DE69606777T2 - Naphthamidderivate von 3-beta-amino azabicyclooctan oder nonan als antipsychotische arzneimittel - Google Patents

Naphthamidderivate von 3-beta-amino azabicyclooctan oder nonan als antipsychotische arzneimittel

Info

Publication number
DE69606777T2
DE69606777T2 DE69606777T DE69606777T DE69606777T2 DE 69606777 T2 DE69606777 T2 DE 69606777T2 DE 69606777 T DE69606777 T DE 69606777T DE 69606777 T DE69606777 T DE 69606777T DE 69606777 T2 DE69606777 T2 DE 69606777T2
Authority
DE
Germany
Prior art keywords
antipesychotic
azabicyclooctan
nonan
beta
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69606777T
Other languages
English (en)
Other versions
DE69606777D1 (de
Inventor
Thierry Imbert
Barbara Monse
Wouter Koek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Publication of DE69606777D1 publication Critical patent/DE69606777D1/de
Application granted granted Critical
Publication of DE69606777T2 publication Critical patent/DE69606777T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69606777T 1995-09-12 1996-09-11 Naphthamidderivate von 3-beta-amino azabicyclooctan oder nonan als antipsychotische arzneimittel Expired - Fee Related DE69606777T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9510655A FR2738569B1 (fr) 1995-09-12 1995-09-12 Nouveaux derives naphtamide de 3 beta-amino azabicyclo octane ou nonane, leur procede de preparation, leur utilisation a titre de medicament antipsychotique
PCT/FR1996/001394 WO1997010244A1 (fr) 1995-09-12 1996-09-11 DERIVES NAPHTAMIDE DE 3 β-AMINO AZABICYCLO OCTANE OU NONANE, COMME AGENTS ANTIPSYCHOTIQUES

Publications (2)

Publication Number Publication Date
DE69606777D1 DE69606777D1 (de) 2000-03-30
DE69606777T2 true DE69606777T2 (de) 2000-10-12

Family

ID=9482457

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69606777T Expired - Fee Related DE69606777T2 (de) 1995-09-12 1996-09-11 Naphthamidderivate von 3-beta-amino azabicyclooctan oder nonan als antipsychotische arzneimittel

Country Status (17)

Country Link
US (1) US5958945A (de)
EP (1) EP0861252B1 (de)
JP (1) JPH11512418A (de)
KR (1) KR19990044563A (de)
CN (1) CN1060773C (de)
AT (1) ATE189894T1 (de)
AU (1) AU707861B2 (de)
BR (1) BR9610175A (de)
CA (1) CA2232082A1 (de)
DE (1) DE69606777T2 (de)
ES (1) ES2143224T3 (de)
FR (1) FR2738569B1 (de)
GR (1) GR3033358T3 (de)
MX (1) MX9801938A (de)
NZ (1) NZ318434A (de)
PT (1) PT861252E (de)
WO (1) WO1997010244A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100287366B1 (ko) * 1997-11-24 2001-04-16 윤순조 엠피이지 방식을 이용한 휴대용 음향 재생장치 및 방법
FR2831884B1 (fr) * 2001-11-02 2003-12-26 Pf Medicament Nouveaux derives amides heteroaromatiques de 3 beta-amino azabicyclooctane, leur procede de preparation et leurs applications en therapeutique
US7868017B2 (en) * 2005-09-30 2011-01-11 N.V. Organon 9-azabicyclo[3.3.1]nonane derivatives
TW200745101A (en) 2005-09-30 2007-12-16 Organon Nv 9-Azabicyclo[3.3.1]nonane derivatives
US7605170B2 (en) * 2005-12-01 2009-10-20 N.V. Organon 8-azabicyclo[3.2.1]octane derivatives
WO2008083124A1 (en) * 2006-12-28 2008-07-10 Rigel Pharmaceuticals, Inc. N-substituted-heterocycloalkyloxybenzamide compounds and methods of use
KR101578792B1 (ko) 2007-10-25 2015-12-21 엑셀리시스, 인코포레이티드 트로판 화합물
US8441361B2 (en) * 2010-02-13 2013-05-14 Mcallister Technologies, Llc Methods and apparatuses for detection of properties of fluid conveyance systems

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2111479A (en) * 1981-10-01 1983-07-06 Beecham Group Plc Benzamides
FR2682953B1 (fr) * 1991-10-23 1995-04-21 Inst Nat Sante Rech Med Nouveaux derives de naphtamides, leur procede de preparation et leur application dans le domaine therapeutique.
GB9218113D0 (en) * 1992-08-26 1992-10-14 Lilly Industries Ltd Pharmaceutical compounds
US5395835A (en) * 1994-03-24 1995-03-07 Warner-Lambert Company Naphthalamides as central nervous system agents

Also Published As

Publication number Publication date
US5958945A (en) 1999-09-28
BR9610175A (pt) 1998-08-11
CN1060773C (zh) 2001-01-17
NZ318434A (en) 1998-09-24
WO1997010244A1 (fr) 1997-03-20
DE69606777D1 (de) 2000-03-30
FR2738569A1 (fr) 1997-03-14
CA2232082A1 (fr) 1997-03-20
KR19990044563A (ko) 1999-06-25
PT861252E (pt) 2000-08-31
JPH11512418A (ja) 1999-10-26
AU707861B2 (en) 1999-07-22
CN1199399A (zh) 1998-11-18
MX9801938A (es) 1998-10-31
EP0861252B1 (de) 2000-02-23
ES2143224T3 (es) 2000-05-01
ATE189894T1 (de) 2000-03-15
AU6991696A (en) 1997-04-01
FR2738569B1 (fr) 1997-11-28
GR3033358T3 (en) 2000-09-29
EP0861252A1 (de) 1998-09-02

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Legal Events

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8339 Ceased/non-payment of the annual fee