SI3096746T1 - Transdermalni sistemi za odvračanje od zlorabe in napačne uporabe - Google Patents

Transdermalni sistemi za odvračanje od zlorabe in napačne uporabe

Info

Publication number
SI3096746T1
SI3096746T1 SI201530710T SI201530710T SI3096746T1 SI 3096746 T1 SI3096746 T1 SI 3096746T1 SI 201530710 T SI201530710 T SI 201530710T SI 201530710 T SI201530710 T SI 201530710T SI 3096746 T1 SI3096746 T1 SI 3096746T1
Authority
SI
Slovenia
Prior art keywords
abuse
transdermal systems
deterrent transdermal
misuse deterrent
misuse
Prior art date
Application number
SI201530710T
Other languages
English (en)
Inventor
David James Enscore
Frank Tagliaferri
Steven Paul Damon
Alan Smith
Jeffrey C. Gaulding
Original Assignee
4P Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 4P Therapeutics filed Critical 4P Therapeutics
Publication of SI3096746T1 publication Critical patent/SI3096746T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive plasters or dressings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F214/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen
    • C08F214/18—Monomers containing fluorine
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F214/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen
    • C08F214/18—Monomers containing fluorine
    • C08F214/26—Tetrafluoroethene
SI201530710T 2014-01-22 2015-01-21 Transdermalni sistemi za odvračanje od zlorabe in napačne uporabe SI3096746T1 (sl)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201461930090P 2014-01-22 2014-01-22
US201461930104P 2014-01-22 2014-01-22
US201462014723P 2014-06-20 2014-06-20
US201462014721P 2014-06-20 2014-06-20
US201462083620P 2014-11-24 2014-11-24
EP15740893.1A EP3096746B1 (en) 2014-01-22 2015-01-21 Abuse and misuse deterrent transdermal systems
PCT/US2015/012196 WO2015112563A2 (en) 2014-01-22 2015-01-21 Abuse and misuse deterrent transdermal systems

Publications (1)

Publication Number Publication Date
SI3096746T1 true SI3096746T1 (sl) 2019-07-31

Family

ID=53682116

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201530710T SI3096746T1 (sl) 2014-01-22 2015-01-21 Transdermalni sistemi za odvračanje od zlorabe in napačne uporabe

Country Status (20)

Country Link
US (5) US20170007550A1 (sl)
EP (1) EP3096746B1 (sl)
JP (1) JP6525165B2 (sl)
KR (1) KR102226652B1 (sl)
CN (3) CN115475048A (sl)
AU (1) AU2015209466B2 (sl)
CA (1) CA2937649C (sl)
CY (1) CY1121654T1 (sl)
DK (1) DK3096746T3 (sl)
ES (1) ES2729871T3 (sl)
HR (1) HRP20191048T1 (sl)
HU (1) HUE044966T2 (sl)
LT (1) LT3096746T (sl)
MX (1) MX369030B (sl)
PL (1) PL3096746T3 (sl)
PT (1) PT3096746T (sl)
RS (1) RS58759B1 (sl)
RU (1) RU2700926C2 (sl)
SI (1) SI3096746T1 (sl)
WO (1) WO2015112563A2 (sl)

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RU2700926C2 (ru) * 2014-01-22 2019-09-24 4П Терапьютикс Трансдермальные системы, предотвращающие злоупотребление и неправильное употребление
CA2974324A1 (en) 2015-01-28 2016-08-04 Zita S. Netzel Drug delivery methods and systems
WO2016145373A1 (en) 2015-03-12 2016-09-15 Chrono Therapeutics Inc. Craving input and support system
US20170273974A1 (en) 2016-03-24 2017-09-28 Medrx Co., Ltd Patch preparations with misuse prevention features
WO2017164084A1 (ja) * 2016-03-24 2017-09-28 株式会社メドレックス 誤用防止特性を有する貼付製剤
AU2018205529B2 (en) 2017-01-06 2023-08-10 Morningside Venture Investments Limited Transdermal drug delivery devices and methods
JP7420797B2 (ja) 2018-05-29 2024-01-23 モーニングサイド ベンチャー インベストメンツ リミテッド 薬剤送達の方法及びシステム
KR20210096592A (ko) * 2018-08-23 2021-08-05 번스타인, 에릭, 에프 피부 질환을 치료하기 위해 항-vegf 화합물을 도포하고 이러한 화합물을 이용하기 위한 시스템, 장치, 및 방법
CN112526037A (zh) * 2020-12-07 2021-03-19 温州市质量技术检测科学研究院 一种检测巴克球中苦精的方法
CN114668748A (zh) * 2022-05-18 2022-06-28 张钊源 渐变型透皮贴剂及其制备方法、药物方面的应用

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KR19990026792A (ko) * 1997-09-26 1999-04-15 김윤 디클로페낙 디에틸암모늄염을 함유한 매트릭스형 패취제제
GB0026137D0 (en) * 2000-10-25 2000-12-13 Euro Celtique Sa Transdermal dosage form
WO2004017941A2 (en) * 2002-08-20 2004-03-04 Euro-Celtique, S.A. Transdermal dosage form comprising an active agent and a salt and free-baseform of an antagonist
US20040109886A1 (en) * 2002-08-27 2004-06-10 Larry Rigby Methods and apparatus for transdermal delivery of abusable drugs with a deterrent agent
AU2004227918B2 (en) * 2003-04-04 2010-01-07 Board Of Regents, The University Of Texas System Polyamine/alkali salt blends for carbon dioxide removal from gas streams
CN1780611B (zh) * 2003-04-30 2013-01-30 珀杜医药公司 包括活性剂部分以及在活性剂层远侧的逆转剂的抗改造透皮剂型
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CN112741822A (zh) * 2019-10-30 2021-05-04 江苏集萃新型药物制剂技术研究所有限公司 一种用于皮肤或粘膜释放活性物质的透皮贴剂给药系统

Also Published As

Publication number Publication date
EP3096746A2 (en) 2016-11-30
RU2016133853A3 (sl) 2018-09-18
ES2729871T3 (es) 2019-11-06
CA2937649A1 (en) 2015-07-30
HUE044966T2 (hu) 2019-11-28
KR102226652B1 (ko) 2021-03-12
US20240000720A1 (en) 2024-01-04
US20200113845A1 (en) 2020-04-16
US20220125739A1 (en) 2022-04-28
JP2017505312A (ja) 2017-02-16
MX369030B (es) 2019-10-25
CN115475048A (zh) 2022-12-16
LT3096746T (lt) 2019-06-10
CA2937649C (en) 2022-11-01
US11759431B2 (en) 2023-09-19
MX2016009493A (es) 2017-05-09
US11246840B2 (en) 2022-02-15
AU2015209466B2 (en) 2019-03-07
CN106459293A (zh) 2017-02-22
US20170007550A1 (en) 2017-01-12
PL3096746T3 (pl) 2019-09-30
RU2700926C2 (ru) 2019-09-24
EP3096746A4 (en) 2017-08-23
US20190076374A1 (en) 2019-03-14
RU2016133853A (ru) 2018-03-02
JP6525165B2 (ja) 2019-06-05
EP3096746B1 (en) 2019-03-13
WO2015112563A2 (en) 2015-07-30
DK3096746T3 (da) 2019-05-20
PT3096746T (pt) 2019-06-17
WO2015112563A3 (en) 2015-11-19
CN115444659A (zh) 2022-12-09
CY1121654T1 (el) 2020-07-31
AU2015209466A1 (en) 2016-08-11
HRP20191048T1 (hr) 2019-09-06
RS58759B1 (sr) 2019-06-28
KR20160108831A (ko) 2016-09-20

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