SI2994528T1 - Organoidi, ki obsegajo izolirane ledvične celice in njihove uporabe - Google Patents

Organoidi, ki obsegajo izolirane ledvične celice in njihove uporabe

Info

Publication number
SI2994528T1
SI2994528T1 SI201432063T SI201432063T SI2994528T1 SI 2994528 T1 SI2994528 T1 SI 2994528T1 SI 201432063 T SI201432063 T SI 201432063T SI 201432063 T SI201432063 T SI 201432063T SI 2994528 T1 SI2994528 T1 SI 2994528T1
Authority
SI
Slovenia
Prior art keywords
organoids
renal cells
isolated renal
isolated
cells
Prior art date
Application number
SI201432063T
Other languages
English (en)
Slovenian (sl)
Inventor
Joydeep Basu
Andrew Bruce
Rusty Kelley
Kelly Guthrie
Original Assignee
Prokidney
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prokidney filed Critical Prokidney
Publication of SI2994528T1 publication Critical patent/SI2994528T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/22—Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0684—Cells of the urinary tract or kidneys
    • C12N5/0686—Kidney cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/25—Urinary tract cells, renal cells
    • C12N2502/256—Renal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/28—Vascular endothelial cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/00—3D culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Vascular Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Materials For Medical Uses (AREA)
SI201432063T 2013-05-08 2014-05-08 Organoidi, ki obsegajo izolirane ledvične celice in njihove uporabe SI2994528T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361855146P 2013-05-08 2013-05-08
US201361855152P 2013-05-09 2013-05-09
PCT/US2014/037275 WO2014182885A2 (en) 2013-05-08 2014-05-08 Organoids comprising isolated renal cells and uses thereof
EP14730323.4A EP2994528B1 (en) 2013-05-08 2014-05-08 Organoids comprising isolated renal cells and uses thereof

Publications (1)

Publication Number Publication Date
SI2994528T1 true SI2994528T1 (sl) 2024-04-30

Family

ID=50942860

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201432063T SI2994528T1 (sl) 2013-05-08 2014-05-08 Organoidi, ki obsegajo izolirane ledvične celice in njihove uporabe

Country Status (17)

Country Link
US (2) US20160101133A1 (https=)
EP (2) EP4299721A3 (https=)
JP (4) JP6490669B2 (https=)
KR (8) KR102710014B1 (https=)
CN (1) CN105378062A (https=)
AU (3) AU2014262670B2 (https=)
CA (1) CA2911291A1 (https=)
DK (1) DK2994528T3 (https=)
ES (1) ES2970230T3 (https=)
FI (1) FI2994528T3 (https=)
HR (1) HRP20240170T1 (https=)
HU (1) HUE065125T2 (https=)
PL (1) PL2994528T3 (https=)
PT (1) PT2994528T (https=)
RU (1) RU2722361C2 (https=)
SI (1) SI2994528T1 (https=)
WO (1) WO2014182885A2 (https=)

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JP6804438B2 (ja) 2014-10-17 2020-12-23 チルドレンズ ホスピタル メディカル センター 多能性幹細胞を使用するヒト小腸のｉｎ ｖｉｖｏモデル、並びにそれを作製、及び使用する方法
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WO2019006127A1 (en) * 2017-06-28 2019-01-03 Rutgers, The State University Of New Jersey ORGANOIDS DERIVED FROM A SINGLE RENAL CELL
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JP2019196342A (ja) * 2018-05-10 2019-11-14 学校法人大阪医科薬科大学 スタチン封入ナノ粒子製剤、それを含有する歯髄由来幹細胞及びそれを含む細胞製剤。
US12320800B2 (en) 2018-05-16 2025-06-03 University Of Washington High-throughput automation of organoids for identifying therapeutic strategies
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KR20200065892A (ko) * 2018-11-30 2020-06-09 오가노이드사이언스 주식회사 오가노이드의 생체 이식용 조성물
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Also Published As

Publication number Publication date
AU2023206151B2 (en) 2026-01-29
EP4299721A3 (en) 2024-04-24
DK2994528T3 (da) 2024-02-05
BR112015027996A8 (pt) 2017-10-10
KR102618557B1 (ko) 2023-12-28
HUE065125T2 (hu) 2024-05-28
EP2994528A2 (en) 2016-03-16
KR20160005037A (ko) 2016-01-13
KR102710014B1 (ko) 2024-09-26
KR102225312B1 (ko) 2021-03-10
WO2014182885A2 (en) 2014-11-13
KR20240144472A (ko) 2024-10-02
JP2019122381A (ja) 2019-07-25
KR20220005636A (ko) 2022-01-13
AU2020203860B2 (en) 2023-04-27
JP7493252B2 (ja) 2024-05-31
AU2014262670A1 (en) 2015-11-26
BR112015027996A2 (pt) 2017-09-12
WO2014182885A3 (en) 2015-04-16
RU2015152257A (ru) 2017-06-09
AU2023206151A1 (en) 2023-08-10
FI2994528T3 (fi) 2024-02-07
JP2022071069A (ja) 2022-05-13
RU2722361C2 (ru) 2020-05-29
KR102668827B1 (ko) 2024-05-27
CA2911291A1 (en) 2014-11-13
JP6490669B2 (ja) 2019-03-27
NZ752702A (en) 2021-11-26
CN105378062A (zh) 2016-03-02
PT2994528T (pt) 2024-02-13
HRP20240170T1 (hr) 2024-04-12
PL2994528T3 (pl) 2024-04-22
JP7062605B2 (ja) 2022-05-06
KR20240001290A (ko) 2024-01-03
EP2994528B1 (en) 2023-11-08
KR20230110834A (ko) 2023-07-25
US20220249569A1 (en) 2022-08-11
NZ713875A (en) 2021-11-26
AU2014262670B2 (en) 2020-07-09
KR20210029285A (ko) 2021-03-15
KR20240090622A (ko) 2024-06-21
AU2020203860A1 (en) 2020-07-02
KR102281921B1 (ko) 2021-07-28
JP2024105523A (ja) 2024-08-06
KR102556951B1 (ko) 2023-07-18
ES2970230T3 (es) 2024-05-27
KR20210094671A (ko) 2021-07-29
KR102349183B1 (ko) 2022-01-07
JP2016519930A (ja) 2016-07-11
EP4299721A2 (en) 2024-01-03
KR102757386B1 (ko) 2025-01-21
US20160101133A1 (en) 2016-04-14

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