives de benzodioxine, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
JPS60208980A (ja) チアゾリジンジオン誘導体、その製造法およびそれを含んでなる糖尿病または高脂血症治療剤
WO1986002073A1 (en) Thiazolidinedione derivatives, process for their preparation, and pharmaceutical composition containing same
JP3466273B2 (ja) テトラゾール誘導体、その製造法およびそれを含んでなる医薬
JPH07309852A (ja) 新規チアゾリジンジオン化合物
JP3836521B2 (ja) ２，４−チアゾリジンジオン誘導体、その製造法およびそれを含んでなる医薬組成物
JPS5939877A (ja) 新規なピリミドン誘導体及びその製造方法
JPH0576468B2 (no)
WO1990011278A1 (en) Thiazole compounds and applications thereof