SI2519505T1 - Terciarni derivati 8-hidroksikinolin-7-karboksamida in njihove uporabe - Google Patents

Terciarni derivati 8-hidroksikinolin-7-karboksamida in njihove uporabe

Info

Publication number
SI2519505T1
SI2519505T1 SI201030974T SI201030974T SI2519505T1 SI 2519505 T1 SI2519505 T1 SI 2519505T1 SI 201030974 T SI201030974 T SI 201030974T SI 201030974 T SI201030974 T SI 201030974T SI 2519505 T1 SI2519505 T1 SI 2519505T1
Authority
SI
Slovenia
Prior art keywords
hydroxyquinoline
tertiary
carboxamide derivatives
carboxamide
derivatives
Prior art date
Application number
SI201030974T
Other languages
English (en)
Slovenian (sl)
Inventor
Stefania Gagliardi
Sordo Simone Del
Federico Mailland
Michela Legora
Original Assignee
Polichem S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42026678&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2519505(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Polichem S.A. filed Critical Polichem S.A.
Publication of SI2519505T1 publication Critical patent/SI2519505T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SI201030974T 2009-12-29 2010-12-28 Terciarni derivati 8-hidroksikinolin-7-karboksamida in njihove uporabe SI2519505T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09180902A EP2345643A1 (en) 2009-12-29 2009-12-29 New tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof
EP10800763.4A EP2519505B1 (en) 2009-12-29 2010-12-28 Tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof
PCT/EP2010/070790 WO2011080264A1 (en) 2009-12-29 2010-12-28 New tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof

Publications (1)

Publication Number Publication Date
SI2519505T1 true SI2519505T1 (sl) 2015-08-31

Family

ID=42026678

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201030974T SI2519505T1 (sl) 2009-12-29 2010-12-28 Terciarni derivati 8-hidroksikinolin-7-karboksamida in njihove uporabe

Country Status (37)

Country Link
US (1) US8729098B2 (enExample)
EP (2) EP2345643A1 (enExample)
JP (1) JP5808754B2 (enExample)
KR (1) KR101666505B1 (enExample)
CN (2) CN102686566A (enExample)
AU (1) AU2010338267B2 (enExample)
BR (1) BR112012015728A2 (enExample)
CA (1) CA2783213C (enExample)
CL (1) CL2012001757A1 (enExample)
CY (1) CY1116493T1 (enExample)
DK (1) DK2519505T3 (enExample)
DO (1) DOP2012000186A (enExample)
EA (1) EA025563B1 (enExample)
EC (1) ECSP12012007A (enExample)
ES (1) ES2540327T3 (enExample)
GE (1) GEP20156244B (enExample)
GT (1) GT201200216A (enExample)
HR (1) HRP20150749T1 (enExample)
HU (1) HUE027220T2 (enExample)
IL (1) IL220427A (enExample)
MA (1) MA33829B1 (enExample)
MX (1) MX2012007748A (enExample)
MY (1) MY161869A (enExample)
NI (1) NI201200114A (enExample)
NZ (1) NZ600788A (enExample)
PE (1) PE20130179A1 (enExample)
PH (1) PH12012501326A1 (enExample)
PL (1) PL2519505T3 (enExample)
PT (1) PT2519505E (enExample)
RS (1) RS54096B1 (enExample)
SG (1) SG181586A1 (enExample)
SI (1) SI2519505T1 (enExample)
SM (1) SMT201500182B (enExample)
TN (1) TN2012000320A1 (enExample)
UA (1) UA107949C2 (enExample)
WO (1) WO2011080264A1 (enExample)
ZA (1) ZA201204347B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2345642A1 (en) * 2009-12-29 2011-07-20 Polichem S.A. Secondary 8-hydroxyquinoline-7-carboxamide derivatives for use as antifungal agents
EP2345641A1 (en) * 2009-12-29 2011-07-20 Polichem S.A. New secondary 8-hydroxyquinoline-7-carboxamide derivatives
CN104185624B (zh) * 2012-02-24 2016-10-12 弗·哈夫曼-拉罗切有限公司 抗病毒化合物
ES2749512T3 (es) 2012-10-02 2020-03-20 Inst Nat Sante Rech Med Derivados de tetrahidroquinolina y su uso como inhibidores de Epac
US8697753B1 (en) 2013-02-07 2014-04-15 Polichem Sa Method of treating onychomycosis
USD976093S1 (en) 2020-09-22 2023-01-24 Milwaukee Electric Tool Corporation Staple collation
CN220302508U (zh) 2020-09-22 2024-01-05 米沃奇电动工具公司 动力式紧固件驱动器及钉排
WO2022094190A2 (en) 2020-10-30 2022-05-05 Milwaukee Electric Tool Corporation Powered fastener driver

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US326328A (en) 1885-09-15 Broiler
US326330A (en) 1885-09-15 Harness-support
DE540842C (de) 1930-08-06 1931-12-28 Chinosol Fabrik Akt Ges Verfahren zur Darstellung der 8-Acetyloxychinolin-7-carbonsaeure
CN1180995A (zh) 1995-04-08 1998-05-06 巴斯福股份公司 防治有害真菌的方法
US6194413B1 (en) * 1995-11-13 2001-02-27 Smithkline Beecham Corporation Hemoregulatory compounds
AU4172197A (en) 1996-09-10 1998-04-02 Pharmacia & Upjohn Company 8-hydroxy-7-substituted quinolines as anti-viral agents
WO1999016747A1 (en) * 1997-09-30 1999-04-08 Daiichi Pharmaceutical Co., Ltd. Sulfonyl derivatives
JP2001294572A (ja) * 2000-02-09 2001-10-23 Dai Ichi Seiyaku Co Ltd 新規スルホニル誘導体
AU1532802A (en) 2000-10-12 2002-04-22 Merck & Co Inc Aza- and polyaza-naphthalenyl-carboxamides useful as hiv integrase inhibitors
EP1326865B1 (en) 2000-10-12 2009-05-06 Merck & Co., Inc. Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors
CN1659143A (zh) 2001-03-01 2005-08-24 盐野义制药株式会社 具有hiv整合酶抑制活性的含氮杂芳基化合物
ATE404537T1 (de) 2002-08-13 2008-08-15 Shionogi & Co Heterocyclische verbindungen mit hiv-integrase- hemmender wirkung
US7932272B2 (en) * 2003-09-30 2011-04-26 Eisai R&D Management Co., Ltd. Antifungal agent containing heterocyclic compound
FR2889192A1 (fr) * 2005-07-27 2007-02-02 Cytomics Systems Sa Composes antifongiques, compositions contenant ces composes et leurs utilisations
EP2059305A2 (en) * 2006-07-26 2009-05-20 Novartis Ag Inhibitors of undecaprenyl pyrophosphate synthase
WO2009140215A2 (en) * 2008-05-11 2009-11-19 Geraghty, Erin Method for treating drug-resistant bacterial and other infections with clioquinol, phanquinone, and related compounds
UA102336C2 (uk) * 2009-11-10 2013-06-25 Пфайзер Інк. N1-ПІРАЗОЛСПІРОКЕТОНИ ЯК ІНГІБІТОРИ АЦЕТИЛ-СоА-КАРБОКСИЛАЗ
WO2011075630A1 (en) * 2009-12-18 2011-06-23 Incyte Corporation Substituted fused aryl and heteroaryl derivatives as pi3k inhibitors
EP2345642A1 (en) * 2009-12-29 2011-07-20 Polichem S.A. Secondary 8-hydroxyquinoline-7-carboxamide derivatives for use as antifungal agents
EP2345641A1 (en) * 2009-12-29 2011-07-20 Polichem S.A. New secondary 8-hydroxyquinoline-7-carboxamide derivatives

Also Published As

Publication number Publication date
MY161869A (en) 2017-05-15
IL220427A (en) 2015-04-30
CA2783213A1 (en) 2011-07-07
WO2011080264A1 (en) 2011-07-07
NZ600788A (en) 2013-08-30
EP2345643A1 (en) 2011-07-20
KR20120101563A (ko) 2012-09-13
GEP20156244B (en) 2015-02-10
AU2010338267B2 (en) 2014-03-27
PT2519505E (pt) 2015-09-03
SG181586A1 (en) 2012-07-30
US8729098B2 (en) 2014-05-20
CN102686566A (zh) 2012-09-19
EP2519505A1 (en) 2012-11-07
KR101666505B1 (ko) 2016-10-14
AU2010338267A2 (en) 2012-07-26
EA201270670A1 (ru) 2013-03-29
JP2013515755A (ja) 2013-05-09
US20120309751A1 (en) 2012-12-06
ECSP12012007A (es) 2012-08-31
HRP20150749T1 (hr) 2015-08-14
DOP2012000186A (es) 2013-01-15
GT201200216A (es) 2014-12-26
MA33829B1 (fr) 2012-12-03
NI201200114A (es) 2013-04-22
PH12012501326A1 (en) 2015-04-01
MX2012007748A (es) 2012-08-03
HUE027220T2 (hu) 2016-10-28
JP5808754B2 (ja) 2015-11-10
ZA201204347B (en) 2013-09-25
PE20130179A1 (es) 2013-02-24
PL2519505T3 (pl) 2015-11-30
DK2519505T3 (en) 2015-06-29
CY1116493T1 (el) 2017-03-15
TN2012000320A1 (en) 2013-12-12
AU2010338267A1 (en) 2012-07-19
EP2519505B1 (en) 2015-05-27
EA025563B1 (ru) 2017-01-30
CN105384685A (zh) 2016-03-09
ES2540327T3 (es) 2015-07-09
CA2783213C (en) 2017-09-12
CL2012001757A1 (es) 2013-03-22
RS54096B1 (sr) 2015-10-30
SMT201500182B (it) 2015-09-07
BR112012015728A2 (pt) 2019-09-24
HK1178526A1 (en) 2013-09-13
UA107949C2 (xx) 2015-03-10

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