SI2533774T1 - Uporaba agomelatina za pripravo zdravil za zdravljenje obsesivno-kompulzivne motnje (okm) - Google Patents

Uporaba agomelatina za pripravo zdravil za zdravljenje obsesivno-kompulzivne motnje (okm) Download PDF

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Publication number
SI2533774T1
SI2533774T1 SI201131444T SI201131444T SI2533774T1 SI 2533774 T1 SI2533774 T1 SI 2533774T1 SI 201131444 T SI201131444 T SI 201131444T SI 201131444 T SI201131444 T SI 201131444T SI 2533774 T1 SI2533774 T1 SI 2533774T1
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SI
Slovenia
Prior art keywords
agomelatine
compulsive disorder
treatment
okm
obsessive
Prior art date
Application number
SI201131444T
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English (en)
Inventor
Laurence Laigle
Elisabeth Mocaer
Mark J. Millan
Original Assignee
Les Laboratoires Servier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Les Laboratoires Servier filed Critical Les Laboratoires Servier
Publication of SI2533774T1 publication Critical patent/SI2533774T1/sl

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Claims (6)

  1. UPORABA AGOMELATINA ZA PRIPRAVO ZDRAVIL ZA ZDRAVLJENJE OBSESIVNO-KOMPULZIVNE MOTNJE (OKM) Patentni zahtevki
    1. Uporaba agomelatina oziroma A/-[2-(7-metoksi-1-naftil)etil]acetamida oziroma enega izmed njegovih hidratov, kristaliničnih oblik in dodatnih soli s farmacevtsko sprejemljivo kislino ali bazo, kot edino aktivno sestavino, za pridobivanje zdravila za zdravljenje obsesivno-kompulzivne motnje (OKM).
  2. 2. Uporaba po zahtevku 1, označena s tem, da se agomelatin pridobi v kristalinični obliki II, kot je opisano v patentni prijavi EP1564202.
  3. 3. Farmacevtski sestavki, ki jih sestavlja agomelatin oziroma eden izmed njegovih hidratov, kristaliničnih oblik in dodatnih soli s farmacevtsko sprejemljivo kislino ali bazo, samostojno ali v kombinaciji z eno ali več farmacevtsko sprejemljivimi pomožnimi snovmi, za uporabo pri zdravljenju obsesivno-kompulzivne motnje (OKM).
  4. 4. Farmacevtski sestavek za uporabo po zahtevku 3, označen s tem, da se agomelatin pridobi v kristalinični obliki II, kot je opisano v patentni prijavi EP1564202.
  5. 5. Agomelatin oziroma A/-[2-(7-metoksi-1-naftil)etil]acetamid oziroma eden izmed njegovih hidratov, kristaliničnih oblik in dodatnih soli s farmacevtsko sprejemljivo kislino ali bazo za uporabo pri zdravljenju obsesivno-kompulzivne motnje (OKM).
  6. 6. Kristalinična oblika II agomelatina, kot je opisana v patentni prijavi EP1564202, za uporabo pri zdravljenju obsesivno-kompulzivne motnje (OKM).
SI201131444T 2010-02-11 2011-02-10 Uporaba agomelatina za pripravo zdravil za zdravljenje obsesivno-kompulzivne motnje (okm) SI2533774T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1000560A FR2956031B1 (fr) 2010-02-11 2010-02-11 Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble obsessionnel compulsif (toc)
EP11708533.2A EP2533774B1 (fr) 2010-02-11 2011-02-10 Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble obsessionnel compulsif (toc)
PCT/FR2011/000080 WO2011098689A2 (fr) 2010-02-11 2011-02-10 Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble obsessionnel compulsif (toc)

Publications (1)

Publication Number Publication Date
SI2533774T1 true SI2533774T1 (sl) 2018-05-31

Family

ID=42244669

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201131444T SI2533774T1 (sl) 2010-02-11 2011-02-10 Uporaba agomelatina za pripravo zdravil za zdravljenje obsesivno-kompulzivne motnje (okm)

Country Status (34)

Country Link
US (1) US20120309838A1 (sl)
EP (1) EP2533774B1 (sl)
JP (1) JP5634529B2 (sl)
KR (1) KR20120117936A (sl)
CN (1) CN102781437B (sl)
AR (1) AR080150A1 (sl)
AU (1) AU2011214190B2 (sl)
BR (1) BR112012020169A2 (sl)
CA (1) CA2789082C (sl)
CY (1) CY1120009T1 (sl)
DK (1) DK2533774T3 (sl)
EA (1) EA023473B1 (sl)
ES (1) ES2667856T3 (sl)
FR (1) FR2956031B1 (sl)
GE (1) GEP20166456B (sl)
HK (1) HK1177897A1 (sl)
HR (1) HRP20180537T1 (sl)
HU (1) HUE037098T2 (sl)
LT (1) LT2533774T (sl)
MA (1) MA34129B1 (sl)
ME (1) ME03047B (sl)
MX (1) MX2012009087A (sl)
MY (1) MY158112A (sl)
NO (1) NO2533774T3 (sl)
NZ (1) NZ601452A (sl)
PL (1) PL2533774T3 (sl)
PT (1) PT2533774T (sl)
RS (1) RS56932B1 (sl)
SG (1) SG182748A1 (sl)
SI (1) SI2533774T1 (sl)
TR (1) TR201802155T4 (sl)
UA (1) UA104368C2 (sl)
WO (1) WO2011098689A2 (sl)
ZA (1) ZA201205566B (sl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2810656T3 (pl) * 2013-06-06 2018-01-31 Zentiva Ks Preparaty agomelatyny zawierające agomelatynę w postaci kokryształów
CN103655499B (zh) * 2013-12-23 2015-07-22 天津泰普药品科技发展有限公司 一种稳定的晶x型阿戈美拉汀片剂及其制备方法
KR102039582B1 (ko) 2018-12-12 2019-11-01 주식회사 라파스 인장 공정으로 제조하기에 적합한 마이크로니들 재료의 적합성 시험 방법 및 이를 포함하는 마이크로니들 제조 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658818B1 (fr) 1990-02-27 1993-12-31 Adir Cie Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5618824A (en) * 1994-03-09 1997-04-08 Merrell Pharmaceuticals Inc. Treatment of obsessive-compulsive disorders with 5-HT2 antagonists
AR047553A1 (es) * 2003-07-04 2006-01-25 Lundbeck & Co As H La combinacion de un inhibidor de reabsorcion de serotonina y agomelatina
FR2866335B1 (fr) * 2004-02-13 2006-05-26 Servier Lab Nouveau procede de synthese de l'agomelatine
JP2008531714A (ja) * 2005-03-04 2008-08-14 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 不安障害の治療用及び/又は予防用の医薬組成物
FR2899472B1 (fr) * 2006-04-07 2008-09-12 Servier Lab Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble anxiete generalisee
KR20090029200A (ko) * 2006-05-22 2009-03-20 반다 파마슈티칼즈, 인코퍼레이티드. 우울증 질환에 대한 치료
WO2008035177A2 (en) * 2006-09-18 2008-03-27 Copharm Combination of mt1 and mt2 melatonin receptor agonists and a norepinephrine/dopamine reuptake inhibitor

Also Published As

Publication number Publication date
AR080150A1 (es) 2012-03-14
HK1177897A1 (en) 2013-08-30
HUE037098T2 (hu) 2018-08-28
EA201201123A1 (ru) 2013-03-29
EP2533774A2 (fr) 2012-12-19
PT2533774T (pt) 2018-02-27
GEP20166456B (en) 2016-04-11
MX2012009087A (es) 2012-09-07
EP2533774B1 (fr) 2018-01-31
CN102781437A (zh) 2012-11-14
WO2011098689A2 (fr) 2011-08-18
FR2956031B1 (fr) 2012-03-02
FR2956031A1 (fr) 2011-08-12
NO2533774T3 (sl) 2018-06-30
NZ601452A (en) 2014-11-28
HRP20180537T1 (hr) 2018-05-04
UA104368C2 (ru) 2014-01-27
BR112012020169A2 (pt) 2020-11-03
JP2013519659A (ja) 2013-05-30
TR201802155T4 (tr) 2018-03-21
DK2533774T3 (en) 2018-05-07
MA34129B1 (fr) 2013-04-03
PL2533774T3 (pl) 2018-06-29
WO2011098689A3 (fr) 2011-12-08
SG182748A1 (en) 2012-08-30
RS56932B1 (sr) 2018-05-31
MY158112A (en) 2016-08-30
LT2533774T (lt) 2018-02-26
ME03047B (me) 2018-10-20
AU2011214190A1 (en) 2012-08-16
CY1120009T1 (el) 2018-12-12
EA023473B1 (ru) 2016-06-30
CA2789082A1 (fr) 2011-08-18
ZA201205566B (en) 2013-09-25
CN102781437B (zh) 2014-07-30
KR20120117936A (ko) 2012-10-24
CA2789082C (fr) 2015-11-24
JP5634529B2 (ja) 2014-12-03
ES2667856T3 (es) 2018-05-14
AU2011214190B2 (en) 2013-04-18
US20120309838A1 (en) 2012-12-06

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