ES2191014T3 - Compuestos farmaceuticos de piridina. - Google Patents

Compuestos farmaceuticos de piridina.

Info

Publication number
ES2191014T3
ES2191014T3 ES93915498T ES93915498T ES2191014T3 ES 2191014 T3 ES2191014 T3 ES 2191014T3 ES 93915498 T ES93915498 T ES 93915498T ES 93915498 T ES93915498 T ES 93915498T ES 2191014 T3 ES2191014 T3 ES 2191014T3
Authority
ES
Spain
Prior art keywords
piridine
pharmaceutical compounds
pct
sec
date jun
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93915498T
Other languages
English (en)
Inventor
Robert A Daines
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Application granted granted Critical
Publication of ES2191014T3 publication Critical patent/ES2191014T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA INVENCION SE REFIERE A UN COMPUESTO DE FORMULA (I), DONDE SE DEFINEN VARIOS GRUPOS. ESTOS COMPUESTOS SON ANTAGONISTAS DE LEUCOTRIENO, Y COMO TALES PUEDEN USARSE EN EL TRATAMIENTO DE VARIOS ENFERMEDADES RELACIONADAS CON LEUCOTRIENES.
ES93915498T 1992-06-30 1993-06-30 Compuestos farmaceuticos de piridina. Expired - Lifetime ES2191014T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90677192A 1992-06-30 1992-06-30
US2519893A 1993-03-02 1993-03-02

Publications (1)

Publication Number Publication Date
ES2191014T3 true ES2191014T3 (es) 2003-09-01

Family

ID=26699422

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93915498T Expired - Lifetime ES2191014T3 (es) 1992-06-30 1993-06-30 Compuestos farmaceuticos de piridina.

Country Status (16)

Country Link
US (1) US5990314A (es)
EP (1) EP0649412B1 (es)
JP (1) JP3230682B2 (es)
KR (1) KR950702185A (es)
CN (1) CN1108247A (es)
AT (1) ATE231129T1 (es)
AU (2) AU4545893A (es)
CA (1) CA2138954A1 (es)
DE (1) DE69332640T2 (es)
ES (1) ES2191014T3 (es)
IL (1) IL106156A0 (es)
MA (1) MA22926A1 (es)
MX (1) MX9303973A (es)
NZ (1) NZ253967A (es)
SI (1) SI9300349A (es)
WO (1) WO1994000437A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995015950A1 (en) * 1993-12-08 1995-06-15 Smithkline Beecham Corporation Compounds
ZA945609B (en) 1993-07-28 1995-05-12 Rhone Poulenc Rorer Ltd [Di(ether or thioether)heteroaryl or fluoro substituted aryl] compounds
CA2178634A1 (en) * 1993-12-09 1995-06-15 Robert A. Daines Diphenyl-2-propenoates and homologs thereof useful for treating diseases associated with leukotriene b4
JPH11501038A (ja) * 1995-03-02 1999-01-26 スミスクライン・ビーチャム・コーポレイション アトピー性皮膚炎および接触性皮膚炎の治療方法
GB9508137D0 (en) * 1995-04-21 1995-06-07 Smithkline Beecham Plc Formulation
GB9602675D0 (en) * 1996-02-09 1996-04-10 Smithkline Beecham Plc Process
US5929096A (en) * 1996-02-29 1999-07-27 Smithkline Beecham Corporation Method for treating atopic dermatitis and contact dermatitis
WO1998013347A1 (en) * 1996-09-26 1998-04-02 Novartis Ag Aryl-substituted acrylamides with leukotriene b4 (ltb-4) receptor antagonist activity
US7361671B2 (en) * 2001-11-15 2008-04-22 The Institute For Pharmaceutical Discovery, Inc. Substituted heteroarylalkanoic acids

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0532550A1 (en) * 1990-06-07 1993-03-24 Smithkline Beecham Corporation Benzoic acid derivatives for treating leukotriene-related diseases
JPH07116150B2 (ja) * 1990-06-07 1995-12-13 スミスクライン・ビーチャム・コーポレイション 安息香酸誘導体
US5643914A (en) * 1993-03-02 1997-07-01 Smithkline Beecham Corporation Pharmaceutical pyridine compounds

Also Published As

Publication number Publication date
EP0649412B1 (en) 2003-01-15
JP3230682B2 (ja) 2001-11-19
CA2138954A1 (en) 1994-01-06
AU4545893A (en) 1994-01-24
AU2280797A (en) 1997-08-14
ATE231129T1 (de) 2003-02-15
KR950702185A (ko) 1995-06-19
WO1994000437A1 (en) 1994-01-06
DE69332640T2 (de) 2003-11-06
SI9300349A (sl) 1993-12-31
MX9303973A (es) 1994-04-29
NZ253967A (en) 1996-11-26
JPH07508284A (ja) 1995-09-14
MA22926A1 (fr) 1994-04-01
CN1108247A (zh) 1995-09-13
EP0649412A1 (en) 1995-04-26
AU707102B2 (en) 1999-07-01
US5990314A (en) 1999-11-23
IL106156A0 (en) 1993-10-20
EP0649412A4 (en) 1995-07-05
DE69332640D1 (de) 2003-02-20

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