SI9300349A - Substitunirani piridinil-2 propeonati in njihovi homologi - Google Patents

Substitunirani piridinil-2 propeonati in njihovi homologi Download PDF

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Publication number
SI9300349A
SI9300349A SI9300349A SI9300349A SI9300349A SI 9300349 A SI9300349 A SI 9300349A SI 9300349 A SI9300349 A SI 9300349A SI 9300349 A SI9300349 A SI 9300349A SI 9300349 A SI9300349 A SI 9300349A
Authority
SI
Slovenia
Prior art keywords
methyl
pyridinyl
dichlorophenylthio
sodium
propenoate
Prior art date
Application number
SI9300349A
Other languages
English (en)
Slovenian (sl)
Inventor
Robert A Daines
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of SI9300349A publication Critical patent/SI9300349A/sl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI9300349A 1992-06-30 1993-06-30 Substitunirani piridinil-2 propeonati in njihovi homologi SI9300349A (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90677192A 1992-06-30 1992-06-30
US2519893A 1993-03-02 1993-03-02

Publications (1)

Publication Number Publication Date
SI9300349A true SI9300349A (sl) 1993-12-31

Family

ID=26699422

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9300349A SI9300349A (sl) 1992-06-30 1993-06-30 Substitunirani piridinil-2 propeonati in njihovi homologi

Country Status (16)

Country Link
US (1) US5990314A (ko)
EP (1) EP0649412B1 (ko)
JP (1) JP3230682B2 (ko)
KR (1) KR950702185A (ko)
CN (1) CN1108247A (ko)
AT (1) ATE231129T1 (ko)
AU (2) AU4545893A (ko)
CA (1) CA2138954A1 (ko)
DE (1) DE69332640T2 (ko)
ES (1) ES2191014T3 (ko)
IL (1) IL106156A0 (ko)
MA (1) MA22926A1 (ko)
MX (1) MX9303973A (ko)
NZ (1) NZ253967A (ko)
SI (1) SI9300349A (ko)
WO (1) WO1994000437A1 (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0711282B1 (en) 1993-07-28 2002-06-05 Aventis Pharma Limited Compounds as pde iv and tnf inhibitors
EP0733044A4 (en) * 1993-12-08 1997-03-05 Smithkline Beecham Corp CHEMICAL COMPOUNDS
JPH09506366A (ja) * 1993-12-09 1997-06-24 スミスクライン・ビーチャム・コーポレイション ロイコトリエンb▲下4▼に関連する疾患を治療するのに有用なジフェニル−2−プロペノエートおよびその同族体
DE69609820T2 (de) * 1995-03-02 2001-03-08 Smithkline Beecham Corp Verwendung von substituirten Pyridinverbindungen zur Behandlung der atopischen Dermatitis und der Kontaktdermatitis
GB9508137D0 (en) * 1995-04-21 1995-06-07 Smithkline Beecham Plc Formulation
GB9602675D0 (en) * 1996-02-09 1996-04-10 Smithkline Beecham Plc Process
US5929096A (en) * 1996-02-29 1999-07-27 Smithkline Beecham Corporation Method for treating atopic dermatitis and contact dermatitis
JP2001501202A (ja) * 1996-09-26 2001-01-30 ノバルティス アクチエンゲゼルシャフト ロイコトリエンb4(ltb―4)レセプターアンタゴニスト活性によるアリル置換アクリルアミド
US7361671B2 (en) * 2001-11-15 2008-04-22 The Institute For Pharmaceutical Discovery, Inc. Substituted heteroarylalkanoic acids

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07116150B2 (ja) * 1990-06-07 1995-12-13 スミスクライン・ビーチャム・コーポレイション 安息香酸誘導体
KR930700445A (ko) * 1990-06-07 1993-03-15 원본미기재 로이코트리엔-관련 질병치료용 벤조산 유도체
US5643914A (en) * 1993-03-02 1997-07-01 Smithkline Beecham Corporation Pharmaceutical pyridine compounds

Also Published As

Publication number Publication date
US5990314A (en) 1999-11-23
NZ253967A (en) 1996-11-26
AU4545893A (en) 1994-01-24
AU707102B2 (en) 1999-07-01
CN1108247A (zh) 1995-09-13
DE69332640T2 (de) 2003-11-06
KR950702185A (ko) 1995-06-19
AU2280797A (en) 1997-08-14
ES2191014T3 (es) 2003-09-01
EP0649412B1 (en) 2003-01-15
CA2138954A1 (en) 1994-01-06
EP0649412A1 (en) 1995-04-26
IL106156A0 (en) 1993-10-20
MX9303973A (es) 1994-04-29
JP3230682B2 (ja) 2001-11-19
WO1994000437A1 (en) 1994-01-06
ATE231129T1 (de) 2003-02-15
MA22926A1 (fr) 1994-04-01
JPH07508284A (ja) 1995-09-14
DE69332640D1 (de) 2003-02-20
EP0649412A4 (en) 1995-07-05

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