SI2454266T1 - Citratna sol 9e-15-(2-pirolidin-1-il-etoksi)-7,12,25-trioksa-19,21,24-triaza-tetra- ciklo (18.3.1.1(2,5).1(14)18)heksakosa-1(24),2,4,9,14,16,18(26),20,22- nonaena - Google Patents

Citratna sol 9e-15-(2-pirolidin-1-il-etoksi)-7,12,25-trioksa-19,21,24-triaza-tetra- ciklo (18.3.1.1(2,5).1(14)18)heksakosa-1(24),2,4,9,14,16,18(26),20,22- nonaena

Info

Publication number
SI2454266T1
SI2454266T1 SI201030347T SI201030347T SI2454266T1 SI 2454266 T1 SI2454266 T1 SI 2454266T1 SI 201030347 T SI201030347 T SI 201030347T SI 201030347 T SI201030347 T SI 201030347T SI 2454266 T1 SI2454266 T1 SI 2454266T1
Authority
SI
Slovenia
Prior art keywords
chexacosa
nonaene
trioxa
triaza
pyrrolidin
Prior art date
Application number
SI201030347T
Other languages
English (en)
Slovenian (sl)
Inventor
Brian Dymock
Cheng Hsia Angeline Lee
Anthony Deodaunia William
Original Assignee
Cell Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Therapeutics, Inc. filed Critical Cell Therapeutics, Inc.
Publication of SI2454266T1 publication Critical patent/SI2454266T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SI201030347T 2009-07-15 2010-07-14 Citratna sol 9e-15-(2-pirolidin-1-il-etoksi)-7,12,25-trioksa-19,21,24-triaza-tetra- ciklo (18.3.1.1(2,5).1(14)18)heksakosa-1(24),2,4,9,14,16,18(26),20,22- nonaena SI2454266T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22560909P 2009-07-15 2009-07-15
EP10737645.1A EP2454266B1 (en) 2009-07-15 2010-07-14 9e-15-(2-pyrrolidin-1-yl-ethoxy)-7,12,25-trioxa-19,21,24-triaza- tetracyclo[18.3.1.1(2,5).1(14)18)]hexacosa-1(24),2,4,9,14,16,18(26),20,22-nonaene citrate salt
PCT/SG2010/000265 WO2011008172A1 (en) 2009-07-15 2010-07-14 9e-15-(2-pyrrolidin-1-yl-ethoxy)-7,12,25-trioxa-19,21,24-triaza- tetracyclo[18.3.1.1(2,5).1(14)18)]hexacosa-1(24),2,4,9,14,16,18(26),20,22-nonaene citrate salt

Publications (1)

Publication Number Publication Date
SI2454266T1 true SI2454266T1 (sl) 2013-10-30

Family

ID=42790728

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201030347T SI2454266T1 (sl) 2009-07-15 2010-07-14 Citratna sol 9e-15-(2-pirolidin-1-il-etoksi)-7,12,25-trioksa-19,21,24-triaza-tetra- ciklo (18.3.1.1(2,5).1(14)18)heksakosa-1(24),2,4,9,14,16,18(26),20,22- nonaena

Country Status (18)

Country Link
US (1) US9062074B2 (enExample)
EP (1) EP2454266B1 (enExample)
JP (2) JP6013911B2 (enExample)
CN (1) CN102762577B (enExample)
AR (2) AR077483A1 (enExample)
BR (1) BR112012000750B1 (enExample)
CA (1) CA2768210C (enExample)
DK (1) DK2454266T3 (enExample)
ES (1) ES2429525T3 (enExample)
HR (1) HRP20130941T1 (enExample)
MX (1) MX2012000680A (enExample)
PL (1) PL2454266T3 (enExample)
PT (1) PT2454266E (enExample)
RU (1) RU2543721C2 (enExample)
SI (1) SI2454266T1 (enExample)
SM (1) SMT201300112B (enExample)
TW (1) TWI537276B (enExample)
WO (1) WO2011008172A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2966753A1 (en) 2014-11-17 2016-05-26 Arno Therapeutics, Inc. Onapristone extended-release compositions and methods
AU2016326657B2 (en) 2015-09-25 2019-10-24 Context Biopharma, Inc. Methods of making onapristone intermediates
CA3008422A1 (en) 2015-12-15 2017-06-22 Context Biopharma Inc. Amorphous onapristone compositions and methods of making the same
US20180148471A1 (en) 2016-11-30 2018-05-31 Arno Therapeutics, Inc. Methods for onapristone synthesis dehydration and deprotection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY110603A (en) * 1993-05-27 1998-08-29 Novartis Ag Tetrahydropyran derivatives
US7151096B2 (en) * 2003-03-05 2006-12-19 Irm Llc Cyclic compounds and compositions as protein kinase inhibitors
CN101365703B (zh) * 2005-11-16 2013-11-06 S*Bio私人有限公司 杂烷基连接的嘧啶衍生物

Also Published As

Publication number Publication date
CN102762577A (zh) 2012-10-31
AR114987A2 (es) 2020-11-11
EP2454266A1 (en) 2012-05-23
JP2012533539A (ja) 2012-12-27
WO2011008172A1 (en) 2011-01-20
CA2768210C (en) 2017-08-15
ES2429525T3 (es) 2013-11-15
PL2454266T3 (pl) 2014-01-31
AR077483A1 (es) 2011-08-31
HRP20130941T1 (hr) 2013-11-08
MX2012000680A (es) 2012-02-28
BR112012000750A8 (pt) 2018-02-06
TWI537276B (zh) 2016-06-11
EP2454266B1 (en) 2013-07-10
CA2768210A1 (en) 2011-01-20
BR112012000750B1 (pt) 2021-05-25
BR112012000750A2 (pt) 2016-08-09
SMT201300112B (it) 2013-11-08
JP2015164941A (ja) 2015-09-17
US9062074B2 (en) 2015-06-23
RU2012105044A (ru) 2013-08-20
HK1178159A1 (en) 2013-09-06
DK2454266T3 (da) 2013-09-08
TW201107336A (en) 2011-03-01
US20120196876A1 (en) 2012-08-02
RU2543721C2 (ru) 2015-03-10
JP6013911B2 (ja) 2016-10-25
CN102762577B (zh) 2015-01-07
PT2454266E (pt) 2013-10-10

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