SI3708178T1 - Peptid za uporabo pri preprečevanju ali zdravljenju degeneracije makule - Google Patents

Peptid za uporabo pri preprečevanju ali zdravljenju degeneracije makule

Info

Publication number
SI3708178T1
SI3708178T1 SI201032136T SI201032136T SI3708178T1 SI 3708178 T1 SI3708178 T1 SI 3708178T1 SI 201032136 T SI201032136 T SI 201032136T SI 201032136 T SI201032136 T SI 201032136T SI 3708178 T1 SI3708178 T1 SI 3708178T1
Authority
SI
Slovenia
Prior art keywords
peptide
prevention
treatment
macular degeneration
macular
Prior art date
Application number
SI201032136T
Other languages
English (en)
Slovenian (sl)
Inventor
Shibo Tang
Liping Liu
Xiaoling Liang
Original Assignee
Stealth Biotherapeutics Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stealth Biotherapeutics Inc. filed Critical Stealth Biotherapeutics Inc.
Publication of SI3708178T1 publication Critical patent/SI3708178T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0815Tripeptides with the first amino acid being basic
    • C07K5/0817Tripeptides with the first amino acid being basic the first amino acid being Arg
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1016Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI201032136T 2009-08-24 2010-08-23 Peptid za uporabo pri preprečevanju ali zdravljenju degeneracije makule SI3708178T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US23644009P 2009-08-24 2009-08-24
US23774509P 2009-08-28 2009-08-28
US34847010P 2010-05-26 2010-05-26
EP20156769.0A EP3708178B1 (en) 2009-08-24 2010-08-23 Peptide for use in preventing or treating macular degeneration

Publications (1)

Publication Number Publication Date
SI3708178T1 true SI3708178T1 (sl) 2024-01-31

Family

ID=43628336

Family Applications (2)

Application Number Title Priority Date Filing Date
SI201032136T SI3708178T1 (sl) 2009-08-24 2010-08-23 Peptid za uporabo pri preprečevanju ali zdravljenju degeneracije makule
SI201030612T SI2470191T1 (sl) 2009-08-24 2010-08-23 Postopki in sestavki za prepreäśevanje ali zdravljenje oftalmoloĺ kih stanj

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI201030612T SI2470191T1 (sl) 2009-08-24 2010-08-23 Postopki in sestavki za prepreäśevanje ali zdravljenje oftalmoloĺ kih stanj

Country Status (17)

Country Link
US (8) US8470784B2 (enrdf_load_stackoverflow)
EP (18) EP3292868A1 (enrdf_load_stackoverflow)
JP (7) JP6120399B2 (enrdf_load_stackoverflow)
CN (3) CN105056206A (enrdf_load_stackoverflow)
CA (1) CA2772094C (enrdf_load_stackoverflow)
DK (2) DK2470191T3 (enrdf_load_stackoverflow)
ES (2) ES2487633T3 (enrdf_load_stackoverflow)
FI (1) FI3708178T3 (enrdf_load_stackoverflow)
HK (4) HK1204958A1 (enrdf_load_stackoverflow)
HR (1) HRP20231277T1 (enrdf_load_stackoverflow)
HU (1) HUE064800T2 (enrdf_load_stackoverflow)
LT (1) LT3708178T (enrdf_load_stackoverflow)
PL (2) PL3708178T3 (enrdf_load_stackoverflow)
PT (2) PT2470191E (enrdf_load_stackoverflow)
SI (2) SI3708178T1 (enrdf_load_stackoverflow)
SM (1) SMT202300433T1 (enrdf_load_stackoverflow)
WO (1) WO2011025734A1 (enrdf_load_stackoverflow)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009295960A1 (en) 2008-09-29 2010-04-01 Cardiaq Valve Technologies, Inc. Heart valve
WO2010040009A1 (en) 2008-10-01 2010-04-08 Cardiaq Valve Technologies, Inc. Delivery system for vascular implant
EP2810620B1 (en) 2009-04-15 2022-09-14 Edwards Lifesciences CardiAQ LLC Vascular implant and delivery system
SMT202300433T1 (it) * 2009-08-24 2024-01-10 Stealth Biotherapeutics Inc Peptide per l'uso nella prevenzione o nel trattamento della degenerazione maculare
EP3210615A1 (en) 2010-03-15 2017-08-30 Stealth Peptides International, Inc. Combination therapies using cyclosporine and aromatic cationic peptides
US20110269807A1 (en) * 2010-04-30 2011-11-03 Allergan, Inc. Novel treatment for age related macular degeneration and ocular ischemic disease associated with complement activation by targeting 5-lipoxygenase
US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
WO2012021107A2 (en) 2010-08-12 2012-02-16 Nanyang Technological University A liposomal formulation for ocular drug delivery
JP6010036B2 (ja) 2010-10-01 2016-10-19 ゼット124Z124 タッチセンサ式ディスプレイに画像を表示する方法及び通信デバイスならびにコンピュータ可読媒体
WO2012129427A2 (en) * 2011-03-24 2012-09-27 Cornell University Aromatic-cationic peptides and uses of same
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US9308087B2 (en) 2011-04-28 2016-04-12 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
CN102327600A (zh) * 2011-09-14 2012-01-25 中国人民解放军军事医学科学院放射与辐射医学研究所 用于预防和治疗辐射损伤的rx31肽
US20130076654A1 (en) 2011-09-27 2013-03-28 Imerj LLC Handset states and state diagrams: open, closed transitional and easel
CN104105499A (zh) * 2011-12-09 2014-10-15 康肽德生物医药技术有限公司 芳香族阳离子肽及其用途
EP3281634A1 (en) * 2012-02-22 2018-02-14 Stealth Peptides International, Inc. Method and compositions for preventing or treating ophthalmic conditions
DK2830644T3 (en) * 2012-03-30 2017-02-27 Stealth Peptides Int Inc Methods and Preparations for the Prevention and Treatment of Neuropathy
US9345573B2 (en) 2012-05-30 2016-05-24 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
AU2013296493B2 (en) 2012-08-02 2018-04-26 Stealth Biotherapeutics Inc. Methods for treatment of atherosclerosis
CA2888899C (en) 2012-10-24 2023-02-21 Japan Innovative Therapeutics, Inc. Use of tryptase inhibitors in the treatment retinopathy of prematurity
US9265458B2 (en) 2012-12-04 2016-02-23 Sync-Think, Inc. Application of smooth pursuit cognitive testing paradigms to clinical drug development
ES2750258T3 (es) 2013-03-01 2020-03-25 Stealth Biotherapeutics Corp Métodos y composiciones para la prevención o tratamiento del síndrome de Barth
EP3673913A1 (en) * 2013-03-01 2020-07-01 Stealth Biotherapeutics Corp Methods for the treatment of mitochondrial disease
US10583002B2 (en) 2013-03-11 2020-03-10 Neovasc Tiara Inc. Prosthetic valve with anti-pivoting mechanism
US9380976B2 (en) 2013-03-11 2016-07-05 Sync-Think, Inc. Optical neuroinformatics
US9681951B2 (en) 2013-03-14 2017-06-20 Edwards Lifesciences Cardiaq Llc Prosthesis with outer skirt and anchors
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
WO2014209905A2 (en) 2013-06-26 2014-12-31 Stealth Peptides International, Inc. Methods and compositions for detecting and diagnosing diseases and conditions
WO2015017781A1 (en) * 2013-08-01 2015-02-05 Stealth Peptides International, Inc. Methods and compositions for preventing or treating leber's hereditary optic neuropathy
CA2920735A1 (en) * 2013-08-12 2015-02-19 Stealth Biotherapeutics Corp Combination therapy for the treatment of ischemia-reperfusion injury
CA2928702A1 (en) * 2013-10-25 2015-04-30 Children's Medical Center Corporation Methods of treating or preventing vascular diseases of the retina
US9943563B2 (en) * 2013-12-02 2018-04-17 Stealth Biotherapeutics Corp Compositions and methods for treating vitiligo
US20160317606A1 (en) * 2014-01-06 2016-11-03 Stealth Bio Therapeutics Corp Methods and compositions for preventing or treating dominant optic atrophy
US9956195B2 (en) 2014-01-07 2018-05-01 Nanyang Technological University Stable liposomal formulations for ocular drug delivery
AU2015243261B2 (en) 2014-04-10 2020-06-25 Lankenau Institute For Medical Research Methods and compositions for the treatment of ocular diseases and disorders
EP3502132A1 (en) * 2014-05-28 2019-06-26 Stealth BioTherapeutics Corp Therapeutic compositions including therapeutic small molecules and uses thereof
ES2874562T3 (es) * 2014-12-19 2021-11-05 Kemin Ind Inc Suministro intraocular de moléculas bioactivas mediante el uso de iontoforesis
CN108697772B (zh) 2015-12-30 2022-06-24 马歇尔大学科研协会 用于治疗视网膜病的组合物和方法
CN109476700A (zh) 2016-03-11 2019-03-15 隐形生物治疗公司 结晶盐形式
WO2017177262A1 (en) 2016-04-11 2017-10-19 University Of Canberra Ophthalmic compositions comprising levodopa, an antioxidant and an aqueous carrier
WO2017180535A1 (en) 2016-04-11 2017-10-19 Carnot, Llc Chiral peptides
WO2018187400A1 (en) 2017-04-05 2018-10-11 Stealth Biotherapeutics Corp. Crystalline salt forms of boc-d-arg-dmt-lys-(boc)-phe-nh2
US20180318319A1 (en) 2017-05-04 2018-11-08 Ocular Science, Inc. Compositions and Methods for Treating Eyes and Methods of Preparation
WO2019097318A1 (en) 2017-11-17 2019-05-23 Cellix Bio Private Limited Compositions and methods for the treatment of eye disorders
US10676506B2 (en) 2018-01-26 2020-06-09 Stealth Biotherapeutics Corp. Crystalline bis- and tris-hydrochloride salt of elamipretide
PL424452A1 (pl) * 2018-01-31 2019-08-12 Forty-Four Pharmaceuticals Spółka Z Ograniczoną Odpowiedzialnością Inhibitory obojętnej endopeptydazy (NEP) i ludzkiej rozpuszczalnej endopeptydazy (hSEP) do profilaktyki i leczenia chorób oczu
US11400070B2 (en) * 2018-05-03 2022-08-02 Alimera Sciences, Inc. Methods of treating retinal diseases
JP2021531272A (ja) * 2018-07-16 2021-11-18 ステルス バイオセラピューティックス コープ 外傷性視神経症の処置のための組成物及び方法
JP7520851B2 (ja) * 2018-09-21 2024-07-23 アウフバウ・メディカル・イノベイションズ・リミテッド 緑内障用の組成物および方法
AU2020206010A1 (en) * 2019-01-12 2021-07-22 Cellix Bio Private Limited Combination of selective alpha-adrenergic receptor agonist or an anticholinergic agent and lipoic acid and uses thereof
JP2020174859A (ja) * 2019-04-17 2020-10-29 学校法人日本医科大学 網膜剥離が生じるリスクが低い網膜変性症(rd)モデルマウスを取得する方法
WO2020214990A1 (en) * 2019-04-17 2020-10-22 Ascidian Therapeutics, Inc. Abca4 cell line and methods of use
US11071724B2 (en) 2019-05-17 2021-07-27 Ocular Science, Inc. Compositions and methods for treating presbyopia
MX2021014555A (es) * 2019-05-28 2022-07-27 Elgan Pharma Ltd Composiciones y métodos de tratamiento de la retinopatía.
CA3173100A1 (en) * 2020-03-25 2021-09-30 John T. G. PENA Processes and agents for glaucoma
EP4268825A4 (en) * 2020-12-24 2024-12-11 Santen Pharmaceutical Co., Ltd. PHARMACEUTICAL COMPOSITION FOR TRANSDERMAL ADMINISTRATION CONTAINING EPINASTIN OR SALT THEREOF WITH SULPHUR-BASED ANTIOXIDANT
JP2024539150A (ja) * 2021-10-20 2024-10-28 ステルス バイオセラピューティクス インコーポレイテッド 眼の状態を治療、予防、阻害、改善、又はその発症を遅延させるためのペプチド模倣物を含む方法及び組成物
WO2023069255A1 (en) * 2021-10-20 2023-04-27 Stealth Biotherapeutics Inc. Methods and compositions comprising peptidomimitics for treating, preventing, inhibiting, ameliorating or delaying the onset of ophthalmic conditions
WO2023086873A1 (en) * 2021-11-10 2023-05-19 Reverspah Llc Methods and compositions for treating cancer
CN114099678A (zh) * 2021-11-23 2022-03-01 浙江大学 基于Keap1-Nrf2信号通路的晶状体损伤抑制剂
KR102662922B1 (ko) * 2022-05-31 2024-05-03 주식회사 세네릭스 신규의 d-아미노산 유도체 및 이를 포함하는 약학 조성물

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US5602100A (en) 1988-06-30 1997-02-11 Astra Ab Dermorphin analogs having pharmacological activity
EP0350221B1 (en) 1988-06-30 1996-04-17 Astra Aktiebolag Dermorphin analogs, their methods of preparation, pharmaceutical compositions, and methods of therapeutic treatment using the same
US5674980A (en) 1989-12-21 1997-10-07 Biogen Inc Fusion protein comprising tat-derived transport moiety
US5858784A (en) 1991-12-17 1999-01-12 The Regents Of The University Of California Expression of cloned genes in the lung by aerosol- and liposome-based delivery
US5674534A (en) 1992-06-11 1997-10-07 Alkermes, Inc. Composition for sustained release of non-aggregated erythropoietin
US5716644A (en) 1992-06-11 1998-02-10 Alkermes, Inc. Composition for sustained release of non-aggregated erythropoietin
ATE255450T1 (de) 1995-06-09 2003-12-15 Hisamitsu Pharmaceutical Co Matrix für iontophorese
US5849761A (en) 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
US5885958A (en) 1997-03-25 1999-03-23 Administrators Of The Tulane Educational Fund Mu-opiate receptor peptides
US5989463A (en) 1997-09-24 1999-11-23 Alkermes Controlled Therapeutics, Inc. Methods for fabricating polymer-based controlled release devices
CA2314267A1 (en) 1997-12-10 1999-06-17 Washington University Anti-pathogen system and methods of use thereof
AU3965699A (en) 1998-04-24 1999-11-16 Mitokor Compounds and methods for treating mitochondria-associated diseases
US6245740B1 (en) 1998-12-23 2001-06-12 Amgen Inc. Polyol:oil suspensions for the sustained release of proteins
SE9900961D0 (sv) 1999-03-16 1999-03-16 Astra Ab Novel compounds
DE60042338D1 (de) 1999-10-04 2009-07-16 Univ New Jersey Med TAR RNA bindende Peptide
US6759520B1 (en) 1999-10-28 2004-07-06 The New England Medical Center Hospitals, Inc. Chimeric analgesic peptides
US20050192215A1 (en) 2000-01-21 2005-09-01 Malabika Ghosh Methods and materials relating to novel polypeptides and polynucleotides
JP2001270832A (ja) * 2000-03-27 2001-10-02 Ito En Ltd 網膜障害予防剤
AU2001277908A1 (en) 2000-07-18 2002-01-30 Cornell Research Foundation Inc. Medicinal uses of mu-opioid receptor agonists
US6900178B2 (en) 2000-09-12 2005-05-31 University Of Kentucky Research Foundation Protection against ischemia and reperfusion injury
US20070015146A1 (en) 2001-05-22 2007-01-18 Gene Logic, Inc. Molecular nephrotoxicology modeling
WO2004016214A2 (en) * 2002-08-14 2004-02-26 Medical College Of Georgia Research Institute, Inc. Methods and compositions for treatment of macular and retinal disease
US7354574B2 (en) * 2002-11-07 2008-04-08 Advanced Ocular Systems Limited Treatment of ocular disease
US20060172972A1 (en) 2002-12-20 2006-08-03 Chakshu Research Inc Formulation and method for administration of ophthalmologically active agents
JP4838114B2 (ja) 2003-02-04 2011-12-14 コーネル リサーチ ファウンデイション インコーポレイテッド ミトコンドリア透過性転移の阻止方法
JP2004323486A (ja) * 2003-04-30 2004-11-18 National Institute Of Advanced Industrial & Technology 網膜及び/又はブドウ膜疾患の予防乃至治療用点眼薬
DK2604286T3 (en) 2003-05-01 2014-12-08 Cornell Res Foundation Inc Method and carrier complex for delivering molecules to cells
WO2005032481A2 (en) 2003-09-30 2005-04-14 Scios Inc. Quinazoline derivatives as medicaments
CA2554166C (en) * 2004-01-23 2014-07-29 Cornell Research Foundation, Inc. Methods for reducing oxidative damage
WO2005099715A2 (en) 2004-04-08 2005-10-27 Retmed Pty Ltd. Treatment of ophthalmic conditions with mineralcorticoids
US20050272101A1 (en) 2004-06-07 2005-12-08 Prasad Devarajan Method for the early detection of renal injury
JP4760111B2 (ja) 2005-04-26 2011-08-31 株式会社セガ 映像オブジェクト表現用データ構造生成プログラム、映像オブジェクト表現用データ構造生成方法、映像ソフト開発装置、映像処理プログラム、映像処理方法、映像処理装置、映像オブジェクト表現用データ構造、および、記録媒体
US8088773B2 (en) 2005-05-12 2012-01-03 The Texas A&M University System Therapeutic compositions and methods
JP2007043629A (ja) * 2005-06-30 2007-02-15 Sony Corp グラフィック・ユーザ・インタフェース装置と操作入力処理方法及び双方向コミュニケーション装置
CA2615360A1 (en) 2005-07-15 2007-01-25 Chakshu Research Inc. Formulation and method for administration of ophthalmologically active agents
CA2947335A1 (en) * 2005-09-16 2007-03-29 Cornell Research Foundation, Inc. Methods for reducing cd36 expression
CA2623563A1 (en) 2005-10-05 2007-04-19 Aqumen Biopharmaceuticals K.K. Method of inhibiting angiogenesis by using ephrin b2
US20070259377A1 (en) 2005-10-11 2007-11-08 Mickey Urdea Diabetes-associated markers and methods of use thereof
TW200744627A (en) 2006-02-21 2007-12-16 Pfizer Prod Inc Methods for the treatment of macular degeneration and related eye conditions
KR20110079922A (ko) * 2006-04-14 2011-07-11 노파르티스 아게 안과 장애 치료를 위한 il-1 항체의 용도
US20080027082A1 (en) 2006-06-19 2008-01-31 Berthold Hocher Use of adenosine a1 antagonists in radiocontrast media induced nephropathy
DE102006042329B4 (de) * 2006-09-01 2008-08-21 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zum selektiven plasmachemischen Trockenätzen von auf Oberflächen von Silicium-Wafern ausgebildetem Phosphorsilikatglas
BRPI0720038A2 (pt) 2006-12-11 2013-12-24 Univ Utah Res Found Métodos para inibir a permeabilidade vascular em tecido, para triar ou avaliar um agente que inibe a permeabilidade vascular, para tratar ou prevenir a síndrome da angústia respiratória, a retinopatia de prematuridade, a retinopatia diabética e a degeneração macular úmida em um indivíduo, para tratar indivíduos com sugestões repulsivas ou miméticos e para promover a angiogênese em um tecido, polipeptídeo isolado, ácido nucleico isolado, e, vetor
JP2008195655A (ja) * 2007-02-14 2008-08-28 Kitasato Institute 糖尿病白内障の治療剤
JP2008247898A (ja) * 2007-03-08 2008-10-16 Santen Pharmaceut Co Ltd トリテルペノイドを有効成分として含有する酸化ストレスが関連する眼疾患の予防又は治療剤
JP5314931B2 (ja) * 2007-05-25 2013-10-16 参天製薬株式会社 加齢黄斑変性の予防又は治療剤
CN101939019B (zh) * 2008-02-07 2014-07-16 康奈尔大学 用于预防或治疗胰岛素抵抗性的方法
JP5677096B2 (ja) * 2008-02-26 2015-02-25 コーネル ユニヴァーシティー 急性腎障害を予防および治療するための方法
EP3563862B1 (en) 2009-03-20 2021-05-05 The General Hospital Corporation d/b/a Massachusetts General Hospital D-arg-2'6'-dimethyltyrosine-lys-phe-nh2 for use in the prevention of secondary complications of burn injuries
FR2945540B1 (fr) 2009-05-15 2012-06-08 Rhodia Operations Procede de preparation de mousse polyamide et mousse susceptible d'etre obtenue par ce procede
EP3251686A1 (en) 2009-08-12 2017-12-06 Cornell University Methods for preventing or treating metabolic syndrome
SMT202300433T1 (it) * 2009-08-24 2024-01-10 Stealth Biotherapeutics Inc Peptide per l'uso nella prevenzione o nel trattamento della degenerazione maculare
CA3008993A1 (en) * 2010-01-25 2011-07-28 Cornell University Aromatic-cationic peptides and uses of same
EP2538958A4 (en) * 2010-02-26 2013-08-28 Univ Florida ANTIOXIDANTS TAKEN TO MITOCHONDRIA FOR PROTECTION AGAINST MEMBRANE DYSFUNCTION AND SKELETAL MUSCLE ATROPHY INDUCED BY MECHANICAL VENTILATION
EP3290433A1 (en) 2010-05-03 2018-03-07 Stealth Peptides International, Inc. Aromatic-cationic peptides and uses of same
CA2839408A1 (en) 2011-06-14 2012-12-20 Stealth Peptides International, Inc. Aromatic-cationic peptides and uses of same
US10293020B2 (en) * 2013-06-27 2019-05-21 Stealth Biotherapeutics Corp. Peptide therapeutics and methods for using same
US20160199437A1 (en) * 2015-01-08 2016-07-14 D. Travis Wilson Therapeutic compositions including iron chelators and uses thereof
US20160228491A1 (en) * 2015-02-09 2016-08-11 Stealth Biotherapeutics Corp Therapeutic compositions including phenazine-3-one and phenothiazine-3-one derivatives and uses thereof

Also Published As

Publication number Publication date
EP2470191B1 (en) 2014-05-07
PL3708178T3 (pl) 2024-05-13
EP3708178B1 (en) 2023-10-04
EP2470191A1 (en) 2012-07-04
SI2470191T1 (sl) 2014-08-29
EP4302829A2 (en) 2024-01-10
CA2772094A1 (en) 2011-03-03
US9023807B2 (en) 2015-05-05
PT3708178T (pt) 2023-11-16
LT3708178T (lt) 2023-12-27
HK1217900A1 (en) 2017-01-27
HK1206258A1 (en) 2016-01-08
US20160058825A1 (en) 2016-03-03
JP2016026188A (ja) 2016-02-12
EP3494983A1 (en) 2019-06-12
DK2470191T3 (da) 2014-07-07
EP2990049A1 (en) 2016-03-02
US20230346874A1 (en) 2023-11-02
CN102625709A (zh) 2012-08-01
JP2022001609A (ja) 2022-01-06
US11944662B2 (en) 2024-04-02
EP4302829B1 (en) 2025-05-21
JP6332757B2 (ja) 2018-05-30
EP3124036A1 (en) 2017-02-01
HK1204958A1 (en) 2015-12-11
US8470784B2 (en) 2013-06-25
EP3292868A1 (en) 2018-03-14
EP3150215A1 (en) 2017-04-05
EP3708178A1 (en) 2020-09-16
EP4596049A3 (en) 2025-08-13
ES2964555T3 (es) 2024-04-08
US9549963B2 (en) 2017-01-24
EP2470191A4 (en) 2013-04-17
HUE064800T2 (hu) 2024-04-28
JP2017141306A (ja) 2017-08-17
PL2470191T3 (pl) 2014-09-30
HRP20231277T1 (hr) 2024-02-02
US20170326197A1 (en) 2017-11-16
HK1247821A1 (zh) 2018-10-05
PT2470191E (pt) 2014-06-12
WO2011025734A1 (en) 2011-03-03
US11612633B2 (en) 2023-03-28
EP3524256A1 (en) 2019-08-14
EP4302829A3 (en) 2024-03-27
CA2772094C (en) 2018-04-03
JP2018162329A (ja) 2018-10-18
JP6120399B2 (ja) 2017-04-26
EP3318264A1 (en) 2018-05-09
FI3708178T3 (fi) 2023-11-09
EP4596049A2 (en) 2025-08-06
US20210154259A1 (en) 2021-05-27
CN107412722A (zh) 2017-12-01
EP2813235A1 (en) 2014-12-17
HK1172833A1 (en) 2013-05-03
EP2826487A1 (en) 2015-01-21
US20230381264A1 (en) 2023-11-30
US20110177047A1 (en) 2011-07-21
EP3338788A1 (en) 2018-06-27
US20140044689A1 (en) 2014-02-13
SMT202300433T1 (it) 2024-01-10
JP7642965B2 (ja) 2025-03-11
US10188692B2 (en) 2019-01-29
DK3708178T3 (da) 2023-11-13
US20200061147A1 (en) 2020-02-27
EP3485896A1 (en) 2019-05-22
JP2013502460A (ja) 2013-01-24
EP2957291A1 (en) 2015-12-23
EP3175862A1 (en) 2017-06-07
ES2487633T3 (es) 2014-08-22
CN105056206A (zh) 2015-11-18
JP6381737B2 (ja) 2018-08-29
JP2023179733A (ja) 2023-12-19
EP2962695A1 (en) 2016-01-06
JP2020128431A (ja) 2020-08-27

Similar Documents

Publication Publication Date Title
SI3708178T1 (sl) Peptid za uporabo pri preprečevanju ali zdravljenju degeneracije makule
ZA201200239B (en) Derivative of glp-1 analogue or its pharmaceutical salts and their use
AP2015008931A0 (en) Benzothiazole compounds and their pharmaceutical use
AP2925A (en) Inhibitors of human immunodeficiency virus replication
SI2935303T1 (sl) 4'-fluoro-nukleozidi, 4'-fluoro-nukleotidi in njihovi analogi za zdravljenje HCV
BR112012004281A2 (pt) uso de metformina tratamento e prevenção de câncer
IL229353B (en) Dolestatin derivatives related to unnatural amino acids and medicinal preparations that include them
IL231536A (en) Indazole-3-carboxamides, pharmaceuticals containing them and their use in the treatment of diseases
CL2013001891A1 (es) Compuestos heterociclicos fusionados; composicion farmaceutica y uso en el tratamiento de la degeneracion macular asociada con la edad.
DK2774616T3 (da) Anvendelse af roseburia i behandling og forebyggelse af fedmerelaterede sygdomme
PL2512470T3 (pl) Oszczędzające ppar tiazolidynodiony i połączenia do leczenia chorób neurodegeneracyjnych
EP2760460A4 (en) CATIONIC AROMATIC PEPTIDES AND METHODS OF USE
TWI559929B (en) Pharmaceutical composition for use in the treatment of a neurodegenerative disease
PL2726470T3 (pl) Pochodne 1,2,4-tiadiazol-5-ilo piperazyny przydatne w leczeniu chorób neurodegeneracyjnych
IL228436A0 (en) Pyridopyrazine history and their use
ZA201208454B (en) Use of diatomaceous earth in the pharmaceutocal industry
ZA201307058B (en) Use of polyaminoisoprenyl derrivatives in antobiotic or antisertic treatment
GB2515440B (en) Vesicular Formulations for use in the treatment of Rosacea
HRP20181116T1 (hr) Koncentrati za tretiranje supstrata
HRP20180011T1 (hr) Spojevi za uporabu u liječenju filariaza
PL2692345T3 (pl) Kompozycja farmaceutyczna do zapobiegania lub leczenia zwyrodnienia plamki żółtej
HRP20151393T8 (hr) UPORABA BENZIDAMINA U LIJEČENJU BOLESTI KOJE SU p40-OVISNE
HK40103778A (en) Peptide for use in preventing or treating macular degeneration
BRPI1007780A2 (pt) artigos de mascaramento e formulação de tratamento indutor de barreira
AP3019A (en) Use of ferroquine in the treatment or prevention of malaria