SI2494356T1 - Preizkusi za detektiranje protiteles, specifičnih za terapevtska protitelesa proti IgE, in njihova uporaba pri anafilaksi - Google Patents

Preizkusi za detektiranje protiteles, specifičnih za terapevtska protitelesa proti IgE, in njihova uporaba pri anafilaksi

Info

Publication number
SI2494356T1
SI2494356T1 SI201031455A SI201031455A SI2494356T1 SI 2494356 T1 SI2494356 T1 SI 2494356T1 SI 201031455 A SI201031455 A SI 201031455A SI 201031455 A SI201031455 A SI 201031455A SI 2494356 T1 SI2494356 T1 SI 2494356T1
Authority
SI
Slovenia
Prior art keywords
anaphylaxis
assays
therapeutic anti
antibodies
detecting
Prior art date
Application number
SI201031455A
Other languages
English (en)
Inventor
Saloumeh Fischer
Dana L. Baker
Henry B. Lowman
Gerald R. Nakamura
Original Assignee
Genentech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech, Inc. filed Critical Genentech, Inc.
Publication of SI2494356T1 publication Critical patent/SI2494356T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/686—Anti-idiotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders
SI201031455A 2009-10-26 2010-10-26 Preizkusi za detektiranje protiteles, specifičnih za terapevtska protitelesa proti IgE, in njihova uporaba pri anafilaksi SI2494356T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25505209P 2009-10-26 2009-10-26
PCT/US2010/054160 WO2011056606A1 (en) 2009-10-26 2010-10-26 Assays for detecting antibodies specific to therapeutic anti-ige antibodies and their use in anaphylaxis
EP10828867.1A EP2494356B1 (en) 2009-10-26 2010-10-26 Assays for detecting antibodies specific to therapeutic anti-ige antibodies and their use in anaphylaxis

Publications (1)

Publication Number Publication Date
SI2494356T1 true SI2494356T1 (sl) 2017-07-31

Family

ID=43970265

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201031455A SI2494356T1 (sl) 2009-10-26 2010-10-26 Preizkusi za detektiranje protiteles, specifičnih za terapevtska protitelesa proti IgE, in njihova uporaba pri anafilaksi

Country Status (19)

Country Link
US (1) US9315583B2 (sl)
EP (1) EP2494356B1 (sl)
JP (1) JP6139885B2 (sl)
KR (1) KR101832510B1 (sl)
CN (1) CN102695956B (sl)
AU (1) AU2010315470B2 (sl)
BR (1) BR112012009846B8 (sl)
CA (1) CA2778810C (sl)
DK (1) DK2494356T3 (sl)
HK (1) HK1175538A1 (sl)
HU (1) HUE033492T2 (sl)
IL (1) IL219337A (sl)
MX (1) MX344935B (sl)
MY (1) MY182750A (sl)
NZ (1) NZ599600A (sl)
RU (1) RU2642295C2 (sl)
SI (1) SI2494356T1 (sl)
WO (1) WO2011056606A1 (sl)
ZA (1) ZA201202999B (sl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3572796B8 (en) 2008-10-27 2023-01-18 Genalyte, Inc. Biosensors based on optical probing and sensing
WO2013066986A1 (en) * 2011-10-31 2013-05-10 Puget Sound Blood Genter Antibody response phenotyping
WO2013096791A1 (en) 2011-12-23 2013-06-27 Genentech, Inc. Process for making high concentration protein formulations
EP3084439B1 (en) * 2013-12-20 2018-09-19 Phadia AB Analysis of antibodies
TWI691512B (zh) 2015-02-20 2020-04-21 日商橘生藥品工業股份有限公司 Ｆｃ融合高親和性ＩｇＥ受體α鏈
GB201610198D0 (en) 2016-06-10 2016-07-27 Ucb Biopharma Sprl Anti-ige antibodies
KR101957411B1 (ko) 2017-09-13 2019-03-12 (주)뷰티화장품 생약 추출물 함포 펙틴 마이크로캡슐을 포함하는 피부 개선용 화장료 조성물
US20220347236A1 (en) * 2018-01-12 2022-11-03 Gl INNOVATION, INC. Composition comprising probiotics and polypeptide having binding affinity for ige and use thereof
WO2019212993A1 (en) * 2018-04-30 2019-11-07 Genalyte, Inc. Methods and compositions for point of care measurement of the bioavailability of therapeutic biologics
WO2020172496A1 (en) * 2019-02-21 2020-08-27 Ding Qinxue Method of removing non-specific binding signals using microparticles
CA3145382A1 (en) * 2019-07-08 2021-01-14 Gi Innovation, Inc. Polypeptide dimer with high sialic acid content, comprising extracellular domain of alpha subunit of ige fc receptor, and pharmaceutical composition comprising same
CN112285351A (zh) * 2019-07-22 2021-01-29 上海益诺思生物技术股份有限公司 一种抗IgE单抗的ELISA检测方法
CN110358738B (zh) * 2019-08-22 2021-08-13 中国食品药品检定研究院 一种稳定测定抗IgE抗体药物生物学活性的方法
JP7062803B1 (ja) * 2021-03-31 2022-05-06 積水メディカル株式会社 抗薬物抗体測定方法
CN114047343B (zh) * 2022-01-13 2022-05-31 美迪西普亚医药科技(上海)有限公司 双耐受型抗IgE单抗药物的免疫原性分析试剂盒及其使用方法和应用
CN116699147A (zh) * 2023-08-04 2023-09-05 军科正源（北京）药物研究有限责任公司 检测总IgE含量的方法以及相关试剂盒

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE337223B (sl) * 1967-05-23 1971-08-02 Pharmacia Ab
US3720760A (en) * 1968-09-06 1973-03-13 Pharmacia Ab Method for determining the presence of reagin-immunoglobulins(reagin-ig)directed against certain allergens,in aqueous samples
US3645090A (en) * 1969-06-19 1972-02-29 Citizen Watch Co Ltd Day-date quick-adjuster for calender timepiece
US3691016A (en) * 1970-04-17 1972-09-12 Monsanto Co Process for the preparation of insoluble enzymes
US3940475A (en) * 1970-06-11 1976-02-24 Biological Developments, Inc. Radioimmune method of assaying quantitatively for a hapten
CA1023287A (en) * 1972-12-08 1977-12-27 Boehringer Mannheim G.M.B.H. Process for the preparation of carrier-bound proteins
US4195128A (en) * 1976-05-03 1980-03-25 Bayer Aktiengesellschaft Polymeric carrier bound ligands
US4330440A (en) * 1977-02-08 1982-05-18 Development Finance Corporation Of New Zealand Activated matrix and method of activation
CA1093991A (en) * 1977-02-17 1981-01-20 Hideo Hirohara Enzyme immobilization with pullulan gel
US4229537A (en) * 1978-02-09 1980-10-21 New York University Preparation of trichloro-s-triazine activated supports for coupling ligands
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4459359A (en) * 1981-11-19 1984-07-10 New York Blood Center, Inc. Sensitive immunoassays of antigens or antibodies sequestered within immune complexes
US4737462A (en) * 1982-10-19 1988-04-12 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4518584A (en) * 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
US4683136A (en) * 1985-03-06 1987-07-28 Scripps Clinic And Research Foundation Proteinaceous antigens with conformation-independent and conformation-dependent determinants
US4737456A (en) * 1985-05-09 1988-04-12 Syntex (U.S.A.) Inc. Reducing interference in ligand-receptor binding assays
GB8823869D0 (en) * 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US5175384A (en) * 1988-12-05 1992-12-29 Genpharm International Transgenic mice depleted in mature t-cells and methods for making transgenic mice
SG48759A1 (en) 1990-01-12 2002-07-23 Abgenix Inc Generation of xenogenic antibodies
US5661016A (en) * 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5633425A (en) * 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5625126A (en) * 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5545806A (en) * 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
ES2108048T3 (es) * 1990-08-29 1997-12-16 Genpharm Int Produccion y utilizacion de animales inferiores transgenicos capaces de producir anticuerpos heterologos.
WO1992017207A1 (en) 1991-03-26 1992-10-15 Tanox Biosystems, Inc. MONOCLONAL ANTIBODIES WHICH BIND TO SECRETED AND MEMBRANE-BOUND IgE, BUT NOT TO IgE ON BASOPHILS
JPH0772150A (ja) * 1993-09-02 1995-03-17 Tonen Corp ＩｇＥの測定方法
CA2219361C (en) 1995-04-27 2012-02-28 Abgenix, Inc. Human antibodies derived from immunized xenomice
AU2466895A (en) 1995-04-28 1996-11-18 Abgenix, Inc. Human antibodies derived from immunized xenomice
DE19544393A1 (de) 1995-11-15 1997-05-22 Hoechst Schering Agrevo Gmbh Synergistische herbizide Mischungen
EP2305027B1 (en) 1996-12-03 2014-07-02 Amgen Fremont Inc. Transgenic mammals having human Ig loci including plural VH and Vkappa regions and antibodies produced therefrom
US5994511A (en) * 1997-07-02 1999-11-30 Genentech, Inc. Anti-IgE antibodies and methods of improving polypeptides
US6172213B1 (en) * 1997-07-02 2001-01-09 Genentech, Inc. Anti-IgE antibodies and method of improving polypeptides
JP4427182B2 (ja) * 1997-09-22 2010-03-03 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド 抗原を安定化するための緩衝液
PT1324776E (pt) * 2000-10-12 2009-12-23 Genentech Inc Formulações de proteína concentradas de viscosidade reduzida
JP2006500923A (ja) * 2002-08-01 2006-01-12 ノースウェスタン ユニバーシティ ＩｇＥタンパク質の変異体およびその使用
DK2407485T3 (en) 2003-02-01 2016-03-21 Tanox Inc Anti-human IgE antibodies with high affinity
US20050158303A1 (en) * 2003-04-04 2005-07-21 Genentech, Inc. Methods of treating IgE-mediated disorders comprising the administration of high concentration anti-IgE antibody formulations
PT1610820E (pt) * 2003-04-04 2010-12-16 Novartis Ag Formulações de elevada concentração de anticorpos e proteínas
DE602004026284D1 (de) * 2004-07-01 2010-05-12 Biomay Ag Hausstaubmilbenallergen
CA2577405A1 (en) 2004-09-02 2006-03-16 Genentech, Inc. Anti-fc-gamma riib receptor antibody and uses therefor
ATE439598T1 (de) * 2005-10-17 2009-08-15 Pls Design Gmbh Chimäre zwischen einer alpha-kette eines humanen ige rezeptor und konstanten immunoglobulin- domänen von vögeln zur determination von serum ige.
US20070184501A1 (en) * 2006-02-07 2007-08-09 Beckman Coulter, Inc. Blocker reagent for reduction of heterophile interferences
WO2008028068A2 (en) * 2006-08-30 2008-03-06 Genentech, Inc. NON-HUMAN PRIMATE FCεR1α POLYPEPTIDES

Also Published As

Publication number Publication date
DK2494356T3 (en) 2017-05-15
IL219337A (en) 2017-06-29
MX344935B (es) 2017-01-11
CN102695956A (zh) 2012-09-26
JP2013508740A (ja) 2013-03-07
MX2012004833A (es) 2012-07-04
EP2494356A1 (en) 2012-09-05
KR101832510B1 (ko) 2018-02-26
HK1175538A1 (zh) 2013-07-05
BR112012009846B8 (pt) 2021-05-25
CA2778810A1 (en) 2011-05-12
IL219337A0 (en) 2012-06-28
US20110183363A1 (en) 2011-07-28
NZ599600A (en) 2015-04-24
JP6139885B2 (ja) 2017-05-31
AU2010315470B2 (en) 2016-05-05
BR112012009846B1 (pt) 2021-04-20
US9315583B2 (en) 2016-04-19
WO2011056606A8 (en) 2012-05-18
EP2494356B1 (en) 2017-03-15
KR20120116400A (ko) 2012-10-22
RU2642295C2 (ru) 2018-01-24
MY182750A (en) 2021-02-05
AU2010315470A1 (en) 2012-05-24
EP2494356A4 (en) 2013-07-03
HUE033492T2 (en) 2017-12-28
WO2011056606A1 (en) 2011-05-12
CN102695956B (zh) 2015-12-09
CA2778810C (en) 2018-09-04
BR112012009846A2 (pt) 2017-02-21
ZA201202999B (en) 2013-06-26
RU2012121559A (ru) 2013-12-10

Similar Documents

Publication Publication Date Title
ZA201202999B (en) Assays for detecting antibodies specific to therapeutic anti-ige antibodies and their use in anaphylaxis
IL278007A (en) Anti-PD-L1 antibodies and their use to enhance T cell function
HK1251260A1 (zh) Bcl-2家族的異二聚體特異性抗體及其用途
HK1216028A1 (zh) 定向於 的抗體及其用途
IL230771A (en) Antibody from a person that binds pcsk9
IL232276A0 (en) Antibodies to 6-il and their uses
IL214779A0 (en) Fully human antibodies specific to cadm1
IL217209A0 (en) Novel antibodies and their uses in therapeutic and diagnostic methods
GB0817703D0 (en) Improvements in and relating to assaying of waste
EP2484693A4 (en) ANTI-AMYLOID-A3 ANTIBODIES OF HUMAN SERUM AND USE THEREOF
TH129814B (th) แอนติบอดีต่อ nr10 และการใช้ประโยชน์ของมัน
GB0911062D0 (en) Improvements in and relating to assaying of waste
GB0918461D0 (en) Improvements in and relating to analysis